Stuart M Phillips

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi request reprint Dietary protein for athletes: from requirements to metabolic advantage
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:647-54. 2006
  2. ncbi request reprint Increased muscle oxidative potential following resistance training induced fibre hypertrophy in young men
    Jason E Tang
    Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:495-501. 2006
  3. doi request reprint Dietary protein requirements and adaptive advantages in athletes
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton ON, Canada, L8S 4K1
    Br J Nutr 108:S158-67. 2012
  4. pmc Daytime pattern of post-exercise protein intake affects whole-body protein turnover in resistance-trained males
    Daniel R Moore
    Nestle Research Centre, Nestec Ltd, Lausanne, Switzerland
    Nutr Metab (Lond) 9:91. 2012
  5. pmc Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men
    Yifan Yang
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St, West, Hamilton, ON, Canada, L8S 4K1
    Nutr Metab (Lond) 9:57. 2012
  6. pmc Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism
    Tyler A Churchward-Venne
    Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Nutr Metab (Lond) 9:40. 2012
  7. doi request reprint Nutrient-rich meat proteins in offsetting age-related muscle loss
    Stuart M Phillips
    McMaster University, Department of Kinesiology, Hamilton, ON, Canada
    Meat Sci 92:174-8. 2012
  8. pmc Associations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight training
    Daniel W D West
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON, L8S 4K1, Canada
    Eur J Appl Physiol 112:2693-702. 2012
  9. doi request reprint The science of muscle hypertrophy: making dietary protein count
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, Canada
    Proc Nutr Soc 70:100-3. 2011
  10. pmc Effects of capsinoid ingestion on energy expenditure and lipid oxidation at rest and during exercise
    Andrea R Josse
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
    Nutr Metab (Lond) 7:65. 2010

Collaborators

Detail Information

Publications91

  1. ncbi request reprint Dietary protein for athletes: from requirements to metabolic advantage
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:647-54. 2006
    ..A framework for understanding dietary protein intake within the context of weight loss and athletic performance is laid out...
  2. ncbi request reprint Increased muscle oxidative potential following resistance training induced fibre hypertrophy in young men
    Jason E Tang
    Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:495-501. 2006
    ..We conclude that resistance training provides a stimulus for improving muscle oxidative potential, as reflected by the increased activities of CS and beta-HAD following resistance training induced hypertrophy...
  3. doi request reprint Dietary protein requirements and adaptive advantages in athletes
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton ON, Canada, L8S 4K1
    Br J Nutr 108:S158-67. 2012
    ..An attempt will be made to distinguish between protein requirements set by data from nitrogen balance studies, and a potential adaptive 'advantage' for athletes of dietary protein in excess of the RDA...
  4. pmc Daytime pattern of post-exercise protein intake affects whole-body protein turnover in resistance-trained males
    Daniel R Moore
    Nestle Research Centre, Nestec Ltd, Lausanne, Switzerland
    Nutr Metab (Lond) 9:91. 2012
    ..abstract:..
  5. pmc Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men
    Yifan Yang
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St, West, Hamilton, ON, Canada, L8S 4K1
    Nutr Metab (Lond) 9:57. 2012
    ..abstract:..
  6. pmc Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism
    Tyler A Churchward-Venne
    Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Nutr Metab (Lond) 9:40. 2012
    ....
  7. doi request reprint Nutrient-rich meat proteins in offsetting age-related muscle loss
    Stuart M Phillips
    McMaster University, Department of Kinesiology, Hamilton, ON, Canada
    Meat Sci 92:174-8. 2012
    ..The focus of this paper is on the types of dietary protein that people might reasonably consume to offset sarcopenic muscle loss...
  8. pmc Associations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight training
    Daniel W D West
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON, L8S 4K1, Canada
    Eur J Appl Physiol 112:2693-702. 2012
    ..We report that the acute exercise-induced systemic hormonal responses of cortisol and GH are weakly correlated with resistance training-induced changes in fibre CSA and LBM (cortisol only), but not with changes in strength...
  9. doi request reprint The science of muscle hypertrophy: making dietary protein count
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, Canada
    Proc Nutr Soc 70:100-3. 2011
    ..Thus, the combined evidence suggests a strategic advantage of practising early post-exercise consumption of whey protein or dairy-based protein to promote muscle protein synthesis, net muscle protein accretion and ultimately hypertrophy...
