Claudio N Soares

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. doi request reprint Menopausal transition, mood, and cognition: an integrated view to close the gaps
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Menopause 17:812-4. 2010
  2. ncbi request reprint Sleep disorders in women: clinical evidence and treatment strategies
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
    Psychiatr Clin North Am 29:1095-113; abstract xi. 2006
  3. ncbi request reprint Eszopiclone in patients with insomnia during perimenopause and early postmenopause: a randomized controlled trial
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada, and Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
    Obstet Gynecol 108:1402-10. 2006
  4. ncbi request reprint Effects and management of the menopausal transition in women with depression and bipolar disorder
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Clin Psychiatry 68:16-21. 2007
  5. ncbi request reprint Menopausal transition and depression: who is at risk and how to treat it?
    Claudio N Soares
    Women s Health Concerns Clinic, St Joseph s Healthcare Hamilton, 301 James St South, FB number 638, Hamilton, ON L8P 3B6, Canada
    Expert Rev Neurother 7:1285-93. 2007
  6. doi request reprint Paroxetine versus placebo for women in midlife after hormone therapy discontinuation
    Claudio N Soares
    Perinatal and Reproductive Psychiatry Program, Massachusetts General Hospital, Boston, USA
    Am J Med 121:159-162.e1. 2008
  7. pmc Reproductive hormone sensitivity and risk for depression across the female life cycle: a continuum of vulnerability?
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, Women s Health Concerns Clinic, McMaster University, Hamilton, Ontario, Canada
    J Psychiatry Neurosci 33:331-43. 2008
  8. pmc Can depression be a menopause-associated risk?
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    BMC Med 8:79. 2010
  9. ncbi request reprint Hormones in the treatment of depression
    Claudio N Soares
    Women s Health Concerns Clinic, Department of Psychiatry and Behaviour Neurosciences, McMaster University, Canada
    Womens Health (Lond Engl) 2:435-45. 2006
  10. doi request reprint Assessing the efficacy of desvenlafaxine for improving functioning and well-being outcome measures in patients with major depressive disorder: a pooled analysis of 9 double-blind, placebo-controlled, 8-week clinical trials
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, Mood Disorders Division, McMaster University, Hamilton, Ontario, L8P 3B6, Canada
    J Clin Psychiatry 70:1365-71. 2009

Detail Information

Publications56

  1. doi request reprint Menopausal transition, mood, and cognition: an integrated view to close the gaps
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Menopause 17:812-4. 2010
    ....
  2. ncbi request reprint Sleep disorders in women: clinical evidence and treatment strategies
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
    Psychiatr Clin North Am 29:1095-113; abstract xi. 2006
    ..This review focuses on clinical evidence for sleep disorders in women and discusses existing evidence of risk factors and treatment options for insomnia and sleep-disordered breathing in women...
  3. ncbi request reprint Eszopiclone in patients with insomnia during perimenopause and early postmenopause: a randomized controlled trial
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada, and Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
    Obstet Gynecol 108:1402-10. 2006
    ..To evaluate eszopiclone 3 mg for treatment of insomnia in perimenopausal and early postmenopausal women, as well as the impact of insomnia treatment on mood, menopause-related symptoms, and quality of life...
  4. ncbi request reprint Effects and management of the menopausal transition in women with depression and bipolar disorder
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Clin Psychiatry 68:16-21. 2007
    ..Insufficient information is available, however, to assess the best strategy to treat women with bipolar disorder and depression as they age...
  5. ncbi request reprint Menopausal transition and depression: who is at risk and how to treat it?
    Claudio N Soares
    Women s Health Concerns Clinic, St Joseph s Healthcare Hamilton, 301 James St South, FB number 638, Hamilton, ON L8P 3B6, Canada
    Expert Rev Neurother 7:1285-93. 2007
    ..Hormonal and nonhormonal factors that may contribute to the occurrence of physical and/or psychiatric complaints during the menopausal transition are discussed. Lastly, existing evidence-based treatment strategies are summarized...
