A Papaioannou

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. pmc Improving care after hip fracture: the fracture? Think osteoporosis (FTOP) program
    Naomi Dore
    Hamilton Health Sciences St, Peter s Hospital, 88 Maplewood Avenue, Hamilton, ON L8M 1W9, Canada
    BMC Geriatr 13:130. 2013
  2. pmc Efficacy of vitamin D supplementation in depression in adults: a systematic review protocol
    Guowei Li
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada
    Syst Rev 2:64. 2013
  3. pmc An interdisciplinary knowledge translation intervention in long-term care: study protocol for the vitamin D and osteoporosis study (ViDOS) pilot cluster randomized controlled trial
    Courtney C Kennedy
    Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
    Implement Sci 7:48. 2012
  4. pmc Changes in trabecular bone microarchitecture in postmenopausal women with and without type 2 diabetes: a two year longitudinal study
    Janet M Pritchard
    Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    BMC Musculoskelet Disord 14:114. 2013
  5. pmc Brain type carnosinase in dementia: a pilot study
    Cynthia M Balion
    Department of Laboratory Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada
    BMC Neurol 7:38. 2007
  6. pmc The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women
    Robert B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 12:209. 2011
  7. pmc Improvement in health-related quality of life in osteoporosis patients treated with teriparatide
    Arthur N Lau
    Division of Rheumatology and Department of Medicine, St, Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 9:151. 2008
  8. pmc Optimizing care in osteoporosis: the Canadian quality circle project
    George Ioannidis
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 9:130. 2008
  9. pmc Evaluation of easily measured risk factors in the prediction of osteoporotic fractures
    Robert Bensen
    Medical Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 6:47. 2005
  10. pmc Osteoporosis in Canadian adult cystic fibrosis patients: a descriptive study
    Christine Brenckmann
    Department of Community Health and Epidemiology, Dalhousie University, Halifax, B3H 4H7, Canada
    BMC Musculoskelet Disord 4:13. 2003

Detail Information

Publications109 found, 100 shown here

  1. pmc Improving care after hip fracture: the fracture? Think osteoporosis (FTOP) program
    Naomi Dore
    Hamilton Health Sciences St, Peter s Hospital, 88 Maplewood Avenue, Hamilton, ON L8M 1W9, Canada
    BMC Geriatr 13:130. 2013
    ..This evaluation determined rates of osteoporosis treatment and bone mineral density (BMD) testing in hip fracture patients following discharge from a rehabilitation unit...
  2. pmc Efficacy of vitamin D supplementation in depression in adults: a systematic review protocol
    Guowei Li
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada
    Syst Rev 2:64. 2013
    ....
  3. pmc An interdisciplinary knowledge translation intervention in long-term care: study protocol for the vitamin D and osteoporosis study (ViDOS) pilot cluster randomized controlled trial
    Courtney C Kennedy
    Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada
    Implement Sci 7:48. 2012
    ..This protocol describes the evaluation of a multifaceted, interdisciplinary KT intervention aimed at integrating evidence-based osteoporosis and fracture prevention strategies into LTC care processes...
  4. pmc Changes in trabecular bone microarchitecture in postmenopausal women with and without type 2 diabetes: a two year longitudinal study
    Janet M Pritchard
    Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    BMC Musculoskelet Disord 14:114. 2013
    ..The aim of this study was to compare two year changes in trabecular bone microarchitecture in women with and without type 2 diabetes...
  5. pmc Brain type carnosinase in dementia: a pilot study
    Cynthia M Balion
    Department of Laboratory Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada
    BMC Neurol 7:38. 2007
    ..Carnosinase is a dipeptidase found almost exclusively in brain and serum. Carnosinase and its substrate carnosine have been linked to neuropathophysiological processes...
  6. pmc The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women
    Robert B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 12:209. 2011
    ..The purpose was to estimate the relative efficacy of reduction of fractures in post-menopausal women, and to assess robustness of the results...
  7. pmc Improvement in health-related quality of life in osteoporosis patients treated with teriparatide
    Arthur N Lau
    Division of Rheumatology and Department of Medicine, St, Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 9:151. 2008
    ..To determine whether patients with osteoporosis treated with teriparatide experienced improvement in HRQL and pain symptoms after several months of therapy...
  8. pmc Optimizing care in osteoporosis: the Canadian quality circle project
    George Ioannidis
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 9:130. 2008
    ....
  9. pmc Evaluation of easily measured risk factors in the prediction of osteoporotic fractures
    Robert Bensen
    Medical Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 6:47. 2005
    ..As few premonitory symptoms for fracture exist, it is of critical importance that physicians effectively and efficiently identify individuals at increased fracture risk...