  10. pmc Effects of capsinoid ingestion on energy expenditure and lipid oxidation at rest and during exercise
    Andrea R Josse
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
    Nutr Metab (Lond) 7:65. 2010
    ..We aimed to determine how ingestion of capsinoids affected energy expenditure, lipid oxidation and blood metabolites at rest and during moderate intensity exercise...
  11. doi request reprint Uncomplicated resistance training and health-related outcomes: evidence for a public health mandate
    Stuart M Phillips
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Curr Sports Med Rep 9:208-13. 2010
    ..We propose a more feasible and easier-to-adhere-to paradigm for RT that could affect how RT is viewed and adopted as a prescription for public health...
  12. ncbi request reprint The role of milk- and soy-based protein in support of muscle protein synthesis and muscle protein accretion in young and elderly persons
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    J Am Coll Nutr 28:343-54. 2009
    ..This review focuses on evidence showing the differences in responses of MPS, and ultimately muscle protein accretion, to consumption of milk- and soy-based supplemental protein sources in humans...
  13. doi request reprint Alterations of protein turnover underlying disuse atrophy in human skeletal muscle
    S M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Appl Physiol (1985) 107:645-54. 2009
    ..Thus the normal diurnal fasted-to-fed cycle of protein balance is disrupted and, by default, proteolysis becomes dominant but is not enhanced...
  14. doi request reprint Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects)
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 34:403-10. 2009
    ..What is less well understood is how the intensity and volume of the resistance exercise stimulus is sufficient to result in rises in MPS. Recent advances in this area are discussed here, with a focus on human in vivo data...
  15. doi request reprint Resistance exercise and strong healthy children: safe when done right!
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St W, Hamilton, ON L8S4K1, Canada
    Appl Physiol Nutr Metab 33:545-6. 2008
    ..This is an understudied area that is still lacking in key areas of research to establish efficacy, dose-response relationships, and other health benefits...
  16. pmc Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humans
    Nicholas A Burd
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Nutr Metab (Lond) 8:15. 2011
    ..abstract:..
  17. pmc Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing
    Leigh Breen
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Nutr Metab (Lond) 8:68. 2011
    ..Resistance exercise combined with amino acid ingestion elicits the greatest anabolic response and may assist elderly in producing a 'youthful' muscle protein synthetic response provided sufficient protein is ingested following exercise...
  18. ncbi request reprint Dietary protein to support anabolism with resistance exercise in young men
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1 Canada
    J Am Coll Nutr 24:134S-139S. 2005
    ....
  19. doi request reprint Dietary protein for athletes: from requirements to optimum adaptation
    Stuart M Phillips
    Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada
    J Sports Sci 29:S29-38. 2011
    ..Elevated protein consumption, as high as 1.8-2.0 g · kg(-1) · day(-1) depending on the caloric deficit, may be advantageous in preventing lean mass losses during periods of energy restriction to promote fat loss...
  20. ncbi request reprint Resistance exercise: good for more than just Grandma and Grandpa's muscles
    Stuart M Phillips
    Exercise Metabolism Research Group, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1
    Appl Physiol Nutr Metab 32:1198-205. 2007
    ....
  21. ncbi request reprint Protein requirements and supplementation in strength sports
    Stuart M Phillips
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Nutrition 20:689-95. 2004
    ..Strength-trained athletes should consume protein consistent with general population guidelines, or 12% to 15% of energy from protein...
  22. ncbi request reprint Body-weight-support treadmill training improves blood glucose regulation in persons with incomplete spinal cord injury
    Stuart M Phillips
    Department of Kinesiology, Exercise and Metabolism Research Group, Centre for Health Promotion and Rehabilitation, McMaster University, 1280 Main St West, Hamilton, ON, Canada L8S 4K1
    J Appl Physiol (1985) 97:716-24. 2004
    ..Increases in the capacity for transport and phosphorylation glucose in skeletal muscle likely play a role in these adaptations...
