H Szechtman

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. pmc Where the imaginal appears real: a positron emission tomography study of auditory hallucinations
    H Szechtman
    Department of Biomedical Sciences, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Proc Natl Acad Sci U S A 95:1956-60. 1998
  2. ncbi request reprint Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD)
    H Szechtman
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Behav Neurosci 112:1475-85. 1998
  3. pmc Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control
    H Szechtman
    Dept of Psychiatry and Behavioural Neurosciences, McMaster University, Canada
    BMC Neurosci 2:4. 2001
  4. ncbi request reprint Increased TUNEL staining in brains of autoimmune Fas-deficient mice
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, HSC 4N77A, 1200 Main Street, Hamilton, Ontario, Canada
    J Neuroimmunol 104:147-54. 2000
  5. ncbi request reprint Immunosuppression prevents neuronal atrophy in lupus-prone mice: evidence for brain damage induced by autoimmune disease?
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada
    J Neuroimmunol 111:93-101. 2000
  6. ncbi request reprint Reduced corticotropin-releasing factor and enhanced vasopressin gene expression in brains of mice with autoimmunity-induced behavioral dysfunction
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Neuroimmunol 96:80-91. 1999
  7. ncbi request reprint Progressive atrophy of pyramidal neuron dendrites in autoimmune MRL-lpr mice
    B Sakic
    Department of Psychiatry, McMaster University, Hamilton, Ontario, Canada
    J Neuroimmunol 87:162-70. 1998
  8. ncbi request reprint Behavioral effects of infection with IL-6 adenovector
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Brain Behav Immun 15:25-42. 2001
  9. ncbi request reprint Association of altered whole-body metabolism with locomotor sensitization induced by quinpirole
    D V Coscina
    Department of Psychology, University of Toronto, Ontario, Canada
    Physiol Behav 63:755-61. 1998
  10. ncbi request reprint Monoamine oxidase inhibitor-induced blockade of locomotor sensitization to quinpirole: role of striatal dopamine uptake inhibition
    K E Culver
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, L8N 3Z5, Ontario, Canada
    Neuropharmacology 43:385-93. 2002

Collaborators

Detail Information

Publications16

  1. pmc Where the imaginal appears real: a positron emission tomography study of auditory hallucinations
    H Szechtman
    Department of Biomedical Sciences, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Proc Natl Acad Sci U S A 95:1956-60. 1998
    ..Inappropriate activation of the right anterior cingulate may lead self-generated thoughts to be experienced as external, producing spontaneous auditory hallucinations...
  2. ncbi request reprint Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD)
    H Szechtman
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Behav Neurosci 112:1475-85. 1998
    ..Quinpirole-induced compulsive checking may be an exaggeration of normal checking of home site in rats. Results suggest an animal model of obsessive-compulsive disorder and a role for dopamine in this disorder...
  3. pmc Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control
    H Szechtman
    Dept of Psychiatry and Behavioural Neurosciences, McMaster University, Canada
    BMC Neurosci 2:4. 2001
    ..For this purpose, the rat's home-cage was placed into the open field at the beginning or the middle of a 2-hr test...
  4. ncbi request reprint Increased TUNEL staining in brains of autoimmune Fas-deficient mice
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, HSC 4N77A, 1200 Main Street, Hamilton, Ontario, Canada
    J Neuroimmunol 104:147-54. 2000
    ....
  5. ncbi request reprint Immunosuppression prevents neuronal atrophy in lupus-prone mice: evidence for brain damage induced by autoimmune disease?
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada
    J Neuroimmunol 111:93-101. 2000
    ....
  6. ncbi request reprint Reduced corticotropin-releasing factor and enhanced vasopressin gene expression in brains of mice with autoimmunity-induced behavioral dysfunction
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Neuroimmunol 96:80-91. 1999
    ..Furthermore, they support the parallel between chronic stress and chronic autoimmunity/inflammation, and suggest common central mechanisms relevant to endocrine function and behavior...
  7. ncbi request reprint Progressive atrophy of pyramidal neuron dendrites in autoimmune MRL-lpr mice
    B Sakic
    Department of Psychiatry, McMaster University, Hamilton, Ontario, Canada
    J Neuroimmunol 87:162-70. 1998
    ..Reduced dendritic complexity may represent, at least in part, a structural basis for the altered behavioral profile of MRL-lpr mice...
  8. ncbi request reprint Behavioral effects of infection with IL-6 adenovector
    B Sakic
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Brain Behav Immun 15:25-42. 2001
    ..The inability of circulating IL-6 to alter other aspects of behavior supports the hypothesis that multiple immuno-neuroendocrine mechanisms contribute to the pathogenesis of AABS...
  9. ncbi request reprint Association of altered whole-body metabolism with locomotor sensitization induced by quinpirole
    D V Coscina
    Department of Psychology, University of Toronto, Ontario, Canada
    Physiol Behav 63:755-61. 1998
    ..This suggests that enhanced utilization of body lipids could be a separate physiological consequence of quinpirole that might support in part the heightened locomotor activity characteristic of the behavioral sensitization it induces...
  10. ncbi request reprint Monoamine oxidase inhibitor-induced blockade of locomotor sensitization to quinpirole: role of striatal dopamine uptake inhibition
    K E Culver
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, L8N 3Z5, Ontario, Canada
    Neuropharmacology 43:385-93. 2002
    ....
  11. ncbi request reprint Immunosuppressive treatment prevents behavioral deficit in autoimmune MRL-lpr mice
    B Sakic
    Department of Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada
    Physiol Behav 58:797-802. 1995
    ..The effect of cyclophosphamide in the MRL-lpr group is believed to reflect the suppression of pathogenic immune factor(s) that alter behavior during the onset of autoimmune disease...
  12. ncbi request reprint Differences in the behavioral profile of circling under amphetamine and apomorphine in rats with unilateral lesions of the substantia nigra
    M Ziegler
    McMaster University, Hamilton, Ontario, Canada
    Behav Neurosci 102:276-88, 327. 1988
    ..It seems, therefore, that different behavioral mechanisms may underlie the rotations induced by apomorphine and amphetamine...
  13. ncbi request reprint Spatial learning during the course of autoimmune disease in MRL mice
    B Sakic
    Department of Biomedical Sciences, McMaster University, Hamilton, Ont, Canada
    Behav Brain Res 54:57-66. 1993
    ....
  14. ncbi request reprint Obsessive-compulsive disorder as a disturbance of security motivation: constraints on comorbidity
    H Szechtman
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
    Neurotox Res 10:103-12. 2006
    ....
  15. ncbi request reprint Neurotoxic properties of cerebrospinal fluid from behaviorally impaired autoimmune mice
    D Maric
    Laboratory of Neurophysiology, NINDS, National Institute of Health, Bethesda, MD, USA
    Brain Res 920:183-93. 2001
    ..The present results suggest that CSF from the behaviorally impaired lupus-prone mice is neurotoxic and are consistent with the hypothesis that neuroactive metabolites are produced intrathecally in neuropsychiatric lupus erythematosus...
  16. ncbi request reprint Context gives meaning. Commentary on Badiani and Robinson drug-induced neurobehavioral plasticity: the role of environmental context
    H Szechtman
    Behav Pharmacol 15:381-5. 2004