  10. pmc Osteoporosis in Canadian adult cystic fibrosis patients: a descriptive study
    Christine Brenckmann
    Department of Community Health and Epidemiology, Dalhousie University, Halifax, B3H 4H7, Canada
    BMC Musculoskelet Disord 4:13. 2003
    ..Cystic fibrosis is the most common fatal autosomal recessive genetic disease in the Caucasian population. Osteoporosis is increasingly being recognised as an important complication in people with cystic fibrosis...
  11. pmc Validation of the GALS musculoskeletal screening exam for use in primary care: a pilot study
    Karen A Beattie
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    BMC Musculoskelet Disord 9:115. 2008
    ..The secondary goal was to examine the incidence of MSK disorders and assess the frequency with which new diagnoses not previously documented in patients' charts were identified...
  12. pmc Do patients perceive a link between a fragility fracture and osteoporosis?
    Lora Giangregorio
    Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada
    BMC Musculoskelet Disord 9:38. 2008
    ..To evaluate factors associated with whether patients associate their fracture with future fracture risk...
  13. pmc Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study
    Daniel T Grima
    Center for Osteoporosis and Arthritis Research and Education COARE, 1185 Rushbrooke Dr, Oakville, ON, L6 M 1H8, Canada
    BMC Musculoskelet Disord 11:68. 2010
    ..The objective of our study was to quantify changes in AE rates and BMD scores, as well as associated alendronate discontinuation among patients before and after switch from brand to generic alendronate...
  14. pmc The utilization of appropriate osteoporosis medications improves following a multifaceted educational intervention: the Canadian quality circle project (CQC)
    George Ioannidis
    Department of Medicine, McMaster University, Hamilton, Canada
    BMC Med Educ 9:54. 2009
    ..However, appropriate therapy utilization of the disease remains suboptimal. Thus, the objective of the study was to change physicians' therapy administration behavior in accordance with the Osteoporosis Canada 2002 guidelines...
  15. pmc Quality of anticoagulation and use of warfarin-interacting medications in long-term care: a chart review
    Madeleine Verhovsek
    McMaster University, Hamilton, Ontario, Canada
    BMC Geriatr 8:13. 2008
    ....
  16. pmc What are the beliefs, attitudes and practices of front-line staff in long-term care (LTC) facilities related to osteoporosis awareness, management and fracture prevention?
    Arthur N Lau
    Division of Rheumatology and Department of Medicine, St, Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    BMC Geriatr 10:73. 2010
    ..A secondary question assessed was the nurse's and PSW's attitudes and beliefs regarding the role and benefits of vitamin D for LTC patients...
  17. pmc Closing the osteoporosis care gap: increased osteoporosis awareness among geriatrics and rehabilitation teams
    Derek A Haaland
    McMaster University, Department of Medicine, Main Street West, Hamilton, Ontario, Canada
    BMC Geriatr 9:28. 2009
    ....
  18. pmc A randomized controlled trial of vitamin D dosing strategies after acute hip fracture: no advantage of loading doses over daily supplementation
    Alexandra Papaioannou
    McMaster University, HHSC, St Peter s Hospital Juravinski Research Centre, 88 Maplewood Avenue Hamilton, ON L8M 1W9, Canada
    BMC Musculoskelet Disord 12:135. 2011
    ..The primary aim of our study was to examine whether large loading doses in addition to daily vitamin D offered any advantage over a simple daily low-dose vitamin D regimen for increasing vitamin D levels...
  19. pmc Longitudinal analysis of vertebral fracture and BMD in a Canadian cohort of adult cystic fibrosis patients
    Alexandra Papaioannou
    Department of Medicine, McMaster University, 1200 Main St W, Hamilton ON, L8N 3Z5, Canada
    BMC Musculoskelet Disord 9:125. 2008
    ..In this study, we examined longitudinal change in bone mineral density (BMD) and the prevalence of vertebral fractures in adult CF patients, without lung-transplant, attending a Canadian specialty clinic...
  20. pmc A team-based approach to warfarin management in long term care: a feasibility study of the MEDeINR electronic decision support system
    Alexandra Papaioannou
    Department of Medicine, McMaster University, 1280 Main Street West, Hamilton L8N 3Z5, Canada
    BMC Geriatr 10:38. 2010
    ..We evaluated the MEDeINR system in a pre-post implementation design by examining the impact on INR control, testing frequency, and experiences of staff in using the system...
  21. ncbi request reprint The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study
    A Papaioannou
    Division of Geriatric Medicine, McMaster University, Hamilton Health Sciences Chedoke Site, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Osteoporos Int 19:581-7. 2008
    ..The need to treat fragility fractures is well established in guidelines, and these numbers represent an important care gap...
  22. doi request reprint The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study
    A Papaioannou
    McMaster University, Hamilton Health Sciences Chedoke Site, Hamilton, ON, Canada
    Osteoporos Int 20:703-14. 2009
    ..Incident fractures had a negative impact on HUI scores over time...
