Jianping Xu

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi request reprint Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario, L8S 4K1, Canada
    Microbiology 148:203-12. 2002
  2. pmc Evidence for mitotic recombination within the basidia of a hybrid cross of Cryptococcus neoformans
    Aaron A Vogan
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 8:e62790. 2013
  3. doi request reprint Mitochondrial recombination in natural populations of the button mushroom Agaricus bisporus
    Jianping Xu
    Laboratory for Conservation and Utilization of Bio Resources, Yunnan University, Kunming, PR China
    Fungal Genet Biol 55:92-7. 2013
  4. ncbi request reprint Divergence, hybridization, and recombination in the mitochondrial genome of the human pathogenic yeast Cryptococcus gattii
    Jianping Xu
    Department of Biology, and Institute of Infectious Disease Research, Michael G DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    Mol Ecol 18:2628-42. 2009
  5. ncbi request reprint Comparative gene genealogical analyses of strains of serotype AD identify recombination in populations of serotypes A and D in the human pathogenic yeast Cryptococcus neoformans
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    Microbiology 149:2147-54. 2003
  6. ncbi request reprint The prevalence and evolution of sex in microorganisms
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    Genome 47:775-80. 2004
  7. pmc Genotype-environment interactions of spontaneous mutations for vegetative fitness in the human pathogenic fungus Cryptococcus neoformans
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 168:1177-88. 2004
  8. pmc Cost of interacting with sexual partners in a facultative sexual microbe
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 171:1597-604. 2005
  9. ncbi request reprint Single nucleotide polymorphisms in the ectomycorrhizal mushroom Tricholoma matsutake
    Jianping Xu
    Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, People s Republic of China
    Microbiology 153:2002-12. 2007
  10. doi request reprint Recombination and genetic differentiation among natural populations of the ectomycorrhizal mushroom Tricholoma matsutake from southwestern China
    Jianping Xu
    Key Laboratory of Biodiversity and Biogeography, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650204, China
    Mol Ecol 17:1238-47. 2008

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario, L8S 4K1, Canada
    Microbiology 148:203-12. 2002
    ..The results demonstrate that the evolution of C. neoformans is continuing and dynamic...
  2. pmc Evidence for mitotic recombination within the basidia of a hybrid cross of Cryptococcus neoformans
    Aaron A Vogan
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 8:e62790. 2013
    ..The mitotic recombination likely includes both chromosomal loss and crossing over. This novel recombination process could play an important role in generating the genotypic and phenotypic diversities of this important human pathogen...
  3. doi request reprint Mitochondrial recombination in natural populations of the button mushroom Agaricus bisporus
    Jianping Xu
    Laboratory for Conservation and Utilization of Bio Resources, Yunnan University, Kunming, PR China
    Fungal Genet Biol 55:92-7. 2013
    ..We discuss the potential mechanisms that could have contributed to the observed mitochondrial recombination and to the differences in allelic associations among the geographic populations in this economically important mushroom...
  4. ncbi request reprint Divergence, hybridization, and recombination in the mitochondrial genome of the human pathogenic yeast Cryptococcus gattii
    Jianping Xu
    Department of Biology, and Institute of Infectious Disease Research, Michael G DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    Mol Ecol 18:2628-42. 2009
    ..Our analyses suggest historical mitochondrial genome divergence within C. gattii, but there is evidence for recent hybridization and recombination in the mitochondrial genome of this important human yeast pathogen...
  5. ncbi request reprint Comparative gene genealogical analyses of strains of serotype AD identify recombination in populations of serotypes A and D in the human pathogenic yeast Cryptococcus neoformans
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    Microbiology 149:2147-54. 2003
    ..The results suggest recombination in natural populations of both serotypes A and D...
  6. ncbi request reprint The prevalence and evolution of sex in microorganisms
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    Genome 47:775-80. 2004
    ..It is argued that microbes are excellent model organisms to explore the mechanisms responsible for the evolution of sex...
