Jacqueline Blundell

Summary

Affiliation: Memorial University of Newfoundland
Country: Canada

Publications

  1. pmc Block of glucocorticoid synthesis during re-activation inhibits extinction of an established fear memory
    Jacqueline Blundell
    Department of Psychology, Memorial University of Newfoundland, 232 Elizabeth Ave, St John s, Newfoundland A1B3X9, Canada
    Neurobiol Learn Mem 95:453-60. 2011
  2. doi request reprint The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, NF, A1B 3X9 Canada
    Behav Brain Res 189:180-90. 2008
  3. ncbi request reprint Role of NMDA receptors in the syndrome of behavioral changes produced by predator stress
    Jacqueline Blundell
    Department of Psychology, Memorial University, St John s, NF, Canada
    Physiol Behav 86:233-43. 2005
  4. doi request reprint A comparison of activation patterns of cells in selected prefrontal cortical and amygdala areas of rats which are more or less anxious in response to predator exposure or submersion stress
    Robert Adamec
    Memorial University, St John s, Newfoundland, Canada
    Physiol Behav 105:628-38. 2012
  5. ncbi request reprint Lasting anxiogenic effects of feline predator stress in mice: sex differences in vulnerability to stress and predicting severity of anxiogenic response from the stress experience
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, NF, Canada, A1B 3X9
    Physiol Behav 88:12-29. 2006
  6. ncbi request reprint Inhibition of mTOR kinase via rapamycin blocks persistent predator stress-induced hyperarousal
    Kathleen Fifield
    Department of Psychology, Memorial University of Newfoundland, 232 Elizabeth Ave, St John s, Newfoundland, Canada A1B 3X9
    Behav Brain Res 256:457-63. 2013
  7. doi request reprint Long lasting effects of predator stress on pCREB expression in brain regions involved in fearful and anxious behavior
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue St John s, NL, Canada
    Behav Brain Res 221:118-33. 2011
  8. ncbi request reprint Elevated pCREB in the PAG after exposure to the elevated plus maze in rats previously exposed to a cat
    Jacqueline Blundell
    Department of Psychology, Memorial University of Newfoundland and Labrador, St John s, Nfld, Canada A1B 3X9
    Behav Brain Res 175:285-95. 2006
  9. doi request reprint Activation patterns of cells in selected brain stem nuclei of more and less stress responsive rats in two animal models of PTSD - predator exposure and submersion stress
    Robert Adamec
    Dept of Psychology, Memorial University, St John s, Newfoundland, Canada
    Neuropharmacology 62:725-36. 2012
  10. ncbi request reprint Vulnerability to mild predator stress in serotonin transporter knockout mice
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, Nfld, Canada A1B 3X9
    Behav Brain Res 170:126-40. 2006