  23. doi request reprint Alendronate once weekly for the prevention and treatment of bone loss in Canadian adult cystic fibrosis patients (CFOS trial)
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton Health Sciences, Chedoke Site, Building 74, 1200 Main St West, Hamilton, ON, Canada L8N 3Z5
    Chest 134:794-800. 2008
    ..A multicenter, randomized, controlled trial was conducted to assess the efficacy, tolerability, and safety of therapy with oral alendronate (FOSAMAX; Merck; Whitehouse Station, NJ) in adults with CF and low bone mass...
  24. ncbi request reprint Risk factors for low BMD in healthy men age 50 years or older: a systematic review
    A Papaioannou
    Division of Geriatric Medicine, Department of Medicine, McMaster University, Ontario, Canada
    Osteoporos Int 20:507-18. 2009
    ..Consistent risk factors were: age, smoking, low weight, physical/functional limitations, and previous fracture. Data specific to men has clinical and policy implications...
  25. ncbi request reprint Patient adherence to osteoporosis medications: problems, consequences and management strategies
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Drugs Aging 24:37-55. 2007
    ..Future studies are needed regarding strategies to increase adherence to osteoporosis medications...
  26. ncbi request reprint Prevalence of vertebral fractures among patients with chronic obstructive pulmonary disease in Canada
    A Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 14:913-7. 2003
    ..The primary objective of this case-control study was to determine the prevalence of vertebral fractures among patients with COPD admitted to acute care compared with a gender- and age-matched control group...
  27. ncbi request reprint Efficacy of home-based exercise for improving quality of life among elderly women with symptomatic osteoporosis-related vertebral fractures
    A Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 14:677-82. 2003
    ..Home-based exercise with minimal supervision improves quality of life in elderly women with vertebral fractures. Future research is needed to determine if home exercise programs reduce falls and fall-related injuries in the elderly...
  28. ncbi request reprint Diagnosis and management of vertebral fractures in elderly adults
    Alexandra Papaioannou
    Department of Medicine, Division of Geriatric Medicine AP McMaster University, Hamilton, Ontario, Canada
    Am J Med 113:220-8. 2002
    ..There is evidence from randomized controlled trials that pharmacologic therapy can reduce the risk of future fractures by 40% to 50%. Vertebroplasty may be effective in the control of pain and in obtaining stability of the spine...
  29. pmc Prediction of falls using a risk assessment tool in the acute care setting
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    BMC Med 2:1. 2004
    ..Although the tool has several strengths, certain limitations exist which may not allow generalizability to a Canadian setting. Thus, we tested the STRATIFY tool with some modification and re-weighting of items in Canadian hospitals...
  30. pmc The osteoporosis care gap in Canada
    A Papaioannou
    Department of Medicine, McMaster University, Hamilton, Canada
    BMC Musculoskelet Disord 5:11. 2004
    ..However, the extent to which patients who fracture are assessed and treated for osteoporosis is not clear...
  31. ncbi request reprint Determinants of health-related quality of life in women with vertebral fractures
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 17:355-63. 2006
    ..We demonstrated that several modifiable factors influence HRQL in patients with vertebral fractures, and physicians should be aware of these and other markers of reduced HRQL to enhance patient care...
  32. ncbi request reprint All patients with inflammatory bowel disease should have bone density assessment: pro
    A Papaioannou
    Division of Geriatric Medicine, McMaster University, Hamilton, Ontario, Canada
    Inflamm Bowel Dis 7:158-62; discussion 168-9. 2001
    ..Given the current burden of osteoporosis, bone mineral density is recommended...
  33. ncbi request reprint The influence of osteoporotic fractures on health-related quality of life in community-dwelling men and women across Canada
    J D Adachi
    Department of Medicine, St Joseph's Hospital, McMaster University, Hamilton, Ontario Canada
    Osteoporos Int 12:903-8. 2001
    ..In conclusion, HRQL was lower in the physical functioning domain in women and the role-physical domain in men who sustained main fractures at the hip. Subclinical vertebral fractures exerted a moderate effect on HRQL...
  34. ncbi request reprint The association between osteoporotic fractures and health-related quality of life as measured by the Health Utilities Index in the Canadian Multicentre Osteoporosis Study (CaMos)
    J D Adachi
    Department of Medicine, St Joseph s Hospital, McMaster University, Charlton Avenue East, Suite 501, L8 N 1Y2 Hamilton, Ontario, Canada
    Osteoporos Int 14:895-904. 2003
    ..06; 95% CI: -0.11, -0.00) for women, and rib fractures (-0.06; 95% CI: -0.12, -0.00) for men. In conclusion, this study demonstrates a negative association between osteoporotic fractures and quality of life in both women and men...