  23. pmc Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men
    Nicholas A Burd
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    J Physiol 588:3119-30. 2010
    ..These data suggest that 3SET of resistance exercise is more anabolic than 1SET and may lead to greater increases in myofibrillar protein accretion over time...
  24. doi request reprint Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men
    Elisa I Glover
    Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, 1280 Main St West, Hamilton, ON, Canada L8S 4K1
    Am J Physiol Regul Integr Comp Physiol 295:R604-10. 2008
    ..We conclude that resistance exercise potentiates the effect of feeding on the phosphorylation and presumably activation of critical proteins involved in the regulation of muscle protein synthesis in young men...
  25. doi request reprint Carbohydrate does not augment exercise-induced protein accretion versus protein alone
    Aaron W Staples
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 43:1154-61. 2011
    ..We tested the thesis that CHO and protein coingestion would augment muscle protein synthesis (MPS) and inhibit muscle protein breakdown (MPB) at rest and after resistance exercise...
  26. pmc Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
    Elisa I Glover
    Department of Kinesiology Exercise Metabolism Research Group, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    J Physiol 586:6049-61. 2008
    ..The immobilization-induced decline in post-absorptive MPS with the 'anabolic resistance' to amino acids can account for much of immobilization-induced muscle atrophy...
  27. doi request reprint Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men
    Yifan Yang
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
    Br J Nutr 108:1780-8. 2012
    ..These data suggest that, in contrast to younger adults, in whom post-exercise rates of MPS are saturated with 20 g of protein, exercised muscles of older adults respond to higher protein doses...
  28. doi request reprint Coingestion of protein with carbohydrate during recovery from endurance exercise stimulates skeletal muscle protein synthesis in humans
    Krista R Howarth
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Appl Physiol (1985) 106:1394-402. 2009
    ..However, adding protein or additional CHO to a feeding strategy that provided 1.2 g CHO x kg(-1) x h(-1) did not further enhance glycogen resynthesis during recovery...
  29. ncbi request reprint Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters
    Joseph W Hartman
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Am J Clin Nutr 86:373-81. 2007
    ..Acute consumption of fat-free fluid milk after resistance exercise promotes a greater positive protein balance than does soy protein...
  30. doi request reprint Two weeks of reduced activity decreases leg lean mass and induces "anabolic resistance" of myofibrillar protein synthesis in healthy elderly
    Leigh Breen
    Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1
    J Clin Endocrinol Metab 98:2604-12. 2013
    ..During periods of muscle disuse, muscle protein synthesis is blunted, and muscle atrophy occurs in young and old. The impact of a short reduction in physical activity on muscle protein metabolism in older adults is unknown...
  31. doi request reprint Sex-based comparisons of myofibrillar protein synthesis after resistance exercise in the fed state
    Daniel W D West
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Appl Physiol (1985) 112:1805-13. 2012
    ..Interestingly, our data demonstrate that exercise-induced increases in MPS are dissociated from postexercise testosteronemia and that stimulation of MPS occurs effectively with low systemic testosterone concentrations in women...
  32. pmc Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men
    Tyler A Churchward-Venne
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Physiol 590:2751-65. 2012
    ....
  33. doi request reprint Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men
    Nicholas A Burd
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    Br J Nutr 108:958-62. 2012
    ..This result is probably related to a greater hyperaminoacidaemia or leucinaemia with whey ingestion...
  34. pmc Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men
    Nicholas A Burd
    McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1
    J Physiol 590:351-62. 2012
    ....
  35. doi request reprint Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young men
    Nicholas A Burd
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    J Nutr 141:568-73. 2011
    ..Our results suggest that resistance exercise performed until failure confers a sensitizing effect on human skeletal muscle for at least 24 h that is specific to the myofibrillar protein fraction...
  36. pmc Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men
    Nicholas A Burd
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 5:e12033. 2010
    ..We aimed to determine the effect of resistance exercise intensity (%1 repetition maximum-1RM) and volume on muscle protein synthesis, anabolic signaling, and myogenic gene expression...
  37. doi request reprint Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise
    Jason E Tang
    Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    J Nutr 141:195-200. 2011
    ..Furthermore, arginine does not enhance mixed or myofibrillar MPS either at rest or after resistance exercise beyond that achieved by feeding alone...
