P Moayyedi

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. pmc Randomized controlled trial comparing telephone and mail follow-up for recruitment of participants into a clinical trial of colorectal cancer screening
    Arthur D Wong
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Trials 14:40. 2013
  2. doi request reprint Dyspepsia
    Paul Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, Canada
    Curr Opin Gastroenterol 28:602-7. 2012
  3. doi request reprint The impact of intensifying acid suppression on sleep disturbance related to gastro-oesophageal reflux disease in primary care
    P Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 37:730-7. 2013
  4. doi request reprint The risks of PPI therapy
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University, 1280 Main Street West, HSC room 4W8E, Hamilton, ON L8S 4K1, Canada
    Nat Rev Gastroenterol Hepatol 9:132-9. 2012
  5. doi request reprint The gain in quality-adjusted life months by switching to esomeprazole in those with continued reflux symptoms in primary care: EncomPASS--a cluster-randomized trial
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Am J Gastroenterol 105:2341-6. 2010
  6. ncbi request reprint Can the clinical history distinguish between organic and functional dyspepsia?
    Paul Moayyedi
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    JAMA 295:1566-76. 2006
  7. ncbi request reprint Helicobacter pylori public health implications
    Paul Moayyedi
    Department of Medicine, Gastroenterology Division, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Helicobacter 9:67-72. 2004
  8. ncbi request reprint Association between Helicobacter pylori infection and adult height
    Paul Moayyedi
    AstraZeneca Richard Hunt Chair of Gastroenterology, Department of Medicine, McMaster University, 1200 Main St W, HSC 3N51D Hamilton, Ontario, Canada
    Eur J Epidemiol 20:455-65. 2005
  9. ncbi request reprint The efficacy of proton pump inhibitors in nonulcer dyspepsia: a systematic review and economic analysis
    Paul Moayyedi
    Gastroenterology Division, McMaster University, Hamilton, Ontario, Canada
    Gastroenterology 127:1329-37. 2004
  10. ncbi request reprint Review article: gastro-oesophageal reflux disease--the extent of the problem
    P Moayyedi
    Department of Medicine, Division of Gastroenterology, McMaster University Medical Centre, Hamilton, ON, Canada
    Aliment Pharmacol Ther 22:11-9. 2005

Collaborators

Detail Information

Publications90

  1. pmc Randomized controlled trial comparing telephone and mail follow-up for recruitment of participants into a clinical trial of colorectal cancer screening
    Arthur D Wong
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Trials 14:40. 2013
    ..Investigators often face challenges when recruiting participants into randomized controlled trials (RCTs). Some data suggest that telephone reminders may lead to greater participant enrollment...
  2. doi request reprint Dyspepsia
    Paul Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, Canada
    Curr Opin Gastroenterol 28:602-7. 2012
    ..pylori. Patients who remain symptomatic with this strategy may be investigated with endoscopy, but most will have functional dyspepsia...
  3. doi request reprint The impact of intensifying acid suppression on sleep disturbance related to gastro-oesophageal reflux disease in primary care
    P Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 37:730-7. 2013
    ..Sleep disturbance is common in patients with GERD but there has been little evaluation of this problem in primary care in patients already taking therapy...
  4. doi request reprint The risks of PPI therapy
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University, 1280 Main Street West, HSC room 4W8E, Hamilton, ON L8S 4K1, Canada
    Nat Rev Gastroenterol Hepatol 9:132-9. 2012
    ..As with any therapy, therefore, it is advisable to prescribe PPIs only to patients for whom these drugs have been proven beneficial...
  5. doi request reprint The gain in quality-adjusted life months by switching to esomeprazole in those with continued reflux symptoms in primary care: EncomPASS--a cluster-randomized trial
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Am J Gastroenterol 105:2341-6. 2010
    ..We expressed the data in terms of cost per quality-adjusted life months (QALM), as this was a 4-week trial...
  6. ncbi request reprint Can the clinical history distinguish between organic and functional dyspepsia?
    Paul Moayyedi
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    JAMA 295:1566-76. 2006
    ..Upper gastrointestinal symptoms occur in 40% of the population. An accurate diagnosis would help rationalize investigation and treatment...
