Christopher PattersonSummaryAffiliation: McMaster University Country: Canada Publications
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Detail Information
Publications
Brain type carnosinase in dementia: a pilot studyCynthia M Balion
Department of Laboratory Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada
BMC Neurol 7:38. 2007..Carnosinase is a dipeptidase found almost exclusively in brain and serum. Carnosinase and its substrate carnosine have been linked to neuropathophysiological processes...- A randomized trial of mail vs. telephone invitation to a community-based cardiovascular health awareness program for older family practice patients [ISRCTN61739603]Tina Karwalajtys
Department of Family Medicine, McMaster University, Hamilton, Canada
BMC Fam Pract 6:35. 2005.... - Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer diseaseChristopher Patterson
Division of Geriatric Medicine, McMaster University, Hamilton, Ont
CMAJ 178:548-56. 2008.... 
Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guidelineParminder Raina
McMaster University, Hamilton, Ontario, Canada
Ann Intern Med 148:379-97. 2008..The effectiveness of the 5 U.S. Food and Drug Administration-approved pharmacologic therapies for dementias in achieving clinically relevant improvements is unclear...- Blood inflammatory markers and risk of dementia: The Conselice Study of Brain AgingGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, 40138 Bologna, Italy
Neurobiol Aging 28:1810-20. 2007..91; 95%CI, 1.02-3.56) but not VaD risk. Blood inflammatory markers are associated with increased VaD risk but do not predict AD, which seems selectively associated with hyperhomocysteinemia... - Progress in clinical neurosciences: Treatment of Alzheimer's disease and other dementias--review and comparison of the cholinesterase inhibitorsDavid B Hogan
Department of Medicine, University of Calgary, Calgary. Alberta, Canada
Can J Neurol Sci 29:306-14. 2002..We view all three available cholinesterase inhibitors as first-line drugs... 
Development of an easy prognostic score for frailty outcomes in the agedGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Italy
Age Ageing 37:161-6. 2008..identification of frailty is recommended in geriatric practice. However, there is a lack of frailty scores combining easy-to-collect predictors from multiple domains...- Endogenous sex hormones as risk factors for dementia in elderly men and womenGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola, Malpighi, Via Massarenti, 9 40138 Bologna, Italy
J Gerontol A Biol Sci Med Sci 62:1035-41. 2007..The associations of endogenous sex hormones with risk of dementia in the elderly population are not well known... - Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderlyGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital S Orsola Malpighi, Bologna, Italy
Am J Clin Nutr 84:1473-80. 2006..Homocysteine, another risk factor for vascular disease and dementia, also binds to VLDL in blood. However, the association between APOE4 and hyperhomocysteinemia has never been thoroughly investigated... - Metabolic Syndrome: prevalence and prediction of mortality in elderly individualsGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University of Bologna, Via Massarenti, 9 40138 Bologna, Italy
Diabetes Care 29:2471-6. 2006.... - Translating evidence into practice: the case of dementia guidelines in specialized geriatric servicesDavid L Lewis
Regional Geriatrics Program Central, 88 Maplewood Avenue, Hamilton, ON, L8M 1W9, Canada
Can J Aging 24:251-60. 2005..Outcomes of the process included a resource manual, a network of practitioners, and action recommendations based upon survey data. An early follow-up evaluation showed increased adoption of guidelines... - Association of European population levels of thrombotic and inflammatory factors with risk of coronary heart disease: the MONICA Optional Haemostasis StudyJohn Yarnell
Department of Epidemiology and Public Health, Queen s University of Belfast, UK
Eur Heart J 26:332-42; discussion 317-8. 2005..We therefore measured thrombotic and inflammatory markers in a substudy of the WHO MONICA project and correlated these with CHD event rates... - Comparison studies of cholinesterase inhibitors for Alzheimer's diseaseDavid B Hogan
Division of Geriatric Medicine, University of Calgary, Calgary, Alberta, Canada
Lancet Neurol 3:622-6. 2004..Between 27% and 55% of CONSORT items per study were rated as inadequately reported. The methodological limitations of these studies reduce our confidence in the validity of the conclusions drawn in the published reports... - Plasma tocopherols and risk of cognitive impairment in an elderly Italian cohortGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology, and Hepatology, University Hospital Sant Orsola Malpighi, University of Bologna, Bologna, Italy
Am J Clin Nutr 87:1306-13. 2008..The most abundant and most investigated form of vitamin E in humans is alpha-tocopherol, but other antioxidant tocopherols (beta, gamma, and delta) exist in nature...