  38. ncbi request reprint Addition of glutamine to essential amino acids and carbohydrate does not enhance anabolism in young human males following exercise
    Sarah B Wilkinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:518-29. 2006
    ..The addition of glutamine to a CHO + EAA beverage had no effect on post-exercise muscle glycogen resynthesis or muscle protein synthesis, but may suppress a rise in whole-body proteolysis during the later stages of recovery...
  39. ncbi request reprint Resistance training reduces fasted- and fed-state leucine turnover and increases dietary nitrogen retention in previously untrained young men
    Daniel R Moore
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Nutr 137:985-91. 2007
    ..The increase in nitrogen balance after training demonstrates a more efficient utilization of dietary nitrogen, suggesting that protein requirements for novice weightlifters are not elevated...
  40. doi request reprint Low-volume resistance exercise attenuates the decline in strength and muscle mass associated with immobilization
    Bryan R Oates
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
    Muscle Nerve 42:539-46. 2010
    ..01). A minimal volume (140 contractions in 14 days) of resistive exercise is an effective countermeasure against immobilization-induced atrophy of the quadriceps femoris but is only partially effective for the triceps surae...
  41. pmc Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men
    Daniel W D West
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    J Physiol 587:5239-47. 2009
    ..Local mechanisms are likely to be of predominant importance for the post-exercise increase in MPS...
  42. doi request reprint Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men
    Daniel R Moore
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
    Am J Clin Nutr 89:161-8. 2009
    ..The anabolic effect of resistance exercise is enhanced by the provision of dietary protein...
  43. ncbi request reprint Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men
    Jason E Tang
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 32:1132-8. 2007
    ....
  44. doi request reprint Dose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men
    Meghann J Robinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 38:120-5. 2013
    ..An isolated bout of resistance exercise was potent in stimulating myofibrillar MPS, and acted additively with feeding...
  45. pmc Resistance exercise load does not determine training-mediated hypertrophic gains in young men
    Cameron J Mitchell
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster Univ, 1280 Main St, West, Hamilton, Ontario, L8S4L8, Canada
    J Appl Physiol (1985) 113:71-7. 2012
    ..In accordance with our previous acute measurements of muscle protein synthetic rates a lower load lifted to failure resulted in similar hypertrophy as a heavy load lifted to failure...
  46. ncbi request reprint Neuromuscular adaptations in human muscle following low intensity resistance training with vascular occlusion
    Daniel R Moore
    Department of Kinesiology, Exercise and Metabolism Research Group, McMaster University, 1280 Main St W, Hamilton, Ontario, L8S 4K1, Canada
    Eur J Appl Physiol 92:399-406. 2004
    ....
  47. ncbi request reprint Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage
    Sarah B Wilkinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
    Am J Clin Nutr 85:1031-40. 2007
    ..Proteins from different sources may differ in their ability to support muscle protein accretion because of different patterns of postprandial hyperaminoacidemia...
  48. doi request reprint Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men
    Jason E Tang
    Department of Kinesiology Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    J Appl Physiol (1985) 107:987-92. 2009
    ..These differences may be related to how quickly the proteins are digested (i.e., fast vs. slow) or possibly to small differences in leucine content of each protein...
  49. ncbi request reprint Resistance training reduces whole-body protein turnover and improves net protein retention in untrained young males
    Joseph W Hartman
    Exercise Metabolism Research Group, Department of Kinesiology, 1280 Main Street West, McMaster University, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:557-64. 2006
    ....
  50. pmc Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training-induced muscle hypertrophy nor strength of the elbow flexors
    Daniel W D West
    Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, Hamilton, ON L8S4K1 Canada
    J Appl Physiol (1985) 108:60-7. 2010
    ..We conclude that exposure of loaded muscle to acute exercise-induced elevations in endogenous anabolic hormones enhances neither muscle hypertrophy nor strength with resistance training in young men...
  51. pmc Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans
    Kirsten A Burgomaster
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Physiol 586:151-60. 2008
    ....
  52. ncbi request reprint Resistance training alters the response of fed state mixed muscle protein synthesis in young men
    Jason E Tang
    Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 294:R172-8. 2008
    ..01). We conclude that resistance training attenuates the protein synthetic response to acute resistance exercise, despite higher initial increases in FSR, by shortening the duration for which protein synthesis is elevated...
