Research Topics
Species | Stuart M PhillipsSummaryAffiliation: McMaster University Country: Canada Publications
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Publications
Dietary protein for athletes: from requirements to metabolic advantageStuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 31:647-54. 2006..A framework for understanding dietary protein intake within the context of weight loss and athletic performance is laid out...
Increased muscle oxidative potential following resistance training induced fibre hypertrophy in young menJason E Tang
Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 31:495-501. 2006..We conclude that resistance training provides a stimulus for improving muscle oxidative potential, as reflected by the increased activities of CS and beta-HAD following resistance training induced hypertrophy...
Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly menYifan Yang
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St, West, Hamilton, ON, Canada, L8S 4K1
Nutr Metab (Lond) 9:57. 2012..abstract:..
Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolismTyler A Churchward-Venne
Department of Kinesiology, McMaster University, Hamilton, ON, Canada
Nutr Metab (Lond) 9:40. 2012....
Nutrient-rich meat proteins in offsetting age-related muscle lossStuart M Phillips
McMaster University, Department of Kinesiology, Hamilton, ON, Canada
Meat Sci 92:174-8. 2012..The focus of this paper is on the types of dietary protein that people might reasonably consume to offset sarcopenic muscle loss...
Associations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight trainingDaniel W D West
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON, L8S 4K1, Canada
Eur J Appl Physiol 112:2693-702. 2012..We report that the acute exercise-induced systemic hormonal responses of cortisol and GH are weakly correlated with resistance training-induced changes in fibre CSA and LBM (cortisol only), but not with changes in strength...
Dietary protein for athletes: from requirements to optimum adaptationStuart M Phillips
Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada
J Sports Sci 29:S29-38. 2011..Elevated protein consumption, as high as 1.8-2.0 g · kg(-1) · day(-1) depending on the caloric deficit, may be advantageous in preventing lean mass losses during periods of energy restriction to promote fat loss...
Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageingLeigh Breen
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Nutr Metab (Lond) 8:68. 2011..Resistance exercise combined with amino acid ingestion elicits the greatest anabolic response and may assist elderly in producing a 'youthful' muscle protein synthetic response provided sufficient protein is ingested following exercise...
Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humansNicholas A Burd
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Nutr Metab (Lond) 8:15. 2011..abstract:..
Resistance exercise: good for more than just Grandma and Grandpa's musclesStuart M Phillips
Exercise Metabolism Research Group, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1
Appl Physiol Nutr Metab 32:1198-205. 2007....
Effects of capsinoid ingestion on energy expenditure and lipid oxidation at rest and during exerciseAndrea R Josse
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
Nutr Metab (Lond) 7:65. 2010..We aimed to determine how ingestion of capsinoids affected energy expenditure, lipid oxidation and blood metabolites at rest and during moderate intensity exercise...
Dietary protein to support anabolism with resistance exercise in young menStuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1 Canada
J Am Coll Nutr 24:134S-139S. 2005....
Uncomplicated resistance training and health-related outcomes: evidence for a public health mandateStuart M Phillips
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Curr Sports Med Rep 9:208-13. 2010..We propose a more feasible and easier-to-adhere-to paradigm for RT that could affect how RT is viewed and adopted as a prescription for public health...
Alterations of protein turnover underlying disuse atrophy in human skeletal muscleS M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Appl Physiol 107:645-54. 2009..Thus the normal diurnal fasted-to-fed cycle of protein balance is disrupted and, by default, proteolysis becomes dominant but is not enhanced...
The role of milk- and soy-based protein in support of muscle protein synthesis and muscle protein accretion in young and elderly personsStuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
J Am Coll Nutr 28:343-54. 2009..This review focuses on evidence showing the differences in responses of MPS, and ultimately muscle protein accretion, to consumption of milk- and soy-based supplemental protein sources in humans...