  35. doi request reprint Fragility fractures and the osteoporosis care gap in women: the Canadian Multicentre Osteoporosis Study
    L A Fraser
    Departments of Epidemiology and Medicine, Hamilton Health Sciences Chedoke Site, McMaster University, 1200 Main Street West, Hamilton, ON L8N3Z5, Canada
    Osteoporos Int 22:789-96. 2011
    ..We found that approximately half of these women were not being treated, indicating a significant care gap in osteoporosis treatment...
  36. doi request reprint Non-hip, non-spine fractures drive healthcare utilization following a fracture: the Global Longitudinal Study of Osteoporosis in Women (GLOW)
    G Ioannidis
    St Joseph s Hospital, McMaster University, 501 25 Charlton Ave E, Hamilton, ON, L8N 1Y2, Canada
    Osteoporos Int 24:59-67. 2013
    ..Over the course of 1 year, there were five times more non-hip, non-spine fractures than hip or spine fractures, resulting in twice as many days of hospitalization and rehabilitation/nursing home care for non-hip, non-spine fractures...
  37. ncbi request reprint Health-related quality of life measurements in elderly Canadians with osteoporosis compared to other chronic medical conditions: a population-based study from the Canadian Multicentre Osteoporosis Study (CaMos)
    A M Sawka
    Division of Endocrinology and Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 16:1836-40. 2005
    ..The decrement in HUI3 score seen in participants with osteoporosis was comparable to that observed in other chronic medical conditions, such as arthritis, COPD, diabetes mellitus or heart disease...
  38. ncbi request reprint Could a policy of provision of hip protectors to elderly nursing home residents result in cost savings in acute hip fracture care? The case of Ontario, Canada
    A M Sawka
    Division of Endocrinology and Department of Medicine, University Health Network and University of Toronto, Toronto, ON, Canada
    Osteoporos Int 18:819-27. 2007
    ..In a recent meta-analysis, we determined that a strategy of provision of hip protectors decreases the risk of hip fracture in nursing home residents...
  39. pmc The burden of illness of osteoporosis in Canada
    J E Tarride
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, 25 Main Street West, Suite 2000, Hamilton, ON, L8P 1H1, Canada
    Osteoporos Int 23:2591-600. 2012
    ..3 billion in Canada or 1.3% of Canada's healthcare expenditures. Prevention of fractures in high-risk individuals is key to decrease the financial burden of osteoporosis...
  40. doi request reprint Osteoporosis risk perceptions among patients who have sustained a fragility fracture
    Lora Giangregorio
    Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada
    Patient Educ Couns 74:213-20. 2009
    ..To explore the perceptions of patients who have sustained a fragility fracture regarding their future fracture risk and the beliefs underlying their perceptions...
  41. ncbi request reprint Associations among disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results from the Canadian Multicentre Osteoporosis Study
    D A Hanley
    Department of Medicine, University of Calgary Calgary, Alberta, Canada
    J Bone Miner Res 18:784-90. 2003
    ..The importance of these associations for osteoporosis case finding and management require further and prospective studies...
  42. doi request reprint Estimating the excess costs for patients with incident fractures, prevalent fractures, and nonfracture osteoporosis
    R B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, ON, Canada
    Osteoporos Int 24:581-93. 2013
    ..Prevalent fractures also have significant excess costs that are similar in relative magnitude to asthma/chronic obstructive pulmonary disease...
  43. doi request reprint Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos
    L A Fraser
    Department of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 22:829-37. 2011
    ..The Canadian FRAX tool showed good calibration and discrimination for both hip and major osteoporotic fractures...
  44. ncbi request reprint Quantitative analysis of subchondral sclerosis of the tibia by bone texture parameters in knee radiographs: site-specific relationships with joint space width
    A K O Wong
    Department of Medical Sciences, McMaster University, Hamilton, ON, Canada
    Osteoarthritis Cartilage 17:1453-60. 2009
    ....
  45. doi request reprint Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study
    S A Jamal
    Medicine, University of Toronto, Toronto, ON, Canada
    Osteoporos Int 20:737-44. 2009
    ..Subjects reporting nitrate use had increased BMD compared with non-users, confirming that nitrates have positive BMD effects in women and men...
  46. ncbi request reprint Too Fit To Fracture: a consensus on future research priorities in osteoporosis and exercise
    L M Giangregorio
    Department of Kinesiology, University of Waterloo, 200 University Ave W, Waterloo, ON, N2L 3G1, Canada
    Osteoporos Int 25:1465-72. 2014
    ....
  47. doi request reprint Bone mineralization is elevated and less heterogeneous in adults with type 2 diabetes and osteoarthritis compared to controls with osteoarthritis alone
    J M Pritchard
    Faculty of Health Sciences, McMaster University, 1280 Main St West, Hamilton ON, Canada L8S 4K1
    Bone 54:76-82. 2013
    ..The purpose of this study was to determine whether trabecular bone mineralization differed in adults with type 2 diabetes compared to adults without type 2 diabetes...