  7. pmc Genotype-environment interactions of spontaneous mutations for vegetative fitness in the human pathogenic fungus Cryptococcus neoformans
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 168:1177-88. 2004
    ..neoformans were consistent with laboratory experimental population analyses. This study calls into question our long-standing view that warm-blooded mammals were only occasional and accidental hosts of this human fungal pathogen...
  8. pmc Cost of interacting with sexual partners in a facultative sexual microbe
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 171:1597-604. 2005
    ..This cost must have been compensated for by the production of zygotes and sexual spores to allow the initial evolution and spread of sexual reproduction in eukaryotes...
  9. ncbi request reprint Single nucleotide polymorphisms in the ectomycorrhizal mushroom Tricholoma matsutake
    Jianping Xu
    Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, People s Republic of China
    Microbiology 153:2002-12. 2007
    ..The implications of these SNPs and haplotypes for our understanding of the genetics, population history, ecology and evolution of this important mushroom species are discussed...
  10. doi request reprint Recombination and genetic differentiation among natural populations of the ectomycorrhizal mushroom Tricholoma matsutake from southwestern China
    Jianping Xu
    Key Laboratory of Biodiversity and Biogeography, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650204, China
    Mol Ecol 17:1238-47. 2008
    ..We discuss the implications of our results to the ecology and resource management of this species...
  11. ncbi request reprint The inheritance of organelle genes and genomes: patterns and mechanisms
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, ON, Canada
    Genome 48:951-8. 2005
    ....
  12. ncbi request reprint Microbial ecology in the age of genomics and metagenomics: concepts, tools, and recent advances
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
    Mol Ecol 15:1713-31. 2006
    ..The integration of various levels of ecological analyses coupled to the application and further development of high throughput technologies are accelerating the pace of discovery in microbial ecology...
  13. ncbi request reprint Fundamentals of fungal molecular population genetic analyses
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
    Curr Issues Mol Biol 8:75-89. 2006
    ..These developments are bringing fungal population and evolutionary genetics into mainstream ecology and evolutionary biology...
  14. ncbi request reprint Extracting haplotypes from diploid organisms
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, L8S 4K1, Canada
    Curr Issues Mol Biol 8:113-22. 2006
    ..With increasing sophistication in both bioinformatics tools and high-throughput molecular techniques, haplotype analysis is becoming an integrated component in biomedical research...
  15. ncbi request reprint Quantitative variation of biofilms among strains in natural populations of Candida albicans
    Xiaogang Li
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada L8S 4K1
    Microbiology 149:353-62. 2003
    ..The results demonstrated that natural clones and clonal lineages of C. albicans exhibited extensive quantitative variation in biofilm formation...
  16. doi request reprint Molecular, developmental, and evolutionary genetic studies highlight rapid evolution of genes and genetic systems
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, ON, Canada
    Genome 53:848-52. 2010
    ..The combined molecular, developmental, and evolutionary genetic investigations presented at the meeting, especially those on model organisms, highlighted that genes and genetic systems can evolve very rapidly...
  17. pmc Estimating the spontaneous mutation rate of loss of sex in the human pathogenic fungus Cryptococcus neoformans
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 162:1157-67. 2002
    ..0172 and 0.0036, respectively. The results show that C. neoformans can be a highly attractive model for analyses of reproductive system evolution in fungi...
  18. ncbi request reprint Mitochondrial DNA polymorphisms in the human pathogenic fungus Cryptococcus neoformans
    Jianping Xu
    Department of Biology, LSB437, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
    Curr Genet 41:43-7. 2002
    ..These results were discussed in the context of recent findings regarding the origins of serotype AD strains and the observed uniparental mtDNA inheritance in laboratory crosses between strains of serotypes A and D...
  19. pmc Dynamic and heterogeneous mutations to fluconazole resistance in Cryptococcus neoformans
    J Xu
    Department of Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Antimicrob Agents Chemother 45:420-7. 2001
    ..These results suggest that dynamic and heterogeneous mutational processes are involved in generating fluconazole resistance in C. neoformans...
