Edward Mills

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi Smoking cessation reduces postoperative complications: a systematic review and meta-analysis
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Am J Med 124:144-154.e8. 2011
  2. ncbi An analysis of general medical and specialist journals that endorse CONSORT found that reporting was not enforced consistently
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, HSC 2C12, Faculty of Health Sciences, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    J Clin Epidemiol 58:662-7. 2005
  3. ncbi Natural health product-drug interactions: a systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ther Drug Monit 27:549-57. 2005
  4. ncbi Barriers to participation in HIV drug trials: a systematic review
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Lancet Infect Dis 6:32-8. 2006
  5. ncbi Natural health product-HIV drug interactions: a systematic review
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON L8N 3Z5, Canada
    Int J STD AIDS 16:181-6. 2005
  6. ncbi Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
    Edward Mills
    Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Eur J Clin Pharmacol 61:1-7. 2005
  7. ncbi African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia. An overview of evidence and pharmacology
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West Hamilton, L8N 3Z5, Canada
    Nutr J 4:19. 2005
  8. ncbi Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis
    Edward Mills
    Department of Clinical Epidemiology, McMaster University, Hamilton, ON, Canada
    J Pineal Res 39:360-6. 2005
  9. ncbi Determining the reporting quality of RCTs in clinical pharmacology
    Edward Mills
    University of Oxford, Oxford, UK
    Br J Clin Pharmacol 58:61-5. 2004
  10. ncbi Tenofovir trials raise ethical issues
    Edward Mills
    Centre for International Human Rights Law, University of Oxford, Canada
    HIV AIDS Policy Law Rev 10:31-2. 2005