  7. ncbi request reprint Helicobacter pylori public health implications
    Paul Moayyedi
    Department of Medicine, Gastroenterology Division, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Helicobacter 9:67-72. 2004
    ..The medical community should be consistent and if we are instituting other population screening programmes without randomized controlled trial evidence then H. pylori testing and treatment should also be considered...
  8. ncbi request reprint Association between Helicobacter pylori infection and adult height
    Paul Moayyedi
    AstraZeneca Richard Hunt Chair of Gastroenterology, Department of Medicine, McMaster University, 1200 Main St W, HSC 3N51D Hamilton, Ontario, Canada
    Eur J Epidemiol 20:455-65. 2005
    ..A cross-sectional survey was performed to evaluate the association between H. pylori and adult height...
  9. ncbi request reprint The efficacy of proton pump inhibitors in nonulcer dyspepsia: a systematic review and economic analysis
    Paul Moayyedi
    Gastroenterology Division, McMaster University, Hamilton, Ontario, Canada
    Gastroenterology 127:1329-37. 2004
    ..We conducted a systematic review to evaluate whether PPI therapy had any effect in nonulcer dyspepsia and constructed a health economic model to assess the cost-effectiveness of this approach...
  10. ncbi request reprint Review article: gastro-oesophageal reflux disease--the extent of the problem
    P Moayyedi
    Department of Medicine, Division of Gastroenterology, McMaster University Medical Centre, Hamilton, ON, Canada
    Aliment Pharmacol Ther 22:11-9. 2005
    ..Reflux symptoms were less common in East Asian populations with only 7% having heartburn at least once per month. Heartburn is a significant problem in Western societies...
  11. doi request reprint The efficacy of probiotics in the treatment of irritable bowel syndrome: a systematic review
    P Moayyedi
    Department of Medicine, Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, HSC 4W8E, Hamilton, ON L8N 3Z5, Canada
    Gut 59:325-32. 2010
    ..Probiotics may benefit irritable bowel syndrome (IBS) symptoms, but randomised controlled trials (RCTs) have been conflicting; therefore a systematic review was conducted...
  12. ncbi request reprint Should we test for Helicobacter pylori before treating gastroesophageal reflux disease?
    Paul Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 19:425-7. 2005
    ..23 to 0.32). H. pylori eradication is therefore recommended in children with GERD that are having an endoscopy. However, when the diagnosis of GERD is being made clinically or by pH monitoring, it is not necessary to screen for H. pylori...
  13. doi request reprint Economic reflections on proton pump inhibitor therapy for non-erosive reflux disease
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ont, Canada
    Digestion 78:61-9. 2008
    ..PPI therapy is also likely to be a cost-effective strategy for non-erosive reflux disease at generic but not at proprietary prices...
  14. ncbi request reprint Mortality rates in patients with Barrett's oesophagus
    P Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 27:316-20. 2008
    ..Patients with Barrett's oesophagus are at increased risk of oesophageal adenocarcinoma. Observational studies have suggested increase in overall mortality also but data are conflicting...
  15. ncbi request reprint Sequential regimens for Helicobacter pylori eradication
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, ON, Canada L8N 3Z5
    Lancet 370:1010-2. 2007
  16. doi request reprint Symptom-based diagnostic criteria for irritable bowel syndrome: the more things change, the more they stay the same
    Paul Moayyedi
    Division of Gastroenterology, Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University Medical Centre, 1200 Main Street West, HSC room 4W8E, Hamilton, ON, L8N 3Z5 Canada
    Gastroenterol Clin North Am 40:87-103. 2011
    ..However, the most common causes of symptoms of the gastrointestinal tract are functional. It is important that clinicians obtain a thorough history so that the disorder of the patient can be accurately defined...
  17. ncbi request reprint Colorectal cancer screening lacks evidence of benefit
    Paul Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Cleve Clin J Med 74:545, 549-50, 552 passim. 2007
    ..Whether this phenomenon is due to anxiety, test bias, or merely chance, more evidence is needed; widespread screening in the general population is premature...