  48. doi request reprint Estimation of the lifetime risk of hip fracture for women and men in Canada
    R B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, ON, Canada
    Osteoporos Int 23:921-7. 2012
    ..1% and 4.6%, respectively, and 8.9% and 6.7% after incorporating declining rates of hip fracture and increases in longevity...
  49. ncbi request reprint Economic implications of hip fracture: health service use, institutional care and cost in Canada
    M E Wiktorowicz
    Departments of Epidemiology and Biostatistics and Political Science, University of Western Ontario, London, Ontario, Canada
    Osteoporos Int 12:271-8. 2001
    ..Annual economic implications of hip fracture in Canada are $650 million and are expected to rise to $2.4 billion by 2041...
  50. ncbi request reprint Greater first year effectiveness drives favorable cost-effectiveness of brand risedronate versus generic or brand alendronate: modeled Canadian analysis
    D T Grima
    Cornerstone Research Group Inc, Burlington, ON, L7L 5Y6, Canada
    Osteoporos Int 19:687-97. 2008
    ..Using a published osteoporosis model, the researchers found risedronate to be cost-effective compared to generic or brand alendronate for the treatment of Canadian postmenopausal osteoporosis in patients aged 65 years or older...
  51. doi request reprint Osteoporosis knowledge among individuals with recent fragility fracture
    L Giangregorio
    Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada
    Orthop Nurs 29:99-107. 2010
    ..To evaluate osteoporosis knowledge among patients with fractures and to evaluate factors associated with osteoporosis knowledge...
  52. ncbi request reprint Rational use of oral bisphosphonates for the treatment of osteoporosis
    Julian M R Mathoo
    McMaster University, 201 25 Charlton Ave E, Hamiton, Ontario, L8N 1Y2 Canada
    Curr Osteoporos Rep 2:17-23. 2004
    ..Once-weekly dosing options with alendronate and risedronate are effective and reduce serious adverse drug effects, and therefore, are welcome additions to our therapeutic armamentarium...
  53. ncbi request reprint Adherence to bisphosphonates and hormone replacement therapy in a tertiary care setting of patients in the CANDOO database
    Alexandra Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 14:808-13. 2003
    ..In conclusion, alendronate users were more likely to discontinue therapy than etidronate users over the follow-up period. Potential barriers to long-term patient adherence to osteoporosis therapies need to be evaluated...
  54. doi request reprint The effect of proton pump inhibitors on fracture risk: report from the Canadian Multicenter Osteoporosis Study
    L A Fraser
    Department of Medicine, University of Western Ontario, London, ON, Canada
    Osteoporos Int 24:1161-8. 2013
    ..We found an increased risk of fracture in individuals who used PPIs. The risk remained after controlling for other known fracture risk factors...
  55. doi request reprint Ankle fractures do not predict osteoporotic fractures in women with or without diabetes
    J M Pritchard
    Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 23:957-62. 2012
    ..We found that a prior ankle fracture does not predict subsequent osteoporotic fractures in women with or without diabetes...
  56. ncbi request reprint Corticosteroid-Induced osteoporosis: detection and management
    J D Adachi
    Department of Medicine, St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    Drug Saf 24:607-24. 2001
    ..Given our current knowledge and the evidence that is outlined in this review, it is hoped that patients who require therapy with corticosteroids for more than 3 months will be offered appropriate preventative treatment...
  57. ncbi request reprint Lengthy hospitalization associated with vertebral fractures despite control for comorbid conditions
    A Papaioannou
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 12:870-4. 2001
    ..1 days in a 50-year-old woman. Among patients admitted for other problems, comorbid vertebral fractures added 2.1 days. These findings indicate that hospital stays for vertebral fractures are lengthy despite control for comorbidity...
  58. ncbi request reprint Are oral bisphosphonates effective in improving lumbar bone mineral density in breast cancer survivors with osteopenia or osteoporosis?
    Anna M Sawka
    Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton ON
    J Obstet Gynaecol Can 27:759-64. 2005
    ....
  59. ncbi request reprint What is the number of older Canadians needed to screen by measurement of bone density to detect an undiagnosed case of osteoporosis? a population-based study from CaMos
    Anna M Sawka
    Department of Medicine, Division of Endocrinology, University of Toronto, Toronto, Ontario, Canada
    J Clin Densitom 9:413-8. 2006
    ..9%, 97.0%; 68 of 73) were not aware of it. Thus, the minimum NNS by BMD testing to detect one previously undiagnosed case of osteoporosis in Canada is: 6 women aged >or=65 yr, 13 men aged >or=65 yr, and 10 men aged >or=70 yr...
  60. ncbi request reprint Changes to osteoporosis prevalence according to method of risk assessment
    J Brent Richards
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    J Bone Miner Res 22:228-34. 2007
    ....
