Research Topics
| Kathryn WebertSummaryAffiliation: McMaster University Country: Canada Publications
| Collaborators
|
Detail Information
Publications
A new tool to assess bleeding severity in patients with chemotherapy-induced thrombocytopeniaKathryn E Webert
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Transfusion 52:2466-74; quiz 2465. 2012..The aim of this study was to develop a simple, valid, and reliable measurement tool to categorize the severity of bleeding in patients with chemotherapy-induced thrombocytopenia (CIT)...- Low prevalence of inhibitor antibodies in the Canadian haemophilia populationK E Webert
Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Haemophilia 18:e254-9. 2012..The classification system used in this study was easy for clinics to apply and was important in defining the population with inhibitors... 
Proceedings of a Consensus Conference: pathogen inactivation-making decisions about new technologiesKathryn E Webert
Medical, Scientific, and Research Affairs, Canadian Blood Services, Hamilton, Edmonton and Toronto, Canada
Transfus Med Rev 22:1-34. 2008..These proceedings are provided to make available to the transfusion medicine community the considerable amount of important information presented at this consensus conference...- A multicenter pilot-randomized controlled trial of the feasibility of an augmented red blood cell transfusion strategy for patients treated with induction chemotherapy for acute leukemia or stem cell transplantationKathryn E Webert
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Transfusion 48:81-91. 2008..Anemia may be an important factor contributing to an increased risk of bleeding, particularly in patients with thrombocytopenia... - Randomization in clinical trialsKathryn E Webert
Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
Transfusion 47:1753-4. 2007 - Utilization of recombinant activated factor VII in southern Ontario in 85 patients with and without haemophiliaK E Webert
Division of Hematology, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
Haemophilia 13:518-26. 2007..The tracking system used in this study is a valuable tool to describe ongoing utilization patterns of rFVIIa... - Treatment allocation in clinical trialsKathryn E Webert
Department of Medicine, McMaster University, and Canadian Blood Services, Hamilton, Ontario, Canada
Transfusion 47:2187-8. 2007 - A study of the agreement between patient self-assessment and study personnel assessment of bleeding symptomsKathryn E Webert
McMaster University, Hamilton, Ontario, Canada
Transfusion 46:1926-33. 2006..These assessments are commonly performed by study personnel and can be time-consuming. The purpose of this study was to assess whether patients were able to reliably assess their bleeding status on a daily basis... - The risk of bleeding in thrombocytopenic patients with acute myeloid leukemiaKathryn Webert
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Haematologica 91:1530-7. 2006..Patients with acute myeloid leukemia are at risk of bleeding. The risk factors for different severities of bleeding are poorly studied... - A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpuraKathryn E Webert
Department of Medicine, McMaster University, Rm HSC 3N43, 1200 Main St W, Hamilton, ON, Canada L8N 3Z5
Blood 102:4306-11. 2003..6%) required treatment for hemostatic impairment. Two fetal deaths occurred. One was caused by hemorrhage. ITP in pregnancy carries a low risk, but mothers and infants may require therapy to raise their platelet counts... - A randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopeniaNancy M Heddle
Department of Medicine, McMaster University, Hamilton, ON, Canada
Blood 113:1564-73. 2009..Whether this finding was due to chance or represents a real difference requires further investigation. These clinical studies are registered on (http://www.clinicaltrials.gov) as NCT00420914... 