  18. ncbi request reprint The health economics of Helicobacter pylori infection
    Paul Moayyedi
    Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, HSC room 4W8E, Hamilton, ON L8N 3Z5, Canada
    Best Pract Res Clin Gastroenterol 21:347-61. 2007
    ..RCTs have suggested this approach may be cost saving but more data are needed on whether H. pylori eradication will reduce gastric cancer mortality before this strategy can be recommended...
  19. doi request reprint The epidemiology of obesity and gastrointestinal and other diseases: an overview
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, Canada
    Dig Dis Sci 53:2293-9. 2008
    ..Although the exact cause remains uncertain, these symptoms may be connected to eating habits or to changes in gastrointestinal motility...
  20. doi request reprint Meta-analysis: Helicobacter pylori'test and treat' compared with empirical acid suppression for managing dyspepsia
    A C Ford
    Division of Gastroenterology, McMaster University, Health Sciences Centre, Hamilton, ON, Canada
    Aliment Pharmacol Ther 28:534-44. 2008
    ..Aim To conduct an individual patient data meta-analysis of randomized controlled trials (RCTs) of 'test and treat' vs. empirical acid suppression in adults with uncomplicated dyspepsia in primary care...
  21. doi request reprint Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis
    A C Ford
    Gastroenterology Division, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada
    Gut 58:367-78. 2009
    ..Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. Evidence for treatment of the condition with antidepressants and psychological therapies is conflicting...
  22. doi request reprint Prevalence of uninvestigated dyspepsia 8 years after a large waterborne outbreak of bacterial dysentery: a cohort study
    Alexander C Ford
    Department of Medicine, Division of Gastroenterology, and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Gastroenterology 138:1727-36; quiz e12. 2010
    ..We assessed prevalence of uninvestigated dyspepsia in a cohort of individuals, some of whom were exposed to bacterial dysentery in May 2000, as well as risk factors for dyspepsia in exposed individuals...
  23. ncbi request reprint Canadian Helicobacter Study Group Consensus Conference: Update on the approach to Helicobacter pylori infection in children and adolescents--an evidence-based evaluation
    Billy Bourke
    Division of GI Nutrition, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Ontario, Canada
    Can J Gastroenterol 19:399-408. 2005
    ..pylori infection in children is 14 days; and H. pylori culture and antibiotic sensitivity testing should be made available to monitor population antibiotic resistance and manage treatment failures...
  24. doi request reprint Diagnostic utility of alarm features for colorectal cancer: systematic review and meta-analysis
    A C Ford
    Gastroenterology Division, McMaster University, Health Sciences Centre, 1200 Main Street West, Hamilton, Ontario, Canada
    Gut 57:1545-53. 2008
    ..Alarm features are used to prioritize access to urgent investigation, but there is little information concerning their utility in the diagnosis of colorectal cancer...
  25. ncbi request reprint Cost-utility and cost-benefit analyses: how did we get here and where are we going?
    Paul Moayyedi
    Gastroenterology Division, McMaster University, Hamilton, Ontario, Canada and Centre for Health Services Research, University of Newcastle upon Tyne, UK
    Eur J Gastroenterol Hepatol 16:527-34. 2004
    ..The results of cost-benefit analysis may provide more transparent guidance for policy makers, doctors and patients...
  26. doi request reprint Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery
    John K Marshall
    Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, Canada
    Gut 59:605-11. 2010
    ....
  27. ncbi request reprint Should patients with GERD be screened once at least for Barrett's epithelium? Con: Patients with GERD should be screened once at least for Barrett's esophagus--medicine or magic?
    Paul Moayyedi
    Gastroenterology Division, Department of Medicine, McMaster University, Hamilton, Ontario
    Am J Gastroenterol 99:2293-5. 2004
  28. ncbi request reprint Canadian Consensus Conference on the management of gastroesophageal reflux disease in adults - update 2004
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton
    Can J Gastroenterol 19:15-35. 2005
    ..Since the last Canadian Consensus Conference in 1996, GERD management has evolved substantially...
  29. pmc Adverse events with bismuth salts for Helicobacter pylori eradication: systematic review and meta-analysis
    Alexander C Ford
    Gastroenterology Division, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    World J Gastroenterol 14:7361-70. 2008
    ..To assess the safety of bismuth used in Helicobacter pylori (H pylori) eradication therapy regimens...
