Madhu K Natarajan

..A secondary objective was to identify predictors of cardiac events that occur while patients are waiting...

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..This study examined the relative effects of dalteparin and UFH on coagulation and angiographic and clinical indices during PCI...

..Previous studies have shown that many low-risk patients remain in hospital significantly longer...

..However, recent reports suggest there may be an increase in late stent thrombosis with long-term follow-up in PES-treated patients...

..The purpose of this study is to assess the feasibility of evaluating the added benefit and safety of triple therapy (TT-warfarin, ASA, and clopidogrel) versus dual therapy (DT-ASA and clopidogrel) in patients at risk of LVT post aSTEMI...

..The purpose of this trial was to evaluate the effectiveness of an evidence-based PtDA compared with usual care in patients eligible for radial and femoral artery access...

..The objective of this study was to determine whether insulin-mediated glucose lowering reduces in-stent restenosis in patients with diabetes undergoing PCIs...

..Therapies that maintain efficacy while reducing bleeding and that reduce the risk of death in patients who develop bleeding are needed...

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..PES implantation appears to be safe and possibly superior to BMS implantation in terms of 1-year major cardiovascular outcomes in the setting of ST-elevation myocardial infarction...

..The purpose of this study is to describe our experience over the past decade in attempting to meet RMWTs for patients needing CATH at our centre, and to discuss issues concerning capacity planning in providing timely service...

..It was previously reported that Canadian patients had reduced rates of 30-day and one-year death, myocardial infarction (MI) or target vessel revascularization (TVR) compared with patients in the United States (US)...

..Earlier trials have shown that a routine invasive strategy improves outcomes in patients with acute coronary syndromes without ST-segment elevation. However, the optimal timing of such intervention remains uncertain...

..Limited data exist for radial access in acute myocardial infarction, where reperfusion must occur quickly...

..However, the effectiveness of PES in patients treated during routine practice has not been fully established...

..We performed a randomized trial to determine the safety and feasibility of fondaparinux in the percutaneous coronary intervention (PCI) setting...

..The Zwolle primary percutaneous coronary intervention (PCI) index is an externally validated risk score that has been used to identify low-risk primary PCI patients who can safely be discharged from the hospital within 48 h to 72 h...

..Discontinuation of cardiac medications in such patients is associated with increased mortality...

..Patients receiving dialysis have a high burden of cardiovascular disease. Some receive coronary artery revascularization but the optimal method is controversial...

..Healthcare providers are challenged with both implementing strategies for improving care (minimizing delays to reperfusion) for patients not using EMS, and encouraging patients to access care via EMS in the event of acute chest pain...

..CONCLUSIONS: Obesity is not associated with increased risk of adverse postprocedural in-hospital outcomes. These findings, however, do not discount the need for sustained efforts in secondary prevention of obesity and its consequences...

..The authors sought to compare the radiation dose between radial and femoral access...

..The study assessed the appropriateness of coronary revascularization in Ontario, Canada, and examined its association with longer-term outcomes...

..Variations in the rate of use of common medical procedures/therapies are widely documented. Previous studies tend to focus on variations between either hospitals or geographic areas. Few studies examine within centre practice variations...

..Few data are available comparing PCI outcomes between the two countries in the era of coronary stenting and adjunctive glycoprotein IIb/IIIa inhibition...

..To identify the prevalence and predictors of VAS bruising in the 5-7 days following cardiac catheterisation or percutaneous coronary intervention...

..In revealing a priori known factors associated with an increased radiation dose during PCI, physicians and patients might be more able to evaluate the risks and benefits of such a procedure...

..Our objective was to evaluate the extent to which demand-side factors such as clinical urgency/need, and supply-side factors, as reflected by differences in physician and procedural supply account for these inequalities...

..CONCLUSIONS: Coronary stenting is associated with transient increases in both CRP and IL-6 levels. However, pre-procedural CRP and IL-6 levels do not predict late coronary angiographic restenosis...

..However, approximately one-third of patients still had an LDL level above recommended guidelines for secondary prevention...

..No direct comparisons exist of the renal tolerability of the low-osmolality contrast medium iopamidol with that of the iso-osmolality contrast medium iodixanol in high-risk patients...

..0% (95% CI, 12.5%-27.5%). The results of the Medstent study in discrete, de novo native coronary lesions demonstrated low incidence of clinical events as well as favorable angiographic restenosis rate...

..As a subsequent focus, this article presents the process for setting benchmarks for optimizing administered dose in the Hamilton Health Sciences Heart Investigation Unit...