Christophers S Kovacs

Summary

Affiliation: Memorial University of Newfoundland
Country: Canada

Publications

  1. ncbi Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies
    Christophers S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    Am J Clin Nutr 88:520S-528S. 2008
  2. doi Calcium, phosphorus, and bone metabolism in the fetus and newborn
    Christopher S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, NL, Canada Electronic address
    Early Hum Dev 91:623-8. 2015
  3. doi Empagliflozin as Add-on Therapy to Pioglitazone With or Without Metformin in Patients With Type 2 Diabetes Mellitus
    Christopher S Kovacs
    Health Sciences Centre, Memorial University, St John s, Newfoundland, Canada Electronic address
    Clin Ther 37:1773-88.e1. 2015
  4. doi Presentation and management of osteoporosis presenting in association with pregnancy or lactation
    C S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada, A1B 3V6
    Osteoporos Int 26:2223-41. 2015
  5. doi Bone metabolism in the fetus and neonate
    Christopher S Kovacs
    Faculty of Medicine, Memorial University of Newfoundland, Health Sciences Centre, 300 Prince Philip Drive, St John s, NL, A1B 3V6, Canada
    Pediatr Nephrol 29:793-803. 2014
  6. pmc Lactating Ctcgrp nulls lose twice the normal bone mineral content due to fewer osteoblasts and more osteoclasts, whereas bone mass is fully restored after weaning in association with up-regulation of Wnt signaling and other novel genes
    Jillian N Collins
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada A1B 3V6
    Endocrinology 154:1400-13. 2013
  7. doi The role of vitamin D in pregnancy and lactation: insights from animal models and clinical studies
    Christopher S Kovacs
    Health Sciences Centre, Memorial University of Newfoundland, St John s, NL, Canada
    Annu Rev Nutr 32:97-123. 2012
  8. doi Calcium and bone metabolism disorders during pregnancy and lactation
    Christopher S Kovacs
    Health Sciences Centre, Memorial University of Newfoundland, St John s, Canada
    Endocrinol Metab Clin North Am 40:795-826. 2011
  9. pmc Physiological studies in heterozygous calcium sensing receptor (CaSR) gene-ablated mice confirm that the CaSR regulates calcitonin release in vivo
    Neva J Fudge
    Faculty of Medicine, Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, A1B 3V6 Canada
    BMC Physiol 4:5. 2004
  10. doi Bone development in the fetus and neonate: role of the calciotropic hormones
    Christopher S Kovacs
    Medicine Endocrinology and Metabolism, Obstetrics and Gynecology, and Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, Health Sciences Centre, 300 Prince Philip Drive, St John s, Newfoundland, A1B 3V6, Canada
    Curr Osteoporos Rep 9:274-83. 2011

