Kelly A Meckling

Summary

Country: Canada

Publications

  1. ncbi Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, N1G 2W1 Ontario, Canada
    J Clin Endocrinol Metab 89:2717-23. 2004
  2. doi In vitro antioxidant synergism and antagonism between food extracts can lead to similar activities in H2O2-induced cell death, caspase-3 and MMP-2 activities in H9c2 cells
    Sunan Wang
    Guelph Food Research Center, Agriculture and Agri Food Canada, Guelph, Ontario, Canada
    J Sci Food Agric 92:2983-93. 2012
  3. ncbi A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women
    Kelly A Meckling
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
    Appl Physiol Nutr Metab 32:743-52. 2007
  4. doi Effect of the protein:carbohydrate ratio in hypoenergetic diets on metabolic syndrome risk factors in exercising overweight and obese women
    Dawn D Campbell
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Br J Nutr 108:1658-71. 2012
  5. doi Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkappaB in differentiating NB4 leukemia cells
    Wenqing Wu
    Department of Human Health, University of Guelph, Guelph, Ontario, Canada
    Exp Cell Res 316:1101-8. 2010
  6. ncbi Effects of a hypocaloric, low-carbohydrate diet on weight loss, blood lipids, blood pressure, glucose tolerance, and body composition in free-living overweight women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON NIG 2W1, Canada
    Can J Physiol Pharmacol 80:1095-105. 2002
  7. ncbi Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Leuk Lymphoma 48:1816-27. 2007
  8. ncbi Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Leuk Res 31:955-68. 2007
  9. doi Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells
    Cynthia L Richard
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1
    Exp Cell Res 316:695-703. 2010
  10. pmc Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
    Ming C Cha
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    BMC Pharmacol 5:7. 2005

Collaborators

Detail Information

Publications12

  1. ncbi Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, N1G 2W1 Ontario, Canada
    J Clin Endocrinol Metab 89:2717-23. 2004
    ..These data suggest that energy restriction achieved by a very LC diet is equally effective as a LF diet strategy for weight loss and decreasing body fat in overweight and obese adults...
  2. doi In vitro antioxidant synergism and antagonism between food extracts can lead to similar activities in H2O2-induced cell death, caspase-3 and MMP-2 activities in H9c2 cells
    Sunan Wang
    Guelph Food Research Center, Agriculture and Agri Food Canada, Guelph, Ontario, Canada
    J Sci Food Agric 92:2983-93. 2012
    ..This in vitro study evaluated the relationship between the in vitro antioxidant capacity of mixtures and their bioactivity when cardiomyocytes (H9c2) were challenged with H(2)O(2)...
  3. ncbi A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women
    Kelly A Meckling
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
    Appl Physiol Nutr Metab 32:743-52. 2007
    ....
  4. doi Effect of the protein:carbohydrate ratio in hypoenergetic diets on metabolic syndrome risk factors in exercising overweight and obese women
    Dawn D Campbell
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Br J Nutr 108:1658-71. 2012
    ..A diet with a 1:2 protein:carbohydrate ratio promoted better improvements than either the LP or HP diets, and may be superior in reducing long-term chronic disease risk in this population...
  5. doi Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkappaB in differentiating NB4 leukemia cells
    Wenqing Wu
    Department of Human Health, University of Guelph, Guelph, Ontario, Canada
    Exp Cell Res 316:1101-8. 2010
    ..This suggests a role for 1,25D(3)-MARRS in the nucleus as a regulator of gene expression. Here it may also regulate the activity of NFkappaB and other factors with which it may be interacting...
  6. ncbi Effects of a hypocaloric, low-carbohydrate diet on weight loss, blood lipids, blood pressure, glucose tolerance, and body composition in free-living overweight women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON NIG 2W1, Canada
    Can J Physiol Pharmacol 80:1095-105. 2002
    ....
  7. ncbi Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Leuk Lymphoma 48:1816-27. 2007
    ..Expression of the unique guanosine-specific nucleoside transporter csg in NB4 cells may provide an opportunity to harness guanosine-mediated cell death in the treatment of APL and related malignancies while sparing normal cells...
  8. ncbi Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Leuk Res 31:955-68. 2007
    ....
  9. doi Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells
    Cynthia L Richard
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1
    Exp Cell Res 316:695-703. 2010
    ..Further research should examine the potential for pharmacological or natural agents that modify 1,25D3-MARRS expression or activity as anticancer agents...
  10. pmc Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
    Ming C Cha
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    BMC Pharmacol 5:7. 2005
    ..Here we investigate whether the omega-3 fatty acid docosahexaenoic acid (DHA) could selectively target araC toxicity toward colonic tumor cells while protecting the normal cells in vitro...
  11. doi Synergistic, additive, and antagonistic effects of food mixtures on total antioxidant capacities
    Sunan Wang
    Guelph Food Research Center, Agriculture and Agri Food Canada, Guelph, Ontario, Canada
    J Agric Food Chem 59:960-8. 2011
    ..Compositional changes did not seem to have occurred in the mixture. Results in this study suggest the importance of strategically selecting foods or diets to maximum synergisms as well as to minimum antagonisms in antioxidant activity...
  12. ncbi Fatty acids and exercise affect glucose transport but not tumour growth in F-344 rats
    Jennifer M Foley
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON
    Can J Appl Physiol 29:604-22. 2004
    ..High DHA diets may also increase oxidative damage in muscle through enhanced TBARM production...