  6. doi request reprint Paroxetine versus placebo for women in midlife after hormone therapy discontinuation
    Claudio N Soares
    Perinatal and Reproductive Psychiatry Program, Massachusetts General Hospital, Boston, USA
    Am J Med 121:159-162.e1. 2008
    ..This study examines the efficacy of paroxetine controlled-release versus placebo for the treatment of women with vasomotor symptoms after discontinuing hormone therapy...
  7. pmc Reproductive hormone sensitivity and risk for depression across the female life cycle: a continuum of vulnerability?
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, Women s Health Concerns Clinic, McMaster University, Hamilton, Ontario, Canada
    J Psychiatry Neurosci 33:331-43. 2008
    ..Last, we explore some of the clinical and therapeutic implications of hormone-modulated depression in women...
  8. pmc Can depression be a menopause-associated risk?
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    BMC Med 8:79. 2010
    ....
  9. ncbi request reprint Hormones in the treatment of depression
    Claudio N Soares
    Women s Health Concerns Clinic, Department of Psychiatry and Behaviour Neurosciences, McMaster University, Canada
    Womens Health (Lond Engl) 2:435-45. 2006
    ..This article reviews the current literature on the impact of hormonal treatments for mood symptoms in women and preventative strategies for depression in women during the reproductive lifecycle...
  10. doi request reprint Assessing the efficacy of desvenlafaxine for improving functioning and well-being outcome measures in patients with major depressive disorder: a pooled analysis of 9 double-blind, placebo-controlled, 8-week clinical trials
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, Mood Disorders Division, McMaster University, Hamilton, Ontario, L8P 3B6, Canada
    J Clin Psychiatry 70:1365-71. 2009
    ..To evaluate the effects of desvenlafaxine therapy on functioning and well-being in major depressive disorder (MDD)...
  11. doi request reprint Challenges and opportunities to manage depression during the menopausal transition and beyond
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, ON, Canada
    Psychiatr Clin North Am 33:295-308. 2010
    ..Hormonal and nonhormonal treatment strategies for depression and anxiety in this particular population are critically examined, although more tailored treatment options are still needed...
  12. doi request reprint A pilot, 8-week, placebo lead-in trial of quetiapine extended release for depression in midlife women: impact on mood and menopause-related symptoms
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Clin Psychopharmacol 30:612-5. 2010
    ..Main adverse effects included drowsiness and dry mouth. Based on these preliminary results, quetiapine XR should be further examined in larger, controlled trials for the management of depressed, symptomatic midlife women...
  13. doi request reprint Desvenlafaxine and escitalopram for the treatment of postmenopausal women with major depressive disorder
    Claudio N Soares
    McMaster University, Hamilton, Ontario, Canada
    Menopause 17:700-11. 2010
    ....
  14. ncbi request reprint Escitalopram versus ethinyl estradiol and norethindrone acetate for symptomatic peri- and postmenopausal women: impact on depression, vasomotor symptoms, sleep, and quality of life
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    Menopause 13:780-6. 2006
    ..To examine the efficacy and tolerability of escitalopram (ESCIT) compared to estrogen and progestogen therapy (EPT) for the treatment of symptomatic peri- and postmenopausal women...
  15. doi request reprint Open-label treatment with desvenlafaxine in postmenopausal women with major depressive disorder not responding to acute treatment with desvenlafaxine or escitalopram
    Claudio N Soares
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
    CNS Drugs 25:227-38. 2011
    ..Preliminary clinical evidence indicates that menopausal status might impact on the efficacy of certain classes of antidepressants...
  16. ncbi request reprint Insomnia in women: an overlooked epidemic?
    C N Soares
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Canada
    Arch Womens Ment Health 8:205-13. 2005
    ..Healthcare providers should be aware of the variety of pharmacologic and non-pharmacologic options for treatment of insomnia and, in particular, be able to weigh their efficacy against the risks of side effects and next-day sedation...