Collaborators

Detail Information

Publications20

  1. pmc Block of glucocorticoid synthesis during re-activation inhibits extinction of an established fear memory
    Jacqueline Blundell
    Department of Psychology, Memorial University of Newfoundland, 232 Elizabeth Ave, St John s, Newfoundland A1B3X9, Canada
    Neurobiol Learn Mem 95:453-60. 2011
    ..Here we examine the role of endogenous glucocorticoids in traumatic memory extinction...
  2. doi request reprint The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, NF, A1B 3X9 Canada
    Behav Brain Res 189:180-90. 2008
    ....
  3. ncbi request reprint Role of NMDA receptors in the syndrome of behavioral changes produced by predator stress
    Jacqueline Blundell
    Department of Psychology, Memorial University, St John s, NF, Canada
    Physiol Behav 86:233-43. 2005
    ..Components of this syndrome of behavioral changes likely depend on changes in separable neural substrates initiated in part by NMDA receptors as well as by other neurochemical means...
  4. doi request reprint A comparison of activation patterns of cells in selected prefrontal cortical and amygdala areas of rats which are more or less anxious in response to predator exposure or submersion stress
    Robert Adamec
    Memorial University, St John s, Newfoundland, Canada
    Physiol Behav 105:628-38. 2012
    ..The data suggest that preclinical markers of vulnerability/resilience in a given stress paradigm are at best suggestive, and translational value must ultimately be confirmed in humans...
  5. ncbi request reprint Lasting anxiogenic effects of feline predator stress in mice: sex differences in vulnerability to stress and predicting severity of anxiogenic response from the stress experience
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, NF, Canada, A1B 3X9
    Physiol Behav 88:12-29. 2006
    ..Moreover, stressors had no lasting effects on sugar solution consumption. Implications of these findings for modeling PTSD and using transgenic strains of mice to study lasting effects of stress on affect are discussed...
  6. ncbi request reprint Inhibition of mTOR kinase via rapamycin blocks persistent predator stress-induced hyperarousal
    Kathleen Fifield
    Department of Psychology, Memorial University of Newfoundland, 232 Elizabeth Ave, St John s, Newfoundland, Canada A1B 3X9
    Behav Brain Res 256:457-63. 2013
    ..Overall, these data suggest that mTOR activation may contribute to the development of acquired anxiety disorders such as PTSD. ..
  7. doi request reprint Long lasting effects of predator stress on pCREB expression in brain regions involved in fearful and anxious behavior
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue St John s, NL, Canada
    Behav Brain Res 221:118-33. 2011
    ..Identification of these changes may aid in understanding the neural mechanisms underlying acquired anxiety disorders such as PTSD...
  8. ncbi request reprint Elevated pCREB in the PAG after exposure to the elevated plus maze in rats previously exposed to a cat
    Jacqueline Blundell
    Department of Psychology, Memorial University of Newfoundland and Labrador, St John s, Nfld, Canada A1B 3X9
    Behav Brain Res 175:285-95. 2006
    ..If what happens in animals also occurs in humans, the findings of this study suggest that neural mechanisms of prior traumatic stress may interact with subsequent stress to reinforce psychopathology...
  9. doi request reprint Activation patterns of cells in selected brain stem nuclei of more and less stress responsive rats in two animal models of PTSD - predator exposure and submersion stress
    Robert Adamec
    Dept of Psychology, Memorial University, St John s, Newfoundland, Canada
    Neuropharmacology 62:725-36. 2012
    ..This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'...
  10. ncbi request reprint Vulnerability to mild predator stress in serotonin transporter knockout mice
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, Nfld, Canada A1B 3X9
    Behav Brain Res 170:126-40. 2006
    ..Findings suggest a role for abnormalities in 5-HT transmission in vulnerability to some of the lasting anxiogenic effects of species relevant stressors and possibly in vulnerability to PTSD...
  11. pmc Vulnerability to lasting anxiogenic effects of brief exposure to predator stimuli: sex, serotonin and other factors-relevance to PTSD
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, NF A1B 3X9, Canada
    Neurosci Biobehav Rev 32:1287-92. 2008
    ....
  12. pmc Dendritic morphology of amygdala and hippocampal neurons in more and less predator stress responsive rats and more and less spontaneously anxious handled controls
    Robert Adamec
    Memorial University, St John s, Newfoundland, Canada, A1B 3X9
    Behav Brain Res 226:133-46. 2012
    ..Significance of findings for animal models of anxiety and hyperarousal comorbidities of PTSD are discussed...
  13. ncbi request reprint Phosphorylated cyclic AMP response element binding protein expression induced in the periaqueductal gray by predator stress: its relationship to the stress experience, behavior and limbic neural plasticity
    Robert E Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, A1B 3X9, St John s, Newfoundland, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 27:1243-67. 2003
    ..Finally, consistent with cat and human studies, the right hemisphere appears particularly important in long-term response to stress...
  14. ncbi request reprint Relationship of the predatory attack experience to neural plasticity, pCREB expression and neuroendocrine response
    Robert E Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Ave, St John s, NL, Canada, A1B 3X9
    Neurosci Biobehav Rev 30:356-75. 2006
    ....
  15. ncbi request reprint Role of NMDA receptors in the lateralized potentiation of amygdala afferent and efferent neural transmission produced by predator stress
    Robert Adamec
    Department of Psychology, Memorial University, St John s, NF, Canada
    Physiol Behav 86:75-91. 2005
    ..In contrast, a lateral ACE-PAG pathway is implicated in mediating changes in startle habituation. Finally, consistent with cat and human studies, the right hemisphere appears particularly important in long term response to stress...
  16. ncbi request reprint Neural circuit changes mediating lasting brain and behavioral response to predator stress
    Robert E Adamec
    Dept of Psychology, Memorial University, 232 Elizabeth Ave, St John s, NL, Canada
    Neurosci Biobehav Rev 29:1225-41. 2005
    ..Findings will be discussed within the context of what is known about neural substrates activated by predator odor...
  17. ncbi request reprint Anxiolytic effects of kindling role of anatomical location of the kindling electrode in response to kindling of the right basolateral amygdala
    Robert Adamec
    Department of Psychology, Memorial University, St John s, Nfld, Canada A1B 3X9
    Brain Res 1024:44-58. 2004
    ....
  18. pmc Single rapamycin administration induces prolonged downward shift in defended body weight in rats
    Mark Hebert
    Department of Psychology, Memorial University of Newfoundland, St John s, Newfoundland, Canada
    PLoS ONE 9:e93691. 2014
    ..Thus, RAP and related compounds may be unique tools to investigate the mechanisms by which the defended level of body weight is determined; such compounds may also be used to complement weight loss strategy. ..
  19. ncbi request reprint Systemic inhibition of mTOR kinase via rapamycin disrupts consolidation and reconsolidation of auditory fear memory
    Phillip E Mac Callum
    Department of Psychology, Memorial University of Newfoundland, 232 Elizabeth Ave, St John s, Newfoundland A1B 3X9, Canada
    Neurobiol Learn Mem 112:176-85. 2014
    ....
  20. ncbi request reprint Protein synthesis and the mechanisms of lasting change in anxiety induced by severe stress
    Robert Adamec
    Department of Psychology, Memorial University, 232 Elizabeth Avenue, St John s, NF, A1B 3X9, Canada
    Behav Brain Res 167:270-86. 2006
    ..Since predator stress may model aspects of hyperarousal associated with post traumatic stress disorder (PTSD), implications of these findings for understanding of mechanisms of initiation of the disorder and for treatment are discussed...