Do expert assessments converge? An exploratory case study of evaluating and managing a blood supply riskJohn Eyles
School of Geography and Earth Sciences, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada
BMC Public Health 11:666. 2011..It also describes the context of publicly funded blood transfusion in Canada and the withdrawal event that is the basis of this study...- A policy informing qualitative study to improve the process of blood product recalls and withdrawalsNancy M Heddle
Departments of Medicine and the School of Geography, and Earth Science, McMaster University, Hamilton, Ontario, Canada
Transfusion 48:2585-95. 2008..With the use of qualitative techniques and a modified grounded theory approach, the current process was mapped, issues were identified, and recommendations to improve the system were developed... - An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet countsCatherine P M Hayward
McMaster University and the Hamilton Regional Laboratory Medicine Program, Hamilton, Ontario, Canada, L8N 3Z5
Thromb Haemost 100:134-45. 2008..The derived limits for thrombocytopenic samples provide guidance for evaluating thrombocytopenic platelet function disorders, including which agonists to test, based on the sample platelet count... - Consequences of transfusion of platelet antibody: a case report and literature reviewKaterina Pavenski
Department of Medicine, and the Department of Pathology and Laboratory Medicine, McMaster University, Hamilton, Ontario, Canada
Transfusion 48:1981-9. 2008..Passive transfer of platelet (PLT) antibody by blood transfusion can lead to severe thrombocytopenia, bleeding, and an acute transfusion reaction... - Comparing the efficacy and safety of apheresis and whole blood-derived platelet transfusions: a systematic reviewNancy M Heddle
The Department of Medicine and the Department of Molecular Medicine and Pathology, McMaster University, Hamilton, Ontario, Canada
Transfusion 48:1447-58. 2008.... - Factors affecting the frequency of red blood cell outdates: an approach to establish benchmarking targetsNancy M Heddle
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Transfusion 49:219-26. 2009..In this study, a provincial database of red blood cell (RBC) product inventory/disposition in hospitals was analyzed to identify factors that affected RBC outdates and to systematically establish optimal target levels for RBC outdates... - Understanding the meaning of permanent deferral for blood donorsSusan Whittaker
Department of Medicine and the Department of Nursing, McMaster University, Hamilton, Ontario, Canada
Transfusion 48:64-72. 2008..The purpose of this study was to explore the permanent deferral experience from the donor's perspective... - Proceedings of a consensus conference: the screening of blood donors for variant CJDMorris A Blajchman
Canadian Blood Services, Hamilton, Ontario, Canada
Transfus Med Rev 18:73-92. 2004..This contentious issue is of potential considerable importance to transfusion medicine personnel worldwide, as well as to future recipients of allogeneic blood components... - Methodologic issues in the use of bleeding as an outcome in transfusion medicine studiesNancy M Heddle
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Transfusion 43:742-52. 2003.... - Bleeding during critical illness: a prospective cohort study using a new measurement toolDonald M Arnold
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Clin Invest Med 30:E93-102. 2007..To estimate the incidence, severity, duration and consequences of bleeding during critical illness, and to test the performance characteristics of a new bleeding assessment tool... - Proceedings of a consensus conference: blood-borne HIV and hepatitis-optimizing the donor selection processJo Anne Chiavetta
Canadian Blood Services, HEMA QUEBEC, Canada
Transfus Med Rev 17:1-30. 2003.... - Transfusion-related acute lung injuryKathryn E Webert
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Transfus Med Rev 17:252-62. 2003..In this report, what is known about TRALI is summarized and some of the areas in which knowledge and/or consensus are currently lacking are identified... - Proceedings of a consensus conference: towards an understanding of TRALIMindy Goldman
Canadian Blood Services, Medical, Scientific and Research Affairs, Ottawa, Ontario K1G 4J5, Canada
Transfus Med Rev 19:2-31. 2005.... - Severe hemolytic anemia post-renal transplantation produced by donor anti-D passenger lymphocytes: case report and literature reviewCraig D Ainsworth
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Transfus Med Rev 23:155-9. 2009..Passenger lymphocyte syndrome-associated hemolysis is occasionally severe as in our case, but can be effectively treated with compatible RBC transfusions... - Transfusion-related acute lung injuryKathryn E Webert
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Curr Opin Hematol 12:480-7. 2005..SUMMARY: In this report, what is known about transfusion-related acute lung injury is summarized with particular emphasis on recent studies. Some of the areas in which knowledge and/or consensus are currently lacking are identified... - Randomized trials in patients with blunt and penetrating traumaKathryn E Webert
J Trauma 60:242-3; author reply 243-4. 2006 - Hypotensive transfusion reactions can occur with blood products that are leukoreduced before storageDonald M Arnold
Canadian Blood Services, Ontario, Canada
Transfusion 44:1361-6. 2004..CONCLUSION: Hypotensive reactions can occur with blood products that are LR before storage and non-LR ANH. An inherent defect in the metabolism of kinins may be a risk factor for the development of hypotensive transfusion reactions... - On-label versus off-label use of recombinant activated factor VII: a comprehensive review of use in two Canadian centersManuel D Carcao
Division of Hematology Oncology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada
Semin Hematol 45:S68-71. 2008..It is important to be aware of the increasing use of rFVIIa in off-label indications...