Timothy Whelan

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi The Quality Initiative in Rectal Cancer (QIRC) trial: study protocol of a cluster randomized controlled trial in surgery
    Marko Simunovic
    Department of Surgery, McMaster University, St, Joseph s Healthcare, G838 50 Charlton Ave, East, Hamilton, Ontario, L8N 4A6, Canada
    BMC Surg 8:4. 2008
  2. ncbi Radiotherapy fractionation for the palliation of uncomplicated painful bone metastases - an evidence-based practice guideline
    Jackson Sai Yiu Wu
    Department of Radiation Oncology, Tom Baker Cancer Centre, Calgary, Alberta, Canada
    BMC Cancer 4:71. 2004
  3. ncbi Effect of a decision aid on knowledge and treatment decision making for breast cancer surgery: a randomized trial
    Timothy Whelan
    Department of Medicine, McMaster University, Hamilton Health Sciences, Hamilton, Ontario, Canada
    JAMA 292:435-41. 2004
  4. ncbi Physician/patient decision aids for adjuvant therapy
    Timothy J Whelan
    Juravinski Cancer Centre, 699 Concession St, Room 3-62, Hamilton, Ontario, L8V 5C2 Canada
    J Clin Oncol 23:1627-30. 2005
  5. ncbi Use of conventional radiation therapy as part of breast-conserving treatment
    Timothy J Whelan
    Department of Medicine, McMaster University, Hamilton, Ontario, Candada
    J Clin Oncol 23:1718-25. 2005
  6. ncbi Assessment of quality of life in MA.17: a randomized, placebo-controlled trial of letrozole after 5 years of tamoxifen in postmenopausal women
    Timothy J Whelan
    McMaster University, Hamilton, Canada
    J Clin Oncol 23:6931-40. 2005
  7. ncbi Helping patients make informed choices: a randomized trial of a decision aid for adjuvant chemotherapy in lymph node-negative breast cancer
    Timothy Whelan
    Cancer Care Ontario CCO, Hamilton Regional Cancer Centre, and Supportive Cancer Care Research Unit, McMaster University, Hamilton, Ontario, Canada
    J Natl Cancer Inst 95:581-7. 2003
  8. ncbi Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer
    Timothy Whelan
    T Whelan, M Levine, McMaster University, and Cancer Care Ontario CCO Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
    J Natl Cancer Inst 94:1143-50. 2002
  9. ncbi Does locoregional radiation therapy improve survival in breast cancer? A meta-analysis
    T J Whelan
    Departments of Medicine, Clinical Epidemiology, and Biostatistics, McMaster University, and Cancer Care Ontario, Hamilton Regional Cancer Centre, Hamilton, ON, Canada
    J Clin Oncol 18:1220-9. 2000
  10. ncbi Influence of hospital characteristics on operative death and survival of patients after major cancer surgery in Ontario
    Marko Simunovic
    Department of Surgery, Faculty of Health Sciences, McMaster University, The Juravinski Cancer Centre, Hamilton, ON
    Can J Surg 49:251-8. 2006

Detail Information

Publications32

  1. ncbi The Quality Initiative in Rectal Cancer (QIRC) trial: study protocol of a cluster randomized controlled trial in surgery
    Marko Simunovic
    Department of Surgery, McMaster University, St, Joseph s Healthcare, G838 50 Charlton Ave, East, Hamilton, Ontario, L8N 4A6, Canada
    BMC Surg 8:4. 2008
    ..The strategy is designed to optimize the use of total mesorectal excision techniques...
  2. ncbi Radiotherapy fractionation for the palliation of uncomplicated painful bone metastases - an evidence-based practice guideline
    Jackson Sai Yiu Wu
    Department of Radiation Oncology, Tom Baker Cancer Centre, Calgary, Alberta, Canada
    BMC Cancer 4:71. 2004
    ..This practice guideline was developed to provide recommendations to clinicians in Ontario on the preferred standard radiotherapy fractionation schedule for the treatment of painful bone metastases...
  3. ncbi Effect of a decision aid on knowledge and treatment decision making for breast cancer surgery: a randomized trial
    Timothy Whelan
    Department of Medicine, McMaster University, Hamilton Health Sciences, Hamilton, Ontario, Canada
    JAMA 292:435-41. 2004
    ..Consequently, the choice of treatment should be based on a patient's preferences...
  4. ncbi Physician/patient decision aids for adjuvant therapy
    Timothy J Whelan
    Juravinski Cancer Centre, 699 Concession St, Room 3-62, Hamilton, Ontario, L8V 5C2 Canada
    J Clin Oncol 23:1627-30. 2005
  5. ncbi Use of conventional radiation therapy as part of breast-conserving treatment
    Timothy J Whelan
    Department of Medicine, McMaster University, Hamilton, Ontario, Candada
    J Clin Oncol 23:1718-25. 2005
  6. ncbi Assessment of quality of life in MA.17: a randomized, placebo-controlled trial of letrozole after 5 years of tamoxifen in postmenopausal women
    Timothy J Whelan
    McMaster University, Hamilton, Canada
    J Clin Oncol 23:6931-40. 2005
    ..To evaluate the impact of letrozole compared with placebo after adjuvant tamoxifen on quality of life (QOL) in the MA.17 trial...