  30. pmc New approaches to enhance the accuracy of the diagnosis of reflux disease
    P Moayyedi
    Gastroenterology Division, McMaster University, Ontario, Canada
    Gut 53:iv55-7. 2004
    ..There will be some bias in the type of patient referred for diagnosis and this usually decreases the specificity of symptom diagnosis...
  31. doi request reprint Canadian consensus guidelines on long-term nonsteroidal anti-inflammatory drug therapy and the need for gastroprotection: benefits versus risks
    A Rostom
    Division of Gastroenterology, University of Calgary Medical Clinic, AB, Canada
    Aliment Pharmacol Ther 29:481-96. 2009
    ..Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, but are not without risks...
  32. doi request reprint Meta-analysis: yield of diagnostic tests for coeliac disease in dyspepsia
    A C Ford
    Gastroenterology Division, McMaster University, Health Sciences Centre, Hamilton, ON, Canada
    Aliment Pharmacol Ther 30:28-36. 2009
    ..The prevalence of coeliac disease (CD) may be increased in individuals with dyspepsia, but evidence is conflicting...
  33. ncbi request reprint Does fecal occult blood testing really reduce mortality? A reanalysis of systematic review data
    Paul Moayyedi
    Gastroenterology Division, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 101:380-4. 2006
    ..Systematic reviews suggest that FOBT is effective in reducing CRC mortality but the data on overall mortality from any cause has rarely been synthesized...
  34. doi request reprint Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis
    Alexandra Chloe Villani
    Division of Gastroenterology, Department of Medicine, McGill University, Montreal, Quebec, Canada
    Gastroenterology 138:1502-13. 2010
    ..2% of these developed IBS. We used this cohort to study genetic susceptibility to post-infectious (PI)-IBS...
  35. doi request reprint Systematic review and meta-analysis of the prevalence of irritable bowel syndrome in individuals with dyspepsia
    Alexander C Ford
    Gastroenterology Division, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Clin Gastroenterol Hepatol 8:401-9. 2010
    ..Dyspepsia and irritable bowel syndrome (IBS) are common conditions that can coexist in patients. We performed a systematic review and meta-analysis to estimate prevalence of IBS in dyspepsia...
  36. ncbi request reprint Gastro-oesophageal reflux disease
    Paul Moayyedi
    Department of Medicine, Division of Gastroenterology, McMaster University Medical Centre, Hamilton, ON, Canada
    Lancet 367:2086-100. 2006
    ..The role of endoscopic therapy is uncertain. Anti-reflux surgery is probably as effective as PPI therapy although there is a low operative mortality and morbidity...
  37. doi request reprint Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: systematic review and meta-analysis
    Alexander C Ford
    Gastroenterology Division, McMaster University, Health Sciences Center, Hamilton, Ontario, Canada
    Am J Gastroenterol 104:1831-43; quiz 1844. 2009
    ..We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to estimate the efficacy of all available 5-HT agents in IBS...
  38. pmc Bringing science to the art of diagnosis
    P Moayyedi
    Gastroenterology Division, McMaster University HSC 4W8, Hamilton, Ontario, Canada L8N 3Z5
    Gut 53:627-8. 2004
  39. doi request reprint Hip fracture and proton pump inhibitor therapy: balancing the evidence for benefit and harm
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 103:2428-31. 2008
    ..The association between proton pump inhibitor therapy and hip fracture is a good illustration of this dilemma. We use this example to highlight an approach that can be taken to critically evaluate the evidence for harms of medication...
  40. doi request reprint Yield of diagnostic tests for celiac disease in individuals with symptoms suggestive of irritable bowel syndrome: systematic review and meta-analysis
    Alexander C Ford
    MB MRCP, Gastroenterology Division, McMaster University, Health Sciences Centre, 1200 Main St W, Hamilton, ON L8N 3Z5, Canada
    Arch Intern Med 169:651-8. 2009
    ..Studies suggest that the prevalence of celiac disease is increased in individuals with IBS; however, evidence is conflicting, and current guidelines do not always recommend screening for celiac disease in these individuals...