Collaborators

Detail Information

Publications16

  1. ncbi Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies
    Christophers S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    Am J Clin Nutr 88:520S-528S. 2008
    ..In addition, the relation (if any) of vitamin D insufficiency in the fetus or neonate to long-term nonskeletal outcomes such as type 1 diabetes and other chronic diseases needs to be investigated...
  2. doi Calcium, phosphorus, and bone metabolism in the fetus and newborn
    Christopher S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, NL, Canada Electronic address
    Early Hum Dev 91:623-8. 2015
    ..Serum calcium increases and phosphorus declines over days. The intestines become the main source of mineral, while kidneys reabsorb mineral, and bone turnover contributes additional mineral to the circulation. ..
  3. doi Empagliflozin as Add-on Therapy to Pioglitazone With or Without Metformin in Patients With Type 2 Diabetes Mellitus
    Christopher S Kovacs
    Health Sciences Centre, Memorial University, St John s, Newfoundland, Canada Electronic address
    Clin Ther 37:1773-88.e1. 2015
    ..To investigate the long-term efficacy and safety of empagliflozin as add-on therapy to pioglitazone with or without metformin in patients with type 2 diabetes mellitus...
  4. doi Presentation and management of osteoporosis presenting in association with pregnancy or lactation
    C S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada, A1B 3V6
    Osteoporos Int 26:2223-41. 2015
    ..However, the need for such treatments is uncertain given that a progressive increase in bone mass subsequently occurs in most women who present with a fracture during pregnancy or lactation. ..
  5. doi Bone metabolism in the fetus and neonate
    Christopher S Kovacs
    Faculty of Medicine, Memorial University of Newfoundland, Health Sciences Centre, 300 Prince Philip Drive, St John s, NL, A1B 3V6, Canada
    Pediatr Nephrol 29:793-803. 2014
    ..However, even this postnatal function of calcitriol can be bypassed by increasing the calcium content of the diet or by administering calcium infusions. ..
  6. pmc Lactating Ctcgrp nulls lose twice the normal bone mineral content due to fewer osteoblasts and more osteoclasts, whereas bone mass is fully restored after weaning in association with up-regulation of Wnt signaling and other novel genes
    Jillian N Collins
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada A1B 3V6
    Endocrinology 154:1400-13. 2013
    ..Some of these genes are likely to promote bone formation during postweaning by stimulating the proliferation and activity of osteoblasts, inhibiting osteoclasts, and increasing energy use...
  7. doi The role of vitamin D in pregnancy and lactation: insights from animal models and clinical studies
    Christopher S Kovacs
    Health Sciences Centre, Memorial University of Newfoundland, St John s, NL, Canada
    Annu Rev Nutr 32:97-123. 2012
    ..Dosing recommendations during pregnancy and lactation should ensure that the baby is born vitamin D sufficient and maintained that way during infancy and beyond...
  8. doi Calcium and bone metabolism disorders during pregnancy and lactation
    Christopher S Kovacs
    Health Sciences Centre, Memorial University of Newfoundland, St John s, Canada
    Endocrinol Metab Clin North Am 40:795-826. 2011
    ..Although some women may experience fragility fractures as a consequence of pregnancy or lactation, for most women, parity and lactation do not affect the long-term risks of low bone density, osteoporosis, or fracture...
  9. pmc Physiological studies in heterozygous calcium sensing receptor (CaSR) gene-ablated mice confirm that the CaSR regulates calcitonin release in vivo
    Neva J Fudge
    Faculty of Medicine, Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, A1B 3V6 Canada
    BMC Physiol 4:5. 2004
    ..Ionized calcium was measured at baseline and 10 minutes, and serum calcitonin was measured on the 10 minute sample...
  10. doi Bone development in the fetus and neonate: role of the calciotropic hormones
    Christopher S Kovacs
    Medicine Endocrinology and Metabolism, Obstetrics and Gynecology, and Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, Health Sciences Centre, 300 Prince Philip Drive, St John s, Newfoundland, A1B 3V6, Canada
    Curr Osteoporos Rep 9:274-83. 2011
    ....
  11. doi Hemophilia, low bone mass, and osteopenia/osteoporosis
    Christopher S Kovacs
    Faculty of Medicine Endocrinology, Health Sciences Centre, Memorial University of Newfoundland, 300 Prince Philip Drive, St John s, Newfoundland, Canada A1B 3V6
    Transfus Apher Sci 38:33-40. 2008
    ....
  12. ncbi Calcium and bone disorders during pregnancy and lactation
    Christopher S Kovacs
    Basic Medical Sciences, Health Sciences Centre, 300 Prince Philip Drive, St John s, Newfoundland A1B 3V6, Canada
    Endocrinol Metab Clin North Am 35:21-51, v. 2006
  13. ncbi Calcium and bone metabolism during pregnancy and lactation
    Christopher S Kovacs
    Faculty of Medicine Endocrinology, Health Sciences Centre, Memorial University of Newfoundland, St John s, Canada
    J Mammary Gland Biol Neoplasia 10:105-18. 2005
    ....
  14. ncbi The vitamin D receptor is not required for fetal mineral homeostasis or for the regulation of placental calcium transfer in mice
    Christopher S Kovacs
    Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Dr, St John s, Newfoundland and Labrador, Canada
    Am J Physiol Endocrinol Metab 289:E133-44. 2005
    ..Absence of maternal VDR has global effects on fetal growth that were partly dependent on maternal calcium intake, but absence of maternal VDR did not specifically affect fetal mineral homeostasis...
  15. ncbi PTH regulates fetal blood calcium and skeletal mineralization independently of PTHrP
    C S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St John s, Newfoundland, Canada A1B 3V6
    Endocrinology 142:4983-93. 2001
    ....
  16. pmc Fetal parathyroids are not required to maintain placental calcium transport
    C S Kovacs
    Faculty of Medicine Endocrinology, Memorial University of Newfoundland, 300 Prince Philip Drive, St John s, Newfoundland A1B 3V6, Canada
    J Clin Invest 107:1007-15. 2001
    ..The findings in the Pthr1-null fetuses indicate that several tissues may contribute to the circulating PTHrP level in fetal mice...