  61. pmc Impact of a centralized osteoporosis coordinator on post-fracture osteoporosis management: a cluster randomized trial
    S B Jaglal
    Toronto Rehabilitation Institute, Toronto, ON, Canada
    Osteoporos Int 23:87-95. 2012
    ..Compared with controls, intervention patients were five times more likely to receive BMD testing and two times more likely to receive appropriate management...
  62. doi request reprint Osteoporosis management among residents living in long-term care
    L M Giangregorio
    Department of Kinesiology, University of Waterloo, 200 University Ave W, Waterloo, ON, N2L 3G1, Canada
    Osteoporos Int 20:1471-8. 2009
    ..g., those with >5 comorbidities, dementia, and wheelchair use. Many LTC residents who are at risk of fracture are not receiving optimal osteoporosis management...
  63. doi request reprint Treating osteoporosis in Canada: what clinical efficacy data should be considered by policy decision makers?
    J D Adachi
    Department of Medicine, St Joseph s, Healthcare McMaster University, 25 Charlton Avenue East, Suite 501, Hamilton, Ontario, L8N 1Y2, Canada
    Osteoporos Int 20:1785-93. 2009
    ..The choice of clinical efficacy data is an important consideration in health economic models evaluating osteoporosis therapies...
  64. doi request reprint The Ontario Osteoporosis Strategy: implementation of a population-based osteoporosis action plan in Canada
    S B Jaglal
    Department of Physical Therapy, University of Toronto, 160 500 University Ave, Toronto, ON, M5G 1V7, Canada
    Osteoporos Int 21:903-8. 2010
    ....
  65. ncbi request reprint Risk factors associated with incident clinical vertebral and nonvertebral fractures in postmenopausal women: the Canadian Multicentre Osteoporosis Study (CaMos)
    Alexandra Papaioannou
    Department of Medicine, St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 16:568-78. 2005
    ..Furthermore, various anthropometric measures, disease conditions, and medications are associated with a new fracture. Identifying postmenopausal women at risk is important given that fracture prevention therapies are now available...
  66. pmc Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study
    George Ioannidis
    Department of Medicine, McMaster University, Hamilton, Ont
    CMAJ 181:265-71. 2009
    ..Fractures have largely been assessed by their impact on quality of life or health care costs. We conducted this study to evaluate the relation between fractures and mortality...
  67. ncbi request reprint A 6-mo home-based exercise program may slow vertebral height loss
    Colin E Webber
    Hamilton Health Sciences, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5
    J Clin Densitom 6:391-400. 2003
    ..1 mm anteriorly, -0.3 mm at the mid-location, and +0.2 mm posteriorly. The benefit of exercise in preserving vertebral morphometry in patients with osteoporosis deserves further investigation...
  68. ncbi request reprint In whom and how to prevent glucocorticoid-induced osteoporosis
    Jonathan D Adachi
    St Joseph s Healthcare, McMaster University, Hamilton, Ont, Canada
    Best Pract Res Clin Rheumatol 19:1039-64. 2005
    ..Today we have therapies with proven efficacy for the prevention of vertebral fractures and bone loss. Consequently recognition of glucocorticoid-induced osteoporosis is extremely important given the availability of effective therapy...
  69. doi request reprint Exploring the determinants of fracture risk among individuals with spinal cord injury
    D Lala
    Department of Kinesiology, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada
    Osteoporos Int 25:177-85. 2014
    ..In this cross-sectional study, we found that areal bone mineral density (aBMD) at the knee and specific tibia bone geometry variables are associated with fragility fractures in men and women with chronic spinal cord injury (SCI)...
  70. doi request reprint Cortical and trabecular bone at the radius and tibia in postmenopausal breast cancer patients: a Peripheral Quantitative Computed Tomography (pQCT) study
    K A Szabo
    Department of Nuclear Medicine, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada
    Bone 48:218-24. 2011
    ..Furthermore, this novel study found adverse effects from Anastrozole treatment primarily in cortical bone...
  71. doi request reprint Risk factors for low bone mass in healthy 40-60 year old women: a systematic review of the literature
    E J Waugh
    Osteoporosis Research Program, Women s College Hospital, Toronto, ON, Canada
    Osteoporos Int 20:1-21. 2009
    ..The use of body weight to identify high risk women may reduce unnecessary BMD testing in this age group...
  72. ncbi request reprint Treating osteoporosis: economic aspects of bisphosphonate therapy
    Courtney C Kennedy
    Department of Medicine, McMaster University, Ontario, Canada
    Expert Opin Pharmacother 7:1457-67. 2006
    ..This paper reviews a number of these studies regarding the economic benefits of treating osteoporosis with bisphosphonates and considers for whom prevention and/or treatment is most warranted...
  73. pmc Management of osteoporosis in men: an update and case example
    Aliya A Khan
    Division of Endocrinology and Geriatrics, Department of Medicine, McMaster University, Hamilton, Ont
    CMAJ 176:345-8. 2007
    ..The current paper supplements that guideline and provides a review and synthesis of the current literature on the diagnosis and management of osteoporosis in men...