  41. ncbi request reprint Systematic review of the risk of enteric infection in patients taking acid suppression
    Jennifer Leonard
    Department of Medicine, Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 102:2047-56; quiz 2057. 2007
    ..There have been concerns raised about the possible association of PPIs with enteric infections...
  42. doi request reprint Will the history and physical examination help establish that irritable bowel syndrome is causing this patient's lower gastrointestinal tract symptoms?
    Alexander C Ford
    Gastroenterology Division, McMaster University Medical Centre, 1200 Main St W, Hamilton, ON L8N 3Z5, Canada
    JAMA 300:1793-805. 2008
    ..These individuals are frequently diagnosed with irritable bowel syndrome (IBS) based on their symptoms; however, some may require additional testing or referral to specialists before this diagnosis is made...
  43. ncbi request reprint Is it safe to use a proton pump inhibitor with clopidogrel?
    Clara K Chow
    Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton General Hospital, Hamilton, ON, Canada
    Pol Arch Med Wewn 119:564-8. 2009
    ..As both drugs have very short half-lives, taking them with a large time gap between drugs (e.g., morning and night) may theoretically decrease the chance of interaction...
  44. doi request reprint Small intestinal bacterial overgrowth in irritable bowel syndrome: systematic review and meta-analysis
    Alexander C Ford
    Gastroenterology Division, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Clin Gastroenterol Hepatol 7:1279-86. 2009
    ..Small intestinal bacterial overgrowth (SIBO) has been proposed as an etiologic factor in irritable bowel syndrome (IBS), but evidence is conflicting. We conducted a systematic review and meta-analysis of the prevalence of SIBO in IBS...
  45. ncbi request reprint Meta-analysis: Can we mix apples and oranges?
    Paul Moayyedi
    Department of Medicine, Gastroenterology Division, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 99:2297-301. 2004
  46. doi request reprint Errors in the conduct of systematic reviews of pharmacological interventions for irritable bowel syndrome
    Alexander C Ford
    Gastroenterology Division, Health Sciences Center, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 105:280-8. 2010
    ..Although flawed systematic reviews could compromise optimal decision making, their accuracy has received limited investigation. We assessed conduct of systematic reviews of pharmaceutical interventions for irritable bowel syndrome (IBS)...
  47. doi request reprint International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding
    Alan N Barkun
    Division of Gastroenterology, Montreal General Hospital Site, McGill University Health Centre, Montreal, Quebec, Canada
    Ann Intern Med 152:101-13. 2010
    ..A multidisciplinary group of 34 experts from 15 countries developed this update and expansion of the recommendations on the management of acute nonvariceal upper gastrointestinal bleeding (UGIB) from 2003...
  48. pmc Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis
    Alexander C Ford
    Gastroenterology Division, McMaster University, Health Sciences Centre, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    BMJ 337:a2313. 2008
    ..To determine the effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome...
  49. ncbi request reprint International comparisons of manpower in gastroenterology
    Paul Moayyedi
    Department of Medicine, Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Am J Gastroenterol 102:478-81. 2007
    ..The United States had the most variation in the number of gastroenterologists per 100,000 of the population among states...
  50. doi request reprint Current guidelines for dyspepsia management
    Alexander C Ford
    Department of Academic Medicine, St James s University Hospital, Leeds, UK
    Dig Dis 26:225-30. 2008
    ..This article compares and contrasts dyspepsia management guidelines from several geographical regions...
  51. doi request reprint Irritable bowel syndrome: a 10-yr natural history of symptoms and factors that influence consultation behavior
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, Great George Street, Leeds, United Kingdom
    Am J Gastroenterol 103:1229-39; quiz 1240. 2008
    ..The natural history of the condition has been studied extensively, but few studies have examined factors that predict its new onset or health care-seeking behavior...
  52. ncbi request reprint Esophageal adenocarcinoma arising from Barrett's metaplasia has regional variations in the west
    Janusz A Jankowski
    Gastroenterology 122:588-90. 2002
  53. doi request reprint Gastric Cancer Consensus conference recommends Helicobacter pylori screening and treatment in asymptomatic persons from high-risk populations to prevent gastric cancer
    Nicholas J Talley
    Department of Internal Medicine and Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida 32224, USA
    Am J Gastroenterol 103:510-4. 2008
    ..pylori in particularly high-risk population settings. The evidence for these recommendations is summarized in this report, and the global and U.S. implications are considered...
