Barbara Schmidt

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi request reprint Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants
    B Schmidt
    Department of Pediatrics, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 344:1966-72. 2001
  2. ncbi request reprint Long-term effects of caffeine therapy for apnea of prematurity
    Barbara Schmidt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    N Engl J Med 357:1893-902. 2007
  3. ncbi request reprint Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP)
    Barbara Schmidt
    Department of Pediatrics and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Pediatr 148:730-734. 2006
  4. ncbi request reprint Caffeine therapy for apnea of prematurity
    Barbara Schmidt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 354:2112-21. 2006
  5. doi request reprint Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity
    Barbara Schmidt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    JAMA 307:275-82. 2012
  6. ncbi request reprint Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial
    Barbara Schmidt
    Department of Pediatrics, McMaster University, Hamilton, Canada
    Biol Neonate 88:208-13. 2005
  7. ncbi request reprint Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms
    Barbara Schmidt
    Department of Pediatrics, McMaster University, HSC 3N11E, 1200 Main St W, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 289:1124-9. 2003
  8. ncbi request reprint Male/female differences in indomethacin effects in preterm infants
    Arne Ohlsson
    University of Toronto, Toronto, McMaster University, Hamilton, Ontario, Canada
    J Pediatr 147:860-2. 2005
  9. ncbi request reprint Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: results from the Trial of Indomethacin Prophylaxis in Preterms
    Nandkishor S Kabra
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    J Pediatr 150:229-34, 234.e1. 2007
  10. doi request reprint Prevention and 18-month outcomes of serious pulmonary hemorrhage in extremely low birth weight infants: results from the trial of indomethacin prophylaxis in preterms
    Khalid Alfaleh
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatrics 121:e233-8. 2008

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants
    B Schmidt
    Department of Pediatrics, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 344:1966-72. 2001
    ..Whether prophylaxis with indomethacin confers any long-term benefits that outweigh the risks of drug-induced reductions in renal, intestinal, and cerebral blood flow is not known...
  2. ncbi request reprint Long-term effects of caffeine therapy for apnea of prematurity
    Barbara Schmidt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    N Engl J Med 357:1893-902. 2007
    ..Methylxanthine therapy is commonly used for apnea of prematurity but in the absence of adequate data on its efficacy and safety. It is uncertain whether methylxanthines have long-term effects on neurodevelopment and growth...
  3. ncbi request reprint Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP)
    Barbara Schmidt
    Department of Pediatrics and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Pediatr 148:730-734. 2006
    ....
  4. ncbi request reprint Caffeine therapy for apnea of prematurity
    Barbara Schmidt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 354:2112-21. 2006
    ..It is uncertain whether methylxanthines have other short- and long-term benefits or risks in infants with very low birth weight...
  5. doi request reprint Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity
    Barbara Schmidt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    JAMA 307:275-82. 2012
    ..Very preterm infants are prone to apnea and have an increased risk of death or disability. Caffeine therapy for apnea of prematurity reduces the rates of cerebral palsy and cognitive delay at 18 months of age...
  6. ncbi request reprint Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial
    Barbara Schmidt
    Department of Pediatrics, McMaster University, Hamilton, Canada
    Biol Neonate 88:208-13. 2005
    ..Once this project is completed, caffeine will be one of the most rigorously evaluated neonatal therapies...
  7. ncbi request reprint Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms
    Barbara Schmidt
    Department of Pediatrics, McMaster University, HSC 3N11E, 1200 Main St W, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 289:1124-9. 2003
    ..Despite more than 2 decades of outcomes research after very preterm birth, clinicians remain uncertain about the extent to which neonatal morbidities predict poor long-term outcomes of extremely low-birth-weight (ELBW) infants...
  8. ncbi request reprint Male/female differences in indomethacin effects in preterm infants
    Arne Ohlsson
    University of Toronto, Toronto, McMaster University, Hamilton, Ontario, Canada
    J Pediatr 147:860-2. 2005
    ..A secondary analysis was performed in the entire "Trial of Indomethacin Prophylaxis in Preterms study" cohort. The results suggest a weak differential treatment effect of indomethacin by sex...
  9. ncbi request reprint Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: results from the Trial of Indomethacin Prophylaxis in Preterms
    Nandkishor S Kabra
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    J Pediatr 150:229-34, 234.e1. 2007
    ....
  10. doi request reprint Prevention and 18-month outcomes of serious pulmonary hemorrhage in extremely low birth weight infants: results from the trial of indomethacin prophylaxis in preterms
    Khalid Alfaleh
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatrics 121:e233-8. 2008
    ..We also compared the 18-month outcomes of infants with and without a serious pulmonary bleed...
  11. pmc Using a count of neonatal morbidities to predict poor outcome in extremely low birth weight infants: added role of neonatal infection
    Dirk Bassler
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatrics 123:313-8. 2009
    ..Neonatal infection has also been linked with later impairment. We examined whether the addition of infection to the count of 3 neonatal morbidities further improves the prediction of poor outcome...
  12. ncbi request reprint Controversies surrounding xanthine therapy
    David Millar
    Department of Paediatrics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5
    Semin Neonatol 9:239-44. 2004
    ..An international controlled clinical trial is underway to examine the long-term efficacy and safety of methylxanthine therapy in very low birth weight babies...
  13. ncbi request reprint Heat Loss Prevention (HeLP) in the delivery room: A randomized controlled trial of polyethylene occlusive skin wrapping in very preterm infants
    Sunita Vohra
    Department of Pediatrics, McMaster University, the Children s Hospital of Hamilton Health Sciences, Hamilton, Ontario, Canada
    J Pediatr 145:750-3. 2004
    ..To determine if polyethylene occlusive skin wrapping of very preterm infants prevents heat loss after delivery better than conventional drying and to evaluate if any benefit is sustained after wrap removal...