  7. ncbi Helping patients make informed choices: a randomized trial of a decision aid for adjuvant chemotherapy in lymph node-negative breast cancer
    Timothy Whelan
    Cancer Care Ontario CCO, Hamilton Regional Cancer Centre, and Supportive Cancer Care Research Unit, McMaster University, Hamilton, Ontario, Canada
    J Natl Cancer Inst 95:581-7. 2003
    ..We determined whether adding the Decision Board to the medical consultation improved patient knowledge and satisfaction compared with the medical consultation alone...
  8. ncbi Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer
    Timothy Whelan
    T Whelan, M Levine, McMaster University, and Cancer Care Ontario CCO Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
    J Natl Cancer Inst 94:1143-50. 2002
    ....
  9. ncbi Does locoregional radiation therapy improve survival in breast cancer? A meta-analysis
    T J Whelan
    Departments of Medicine, Clinical Epidemiology, and Biostatistics, McMaster University, and Cancer Care Ontario, Hamilton Regional Cancer Centre, Hamilton, ON, Canada
    J Clin Oncol 18:1220-9. 2000
    ..A systematic review of randomized trials that examine the effectiveness of locoregional radiation therapy in patients treated by definitive surgery and adjuvant systemic therapy was conducted...
  10. ncbi Influence of hospital characteristics on operative death and survival of patients after major cancer surgery in Ontario
    Marko Simunovic
    Department of Surgery, Faculty of Health Sciences, McMaster University, The Juravinski Cancer Centre, Hamilton, ON
    Can J Surg 49:251-8. 2006
    ..Therefore, we chose to study these relationships using data from patients treated in Ontario hospitals...
  11. ncbi Clinical practice guidelines for the care and treatment of breast cancer: breast radiotherapy after breast-conserving surgery (summary of the 2003 update)
    Timothy Whelan
    Cancer Care Ontario Hamilton Regional Cancer Centre and Department of Medicine, McMaster University, Hamilton, ON
    CMAJ 168:437-9. 2003
  12. ncbi Lymphedema in women with breast cancer: characteristics of patients screened for a randomized trial
    Ian S Dayes
    Department of Oncology, McMaster University, Hamilton, Ontario, Canada
    Breast Cancer Res Treat 110:337-42. 2008
    ..In two centres, patients presenting to lymphedema clinic were screened for eligibility to understand the accrual process and help define the patient population...
  13. ncbi Using administrative databases to measure waiting times for patients undergoing major cancer surgery in Ontario, 1993-2000
    Marko Simunovic
    Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario
    Can J Surg 48:137-42. 2005
    ..To determine how long patients in Ontario waited for major breast, colorectal, lung or prostate cancer surgery in the years 1993-2000...
  14. ncbi The impact of specialized oncology nursing on patient supportive care outcomes
    Jonathan Sussman
    Supportive Cancer Care Research Unit, Juravinski Cancer Centre, Hamilton, ON, Canada
    J Psychosoc Oncol 29:286-307. 2011
    ..The results of this study are important in supporting the design and development of controlled trials to examine provider roles in the coordination of supportive cancer care...
  15. ncbi Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases
    Jackson Sai Yiu Wu
    Division of Radiation Oncology, Hamilton Regional Cancer Centre, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Int J Radiat Oncol Biol Phys 55:594-605. 2003
    ..To compare pain relief among various dose-fractionation schedules of localized radiotherapy (RT) in the treatment of painful bone metastases...
  16. ncbi The difference between study recommendations, stated policy, and actual practice in a clinical trial
    J R Goffin
    National Cancer Institute of Canada, Clinical Trials Group, Kingston, Ontario, Canada
    Ann Oncol 15:1267-73. 2004
    ..We determined whether physicians involved in a clinical trial adhere to the study recommendations or the stated policy of their treatment centre with respect to the administration of boost radiation after breast conserving surgery...
  17. ncbi Job stress and job satisfaction of cancer care workers
    Eva Grunfeld
    Ottawa Regional Cancer Centre, Ottawa Health Research Institute, Ottawa, Ontario Canada K1H 1C4
    Psychooncology 14:61-9. 2005
    ..There is an increasing demand for oncology care as a result of a number of trends. In combination with ongoing changes to the health-care system, these trends have an impact on the workplace environment of systemic therapy personnel...
  18. ncbi Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17
    Hyman B Muss
    University of Vermont College of Medicine, 1 South Prospect St, Saint Joseph 3400, Burlington, VT 05401, USA
    J Clin Oncol 26:1956-64. 2008
    ..Breast cancer incidence increases with age and more than 1,300 women age 70 years or older were enrolled onto MA.17, making it ideal to explore the benefits, toxicities, and quality of life (QOL) impact of letrozole on older women...