  53. pmc Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
    Sarah B Wilkinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4K1
    J Physiol 586:3701-17. 2008
    ....
  54. ncbi request reprint A critical examination of dietary protein requirements, benefits, and excesses in athletes
    Stuart M Phillips
    Dept of Kinesiology, McMaster University, Hamilton, ON, Canada
    Int J Sport Nutr Exerc Metab 17:S58-76. 2007
    ....
  55. doi request reprint Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences
    Nicholas A Burd
    Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, 1280 Main St, West Hamilton, ON, Canada L8S 4K1
    J Appl Physiol (1985) 106:1692-701. 2009
    ..Furthermore, we examine the underlying anabolic signaling pathways and molecules that regulate these processes...
  56. pmc Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women
    Andrea R Josse
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    J Nutr 141:1626-34. 2011
    ..Therefore, diet- and exercise-induced weight loss with higher protein and increased dairy product intakes promotes more favorable body composition changes in women characterized by greater total and visceral fat loss and lean mass gain...
  57. doi request reprint Short-term unilateral leg immobilization alters peripheral but not central arterial structure and function in healthy young humans
    Mark Rakobowchuk
    Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Eur J Appl Physiol 111:203-10. 2011
    ....
  58. doi request reprint Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise
    Daniel W D West
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
    Am J Clin Nutr 94:795-803. 2011
    ..Direct comparisons of the effects of contrasting absorption rates exhibited by these proteins are confounded by their differing amino acid contents...
  59. doi request reprint Resistance exercise order does not determine postexercise delivery of testosterone, growth hormone, and IGF-1 to skeletal muscle
    Daniel W D West
    Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 38:220-6. 2013
    ..001), net exposure was similar. The anabolic potential of postexercise hormones was not affected by exercise order...
  60. ncbi request reprint Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions
    Daniel R Moore
    Dept of Kinesiology, Exercise Metabolism Research Group, McMaster Univ, 1280 Main St W, Hamilton, ON, Canada L8S 4K1
    Am J Physiol Endocrinol Metab 288:E1153-9. 2005
    ..Therefore, a more rapid rise in MPS after maximal LC could translate into greater protein accretion and muscle hypertrophy during chronic resistance training utilizing maximal LC...
  61. doi request reprint Diets higher in dairy foods and dietary protein support bone health during diet- and exercise-induced weight loss in overweight and obese premenopausal women
    Andrea R Josse
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada
    J Clin Endocrinol Metab 97:251-60. 2012
    ..Consolidation and maintenance of peak bone mass in young adulthood may be compromised by inactivity, low dietary calcium, and diet-induced weight loss...
  62. pmc Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
    Daniel R Moore
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Physiol 587:897-904. 2009
    ..These data highlight the importance of measuring the synthetic response of specific muscle protein fractions when examining the effects of exercise and nutrition...
  63. pmc The effect of body weight-supported treadmill training on muscle morphology in an individual with chronic, motor-complete spinal cord injury: A case study
    Melanie M Adams
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    J Spinal Cord Med 29:167-71. 2006
    ....
  64. ncbi request reprint Variability in estimating eccentric contraction-induced muscle damage and inflammation in humans
    Louise J Beaton
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Can J Appl Physiol 27:516-26. 2002
    ..We conclude that eccentric contraction-induced Z-band streaming and inflammatory cell response, as detected in muscle biopsy samples from humans, is highly variable with a CV of 40-70%...
  65. ncbi request reprint Treadmill training-induced adaptations in muscle phenotype in persons with incomplete spinal cord injury
    Brian G Stewart
    Department of Kinesiology, McMaster University, 1280 Main Street W, Hamilton, Ontario L8S 4K1, Canada
    Muscle Nerve 30:61-8. 2004
    ..In addition, BWST training can bring about improvements in ambulatory capacity and antiatherogenic changes in blood lipid profile...
  66. doi request reprint Maximizing muscle protein anabolism: the role of protein quality
    Jason E Tang
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 12:66-71. 2009
    ..Evidence is highlighted showing differences in the responses of MPS, and muscle protein accretion, with ingestion of milk-based and soy-based proteins in young and elderly persons...