  54. doi request reprint Asia-Pacific consensus guidelines on gastric cancer prevention
    Kwong Ming Fock
    Changi General Hospital, Singapore
    J Gastroenterol Hepatol 23:351-65. 2008
    ..Gastric cancer is a major health burden in the Asia-Pacific region but consensus on prevention strategies has been lacking. We aimed to critically evaluate strategies for preventing gastric cancer...
  55. doi request reprint Management of Barrett's esophagus in the UK: overtreated and underbiopsied but improved by the introduction of a national randomized trial
    Debasish Das
    Digestive Disease Centre, Leicester Royal Infirmary, Leicester, UK
    Am J Gastroenterol 103:1079-89. 2008
    ....
  56. doi request reprint Barrett's esophagus and obesity: the missing part of the puzzle
    Paul Moayyedi
    Am J Gastroenterol 103:301-3. 2008
    ..In particular, more research is needed on visceral adipose tissue and risk of esophageal adenocarcinoma, and whether obesity is an important risk factor for the development of neoplasia in those with Barrett's esophagus...
  57. ncbi request reprint Helicobacter pylori eradication therapy for nonulcer dyspepsia
    Paul Moayyedi
    Ann Intern Med 136:555-6; author reply 555-6. 2002
  58. ncbi request reprint Helicobacter pylori eradication has the potential to prevent gastric cancer: a state-of-the-art critique
    Peter Malfertheiner
    Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany
    Am J Gastroenterol 100:2100-15. 2005
    ..pylori-associated diseases...
  59. ncbi request reprint Ethnicity, gender, and socioeconomic status as risk factors for esophagitis and Barrett's esophagus
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, Leeds, United Kingdom
    Am J Epidemiol 162:454-60. 2005
    ..35) and of higher socioeconomic status (adjusted OR=1.58, 95% CI: 1.16, 2.15 (top tertile vs. bottom tertile)). White Caucasian ethnicity, male gender, and higher socioeconomic status are independent risk factors for Barrett's esophagus...
  60. ncbi request reprint Helicobacter pylori "test and treat" or endoscopy for managing dyspepsia: an individual patient data meta-analysis
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, United Kingdom
    Gastroenterology 128:1838-44. 2005
    ....
  61. pmc Dyspepsia results may not apply in primary care
    Brendan C Delaney
    BMJ 327:811. 2003
  62. ncbi request reprint An update of the Cochrane systematic review of Helicobacter pylori eradication therapy in nonulcer dyspepsia: resolving the discrepancy between systematic reviews
    Paul Moayyedi
    Gastroenterology Unit, Health Services Research, The City Hospital NHS Trust, Dudley Road, Winston Green, Birmingham B18 7QH, U K
    Am J Gastroenterol 98:2621-6. 2003
    ..pylori eradication therapy on nonulcer dyspepsia symptoms. We updated the Cochrane review and explored reasons for these discrepant results...
  63. ncbi request reprint Symptom-based outcome measures for dyspepsia and GERD trials: a systematic review
    Adam Fraser
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, The University of Birmingham, Edgbaston, Birmingham, UK
    Am J Gastroenterol 100:442-52. 2005
    ..Although a number of measures have been developed, it remains unclear which of these should be used in new trials...
  64. ncbi request reprint Re: Cost-effectiveness of aspirin chemoprevention for Barrett's esophagus
    Janusz Jankowski
    J Natl Cancer Inst 96:885-7; author reply 887. 2004
  65. ncbi request reprint Cost-effectiveness and long-term impact of Helicobacter pylori 'test and treat' service in reducing open access endoscopy referrals
    Aravamuthan Sreedharan
    Department of Gastroenterology, Centre for Digestive Diseases, The General Infirmary at Leeds, UK
    Eur J Gastroenterol Hepatol 16:981-6. 2004
    ..This has been substantiated by several randomized controlled trials comparing a 'test and treat' strategy with early endoscopy in these patients. However, the long-term impact of such a strategy is not established...