  74. pmc Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density
    Lisa Langsetmo
    Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, Canada
    BMC Musculoskelet Disord 11:20. 2010
    ....
  75. doi request reprint Too Fit To Fracture: exercise recommendations for individuals with osteoporosis or osteoporotic vertebral fracture
    L M Giangregorio
    Department of Kinesiology, University of Waterloo, 200 University Ave, Waterloo, ON, N2L 3G1, Canada
    Osteoporos Int 25:821-35. 2014
    ..A consensus process was conducted to develop exercise recommendations for individuals with osteoporosis or vertebral fractures. A multicomponent exercise program that includes balance and resistance training is recommended...
  76. doi request reprint Reproducibility of computer-assisted joint alignment measurement in OA knee radiographs
    A K O Wong
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Osteoarthritis Cartilage 17:579-85. 2009
    ....
  77. doi request reprint Trends in hip fracture rates in Canada
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    JAMA 302:883-9. 2009
    ..Hip fractures are a public health concern because they are associated with significant morbidity, excess mortality, and the majority of the costs directly attributable to osteoporosis...
  78. ncbi request reprint Long-term tolerability of the bisphosphonates in postmenopausal osteoporosis: a comparative review
    Raheem B Kherani
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Drug Saf 25:781-90. 2002
    ..Each of these bisphosphonates have been shown to have comparable safety with placebo up to 3 to 4 years, with the most rigourous trials carried out for alendronate and risedronate. Long-term comparative studies are awaited...
  79. ncbi request reprint Do hip protectors decrease the risk of hip fracture in institutional and community-dwelling elderly? A systematic review and meta-analysis of randomized controlled trials
    Anna M Sawka
    Division of Endocrinology and Department of Medicine, St Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    Osteoporos Int 16:1461-74. 2005
    ..Thus, there is little evidence to support the use of hip protectors outside the nursing home setting. The potential benefit of hip protectors in reducing hip fractures in nursing home residents requires further confirmation...
  80. ncbi request reprint What predicts early fracture or bone loss on bisphosphonate therapy?
    Anna M Sawka
    McMaster University, Hamilton, ON, CA
    J Clin Densitom 6:315-22. 2003
    ..13, 0.62, p = 0.002). In conclusion, early fracture on bisphosphonate therapy is most strongly predicted by a previous history of fracture and early bone loss is most strongly predicted by the potency of the prescribed bisphosphonate...
  81. ncbi request reprint Prevalence of osteoporosis in osteoarthritic patients undergoing total hip or total knee arthroplasty
    Anna Labuda
    Department of Physical Medicine and Rehabilitation, Henderson General Hospital, Hamilton, ON, Canada
    Arch Phys Med Rehabil 89:2373-4. 2008
    ..To determine the prevalence of osteoporosis in osteoarthritic patients undergoing total hip or total knee arthroplasty...
  82. ncbi request reprint A systematic review of the effect of alendronate on bone mineral density in men
    Anna M Sawka
    McMaster University, Hamilton, Ontario, Canada L8N 1Y2
    J Clin Densitom 8:7-13. 2005
    ..We conclude that 10 mg of oral daily alendronate is significantly associated with increase in BMD at the lumbar spine and hip in men over 2-3 yr and that these changes are similar to those previously observed in postmenopausal women...
  83. doi request reprint Family physicians' personal and practice characteristics that are associated with improved utilization of bone mineral density testing and osteoporosis medication prescribing
    George Ioannidis
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Popul Health Manag 12:131-8. 2009
    ..The education of both clinicians and policy makers regarding these new insights may translate to enhanced individual practices and an improved overall health care system to optimize the environment for managing osteoporosis...
  84. ncbi request reprint Are there differences between men and women prescribed bisphosphonate therapy in canadian subspecialty osteoporosis practices?
    Anna M Sawka
    McMaster University, St Joseph s Healthcare, Centre for Evaluation of Medicines, Hamilton, Ontario, Canada
    J Rheumatol 31:1993-5. 2004
    ..To determine if there are differences between men and women referred for treatment of osteoporosis in Canada...
  85. ncbi request reprint Effect of selective serotonin reuptake inhibitors on the risk of fracture
    J Brent Richards
    Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, Quebec, Canada
    Arch Intern Med 167:188-94. 2007
    ..Our objective was to examine the effect of daily SSRI use on the risk of incident clinical fragility fracture...
  86. ncbi request reprint Systemic lupus erythematosus presenting as subacute delirium in an 82-year-old woman
    G A Heckman
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Am Geriatr Soc 49:458-61. 2001
    ..CONCLUSION: Neuropsychiatric symptoms can be prominent in older people, presenting features of SLE. This case illustrates the lowest dose of corticosteroids shown to be effective in an older patient with delirium due to SLE...