  67. pmc Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women
    Arkan Abadi
    Department of Pediatrics and Medicine, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 4:e6518. 2009
    ....
  68. pmc Fasted-state skeletal muscle protein synthesis after resistance exercise is altered with training
    Paul L Kim
    Department of Kinesiology, IWC AB116, McMaster University, 1280 Main Street W, Hamilton, ON, Canada L8S 4K1
    J Physiol 568:283-90. 2005
    ..In addition, resistance training modified the acute response of MPS to resistance exercise by dampening the increased synthesis of non-myofibrillar proteins while maintaining the synthesis of myofibrillar proteins...
  69. doi request reprint Little change in markers of protein breakdown and oxidative stress in humans in immobilization-induced skeletal muscle atrophy
    Elisa I Glover
    Department of Kinesiology Exercise Metabolic Research Group, McMaster University, Hamilton, Ontario, Canada
    Appl Physiol Nutr Metab 35:125-33. 2010
    ....
  70. doi request reprint Nutrient interaction for optimal protein anabolism in resistance exercise
    Leigh Breen
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Clin Nutr Metab Care 15:226-32. 2012
    ....
  71. doi request reprint Effect of protein, dairy components and energy balance in optimizing body composition
    Stuart M Phillips
    Exercise Metabolism Research Group Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Nestle Nutr Inst Workshop Ser 69:97-108; discussion 108-13. 2011
    ..Available evidence suggests that each practice has a highly plausible mechanistic and growing clinical rationale in terms of efficacy in promoting fat mass loss and lean mass retention during a hypoenergetic diet...
  72. doi request reprint Human exercise-mediated skeletal muscle hypertrophy is an intrinsic process
    Daniel W D West
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Canada
    Int J Biochem Cell Biol 42:1371-5. 2010
    ....
  73. ncbi request reprint Exercise training increases branched-chain oxoacid dehydrogenase kinase content in human skeletal muscle
    Krista R Howarth
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 293:R1335-41. 2007
    ..Biochem Mol Biol Int 44: 1211-1216, 1998)...
  74. ncbi request reprint Short-term high- vs. low-velocity isokinetic lengthening training results in greater hypertrophy of the elbow flexors in young men
    Tim N Shepstone
    Exercise of Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St W, Hamilton, ON, Canada L8S 4K1
    J Appl Physiol 98:1768-76. 2005
    ..35 rad/s) lengthening contractions. The greater hypertrophy seen in the Fast-trained arm (study I) may be related to a greater amount of protein remodeling (Z-band streaming; study II)...
  75. pmc Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans
    Bryon R McKay
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4L8
    J Physiol 586:5549-60. 2008
    ....
  76. ncbi request reprint Hypertrophy with unilateral resistance exercise occurs without increases in endogenous anabolic hormone concentration
    Sarah B Wilkinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Eur J Appl Physiol 98:546-55. 2006
    ..In conclusion, unilateral training induced local muscle hypertrophy only in the exercised limb, which occurred in the absence of changes in systemic hormones that ostensibly play a role in muscle hypertrophy...
  77. ncbi request reprint Menstrual cycle phase and sex influence muscle glycogen utilization and glucose turnover during moderate-intensity endurance exercise
    Michaela C Devries
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
    Am J Physiol Regul Integr Comp Physiol 291:R1120-8. 2006
    ..001) and a greater PG utilization (P = 0.05) compared with LP women. We conclude that sex, and to a lesser extent menstrual cycle, influence glucose turnover and glycogen utilization during moderate-intensity endurance exercise...
  78. ncbi request reprint Resistance training with vascular occlusion: metabolic adaptations in human muscle
    Kirsten A Burgomaster
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 35:1203-8. 2003
    ..g., 22, 25). The OCC stress might be expected to induce metabolic alterations that are consistent with compromised oxygen delivery rather than an increase in strength per se, but this has not been studied...
  79. ncbi request reprint Sex-based differences in skeletal muscle function and morphology with short-term limb immobilization
    Nobuo Yasuda
    Dept of Kinesiology, McMaster Univ, Hamilton, Ontario, Canada
    J Appl Physiol 99:1085-92. 2005
    ..Furthermore, we have described an effective and safe knee immobilization method that results in reductions in quadriceps muscle strength and size...