  14. ncbi request reprint Evidence-based neonatology: making a difference beyond discharge from the neonatal nursery
    JoAnn Harrold
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Pediatr 14:165-9. 2002
    ..Thyroxine supplementation for premature infants and head cooling for asphyxiated term infants require further study and should not be prescribed outside of rigorous clinical trials...
  15. ncbi request reprint Positive end-expiratory pressure above lower inflection point minimizes influx of activated neutrophils into lung
    Shelley L Monkman
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Crit Care Med 32:2471-5. 2004
    ..To compare the effects of low vs. high tidal volume (Vt) with three positive end-expiratory pressure (PEEP) strategies on activated neutrophil influx into the lung...
  16. ncbi request reprint Antithrombin replacement in neonates: is there any indication?
    Dirk Bassler
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Thromb Res 118:107-11. 2006
    ..It has been hypothesised that treatment of the acquired AT deficiency with AT concentrate may improve the outcome of conditions such as the neonatal respiratory distress syndrome (RDS), intracranial hemorrhage (ICH) and sepsis...
  17. doi request reprint Evidence-based neonatal drug therapy for prevention of bronchopulmonary dysplasia in very-low-birth-weight infants
    Barbara Schmidt
    Department of Pediatrics, Children s Hospital of Philadelphia and The University of Pennsylvania, Philadelphia, PA 19104, USA
    Neonatology 93:284-7. 2008
    ..However, when given during the 2nd week of life to infants at high risk of BPD corticosteroids may have important short- and long-term benefits. These should be urgently confirmed or refuted in well-designed controlled trials...
  18. ncbi request reprint Evaluating "old" definitions for the "new" bronchopulmonary dysplasia
    Peter G Davis
    Department of Paediatrics, Royal Women s Hospital, Melbourne, Victoria, Australia
    J Pediatr 140:555-60. 2002
    ..To examine the accuracy of different criteria for the diagnosis of bronchopulmonary dysplasia (BPD), based on the final age at which oxygen therapy was stopped, in predicting pulmonary and neurologic outcomes at 18-month corrected age...
  19. ncbi request reprint Retrospective economic evaluation of a controlled trial of indomethacin prophylaxis for patent ductus arteriosus in premature infants
    John A F Zupancic
    Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Early Hum Dev 82:97-103. 2006
    ..To determine the incremental cost-effectiveness of indomethacin prophylaxis in extremely low birth weight infants enrolled in the Trial of Indomethacin Prophylaxis in Preterms (TIPP)...
  20. ncbi request reprint Ibuprofen prophylaxis in preterm neonates
    Barbara Schmidt
    Lancet 360:492. 2002
  21. ncbi request reprint Daily cost prediction model in neonatal intensive care
    John A F Zupancic
    Department of Neonatology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02458, USA
    Int J Technol Assess Health Care 19:330-8. 2003
    ..To reduce this data collection burden, we identified the key resource items that predict daily ancillary costs for extremely low birth weight infants...
  22. ncbi request reprint A novel model of selective lung ventilation to investigate the long-term effects of ventilation-induced lung injury
    Torsten Schreiber
    Department of Anesthesiology and Intensive Care Medicine, Friedrich Schiller Universitaet Jena, Jena, Germany
    Shock 26:50-4. 2006
    ..This animal model permits assessment of the long-term course of ventilation-induced lung injury and shows that pulmonary inflammation and histological alterations are present 24 h after unilateral injurious ventilation...
  23. ncbi request reprint Effects of a catecholamine-induced increase in cardiac output on lung injury after experimental unilateral pulmonary acid instillation
    Torsten Schreiber
    Department of Anesthesiology and Intensive Care Medicine, Friedrich Schiller Universitat Jena, Jena, Germany
    Crit Care Med 35:1741-8. 2007
    ..We sought to determine the effects of increased cardiac output on markers of lung injury in an in vivo model of inhomogeneous lung perfusion and injury...
  24. ncbi request reprint Preemie abandonment? Multidisciplinary experts consider how to best meet preemies needs at "preterm infants: a collaborative approach to specialized care" roundtable
    Heidelise Als
    Harvard Medical School Children s Hospital, Boston, USA
    Mod Healthc 37:17-24. 2007
    ....
  25. ncbi request reprint PEEP has beneficial effects on inflammation in the injured and no deleterious effects on the noninjured lung after unilateral lung acid instillation
    Torsten Schreiber
    Department of Anesthesiology and Intensive Care Medicine, Friedrich Schiller University, Erlanger Allee 101, 07747, Jena, Germany
    Intensive Care Med 32:740-9. 2006
    ..We compared the effects of PEEP on the inflammatory response in injured and noninjured regions of the lung in an animal model of unilateral lung acid instillation...
  26. ncbi request reprint Increased susceptibility to ventilator-associated lung injury persists after clinical recovery from experimental endotoxemia
    Torsten Schreiber
    Department of Anesthesiology and Intensive Care Medicine, Friedrich Schiller Universitaet, Jena, Germany
    Anesthesiology 104:133-41. 2006
    ..However, it is unclear whether increased susceptibility to ventilator-associated lung injury is still present after clinical recovery from a transient endotoxin challenge...
  27. pmc Sustaining better diabetes care in remote indigenous Australian communities
    Robyn McDermott
    Tropical Public Health Unit, Queensland Health, Cairns, QLD 4870, Australia
    BMJ 327:428-30. 2003
    ..This study looked at whether those improvements were sustained two years after the end of the trial...