  87. ncbi request reprint Measurement of cervical flexor endurance following whiplash
    Dinesh A Kumbhare
    Department of Medicine, McMaster University and Center for Acute Injury Rehabilitation, St Joseph s Hospital, Hamilton, Ontario, Canada
    Disabil Rehabil 27:801-7. 2005
    ....
  88. ncbi request reprint The effects of antifracture therapies on the components of bone strength: assessment of fracture risk today and in the future
    K Shawn Davison
    Clinical Research Scientist, Department of Medicine, Laval University, Sainte Foy, Quebec, Canada
    Semin Arthritis Rheum 36:10-21. 2006
    ..To summarize the current knowledge regarding the impact of the most common antifracture medications on the various determinants of bone strength...
  89. pmc Does alendronate reduce the risk of fracture in men? A meta-analysis incorporating prior knowledge of anti-fracture efficacy in women
    Anna M Sawka
    Department of Medicine, St, Joseph s Healthcare and McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 6:39. 2005
    ..Our objective was to systematically review the anti-fracture efficacy of alendronate in men with low bone mass or with a history of prevalent fracture(s) and incorporate prior knowledge of alendronate efficacy in women in the analysis...
  90. ncbi request reprint Hip protectors decrease hip fracture risk in elderly nursing home residents: a Bayesian meta-analysis
    Anna M Sawka
    Division of Endocrinology and Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 60:336-44. 2007
    ....
  91. ncbi request reprint Bone strength: the whole is greater than the sum of its parts
    K Shawn Davison
    Clinical Research Scientist, Department of Medicine, Laval University, Sainte Foy, Quebec, Canada
    Semin Arthritis Rheum 36:22-31. 2006
    ..To summarize the current knowledge regarding the various determinants of bone strength...
  92. ncbi request reprint Renal impairment and medication use among psychogeriatric inpatients
    Michel Bedard
    Lakehead Psychiatric Hospital, Thunder Bay, Ontario, Canada
    Can J Clin Pharmacol 10:78-82. 2003
    ..To determine the prevalence of renal impairment and the dosage appropriateness of several medications for which dosing guidelines in the advent of renal impairment are available...
  93. ncbi request reprint Attitudes of women who are currently using or recently stopped estrogen replacement therapy with or without progestins: results of the AWARE survey
    Anna M Sawka
    Department of Endocrinology and Metabolism, McMaster University, Hamilton ON
    J Obstet Gynaecol Can 26:967-73. 2004
    ..To examine the level of awareness of the findings of the Women's Health Initiative (WHI) study among recent users of hormone therapy (HT)...
  94. ncbi request reprint Estimating the prevalence of renal insufficiency in seniors requiring long-term care
    Amit X Garg
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 65:649-53. 2004
    ..The objective of this study was to estimate the prevalence of low glomerular filtration rate (GFR) in a large sample of elderly adults living in long-term care facilities, and to compare two commonly used methods for estimating GFR...
  95. pmc Parathyroid hormone for the treatment of osteoporosis: a systematic review
    Ann Cranney
    Department of Medicine, University of Ottawa, Ottawa, Ont
    CMAJ 175:52-9. 2006
    ....
  96. pmc Canadian Quality Circle pilot project in osteoporosis: rationale, methods, and feasibility
    George Ioannidis
    McMaster University in Hamilton, Ont
    Can Fam Physician 53:1694-700. 2007
    ..PROBLEM ADDRESSED Family physicians are not adequately following the 2002 Osteoporosis Canada guidelines for providing optimal care to patients with osteoporosis...
  97. pmc Patients' adherence to osteoporosis therapy: exploring the perceptions of postmenopausal women
    Elaine Lau
    Department of Pharmacy, Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Can Fam Physician 54:394-402. 2008
    ..To explore the experiences and perceptions of postmenopausal women regarding strategies to improve adherence to osteoporosis therapy...
  98. ncbi request reprint Vertebral compression fractures in primary care: recommendations from a consensus panel
    Stephen Brunton
    Cabarrus Family Medicine Residency Program, Charlotte, NC, USA
    J Fam Pract 54:781-8. 2005
  99. ncbi request reprint A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis
    Jean Jacques Body
    Department of Medicine, Institut J Bordet, Universite Libre de Bruxelles, 1000 Brussels, Belgium
    J Clin Endocrinol Metab 87:4528-35. 2002
    ..In conclusion, teriparatide, a bone formation agent, increased BMD at most sites and decreased nonvertebral fractures more than alendronate...
  100. pmc Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents
    Claudie Berger
    CaMos Methods Centre, McGill University, Montreal, Que
    CMAJ 178:1660-8. 2008
    ..We sought to estimate the average rate of change in bone mineral density as a function of age among Canadians aged 25-85, stratified by sex and use of antiresorptive agents...