  20. ncbi request reprint Fine-scale genetic analyses reveal unexpected spatial-temporal heterogeneity in two natural populations of the commercial mushroom Agaricus bisporus
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1
    Microbiology 148:1253-62. 2002
    ..The results demonstrated spatial-temporal genetic heterogeneity of A. bisporus in natural populations...
  21. pmc Genetic analyses of a hybrid cross between serotypes A and D strains of the human pathogenic fungus Cryptococcus neoformans
    Sheng Sun
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 177:1475-86. 2007
    ..We discuss the implications of our results in our understanding of the speciation and evolution of the C. neoformans species complex...
  22. doi request reprint Prevalence of specific and phylogenetically closely related genotypes in the population of Candida albicans associated with genital candidiasis in China
    Shu Hua Ge
    State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
    Fungal Genet Biol 49:86-93. 2012
    ..The results suggest significant association of specific and genetically similar genotypes with genital infections in China...
  23. pmc Correlation between azole susceptibilities, genotypes, and ERG11 mutations in Candida albicans isolates associated with vulvovaginal candidiasis in China
    Shu Hua Ge
    Institute of Microbiology, Chinese Academy of Sciences, No 1 West Beichen Road, Chaoyang District, Beijing 100101, China
    Antimicrob Agents Chemother 54:3126-31. 2010
    ..The correlation between azole susceptibility and C. albicans genotype may be of potential therapeutic significance...
  24. ncbi request reprint Multiple gene genealogical analyses suggest divergence and recent clonal dispersal in the opportunistic human pathogen Candida guilliermondii
    Lisa Lan
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Microbiology 152:1539-49. 2006
    ..guilliermondii and C. fermentati. The multiple gene genealogical analyses conducted here revealed significant divergence and clonal dispersal in this important pathogenic yeast complex...
  25. doi request reprint Mitochondrial inheritance in haploid x non-haploid crosses in Cryptococcus neoformans
    Irina Skosireva
    Department of Biology, Institute of Infectious Disease Research, Michael G DeGroote School of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada
    Curr Genet 56:163-76. 2010
    ..Flow cytometry analysis revealed that meiotic progeny population of each cross was of mixed ploidy while the ploidy level of the selected fusants ranged from diploid to triploid...
  26. doi request reprint Torulaspora quercuum sp. nov. and Candida pseudohumilis sp. nov., novel yeasts from human and forest habitats
    Qi Ming Wang
    Systematic Mycology and Lichenology Laboratory, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    FEMS Yeast Res 9:1322-6. 2009
    ..nov. is proposed for strain XZ-281(T) (=AS 2.3956(T)=CBS 11404(T)) and a teleomorphic name Torulaspora quercuum sp. nov. is proposed for strain 17YF(T) (=AS 2.3768(T)=CBS 11403(T)) and the other three oral strains...
  27. doi request reprint Prevalent nosocomial clusters among causative agents for candidemia in Hamilton, Canada
    Harinad Maganti
    Department of Biology, McMaster University, Hamilton, ON, Canada
    Med Mycol 49:530-8. 2011
    ..Our results indicated that 33% of the patients with candidemia were infected by nosocomial clusters and suggested that measures should be taken in hospitals to prevent nosocomial acquisition of Candida infections...
  28. pmc Chromosomal rearrangements between serotype A and D strains in Cryptococcus neoformans
    Sheng Sun
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 4:e5524. 2009
    ..We discuss the implications of these results on the genome structure, ecology, and evolution of C. neoformans...
  29. pmc Genetic diversity of Dahongjun, the commercially important "Big Red Mushroom" from southern China
    Mochan Li
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 5:e10684. 2010
    ..Although ecologically and economically important, very little is known about this mushroom, including its diversity and population structure...