Body-weight-support treadmill training improves blood glucose regulation in persons with incomplete spinal cord injuryStuart M Phillips
Department of Kinesiology, Exercise and Metabolism Research Group, Centre for Health Promotion and Rehabilitation, McMaster University, 1280 Main St West, Hamilton, ON, Canada L8S 4K1
J Appl Physiol 97:716-24. 2004..Increases in the capacity for transport and phosphorylation glucose in skeletal muscle likely play a role in these adaptations...
Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects)Stuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 34:403-10. 2009..What is less well understood is how the intensity and volume of the resistance exercise stimulus is sufficient to result in rises in MPS. Recent advances in this area are discussed here, with a focus on human in vivo data...
Protein requirements and supplementation in strength sportsStuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Nutrition 20:689-95. 2004..Strength-trained athletes should consume protein consistent with general population guidelines, or 12% to 15% of energy from protein...
Resistance exercise and strong healthy children: safe when done right!Stuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St W, Hamilton, ON L8S4K1, Canada
Appl Physiol Nutr Metab 33:545-6. 2008..This is an understudied area that is still lacking in key areas of research to establish efficacy, dose-response relationships, and other health benefits...
The science of muscle hypertrophy: making dietary protein countStuart M Phillips
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, Canada
Proc Nutr Soc 70:100-3. 2011..Thus, the combined evidence suggests a strategic advantage of practising early post-exercise consumption of whey protein or dairy-based protein to promote muscle protein synthesis, net muscle protein accretion and ultimately hypertrophy...
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young menNicholas A Burd
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
J Physiol 588:3119-30. 2010..These data suggest that 3SET of resistance exercise is more anabolic than 1SET and may lead to greater increases in myofibrillar protein accretion over time...
Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young menElisa I Glover
Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, 1280 Main St West, Hamilton, ON, Canada L8S 4K1
Am J Physiol Regul Integr Comp Physiol 295:R604-10. 2008..We conclude that resistance exercise potentiates the effect of feeding on the phosphorylation and presumably activation of critical proteins involved in the regulation of muscle protein synthesis in young men...
Carbohydrate does not augment exercise-induced protein accretion versus protein aloneAaron W Staples
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 43:1154-61. 2011..We tested the thesis that CHO and protein coingestion would augment muscle protein synthesis (MPS) and inhibit muscle protein breakdown (MPB) at rest and after resistance exercise...
Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusionElisa I Glover
Department of Kinesiology Exercise Metabolism Research Group, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
J Physiol 586:6049-61. 2008..The immobilization-induced decline in post-absorptive MPS with the 'anabolic resistance' to amino acids can account for much of immobilization-induced muscle atrophy...
Coingestion of protein with carbohydrate during recovery from endurance exercise stimulates skeletal muscle protein synthesis in humansKrista R Howarth
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Appl Physiol 106:1394-402. 2009..However, adding protein or additional CHO to a feeding strategy that provided 1.2 g CHO x kg(-1) x h(-1) did not further enhance glycogen resynthesis during recovery...
Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightliftersJoseph W Hartman
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
Am J Clin Nutr 86:373-81. 2007..Acute consumption of fat-free fluid milk after resistance exercise promotes a greater positive protein balance than does soy protein...
Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in menTyler A Churchward-Venne
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Physiol 590:2751-65. 2012....
Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly menNicholas A Burd
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
Br J Nutr 108:958-62. 2012..This result is probably related to a greater hyperaminoacidaemia or leucinaemia with whey ingestion...
Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in menNicholas A Burd
McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1
J Physiol 590:351-62. 2012....
Addition of glutamine to essential amino acids and carbohydrate does not enhance anabolism in young human males following exerciseSarah B Wilkinson
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St. West, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 31:518-29. 2006..The addition of glutamine to a CHO + EAA beverage had no effect on post-exercise muscle glycogen resynthesis or muscle protein synthesis, but may suppress a rise in whole-body proteolysis during the later stages of recovery...
Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young menNicholas A Burd
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
PLoS ONE 5:e12033. 2010..We aimed to determine the effect of resistance exercise intensity (%1 repetition maximum-1RM) and volume on muscle protein synthesis, anabolic signaling, and myogenic gene expression...
Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exerciseJason E Tang
Department of Kinesiology, McMaster University, Hamilton, ON, Canada
J Nutr 141:195-200. 2011..Furthermore, arginine does not enhance mixed or myofibrillar MPS either at rest or after resistance exercise beyond that achieved by feeding alone...
Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young menNicholas A Burd
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
J Nutr 141:568-73. 2011..Our results suggest that resistance exercise performed until failure confers a sensitizing effect on human skeletal muscle for at least 24 h that is specific to the myofibrillar protein fraction...
Resistance training reduces fasted- and fed-state leucine turnover and increases dietary nitrogen retention in previously untrained young menDaniel R Moore
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Nutr 137:985-91. 2007..The increase in nitrogen balance after training demonstrates a more efficient utilization of dietary nitrogen, suggesting that protein requirements for novice weightlifters are not elevated...
Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young menJason E Tang
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 32:1132-8. 2007....
Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young menDaniel R Moore
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
Am J Clin Nutr 89:161-8. 2009..The anabolic effect of resistance exercise is enhanced by the provision of dietary protein...
Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young menDaniel W D West
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
J Physiol 587:5239-47. 2009..Local mechanisms are likely to be of predominant importance for the post-exercise increase in MPS...
Low-volume resistance exercise attenuates the decline in strength and muscle mass associated with immobilizationBryan R Oates
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
Muscle Nerve 42:539-46. 2010..01). A minimal volume (140 contractions in 14 days) of resistive exercise is an effective countermeasure against immobilization-induced atrophy of the quadriceps femoris but is only partially effective for the triceps surae...
Resistance exercise load does not determine training-mediated hypertrophic gains in young menCameron J Mitchell
Exercise Metabolism Research Group, Department of Kinesiology, McMaster Univ, 1280 Main St, West, Hamilton, Ontario, L8S4L8, Canada
J Appl Physiol 113:71-7. 2012..In accordance with our previous acute measurements of muscle protein synthetic rates a lower load lifted to failure resulted in similar hypertrophy as a heavy load lifted to failure...
Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young menJason E Tang
Department of Kinesiology Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario L8S 4K1, Canada
J Appl Physiol 107:987-92. 2009..These differences may be related to how quickly the proteins are digested (i.e., fast vs. slow) or possibly to small differences in leucine content of each protein...
Resistance training reduces whole-body protein turnover and improves net protein retention in untrained young malesJoseph W Hartman
Exercise Metabolism Research Group, Department of Kinesiology, 1280 Main Street West, McMaster University, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 31:557-64. 2006....
Neuromuscular adaptations in human muscle following low intensity resistance training with vascular occlusionDaniel R Moore
Department of Kinesiology, Exercise and Metabolism Research Group, McMaster University, 1280 Main St. W, Hamilton, Ontario, L8S 4K1, Canada
Eur J Appl Physiol 92:399-406. 2004....
Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverageSarah B Wilkinson
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
Am J Clin Nutr 85:1031-40. 2007..Proteins from different sources may differ in their ability to support muscle protein accretion because of different patterns of postprandial hyperaminoacidemia...
Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training-induced muscle hypertrophy nor strength of the elbow flexorsDaniel W D West
Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, Hamilton, ON L8S4K1 Canada
J Appl Physiol 108:60-7. 2010..We conclude that exposure of loaded muscle to acute exercise-induced elevations in endogenous anabolic hormones enhances neither muscle hypertrophy nor strength with resistance training in young men...