  17. ncbi request reprint Treatment of premenstrual worsening of depression with adjunctive oral contraceptive pills: a preliminary report
    Hadine Joffe
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:1954-62. 2007
    ..Oral contraceptive pills (OCPs) stabilize reproductive hormones and treat premenstrual dysphoric disorder. Management of depression that breaks through premenstrually has not been studied...
  18. ncbi request reprint Efficacy of citalopram as a monotherapy or as an adjunctive treatment to estrogen therapy for perimenopausal and postmenopausal women with depression and vasomotor symptoms
    Claudio N Soares
    Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital and the Department of Psychiatry, Harvard Medical School, Boston, 02114, USA
    J Clin Psychiatry 64:473-9. 2003
    ..It is still unclear whether the use of antidepressants alone may alleviate menopause-related mood and vasomotor symptoms or enhance the response observed with short-term use of estrogen therapy...
  19. ncbi request reprint Risk for new onset of depression during the menopausal transition: the Harvard study of moods and cycles
    Lee S Cohen
    Perinatal and Reproductive Psychiatry Clinical Research Program and Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, 02114, USA
    Arch Gen Psychiatry 63:385-90. 2006
    ..However, it is unclear whether this period is one of increased risk for major depressive disorder, particularly for women who have not had a previous episode of depression...
  20. ncbi request reprint Short-term use of estradiol for depression in perimenopausal and postmenopausal women: a preliminary report
    Lee S Cohen
    Perinatal and Reproductive Psychiatry Clinical Research Program and Vicent Memorail Obstetrics and Gynecology Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 160:1519-22. 2003
    ..The authors examined the effect of a 4-week course of estrogen therapy on depression in perimenopausal and postmenopausal women...
  21. ncbi request reprint Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Mass 02114, USA
    J Clin Psychiatry 68:943-50. 2007
    ..Treatment strategies that target all of these symptoms together have not been investigated to date...
  22. ncbi request reprint Paroxetine controlled release for premenstrual dysphoric disorder: a double-blind, placebo-controlled trial
    Lee S Cohen
    Perinatal and Reproductive Psychiatry Program, Massachusetts General Hospital, 15 Parkman Street, WACC 812, Boston, MA 02114, USA
    Psychosom Med 66:707-13. 2004
    ..This study was designed to assess the efficacy and tolerability of multiple doses of paroxetine controlled release (CR) in PMDD...
  23. doi request reprint Effects of quetiapine extended release on sleep and quality of life in midlife women with major depressive disorder
    Benicio N Frey
    Women s Health Concerns Clinic, Hamilton, Ontario, Canada
    Arch Womens Ment Health 16:83-5. 2013
    ..While larger, controlled trials are still awaited, these preliminary results are encouraging and suggest that quetiapine XR may be a useful tool in treating symptomatic midlife women with MDD...
  24. ncbi request reprint Assessment and treatment of hot flushes and menopausal mood disturbance
    Hadine Joffe
    Department of Psychiatry, Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, WACC, Boston, MA 02114, USA
    Psychiatr Clin North Am 26:563-80. 2003
    ..As further evidence of the benefits of psychoactive medications for menopausal symptoms is established, the choice between using hormonal and nonhormonal therapies for management of menopausal symptoms will continue to evolve...
  25. pmc Depression is associated with worse objectively and subjectively measured sleep, but not more frequent awakenings, in women with vasomotor symptoms
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Menopause 16:671-9. 2009
    ..We aimed to determine if objectively measured sleep and perceived sleep quality are worse in depressed women with VMS than in nondepressed women with VMS...
  26. ncbi request reprint Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: the Harvard Study of Moods and Cycles
    Bernard L Harlow
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115, USA
    Arch Gen Psychiatry 60:29-36. 2003
    ..Few studies have determined the impact of a lifetime history of major depression on an early transition to menopause...
  27. ncbi request reprint Relative antidepressant efficacy of bupropion and the selective serotonin reuptake inhibitors in major depressive disorder: gender-age interactions
    George I Papakostas
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Int Clin Psychopharmacol 22:226-9. 2007
    ..This finding could, however, not be replicated when improvement in anxious/somatic symptoms was defined as a continuous measure...