  30. doi request reprint Genetic diversity of the endemic gourmet mushroom Thelephora ganbajun from south-western China
    Tao Sha
    Laboratory for Conservation and Utilization of Bio Resources, Yunnan University, Kunming, PR China
    Microbiology 154:3460-8. 2008
    ..Our study revealed significant genetic divergence within Th. ganbajun and limited but detectable gene flow among geographical populations of this endemic ectomycorrhizal gourmet mushroom...
  31. doi request reprint Genome variation in the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti
    Hong Guo
    Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada
    Genome 52:862-75. 2009
    ..Interestingly, we observed positive correlations among the three replicons in the number of absent ORFs as well as the number of duplicated ORFs, consistent with coordinated gene gains and losses in this important bacterium in nature...
  32. doi request reprint Long-distance dispersal and recombination in environmental populations of Cryptococcus neoformans var. grubii from India
    Sanjay S Hiremath
    Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada
    Microbiology 154:1513-24. 2008
    ..Our results are consistent with the hypothesis of long-distance dispersal and recombination in environmental populations of this species in India...
  33. pmc Structure, gene flow, and recombination among geographic populations of a Russula virescens ally from Southwestern China
    Yang Cao
    Laboratory for Conservation and Utilization of Bio Resources, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, Yunnan, PR China
    PLoS ONE 8:e73174. 2013
    ..We discuss the implications of our results for understanding speciation, reproduction and conservation of this important biological resource. ..
  34. pmc Geographic distribution of mating type alleles of Cryptococcus neoformans in four areas of the United States
    Zhun Yan
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    J Clin Microbiol 40:965-72. 2002
    ..In addition, our result demonstrate that the sample from San Francisco had a significantly higher proportion of self-fertile strains than those from the other three areas...
  35. ncbi request reprint The mating type-specific homeodomain genes SXI1 alpha and SXI2a coordinately control uniparental mitochondrial inheritance in Cryptococcus neoformans
    Zhun Yan
    Department of Biology, McMaster University, Hamilton, ON, Canada, L8S 4K1
    Curr Genet 51:187-95. 2007
    ..Our results suggest that SXI1alpha and SXI2a coordinately control uniparental mitochondrial inheritance in C. neoformans...
  36. ncbi request reprint Multiple gene genealogical analyses reveal both common and distinct population genetic patterns among replicons in the nitrogen-fixing bacterium Sinorhizobium meliloti
    Sheng Sun
    Center for Environmental Genomics, Department of Biology, McMaster University, Hamilton, ON, Canada
    Microbiology 152:3245-59. 2006
    ..The results suggest both shared and distinct patterns of molecular evolution among the three replicons in the genomes of natural strains of S. meliloti...
  37. ncbi request reprint Environment factors can influence mitochondrial inheritance in the fungus Cryptococcus neoformans
    Zhun Yan
    Department of Biology, McMaster University, 1280 Main St W, Hamilton, Ont, Canada L8S 4K1
    Fungal Genet Biol 44:315-22. 2007
    ..Our results indicate a potentially adaptive role of biparental mtDNA inheritance and mtDNA recombination in certain environments in C. neoformans...
  38. pmc Mitochondria are inherited from the MATa parent in crosses of the basidiomycete fungus Cryptococcus neoformans
    Zhun Yan
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    Genetics 163:1315-25. 2003
    ..To our knowledge, this is the first demonstration that mating type controls mtDNA inheritance in fungi...
  39. pmc Evidence against barium in the mushroom Trogia venenata as a cause of sudden unexpected deaths in Yunnan, China
    Ying Zhang
    Laboratory for Conservation and Utilization of Bio Resources, Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, People s Republic of China
    Appl Environ Microbiol 78:8834-5. 2012
    ..We found that barium concentrations in T. venenata from Yunnan were low and comparable to other foods, inconsistent with barium concentrations in this mushroom as a significant contributor to these deaths...