  19. ncbi American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for women with hormone receptor-positive breast cancer: status report 2002
    Eric P Winer
    Health Services Research Department, American Society of Clinical Oncology, 1900 Duke Street, Suite 200, Alexandria, VA 22314, USA
    J Clin Oncol 20:3317-27. 2002
    ..POTENTIAL INTERVENTIONS: Anastrozole, letrozole, and exemestane...
  20. ncbi Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia
    James R Wright
    Juravinski Cancer Center at Hamilton Health Sciences, Hamilton, Ontario, Canada
    J Clin Oncol 25:1027-32. 2007
    ..We designed a trial to investigate the effects of epoetin alfa therapy on the QOL of anemic patients with advanced non-small-cell carcinoma of the lung (NSCLC)...
  21. ncbi American Society of Clinical Oncology technology assessment working group update: use of aromatase inhibitors in the adjuvant setting
    Eric P Winer
    American Society of Clinical Oncology, Alexandria, VA 22314, USA
    J Clin Oncol 21:2597-9. 2003
  22. ncbi Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer
    Lori J Pierce
    Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
    J Clin Oncol 24:2437-43. 2006
    ..We compared the outcome of breast-conserving surgery and radiotherapy in BRCA1/2 mutation carriers with breast cancer versus that of matched sporadic controls...
  23. ncbi Managing patients on endocrine therapy: focus on quality-of-life issues
    Timothy J Whelan
    McMaster University, Hamilton, Ontario, Canada
    Clin Cancer Res 12:1056s-1060s. 2006
    ..However, clinical benefits of these agents are generally achieved without major detrimental effect on overall QOL...
  24. ncbi A clinical trial of breast radiation therapy versus breast plus regional radiation therapy in early-stage breast cancer: the MA20 trial
    Ivo A Olivotto
    Radiation Oncology, British Columbia Cancer Agency and University of British Columbia, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC V8R 6V5, Canada
    Clin Breast Cancer 4:361-3. 2003
  25. ncbi In regard to Fortin et al., Int J Radiat Oncol Biol Phys 2003;56:1013-1022
    Ivo A Olivotto
    Int J Radiat Oncol Biol Phys 58:1317-8; author reply 1318. 2004
  26. ncbi Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy
    Pauline T Truong
    BC Cancer Agency-Vancouver Island Centre
    CMAJ 170:1263-73. 2004
    ..The final document was approved by the steering committee. SPONSOR: The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer was convened by Health Canada. COMPLETION DATE: November 2003...
  27. ncbi Why cancer patients enter randomized clinical trials: exploring the factors that influence their decision
    James R Wright
    Juravinski Cancer Centre, 699 Concession St, Hamilton, Ontario L8V 5C2
    J Clin Oncol 22:4312-8. 2004
    ..The present study was undertaken to identify the independent predictors of a cancer patient's decision to enter a randomized clinical trial...
  28. ncbi American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: status report 2004
    Eric P Winer
    Dana Farber Cancer Institute, 44 Binney St, D1210, Boston, MA 02115, USA
    J Clin Oncol 23:619-29. 2005
    ..To update the 2003 American Society of Clinical Oncology technology assessment on adjuvant use of aromatase inhibitors...
  29. ncbi The Initial Health Assessment: an intervention to identify the supportive care needs of cancer patients
    Dauna L Crooks
    School of Nursing, McMaster University, Hamilton, ON, Canada
    Support Care Cancer 12:19-24. 2004
    ..CONCLUSIONS: The IHA improved documentation of supportive care needs and resources. There is still room for improvement...
  30. ncbi The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma
    May N Tsao
    The American Society for Therapeutic Radiology and Oncology, Fairfax, VA 22033, USA
    Int J Radiat Oncol Biol Phys 63:47-55. 2005
    ..There is also insufficient evidence regarding the benefits/harms in the use of stereotactic fractionated radiation therapy for patients with newly diagnosed or progressive/recurrent malignant glioma...
  31. ncbi The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastases
    Minesh P Mehta
    The American Society for Therapeutic Radiology and Oncology, Fairfax, VA 22033, USA
    Int J Radiat Oncol Biol Phys 63:37-46. 2005
    ..There is insufficient evidence as to the clinical benefit/risks radiosurgery used in the setting of recurrent or progressive brain metastases, although radiographic responses are well-documented...
  32. ncbi Clinical experience using hypofractionated radiation schedules in breast cancer
    Timothy J Whelan
    Department of Oncology, McMaster University, Hamilton, Ontario, Canada Juravinski Cancer Centre, Hamilton, Ontario, Canada
    Semin Radiat Oncol 18:257-64. 2008
    ..Early cohort studies report good local control and acceptable morbidity. Randomized trials are now underway to compare this approach to conventional whole-breast irradiation...