  28. ncbi request reprint Depression during menopausal transition: a review of treatment strategies and pathophysiological correlates
    Benicio N Frey
    Women s Health Concerns Clinic WHCC, Department of Psychiatry and Behavioural Neurosciences, McMaster University, James Street South, FB 638, Hamilton, ON L8P 3B6, Canada
    Menopause Int 14:123-8. 2008
    ..The identification of individuals whom might be at a higher risk for depression during menopausal transition could guide preventive strategies for this population...
  29. pmc Psychosocial predictors of the onset of anxiety disorders in women: results from a prospective 3-year longitudinal study
    Amanda W Calkins
    Boston University, Boston, MA 02215, USA
    J Anxiety Disord 23:1165-9. 2009
    ..These findings from a prospective longitudinal study are discussed in relation to the potential role of such predictors in primary or relapse prevention efforts...
  30. ncbi request reprint Efficacy and tolerability of premenstrual use of venlafaxine (flexible dose) in the treatment of premenstrual dysphoric disorder
    Lee S Cohen
    Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital MGH, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychopharmacol 24:540-3. 2004
    ..05 for all comparisons, Wilcoxon tests). Intermittent treatment was well tolerated. This preliminary report suggests that premenstrual use of venlafaxine is an efficacious and well-tolerated treatment for premenstrual dysphoric disorder...
  31. ncbi request reprint Vasomotor symptoms are associated with depression in perimenopausal women seeking primary care
    Hadine Joffe
    Perinatal and Reproductive Psychiatry Program, Reproductive Endocrine Unit, and Medical Service, Massachusetts General Hospital, Boston, MA, USA
    Menopause 9:392-8. 2002
    ..To compare the relationship between vasomotor symptoms (hot flushes and night sweats) and depression in perimenopausal women with that in postmenopausal and older premenopausal women...
  32. ncbi request reprint Diagnosis and management of mood disorders during the menopausal transition
    Lee S Cohen
    Department of Perinatal and Reproductive Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med 118:93-7. 2005
    ..The benefits and risks of using hormonal and nonhormonal strategies for the management of depression and other menopause-related somatic symptoms are critically reviewed...
  33. ncbi request reprint Antidepressant response and well-being in pre-, peri- and postmenopausal women with major depressive disorder treated with fluoxetine
    Paolo Cassano
    The Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychother Psychosom 74:362-5. 2005
    ..We assessed the impact of menopausal status on treatment response and well-being in a cohort of outpatient women with major depressive disorder (DSM-III-R criteria), who received treatment with fluoxetine (20 mg/day for 8 weeks)...
  34. doi request reprint Non-hormonal treatment strategies for vasomotor symptoms: a critical review
    Elise Hall
    Mood Disorders Division and Women s Health Concerns Clinic, McMaster University, Hamilton, Ontario, Canada
    Drugs 71:287-304. 2011
    ..Clinicians should therefore be able to tailor treatment strategies for those who are unable or unwilling to use hormones to alleviate VMS and improve overall functioning and quality of life...
  35. ncbi request reprint Depression in peri- and postmenopausal women: prevalence, pathophysiology and pharmacological management
    Claudio N Soares
    Women s Health Concerns Clinic, St Joseph s Healthcare Hamilton, Hamilton, ON, Canada
    Drugs Aging 30:677-85. 2013
    ..Other evidence-based treatment options (hormonal, pharmacological, behavioural) are available to clinicians and health professionals who care for this population...
  36. pmc Stress response in postpartum women with and without obsessive-compulsive symptoms: an fMRI study
    Catherine Lord
    Women s Health Concerns Clinic, St Joseph s Healthcare and Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ont
    J Psychiatry Neurosci 37:78-86. 2012
    ..This study aimed to examine the cerebral, psychologic and endocrine correlates of the stress response in patients with OCD and during the postpartum period...