Collaborators

Detail Information

Publications58

  1. ncbi Smoking cessation reduces postoperative complications: a systematic review and meta-analysis
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Am J Med 124:144-154.e8. 2011
    ..We aimed to review randomized trials and observational evidence to establish the effect of preoperative smoking cessation on postoperative complications and to determine if there is an optimal cessation period before surgery...
  2. ncbi An analysis of general medical and specialist journals that endorse CONSORT found that reporting was not enforced consistently
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, HSC 2C12, Faculty of Health Sciences, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    J Clin Epidemiol 58:662-7. 2005
    ..We aimed to determine if specialist journals implement specific Consolidated Standards for Reporting Trials (CONSORT) recommendations to the same extent as general medical journals...
  3. ncbi Natural health product-drug interactions: a systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ther Drug Monit 27:549-57. 2005
    ..With the exception of St. John wort, clinicians and the public do not have information that permits strong inferences about interactions between NHPs and conventional medications...
  4. ncbi Barriers to participation in HIV drug trials: a systematic review
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Lancet Infect Dis 6:32-8. 2006
    ..The findings of this study should aid drug trialists in developing strategies to maximise participation and cooperation in HIV clinical drug trials while adequately informing and protecting prospective participants...
  5. ncbi Natural health product-HIV drug interactions: a systematic review
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON L8N 3Z5, Canada
    Int J STD AIDS 16:181-6. 2005
    ..Considering patient values and the implications of these studies, further research is urgently required to determine the extent of interactions with other commonly used NHPs...
  6. ncbi Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
    Edward Mills
    Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Eur J Clin Pharmacol 61:1-7. 2005
    ..To determine whether ingestion of milk thistle affects the pharmacokinetics of indinavir...
  7. ncbi African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia. An overview of evidence and pharmacology
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West Hamilton, L8N 3Z5, Canada
    Nutr J 4:19. 2005
    ..Efforts should also be directed at evaluating the possible benefits of natural products in HIV/AIDS treatment...
  8. ncbi Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis
    Edward Mills
    Department of Clinical Epidemiology, McMaster University, Hamilton, ON, Canada
    J Pineal Res 39:360-6. 2005
    ..Confirming the efficacy and safety of melatonin in cancer treatment will require completion of blinded, independently conducted RCTs...
  9. ncbi Determining the reporting quality of RCTs in clinical pharmacology
    Edward Mills
    University of Oxford, Oxford, UK
    Br J Clin Pharmacol 58:61-5. 2004
    ..The Consolidated Standards for Reporting Trials (CONSORT) are recommendations for improving the quality of reports of randomized controlled trials (RCTs)...
  10. ncbi Tenofovir trials raise ethical issues
    Edward Mills
    Centre for International Human Rights Law, University of Oxford, Canada
    HIV AIDS Policy Law Rev 10:31-2. 2005
    ....
  11. ncbi Complementary therapies for the treatment of HIV: in search of the evidence
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Int J STD AIDS 16:395-403. 2005
    ..Vis à vis CAM's popularity, the paucity of clinical trials and their low methodological quality are concerning...
  12. ncbi Efficacy and safety of prostaglandin analogues in patients with predominantly primary open-angle glaucoma or ocular hypertension: a meta-analysis
    Oghenowede Eyawo
    Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada
    Clin Ophthalmol 3:447-56. 2009
    ..First-line therapy for primary open-angle glaucoma and ocular hypertension generally involves prostaglandin analogue therapy. The relative efficacy of differing prostaglandin therapy is disputed...
  13. ncbi Randomized trials stopped early for benefit: a systematic review
    Victor M Montori
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 294:2203-9. 2005
    ..These findings suggest clinicians should view the results of such trials with skepticism...
  14. ncbi Enrolling women into HIV preventive vaccine trials: an ethical imperative but a logistical challenge
    Edward Mills
    Centre for International Health and Human Rights Studies, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS Med 3:e94. 2006
  15. ncbi Prevalence of mental disorders among children exposed to war: a systematic review of 7,920 children
    Vindya Attanayake
    Faculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada
    Med Confl Surviv 25:4-19. 2009
    ..Given the number of current conflicts, there is a paucity of information regarding mental disorders among children affected by war...
  16. ncbi A randomized trial of Pegaptanib sodium for age-related macular degeneration used an innovative design to explore disease-modifying effects
    Edward Mills
    Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Clin Epidemiol 60:456-60. 2007
    ..We aimed to determine if this design would permit inferences regarding disease modification in a trial evaluating Pegaptanib sodium, an intra-ocular injection, for the treatment of age-related macular degeneration...
  17. ncbi Sexual slavery without borders: trafficking for commercial sexual exploitation in India
    Christine Joffres
    Simon Fraser University, Faculty of Health Sciences, Blusson Hall, Room 11300, 8888 University Drive, Burnaby, B, C, V5A 1S6, Canada
    Int J Equity Health 7:22. 2008
    ..This paper presents an overview of the trafficking of women and girls for sexual exploitation (CSE) in India; identifies the health impacts of CSE; and suggest strategies to respond to trafficking and related issues...
  18. ncbi Prevalence of mental disorders and torture among Bhutanese refugees in Nepal: a systemic review and its policy implications
    Edward Mills
    Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada
    Med Confl Surviv 24:5-15. 2008
    ..The international community must resolve this protracted crisis...
  19. ncbi Attitudes towards fibromyalgia: a survey of Canadian chiropractic, naturopathic, physical therapy and occupational therapy students
    Jason W Busse
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Complement Altern Med 8:24. 2008
    ....
  20. ncbi Interaction of St John's wort with conventional drugs: systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 329:27-30. 2004
    ..To determine the methodological quality of clinical trials that examined possible interactions of St John's wort with conventional drugs, and to examine the results of these trials...
  21. ncbi Impact of African herbal medicines on antiretroviral metabolism
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    AIDS 19:95-7. 2005
    ..Initiating policies to provide herbal medicines with antiretroviral agents may put patients at risk of treatment failure, viral resistance or drug toxicity...
  22. ncbi Safety and efficacy of echinacea (Echinacea angustafolia, e. purpurea and e. pallida) during pregnancy and lactation
    Daniel Perri
    Department of Clinical Pharmacology and Toxicology, University of Toronto, Canada
    Can J Clin Pharmacol 13:e262-7. 2006
    ..CONCLUSIONS: Echinacea is non-teratogenic when used during pregnancy. Caution with using Echinacea during lactation until further high quality human studies can determine its safety...
  23. ncbi Safety and efficacy of St. John's wort (hypericum) during pregnancy and lactation
    Jean Jacques Dugoua