  66. ncbi request reprint Eradication therapy in Helicobacter pylori positive peptic ulcer disease: systematic review and economic analysis
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, Great George Street, Leeds, UK
    Am J Gastroenterol 99:1833-55. 2004
    ..We conducted a systematic review and economic analysis to ascertain the efficacy of eradication therapy in the treatment of H. pylori positive peptic ulcer disease...
  67. ncbi request reprint A community screening program for Helicobacter pylori saves money: 10-year follow-up of a randomized controlled trial
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, Leeds, United Kingdom
    Gastroenterology 129:1910-7. 2005
    ..We aimed to determine the effect of screening for H pylori on dyspepsia and dyspepsia-related resource use over 10 years...
  68. ncbi request reprint How can the current strategies for Helicobacter pylori eradication therapy be improved?
    Alex Ford
    Gastroenterology Unit, City Hospital National Health Service Trust, Dudley Road, Winston Green, Birmingham B18 7QH, United Kingdom
    Can J Gastroenterol 17:36B-40B. 2003
    ..The use of Helicobacter pylori eradication therapy is advocated in an increasing variety of situations. It is therefore important to optimise current strategies to eradicate H pylori infection...
  69. ncbi request reprint Colorectal cancer screening with fecal occult blood testing (FOBT): an international perspective
    Edgar Achkar
    Am J Gastroenterol 101:212. 2006
  70. ncbi request reprint A second-order simulation model of the cost-effectiveness of managing dyspepsia in the United States
    Pelham M Barton
    Health Economics Facility, University of Birmingham, UK
    Med Decis Making 28:44-55. 2008
    ..The objective of this study was to explore uncertainty in controversial areas of the 2005 American Gastroenterology Association position statement on the management of dyspepsia...
  71. ncbi request reprint Effect of sibling number in the household and birth order on prevalence of Helicobacter pylori: a cross-sectional study
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, Great George Street, Leeds, UK
    Int J Epidemiol 36:1327-33. 2007
    ..pylori) is acquired mainly in childhood, with studies demonstrating this is related to living conditions. Effects of sibling number and birth order on prevalence of infection have not been extensively studied...
  72. ncbi request reprint Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection
    Paul Moayyedi
    Centre for Digestive Diseases, The General Infirmary at Leeds, UK
    Int J Epidemiol 31:624-31. 2002
    ..The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain...
  73. pmc Helicobacter pylori test and treat versus proton pump inhibitor in initial management of dyspepsia in primary care: multicentre randomised controlled trial (MRC-CUBE trial)
    Brendan C Delaney
    Primary Care Clinical Sciences, University of Birmingham, Birmingham B15 2TT
    BMJ 336:651-4. 2008
    ..To determine the cost effectiveness of Helicobacter pylori "test and treat" compared with empirical acid suppression in the initial management of patients with dyspepsia in primary care...
  74. ncbi request reprint Helicobacter pylori and nonmalignant disease
    Paul Moayyedi
    City Hospital NHS Trust, Winson Green, Birmingham, UK
    Helicobacter 7:30-6. 2002
    ..Finally important new data are presented regarding the management of dyspepsia at the primary care level with the confirmation that the H. pylori 'test and treat' strategy in the appropriate setting is more cost-effective than endoscopy...
  75. pmc Recent developments in gastroenterology
    Paul Moayyedi
    Gastroenterology Unit, City Hospital NHS Trust, Birmingham B18 7QH
    BMJ 325:1399-402. 2002
  76. ncbi request reprint Helicobacter pylori infection
    Brendan C Delaney
    University of Birmingham, Birmingham, United Kingdom
    Am Fam Physician 67:2359-60. 2003
  77. pmc Initial poor quality of life and new onset of dyspepsia: results from a longitudinal 10-year follow-up study
    Alexander C Ford
    Department of Academic Medicine, Clinical Sciences Building, St James s University Hospital, Leeds, UK
    Gut 56:321-7. 2007
    ..However, few have reported the effect of quality of life on the development of dyspepsia. A 10-year longitudinal follow-up study examining the effect of quality of life on subsequent dyspepsia was performed...