  37. doi request reprint Piloting the perinatal obsessive-compulsive scale (POCS): development and validation
    Catherine Lord
    Women s Health Concerns Clinic, St Joseph s Healthcare, 301 James Street South, Hamilton, ON L8P 3B6, Canada
    J Anxiety Disord 25:1079-84. 2011
    ..The POCS helps clinicians detect perinatal OCD while giving perinatal women an opportunity to openly discuss socially sensitive issues...
  38. doi request reprint The Premenstrual Symptoms Screening Tool revised for adolescents (PSST-A): prevalence of severe PMS and premenstrual dysphoric disorder in adolescents
    Meir Steiner
    Women s Health Concerns Clinic, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Arch Womens Ment Health 14:77-81. 2011
    ..Severe PMS and PMDD present with similar rates and symptoms in adolescents as in adults, and the Premenstrual Symptoms Screening Tool modified for adolescents is a fast, reliable tool to screen for these syndromes in adolescents...
  39. ncbi request reprint Bupropion SR for the treatment of postpartum depression: a pilot study
    Ruta M Nonacs
    Perinatal and Reproductive Psychiatry Clinical Research Program, Massachusetts General Hospital MGH, Boston, 02114, USA
    Int J Neuropsychopharmacol 8:445-9. 2005
    ..5 (range 37.5-300). Bupropion SR was well tolerated, and no subjects discontinued treatment as a result of medication side-effects. Bupropion SR represents an effective and well-tolerated antidepressant for the treatment of PPD...
  40. ncbi request reprint Prevalence and predictors of premenstrual dysphoric disorder (PMDD) in older premenopausal women. The Harvard Study of Moods and Cycles
    Lee S Cohen
    Harvard Medical School, Boston, MA, USA
    J Affect Disord 70:125-32. 2002
    ..Consistent data on the prevalence and predictors of premenstrual dysphoric disorder (PMDD) in the general population are lacking...
  41. ncbi request reprint [Trauma & the reproductive lifecycle in women]
    Leslie Born
    Clínica de Preocupações com a Saúde da Mulher, St Joseph s Healthcare, Hamilton, Canada
    Rev Bras Psiquiatr 27:S65-72. 2005
    ..Current options available for the treatment of such symptoms, including group and counselling therapies and debriefing are critically reviewed...
  42. ncbi request reprint Menopause and mood
    Claudio N Soares
    Center for Women s Mental Health, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Obstet Gynecol 47:576-91. 2004
  43. ncbi request reprint Effect of reproductive hormones and selective estrogen receptor modulators on mood during menopause
    Claudio N Soares
    Harvard Medical School, MGH Center for Women s Mental Health, Boston, Massachusetts 02114, USA
    Drugs Aging 20:85-100. 2003
    ..There are some preliminary data suggesting the efficacy of antidepressants for the treatment of hot flushes; existing data on diet supplements and herbal products have shown more mixed results...
  44. ncbi request reprint Antenatal depression in a multi-ethnic, community sample of Canadian immigrants: psychosocial correlates and hypothalamic-pituitary-adrenal axis function
    Miki Peer
    Student, Institute of Medical Science, University of Toronto, Toronto, Ontario Student, Women s Health Concerns Clinic, St Joseph s Healthcare Hamilton, Hamilton, Ontario
    Can J Psychiatry 58:579-87. 2013
    ..We aimed to examine the factors associated with prenatal depressive symptoms, including altered HPA axis function, in an ethnically diverse community sample of Canadian immigrant women...
  45. doi request reprint Cognitive-behavioral group treatment for menopausal symptoms: a pilot study
    Sheryl M Green
    Department of Psychiatry and Behavioural Neurosciences, McMaster University and Women s Health Concerns Clinic, St Joseph s Healthcare, Hamilton, Ontario, Canada
    Arch Womens Ment Health 16:325-32. 2013
    ..Further studies are needed on its efficacy through larger, controlled trials...
  46. ncbi request reprint Practical strategies for diagnosing and treating depression in women: menopausal transition
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Clin Psychiatry 69:e30. 2008
    ..Possible treatment options to be considered include the adequate use of hormone replacement therapy, antidepressants, psychotherapy, and other psychotropic agents...
