Research Topics
| Jim R WrightSummaryAffiliation: McMaster University Country: Canada Publications
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Detail Information
Publications
Almost famous: E. Clark Noble, the common thread in the discovery of insulin and vinblastineJames R Wright
Department of Pathology, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
CMAJ 167:1391-6. 2002..Although one might expect that a physician involved in 2 of Canada's most important medical discoveries during the 20th century must be famous, such was not Clark Noble's fate. He died without so much as an obituary in CMAJ...
Why cancer patients enter randomized clinical trials: exploring the factors that influence their decisionJames R Wright
Juravinski Cancer Centre, 699 Concession St, Hamilton, Ontario L8V 5C2
J Clin Oncol 22:4312-8. 2004..The present study was undertaken to identify the independent predictors of a cancer patient's decision to enter a randomized clinical trial...
Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemiaJames R Wright
Juravinski Cancer Center at Hamilton Health Sciences, Hamilton, Ontario, Canada
J Clin Oncol 25:1027-32. 2007..We designed a trial to investigate the effects of epoetin alfa therapy on the QOL of anemic patients with advanced non-small-cell carcinoma of the lung (NSCLC)...
Factors that influence the recruitment of patients to Phase III studies in oncology: the perspective of the clinical research associateJames R Wright
Hamilton Regional Cancer Centre, Cancer Care Ontario, Hamilton, Ontario, Canada
Cancer 95:1584-91. 2002..The current study was initiated to explore the factors that influence the decision of patients with cancer regarding clinical trial entry, specifically from the perspective of the CRA...
Digital necrosis associated with squamous cell carcinoma of the tonsilJim R Wright
Department of Radiation Oncology, Hamilton Regional Cancer Centre, Cancer Care Ontario, 699 Concession St, Hamilton, Ontario, Canada L8V 5C2
Head Neck 24:1019-21. 2002..Digital necrosis is an uncommon paraneoplastic syndrome. Fewer than 50 cases have been sporadically reported through the literature over the last 30 years...
Radiation induced mucositis: co-ordinating a research agendaJ R Wright
Department of Radiation Oncology, Hamilton Regional Cancer Center, Cancer Care Ontario, Hamilton, Ontario, Canada
Clin Oncol (R Coll Radiol) 15:473-7. 2003..Any additional information needed before the launch of any potential trial was also requested. In this paper, we will review and summarise the outcomes from the radiation-induced mucositis sessions...
Estimating per patient funding for cancer clinical trials: an Ontario based surveyJames R Wright
Juravinski Cancer Center, Hamilton Health Sciences, 699 Concession St, Hamilton, Ontario, Canada, L8V 5C2
Contemp Clin Trials 26:421-9. 2005..These issues are likely not unique to oncology...
Phase III Trial of an emulsion containing trolamine for the prevention of radiation dermatitis in patients with advanced squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Trial 99-13Elizabeth A Elliott
Juravinski Cancer Centre at Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
J Clin Oncol 24:2092-7. 2006..This multicentered phase III trial was designed to compare an emulsion containing trolamine against the usual supportive care within each participating institution for patients with head and neck cancer undergoing radiation therapy...
Pilot study of the quality initiative in rectal cancer strategyMarko I Simunovic
Department of Surgery, McMaster University, Hamilton, Ontario, Canada
Dis Colon Rectum 47:1594-8. 2004..We developed the surgeon-directed, multipronged Quality Initiative in Rectal Cancer strategy to encourage surgeons to use total mesorectal excision techniques...
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factorsEdward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
Lancet Oncol 7:141-8. 2006..Enrolling participants onto clinical trials of cancer presents an important challenge. We aimed to identify the concerns of patients with cancer about, and the barriers to, participation in clinical trials...
The importance of reporting patient recruitment details in phase III trialsJames R Wright
Juravinski Cancer Centre at Hamilton Health Sciences, and Department of Medicine, McMaster University, Hamilton, ON, Canada
J Clin Oncol 24:843-5. 2006
From ugly fish to conquer death: J J R Macleod's fish insulin research, 1922-24James R Wright
Department of Pathology, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
Lancet 359:1238-42. 2002..As a result of this breakthrough, the scales began to tip heavily in favour of livestock insulin. Nevertheless, research on commercial production of fish insulin continued for another 18 months but was finally abandoned...
Public consultation on xenotransplantationJames R Wright
Departments of Pathology, Surgery, and Biomedical Engineering, Dalhousie University Faculty of Medicine and IWK Health Centre, 5850 University Avenue, Halifax, Nova Scotia B3H 1V7, Canada
Transplantation 78:1112-3. 2004..I offer an alternative analysis of the data collected during the consultation, which results in different conclusions...
Researching the cost of researchJames R Wright
J Clin Oncol 21:4081-2. 2003
Commentary on the Canadian public consultation on xenotransplantationJames R Wright
Xenotransplantation 10:475-6. 2003
Association between Breus' mole and partial hydatidiform mole: chance or can hydropic villi precipitate placental massive subchorionic thrombosis?Dae Tong Kim
Department of Pathology, IWK Grace Health Centre, Halifax, Nova Scotia, Canada
Pediatr Pathol Mol Med 21:451-9. 2002..Thus, we suggest that obstruction of maternal venous return by hydropic villi may have played a contributory role in some of these other reported cases...
Alternative interpretations of the same data: flaws in the process of consulting the Canadian public about xenotransplantation issuesJames R Wright
Department of Pathology, IWK Health Centre, Dalhousie University, Halifax, NS
CMAJ 167:40-2. 2002
Association of phosphorylated epidermal growth factor receptor with survival in patients with locally advanced non-small cell lung cancer treated with radiotherapyTheodoros Tsakiridis
Department of Oncology, McMaster University, McMaster University, Hamilton, Ontario, Canada
J Thorac Oncol 3:716-22. 2008..The epidermal growth factor receptor (EGFR) and its downstream effector kinases are thought to have important roles in lung cancer cell proliferation and response to treatment...