  40. pmc DNA sequence analyses reveal abundant diversity, endemism and evidence for Asian origin of the porcini mushrooms
    Bang Feng
    Key Laboratory of Biodiversity and Biogeography, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, People s Republic of China
    PLoS ONE 7:e37567. 2012
    ..In contrast to the ancient dispersal of porcini in the strict sense in the Northern Hemisphere, the occurrence of B. reticulatus and B. edulis sensu lato in the Southern Hemisphere was probably due to recent human-mediated introductions...
  41. ncbi request reprint Geographical differences in human oral yeast flora
    Jianping Xu
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Clin Infect Dis 36:221-4. 2003
    ..Furthermore, Candida albicans, which is the predominant commensal and etiologic species of candidiasis in Europe and the Western Hemisphere, was relatively rare in China...
  42. ncbi request reprint Diversity of commensal yeasts within and among healthy hosts
    Angela P Kam
    Department of Biology, McMaster University, 1280 Main St West, Hamilton, L8S 4K1, Ontario, Canada
    Diagn Microbiol Infect Dis 43:19-28. 2002
    ..Our results indicate dynamic processes of yeast colonization, maintenance and evolution in healthy human hosts...
  43. pmc Isolation of Candida dubliniensis in an aboriginal community in Ontario, Canada
    Laura Montour
    Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    J Clin Microbiol 41:3423-6. 2003
    ..dubliniensis. Genotypic analysis identified polymorphisms in these strains and differences from two reference strains. Our results suggest that yeast populations from indigenous communities in North America may be unique...
  44. doi request reprint Fitness distribution and transgressive segregation across 40 environments in a hybrid progeny population of the human-pathogenic yeast Cryptococcus neoformans
    Morvarid Shahid
    Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada
    Genome 51:272-81. 2008
    ..Our study suggests that hybridization could play a significant role in the phenotypic evolution of this important human-pathogenic fungus...
  45. doi request reprint Divergence and dispersal of the nematode-trapping fungus Arthrobotrys oligospora from China
    Ying Zhang
    Laboratory for Conservation and Utilization of Bio Resources, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, Yunnan 650091, China Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario L8S 4K1, Canada
    Environ Microbiol Rep 3:763-73. 2011
    ..However, evidence for clonal reproduction was also found. We discuss the implications of our results to the conservation and biocontrol application of A. oligospora in agriculture and forestry...
  46. doi request reprint Two new unusual Leucoagaricus species (Agaricaceae) from tropical China with blue-green staining reactions
    Jun F Liang
    Key Laboratory of Biodiversity and Biogeography, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China
    Mycologia 102:1141-52. 2010
    ..flavovirens based on morphology and ITS sequence comparison. [corrected] A monophyletic group of four bluing species from Old World tropics is recovered but with poor measures of branch..
  47. pmc Novel DNA sequences from natural strains of the nitrogen-fixing symbiotic bacterium Sinorhizobium meliloti
    Hong Guo
    Center for Environmental Genomics, Department of Biology, McMaster University, 1280 Main St West, Hamilton, Ontario L8S 4K1, Canada
    Appl Environ Microbiol 71:7130-8. 2005
    ..Our results suggest potentially high rates of gene gain and loss in S. meliloti genomes...
  48. ncbi request reprint Candidemia in women with breast carcinoma treated with high-dose chemotherapy and autologous bone marrow transplantation
    Magnus Gottfredsson
    Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA
    Cancer 98:24-30. 2003
    ..No systemic antifungal prophylaxis was administered. The purpose of the current study was to evaluate the risk and long-term outcome of candidemia in this patient population...
  49. pmc Clonal and spontaneous origins of fluconazole resistance in Candida albicans
    J Xu
    Department of Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 38:1214-20. 2000
    ..The results suggest both clonal and spontaneous origins of fluconazole resistance in C. albicans...
  50. ncbi request reprint Clinical and tree hollow populations of human pathogenic yeast in Hamilton, Ontario, Canada are different
    Chris Carvalho
    Department of Biology, McMaster University, Hamilton, ON, Canada
    Mycoses 57:271-83. 2014
    ..Similarly, the yeast in humans and clinics do not appear to contribute to yeast in tree hollows. ..