  47. ncbi request reprint Women and reproductive-related trauma
    Leslie Born
    Women s Health Concerns Clinic, Room FB 639 St Joseph s Healthcare, 50 Charlton Ave E, Hamilton, Ontario, Canada L8N 4A6
    Ann N Y Acad Sci 1071:491-4. 2006
    ..g., miscarriage, stillbirth) or who experienced reemergence of symptoms during pregnancy is presented, including treatment strategies...
  48. doi request reprint Physiological stress response in postpartum women with obsessive-compulsive disorder: A pilot study
    Catherine Lord
    Women Health Concerns Clinic, St Joseph s Healthcare, Fontbonne Building, 301 James Street South, Hamilton, Canada
    Psychoneuroendocrinology 36:133-8. 2011
    ....
  49. ncbi request reprint Treatment of menopause-related mood disturbances
    Claudio N Soares
    Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, ON, Canada
    CNS Spectr 10:489-97. 2005
    ....
  50. ncbi request reprint The rapid effects of estrogen: a mini-review
    Sonali Lokuge
    Women s Health Concerns Clinic, Hamilton, Ontario, Canada
    Behav Pharmacol 21:465-72. 2010
    ....
  51. ncbi request reprint Depression in women: windows of vulnerability and new insights into the link between estrogen and serotonin
    Sonali Lokuge
    Women s Health Concerns Clinic, St Joseph s Healthcare Hamilton, Ontario, Canada
    J Clin Psychiatry 72:e1563-9. 2011
    ..These effects may have direct implications on female mood disorders such as premenstrual disorders and depression during pregnancy, postpartum, and during the menopausal transition...
  52. doi request reprint Shift in the brain network of emotional regulation in midlife women: is the menopausal transition the turning point?
    Benicio N Frey
    Women s Health Concerns Clinic, St Joseph Healthcare, Hamilton, Ontario, Canada
    Menopause 17:840-5. 2010
    ..The aim of this study was to examine the brain correlates of emotional regulation in healthy, nondepressed midlife women...
  53. doi request reprint Changes in cortical thickness across the lifespan in major depressive disorder
    Wanda Truong
    McMaster Integrative Neuroscience Discovery and Study Program MiNDS, McMaster University, Hamilton, ON, Canada L8S 4K1
    Psychiatry Res 214:204-11. 2013
    ..EOD is associated with greater disturbances in cortical thickness than LOD, even when duration of illness and other factors are controlled. These results provide novel insights on how development of depression is differentiated by age. ..
  54. pmc Steroid concentrations in antepartum and postpartum saliva: normative values in women and correlations with serum
    Elizabeth Hampson
    Department of Psychology and Graduate Program in Neuroscience, University of Western Ontario, London, ON, Canada
    Biol Sex Differ 4:7. 2013
    ..Little normative information is available concerning expected concentrations of the major reproductive steroids in saliva during pregnancy and the extended postpartum...
  55. doi request reprint Early improvement in depressive symptoms with desvenlafaxine 50 mg/d as a predictor of treatment success in patients with major depressive disorder
    Claudio N Soares
    From McMaster University and St Joseph s Healthcare, Hamilton, Ontario, Canada Pfizer Inc, New York, NY and Formerly of Pfizer Inc, Collegeville, PA
    J Clin Psychopharmacol 34:57-65. 2014
    ..This post hoc analysis assessed the predictive value of improvement in depressive scores at early time points for treatment outcomes at week 8 in patients with major depressive disorder treated with desvenlafaxine 50 mg/d or placebo...
  56. doi request reprint Assessing the relationship between functional impairment/recovery and depression severity: a pooled analysis
    Christine J Guico-Pabia
    Pfizer Inc, Collegeville, Pennsylvania 19426, USA
    Int Clin Psychopharmacol 27:1-7. 2012
    ..A better understanding of the relationship between depressive symptoms and functional impairment and well-being may provide clinicians with a more comprehensive means of assessing treatment effects in major depressive disorder...