  80. doi request reprint Body composition and strength changes in women with milk and resistance exercise
    Andrea R Josse
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 42:1122-30. 2010
    ..We aimed to determine whether women consuming fat-free milk versus isoenergetic carbohydrate after resistance exercise would see augmented gains in lean mass and reductions in fat mass similar to what we observed in young men...
  81. pmc Contraction-induced muscle damage in humans following calcium channel blocker administration
    Louise J Beaton
    Department of Kinesiology Exercise Metabolism Research Group, McMaster University, Hamilton, ON L8S 4K1, Canada
    J Physiol 544:849-59. 2002
    ..In conclusion, the reduction in desmin disruption and Z-band streaming indicates that CCB attenuated, or delayed, the contraction-induced damage to sarcomeric proteins...
  82. doi request reprint Resistance exercise and nutrition to counteract muscle wasting
    Jonathan P Little
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Appl Physiol Nutr Metab 34:817-28. 2009
    ....
  83. ncbi request reprint Can body weight supported treadmill training increase bone mass and reverse muscle atrophy in individuals with chronic incomplete spinal cord injury?
    Lora M Giangregorio
    Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada
    Appl Physiol Nutr Metab 31:283-91. 2006
    ..Although 12 months of BWSTT did not increase bone density in individuals with chronic incomplete SCI, it did not appear to decrease bone density at fracture-prone sites...
  84. ncbi request reprint Divergent response of metabolite transport proteins in human skeletal muscle after sprint interval training and detraining
    Kirsten A Burgomaster
    Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, Hamilton, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 292:R1970-6. 2007
    ..05). We conclude that short-term SIT induces rapid increases in skeletal muscle oxidative capacity but has divergent effects on proteins associated with glucose, lactate, and fatty acid transport...
  85. ncbi request reprint Contraction-induced muscle damage is unaffected by vitamin E supplementation
    Louise J Beaton
    Department of Kinesiology, McMaster University, Hamilton, ON, L8S 4K1, Canada
    Med Sci Sports Exerc 34:798-805. 2002
    ..The present study sought to determine the effect of vitamin E supplementation on indices of exercise-induced muscle damage and the postexercise inflammatory response after performance of repeated eccentric muscle contractions...
  86. ncbi request reprint Antioxidant enzyme activity is up-regulated after unilateral resistance exercise training in older adults
    Gianni Parise
    Department of Kinesiology, McMaster University, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Free Radic Biol Med 39:289-95. 2005
    ..In conclusion, unilateral resistance exercise training is effective in enhancing the skeletal muscle cellular antioxidant capacity in older adults. The potential long-term benefits of these adaptations remain to be evaluated...
  87. ncbi request reprint Higher protein during an energy deficit: muscle's guardian and fat's enemy?
    Stuart M Phillips
    Department of Kinesiology, Exercise Metabolism Research Group, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 40:503-4. 2008
  88. doi request reprint Differential metabolomics for quantitative assessment of oxidative stress with strenuous exercise and nutritional intervention: thiol-specific regulation of cellular metabolism with N-acetyl-L-cysteine pretreatment
    Richard Lee
    Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Canada
    Anal Chem 82:2959-68. 2010
    ....
  89. ncbi request reprint Insulin and muscle protein turnover in humans: stimulatory, permissive, inhibitory, or all of the above?
    Stuart M Phillips
    Am J Physiol Endocrinol Metab 295:E731. 2008
  90. ncbi request reprint Contractile and nutritional regulation of human muscle growth
    Blake B Rasmussen
    Department of Kinesiology, University of Southern California, Los Angeles 90089 0652, USA
    Exerc Sport Sci Rev 31:127-31. 2003
    ..The focus of this review is on the regulation of muscle anabolism in humans after resistance exercise, nutritional provision, and a combination of the two...
  91. ncbi request reprint Effect of unilateral resistance training on arterial compliance in elderly men
    Fleur Poelkens
    Department of Physiology, University Medical Center Nijmegen, The Netherlands
    Appl Physiol Nutr Metab 32:670-6. 2007
    ..05). There were no significant changes in resting arterial blood pressure. Unilateral resistance training for 10 weeks does not alter peripheral and central arterial compliance elderly men...