  78. pmc Eradicating H pylori
    Brendan Delaney
    BMJ 328:1388-9. 2004
  79. ncbi request reprint Establishing patient preferences for gastroenterology clinic reorganization using conjoint analysis
    Paul Moayyedi
    Gastroenterology Health Services Research, City Hospital NHS Trust, Dudley Road, Winson Green, Birmingham B18 7QH, UK
    Eur J Gastroenterol Hepatol 14:429-33. 2002
    ..Decisions such as these are often made with little assessment of patient preferences. We have elicited patient preferences for the optimal use of time in the outpatient clinic...
  80. ncbi request reprint A systematic review of psychological therapies for nonulcer dyspepsia
    Shelly Soo
    South Tyneside District Hospital, South Shields, Tyne and Wear, U K
    Am J Gastroenterol 99:1817-22. 2004
    ....
  81. pmc The promises and perils of nurse-led flexible sigmoidoscopy screening
    Paul Moayyedi
    Can J Gastroenterol 21:280-2. 2007
  82. ncbi request reprint Detection of intestinal metaplasia in Barrett's esophagus: an observational comparator study suggests the need for a minimum of eight biopsies
    Rebecca Harrison
    Digestive Diseases Center, University Hospitals of Leicester, Leicester UK
    Am J Gastroenterol 102:1154-61. 2007
    ..We aimed to assess the frequency of intestinal metaplasia in 125 consecutive patients with columnar-lined esophagus and to determine the optimal biopsy protocol to detect intestinal metaplasia...
  83. ncbi request reprint Who consults with dyspepsia? Results from a longitudinal 10-yr follow-up study
    Alexander C Ford
    Centre for Digestive Diseases, Leeds General Infirmary, Leeds, United Kingdom
    Am J Gastroenterol 102:957-65. 2007
    ..Dyspepsia is common, and the condition is often chronic, with a relapsing and remitting nature. Factors influencing the decision to consult a physician with symptoms remain unclear...
  84. pmc Endoscopic screening and surveillance for Barrett's esophagus--clinical implications
    Hugh Barr
    Cranfield Postgraduate Medical School, Gloucestershire, Gloucestershire Royal Hospital, Gloucester, United Kingdom
    MedGenMed 8:88. 2006
    ..The detection of dysplasia requires increased surveillance and usually intervention either endoscopically or with surgery...
  85. ncbi request reprint Endoscopic screening and surveillance for Barrett's esophagus--clinical implications
    Hugh Barr
    Cranfield Postgraduate Medical School in Gloucestershire, Gloucestershire Royal Hospital, Gloucester, United Kingdom
    MedGenMed 8:66. 2006
    ..The detection of dysplasia requires increased surveillance and usually intervention either endoscopically or with surgery...
  86. ncbi request reprint NSAID and oesophageal adenocarcinoma: randomised trials needed to correct for bias
    Janusz Jankowski
    Lancet Oncol 7:7-8; author reply 8-9. 2006
  87. ncbi request reprint Diagnostic and therapeutic use of proton pump inhibitors in non-cardiac chest pain: a metaanalysis
    Filippo Cremonini
    Clinical Enteric Neuroscience, Translational and Epidemiological Research Program C E N T E R and Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 100:1226-32. 2005
    ....
  88. ncbi request reprint Gambling with gastroesophageal reflux disease: should we worry about the QALY?
    Paul Moayyedi
    Am J Gastroenterol 100:534-6. 2005
    ..Comparing health care in terms of cost per quality adjusted life year (QALY) gained is one approach to this problem although there are concerns about whose values should be elicited and how QALYs are measured...
  89. ncbi request reprint Measuring gastroesophageal reflux symptoms: musings from Marrakech
    Paul Moayyedi
    Am J Gastroenterol 100:19-20. 2005
    ..This has important implications for the development of future questionnaires in gastroesophageal reflux and other gastrointestinal diseases...
  90. ncbi request reprint American gastroenterological association technical review on the evaluation of dyspepsia
    Nicholas J Talley
    Division of Gastroenterology and Hepatology and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
    Gastroenterology 129:1756-80. 2005