  51. pmc Genetic diversity and recombination in natural populations of the nematode-trapping fungus Arthrobotrys oligospora from China
    Ying Zhang
    Laboratory for Conservation and Utilization of Bio Resources, and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University Kunming, Yunnan, 650091, China
    Ecol Evol 3:312-25. 2013
    ..We discussed the implications of our results to the conservation and biocontrol application of in agriculture and forestry...
  52. ncbi request reprint Point mutations in awdKpn which revert the prune/Killer of prune lethal interaction affect conserved residues that are involved in nucleoside diphosphate kinase substrate binding and catalysis
    L Timmons
    Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Biol Chem 270:23021-30. 1995
    ..These data suggest that an altered NDP kinase activity is involved in the mechanism underlying the conditional lethality of the awdKpn mutation...
  53. ncbi request reprint PCR-restriction fragment length polymorphism (RFLP) analyses reveal both extensive clonality and local genetic differences in Candida albicans
    J Xu
    Department of Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    Mol Ecol 8:59-73. 1999
    ..Possible mechanisms are presented to explain the observed patterns of genetic variation within and between C. albicans populations...
  54. pmc Lack of genetic differentiation between two geographically diverse samples of Candida albicans isolated from patients infected with human immunodeficiency virus
    J Xu
    Department of Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Bacteriol 181:1369-73. 1999
    ..The results indicated evidence of clonality both within and between these two geographically diverse samples. The samples are genetically very similar, with little evidence of genetic differentiation...
  55. pmc Species and genotypic diversities and similarities of pathogenic yeasts colonizing women
    J Xu
    Department of Microbiology, Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 37:3835-43. 1999
    ..Furthermore, a single host can be colonized with multiple species or multiple genotypes of the same species at the same or different body sites, indicating dynamic processes of yeast colonization on women...
  56. ncbi request reprint Development and characterization of a genetic linkage map of Cryptococcus neoformans var. neoformans using amplified fragment length polymorphisms and other markers
    A Forche
    Department of Biology, Duke University, Durham, North Carolina 27708, USA
    Fungal Genet Biol 31:189-203. 2000
    ..This linkage map should provide a framework for the ongoing genome sequencing project and will be a useful tool for studying the genetics and pathogenicity of this important medical yeast...
  57. ncbi request reprint Multiple gene genealogies reveal recent dispersion and hybridization in the human pathogenic fungus Cryptococcus neoformans
    J Xu
    Department of Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    Mol Ecol 9:1471-81. 2000
    ..Significant incongruences were observed among gene genealogies. The analyses indicated that the major lineages in C. neoformans diverged tens of millions of years ago but have undergone recent dispersion and hybridization...
  58. ncbi request reprint Abundant sequence variation around the mitochondrial origin of replication in the human opportunistic yeast pathogen Candida albicans from a tropical island in China
    Huamin Wang
    Department of Laboratory Medicine, Hainan Medical College, Haikou, Hainan, China
    Fungal Genet Biol 44:991-1001. 2007
    ..albicans mtDNA has a base substitution pattern different from its nuclear genome and that sequences from the mtOri region could enhance our understanding of C. albicans genome evolution and population structuring...
  59. pmc Comparative gene genealogies indicate that two clonal lineages of Cryptococcus gattii in British Columbia resemble strains from other geographical areas
    Sarah E Kidd
    School of Occupational and Environmental Hygiene, University of British Columbia, 301 2185 East Mall, Vancouver, British Columbia V6T 1Z4, Canada
    Eukaryot Cell 4:1629-38. 2005
    ..C. were also present among isolates from other areas of the world, indicating extensive strain dispersal. The nucleotide sequence diversity among isolates from B.C. was similar to that among isolates from other areas of the world...