Resistance training alters the response of fed state mixed muscle protein synthesis in young menJason E Tang
Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 294:R172-8. 2008..01). We conclude that resistance training attenuates the protein synthetic response to acute resistance exercise, despite higher initial increases in FSR, by shortening the duration for which protein synthesis is elevated...
Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humansKirsten A Burgomaster
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Physiol 586:151-60. 2008....
A critical examination of dietary protein requirements, benefits, and excesses in athletesStuart M Phillips
Dept of Kinesiology, McMaster University, Hamilton, ON, Canada
Int J Sport Nutr Exerc Metab 17:S58-76. 2007....
Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differencesNicholas A Burd
Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, 1280 Main St, West Hamilton, ON, Canada L8S 4K1
J Appl Physiol 106:1692-701. 2009..Furthermore, we examine the underlying anabolic signaling pathways and molecules that regulate these processes...
Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal womenAndrea R Josse
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
J Nutr 141:1626-34. 2011..Therefore, diet- and exercise-induced weight loss with higher protein and increased dairy product intakes promotes more favorable body composition changes in women characterized by greater total and visceral fat loss and lean mass gain...
Short-term unilateral leg immobilization alters peripheral but not central arterial structure and function in healthy young humansMark Rakobowchuk
Department of Kinesiology, McMaster University, Hamilton, ON, Canada
Eur J Appl Physiol 111:203-10. 2011....
Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscleSarah B Wilkinson
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
J Physiol 586:3701-17. 2008....
Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exerciseDaniel W D West
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
Am J Clin Nutr 94:795-803. 2011..Direct comparisons of the effects of contrasting absorption rates exhibited by these proteins are confounded by their differing amino acid contents...
Diets higher in dairy foods and dietary protein support bone health during diet- and exercise-induced weight loss in overweight and obese premenopausal womenAndrea R Josse
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada
J Clin Endocrinol Metab 97:251-60. 2012..Consolidation and maintenance of peak bone mass in young adulthood may be compromised by inactivity, low dietary calcium, and diet-induced weight loss...
Variability in estimating eccentric contraction-induced muscle damage and inflammation in humansLouise J Beaton
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Can J Appl Physiol 27:516-26. 2002..We conclude that eccentric contraction-induced Z-band streaming and inflammatory cell response, as detected in muscle biopsy samples from humans, is highly variable with a CV of 40-70%...
The effect of body weight-supported treadmill training on muscle morphology in an individual with chronic, motor-complete spinal cord injury: A case studyMelanie M Adams
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Spinal Cord Med 29:167-71. 2006....
Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exerciseDaniel R Moore
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Physiol 587:897-904. 2009..These data highlight the importance of measuring the synthetic response of specific muscle protein fractions when examining the effects of exercise and nutrition...
Treadmill training-induced adaptations in muscle phenotype in persons with incomplete spinal cord injuryBrian G Stewart
Department of Kinesiology, McMaster University, 1280 Main Street W, Hamilton, Ontario L8S 4K1, Canada
Muscle Nerve 30:61-8. 2004..In addition, BWST training can bring about improvements in ambulatory capacity and antiatherogenic changes in blood lipid profile...
Little change in markers of protein breakdown and oxidative stress in humans in immobilization-induced skeletal muscle atrophyElisa I Glover
Department of Kinesiology Exercise Metabolic Research Group, McMaster University, Hamilton, Ontario, Canada
Appl Physiol Nutr Metab 35:125-33. 2010....
Maximizing muscle protein anabolism: the role of protein qualityJason E Tang
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Curr Opin Clin Nutr Metab Care 12:66-71. 2009..Evidence is highlighted showing differences in the responses of MPS, and muscle protein accretion, with ingestion of milk-based and soy-based proteins in young and elderly persons...
Fasted-state skeletal muscle protein synthesis after resistance exercise is altered with trainingPaul L Kim
Department of Kinesiology, IWC AB116, McMaster University, 1280 Main Street W, Hamilton, ON, Canada L8S 4K1
J Physiol 568:283-90. 2005..In addition, resistance training modified the acute response of MPS to resistance exercise by dampening the increased synthesis of non-myofibrillar proteins while maintaining the synthesis of myofibrillar proteins...
Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractionsDaniel R Moore
Dept. of Kinesiology, Exercise Metabolism Research Group, McMaster Univ, 1280 Main St. W, Hamilton, ON, Canada L8S 4K1
Am J Physiol Endocrinol Metab 288:E1153-9. 2005..Therefore, a more rapid rise in MPS after maximal LC could translate into greater protein accretion and muscle hypertrophy during chronic resistance training utilizing maximal LC...
Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and womenArkan Abadi
Department of Pediatrics and Medicine, McMaster University, Hamilton, Ontario, Canada
PLoS ONE 4:e6518. 2009....
Nutrient interaction for optimal protein anabolism in resistance exerciseLeigh Breen
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Curr Opin Clin Nutr Metab Care 15:226-32. 2012....
Sex-based comparisons of myofibrillar protein synthesis after resistance exercise in the fed stateDaniel W D West
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Appl Physiol 112:1805-13. 2012..Interestingly, our data demonstrate that exercise-induced increases in MPS are dissociated from postexercise testosteronemia and that stimulation of MPS occurs effectively with low systemic testosterone concentrations in women...
Effect of protein, dairy components and energy balance in optimizing body compositionStuart M Phillips
Exercise Metabolism Research Group Department of Kinesiology, McMaster University, Hamilton, ON, Canada
Nestle Nutr Inst Workshop Ser 69:97-108; discussion 108-13. 2011..Available evidence suggests that each practice has a highly plausible mechanistic and growing clinical rationale in terms of efficacy in promoting fat mass loss and lean mass retention during a hypoenergetic diet...
Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humansBryon R McKay
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4L8
J Physiol 586:5549-60. 2008....
Human exercise-mediated skeletal muscle hypertrophy is an intrinsic processDaniel W D West
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Canada
Int J Biochem Cell Biol 42:1371-5. 2010....
Short-term high- vs. low-velocity isokinetic lengthening training results in greater hypertrophy of the elbow flexors in young menTim N Shepstone
Exercise of Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St. W, Hamilton, ON, Canada L8S 4K1
J Appl Physiol 98:1768-76. 2005..35 rad/s) lengthening contractions. The greater hypertrophy seen in the Fast-trained arm (study I) may be related to a greater amount of protein remodeling (Z-band streaming; study II)...
Hypertrophy with unilateral resistance exercise occurs without increases in endogenous anabolic hormone concentrationSarah B Wilkinson
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
Eur J Appl Physiol 98:546-55. 2006..In conclusion, unilateral training induced local muscle hypertrophy only in the exercised limb, which occurred in the absence of changes in systemic hormones that ostensibly play a role in muscle hypertrophy...
Exercise training increases branched-chain oxoacid dehydrogenase kinase content in human skeletal muscleKrista R Howarth
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 293:R1335-41. 2007..Biochem Mol Biol Int 44: 1211-1216, 1998)...
Sex-based differences in skeletal muscle function and morphology with short-term limb immobilizationNobuo Yasuda
Dept. of Kinesiology, McMaster Univ, Hamilton, Ontario, Canada
J Appl Physiol 99:1085-92. 2005..Furthermore, we have described an effective and safe knee immobilization method that results in reductions in quadriceps muscle strength and size...
Resistance training with vascular occlusion: metabolic adaptations in human muscleKirsten A Burgomaster
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 35:1203-8. 2003..OCC potentiated the metabolic changes, perhaps by inducing an ischemic stimulus that enhanced muscle glucose transport and adenine nucleotide catabolism after LIT, but did not augment the increases in strength...
Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exerciseMichaela C Devries
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
Am J Physiol Regul Integr Comp Physiol 291:R1120-8. 2006..001) and a greater PG utilization (P = 0.05) compared with LP women. We conclude that sex, and to a lesser extent menstrual cycle, influence glucose turnover and glycogen utilization during moderate-intensity endurance exercise...
Body composition and strength changes in women with milk and resistance exerciseAndrea R Josse
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 42:1122-30. 2010..We aimed to determine whether women consuming fat-free milk versus isoenergetic carbohydrate after resistance exercise would see augmented gains in lean mass and reductions in fat mass similar to what we observed in young men...
Contraction-induced muscle damage in humans following calcium channel blocker administrationLouise J Beaton
Department of Kinesiology (Exercise Metabolism Research Group, McMaster University, Hamilton, ON L8S 4K1, Canada
J Physiol 544:849-59. 2002..In conclusion, the reduction in desmin disruption and Z-band streaming indicates that CCB attenuated, or delayed, the contraction-induced damage to sarcomeric proteins...
Resistance exercise and nutrition to counteract muscle wastingJonathan P Little
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
Appl Physiol Nutr Metab 34:817-28. 2009....
Can body weight supported treadmill training increase bone mass and reverse muscle atrophy in individuals with chronic incomplete spinal cord injury?Lora M Giangregorio
Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada
Appl Physiol Nutr Metab 31:283-91. 2006..Although 12 months of BWSTT did not increase bone density in individuals with chronic incomplete SCI, it did not appear to decrease bone density at fracture-prone sites...
Divergent response of metabolite transport proteins in human skeletal muscle after sprint interval training and detrainingKirsten A Burgomaster
Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 292:R1970-6. 2007..05). We conclude that short-term SIT induces rapid increases in skeletal muscle oxidative capacity but has divergent effects on proteins associated with glucose, lactate, and fatty acid transport...
Higher protein during an energy deficit: muscle's guardian and fat's enemy?Stuart M Phillips
Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 40:503-4. 2008
Contraction-induced muscle damage is unaffected by vitamin E supplementationLouise J Beaton
Department of Kinesiology, McMaster University, Hamilton, ON, L8S 4K1, Canada
Med Sci Sports Exerc 34:798-805. 2002..8-fold higher serum vitamin E concentration (P < 0.01), had no affect on indices of contraction-induced muscle damage nor inflammation (macrophage infiltration) as a result of eccentrically biased muscle contractions...
Antioxidant enzyme activity is up-regulated after unilateral resistance exercise training in older adultsGianni Parise
Department of Kinesiology, McMaster University, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
Free Radic Biol Med 39:289-95. 2005..In conclusion, unilateral resistance exercise training is effective in enhancing the skeletal muscle cellular antioxidant capacity in older adults. The potential long-term benefits of these adaptations remain to be evaluated...
Differential metabolomics for quantitative assessment of oxidative stress with strenuous exercise and nutritional intervention: thiol-specific regulation of cellular metabolism with N-acetyl-L-cysteine pretreatmentRichard Lee
Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Canada
Anal Chem 82:2959-68. 2010....
Insulin and muscle protein turnover in humans: stimulatory, permissive, inhibitory, or all of the above?Stuart M Phillips
Am J Physiol Endocrinol Metab 295:E731. 2008
Contractile and nutritional regulation of human muscle growthBlake B Rasmussen
Department of Kinesiology, University of Southern California, Los Angeles 90089 0652, USA
Exerc Sport Sci Rev 31:127-31. 2003..The focus of this review is on the regulation of muscle anabolism in humans after resistance exercise, nutritional provision, and a combination of the two...
Effect of unilateral resistance training on arterial compliance in elderly menFleur Poelkens
Department of Physiology, University Medical Center Nijmegen, The Netherlands
Appl Physiol Nutr Metab 32:670-6. 2007..05). There were no significant changes in resting arterial blood pressure. Unilateral resistance training for 10 weeks does not alter peripheral and central arterial compliance elderly men...