  60. ncbi request reprint Oral yeast flora and its ITS sequence diversity among a large cohort of medical students in Hainan, China
    Huamin Wang
    Department of Laboratory Medicine, Hainan Medical College, Haikou, Hainan, China
    Mycopathologia 164:65-72. 2007
    ..Taken together, our analyses suggest that the oral yeast flora among host populations in China is highly heterogeneous and that there is a high ITS sequence diversity in the Hainan population of C. albicans...
  61. ncbi request reprint Molecular epidemiology of candidemia: evidence of clusters of smoldering nosocomial infections
    Lena Rós Asmundsdóttir
    Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Clin Infect Dis 47:e17-24. 2008
    ..The aim of this study was to investigate the molecular epidemiology of candidemia in a nationwide setting in Iceland during a 16-year period...
  62. ncbi request reprint SXI1alpha controls uniparental mitochondrial inheritance in Cryptococcus neoformans
    Zhun Yan
    Curr Biol 14:R743-4. 2004
  63. ncbi request reprint Distribution of Cryptococcus gattii and Cryptococcus neoformans in decayed trunk wood of Syzygium cumini trees in north-western India
    H S Randhawa
    Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India
    Med Mycol 44:623-30. 2006
    ..neoformans in north-western India. Attention is drawn to the likely health hazard posed by the environmental reservoirs of C. gattii and C. neoformans occurring in tree trunk hollows in proximity to human and animal habitations...
  64. ncbi request reprint A polymorphic glucocorticoid receptor in a mouse population may explain inherited altered stress response and increased anxiety-type behaviors
    Dongsheng Xu
    Department of Veterinary and Biomedical Science, University of Nebraska Lincoln, Lincoln, NE 68588 0665, USA
    FASEB J 20:2414-6. 2006
    ..These results suggest this GR polymorphism plays a role in complex mechanisms leading to lower corticosterone response to stress, and may also be associated with decreased locomotive and increased anxiety-type behaviors in mice...
  65. pmc The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas
    J Armando Casas-Mollano
    School of Biological Sciences and Plant Science Initiative and Department of Chemistry, University of Nebraska, Lincoln, NE 68588 0666, USA
    Proc Natl Acad Sci U S A 105:6486-91. 2008
    ..Our results suggest that H3T3ph and H3K4me1 function as reinforcing epigenetic marks for the silencing of euchromatic loci in Chlamydomonas...
  66. ncbi request reprint A simple predictive model of prolonged intensive care unit stay after surgery for acquired heart valve disease
    Jianping Xu
    Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Bei Jing, China
    J Heart Valve Dis 16:109-15. 2007
    ..The study aim was to construct a simple model (the Fuwai risk score) to predict prolonged intensive care unit (ICU) stay after surgery to treat acquired heart valve disease...
  67. pmc Monomethyl histone H3 lysine 4 as an epigenetic mark for silenced euchromatin in Chlamydomonas
    Karin van Dijk
    Department of Plant Pathology and Plant Science Initiative, University of Nebraska, Lincoln, Nebraska 68588 0666, USA
    Plant Cell 17:2439-53. 2005
    ..Together, our results suggest functional differentiation between dimethyl H3K4 and monomethyl H3K4, with the latter operating as an epigenetic mark for repressed euchromatin...
  68. ncbi request reprint Encoded and enzyme-activated nanolithography of gold and magnetic nanoparticles on silicon
    Bernhard Basnar
    Institute of Chemistry and the Center of Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Langmuir 23:2293-6. 2007
    ..The different NPs are linked to the patterns by the formation of complexes between the boronic acid residues or Fe3+ ions and the catechol ligands...
  69. ncbi request reprint Generation of rye (Secale cereale L.) plants with low transgene copy number after biolistic gene transfer and production of instantly marker-free transgenic rye
    Juan Carlos Popelka
    Institut für Pflanzengenetik und Kulturpflanzenforschung Gatersleben, Corrensstrasse 3, 06466 Gatersleben, Germany
    Transgenic Res 12:587-96. 2003
    ....