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 13:e268-76. 2006
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  24. ncbi Safety and efficacy of ginkgo (Ginkgo biloba) during pregnancy and lactation
    Jean Jacques Dugoua
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 13:e277-84. 2006
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  25. ncbi Mitigation of antiretroviral-induced hyperlipidemia by hepatitis C virus co-infection
    Curtis L Cooper
    Division of Infectious Diseases, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    AIDS 21:71-6. 2007
    ..Hyperlipidemia is a recognized complication of HIV antiretroviral therapy. The interactions between HIV, hepatitis C virus (HCV), antiretroviral agents and lipids are not well understood...
  26. ncbi Conflict induced internal displacement in Nepal
    Sonal Singh
    MPH Program, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA
    Med Confl Surviv 23:103-10. 2007
    ....
  27. ncbi Safety and efficacy of blue cohosh (Caulophyllum thalictroides) during pregnancy and lactation
    Jean Jacques Dugoua
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University ofToronto, Toronto, Canada
    Can J Clin Pharmacol 15:e66-73. 2008
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  28. ncbi Safety and efficacy of chastetree (Vitex agnus-castus) during pregnancy and lactation
    Jean Jacques Dugoua
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University ofToronto, Toronto, Canada
    Can J Clin Pharmacol 15:e74-9. 2008
    ..This is one article in a series that systematically reviews the evidence for herbs commonly used during pregnancy and lactation...
  29. ncbi Safety and efficacy of cranberry (vaccinium macrocarpon) during pregnancy and lactation
    Jean Jacques Dugoua
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Facility of Pharmacy, University ofToronto, Canada
    Can J Clin Pharmacol 15:e80-6. 2008
    ..This is one article in a series that systematically reviews the evidence for herbs commonly used during pregnancy and lactation...
  30. ncbi Safety and efficacy of panax ginseng during pregnancy and lactation
    Dugald Seely
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 15:e87-94. 2008
    ..This is one article in a series that systematically reviews the evidence for herbs commonly used during pregnancy and lactation...
  31. ncbi Health food store recommendations: implications for breast cancer patients
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    Breast Cancer Res 5:R170-4. 2003
    ..Many breast cancer patients use complementary and alternative medicine (CAM). We aimed to determine what advice health food store employees present to individuals seeking treatment options for breast cancer...
  32. ncbi Safety and efficacy of black cohosh (Cimicifuga racemosa) during pregnancy and lactation
    Jean Jacques Dugoua
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 13:e257-61. 2006
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  33. ncbi The HIV/AIDS epidemic in Cambodia
    Edward Mills
    Lancet Infect Dis 5:596-7. 2005
  34. ncbi n-of-1 randomized controlled trials: an opportunity for complementary and alternative medicine evaluation
    Bradley C Johnston
    Complementary and Alternative Research and Education CARE Program, Department of Pediatrics, University of Alberta, Mackenzie Health Sciences Centre, Edmonton, Alberta T6G 2R7, Canada
    J Altern Complement Med 10:979-84. 2004
    ....
  35. ncbi Knowledge of safety and herb-drug interations amongst HIV+ individuals: a focus group study
    Blair Leonard
    Department of Medicine, University of Toronto
    Can J Clin Pharmacol 11:e227-31. 2004
    ..As the use of CAM grows, further research on how to disseminate reliable information on safety and efficacy to this potentially vulnerable population is required...
  36. ncbi Randomized trials stopped early for harm in HIV/AIDS: a systematic survey
    Edward Mills
    Centre for International Health and Human Rights Studies, North York, Ontario, Canada
    HIV Clin Trials 7:24-33. 2006
    ..We assessed the prevalence of randomized clinical trials (RCTs) stopped early for harm in HIV/AIDS and determined the quality of reporting of methods to inform the decision to stop the trial...
  37. ncbi HIV in Nepal: is the violent conflict fuelling the epidemic?
    Sonal Singh
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    PLoS Med 2:e216. 2005
  38. ncbi Adherence to antiretroviral therapy among a conflict-affected population in Northeastern Uganda: a qualitative study
    Peter Olupot-Olupot
    Mbale Regional Referral Hospital, Mbale, Uganda
    AIDS 22:1882-4. 2008
    ..Possible facilitating strategies included mobile teams, increased security and regularity of drug stocks...
  39. ncbi Herb-drug interaction implications in pediatric practice: an overview of pharmacokinetic trials
    Bradley C Johnston
    Arch Pediatr Adolesc Med 159:692. 2005
  40. ncbi Traditional African medicine in the treatment of HIV
    Edward Mills
    Lancet Infect Dis 5:465-7. 2005
  41. ncbi In vitro analysis of the herbal compound Essiac
    Dugald Seely
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, ON, Canada
    Anticancer Res 27:3875-82. 2007
    ..We aimed to address this deficiency by conducting a series of assays to determine some of the purported activities of Essiac in vitro...
  42. ncbi Addressing the emergence of pediatric vaccination concerns: recommendations from a Canadian policy analysis
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, ON
    Can J Public Health 97:139-41. 2006
    ..However, such an investment is easy to justify given the benefits offered by pediatric vaccination and the ramifications of failing to maintain confidence in vaccination programs or missing a vaccine-related adverse event...
  43. ncbi Closing comment: Evidence-based complementary and alternative medicine: is it a viable concept?
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Altern Complement Med 8:875-6. 2002
  44. ncbi Sale of kava extract in some health food stores
    Edward Mills
    CMAJ 169:1158-9. 2003
    ..Two months after the ban, 17 (57%) of 30 stores continued to sell kava. These findings demonstrate that health food stores may need to be better informed about the sale of restricted natural health products...
  45. ncbi Emerging issues associated with HIV patients seeking advice from health food stores
    Edward Mills
    Dept of Research, Canadian College of Naturopathic Medicine, North York, ON
    Can J Public Health 94:363-6. 2003
    ..To ascertain the recommendations, training and education of health food store employees and determine how they communicate the costs, benefits and risks associated with natural health products for the HIV/AIDS community...
  46. ncbi Pediatric HIV therapy in armed conflict
    Andrew Kiboneka
    AIDS 22:1097-8. 2008
  47. ncbi The state of child health and human rights in Nepal
    Sonal Singh
    Public Health Program, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    PLoS Med 3:e203. 2006
  48. ncbi Teaching Evidence-Based Complementary and Alternative Medicine (EBCAM); changing behaviours in the face of reticence: a cross-over trial
    Edward Mills
    Department of Research, The Canadian College of Naturopathic Medicine, North York, Canada
    BMC Med Educ 2:2. 2002
    ..In this study we attempt to determine if a workshop for final year students at a naturopathic college improved their ability to utilize critical appraisal concepts...
  49. ncbi An in vivo analysis of the herbal compound essiac
    Blair J N Leonard
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Anticancer Res 26:3057-63. 2006
    ..CONCLUSION: Essiac, administered in established in vivo experimental models, did not significantly demonstrate its purported physiological modifying effects...
  50. ncbi Diagnostic accuracy among the allied health professions: commentary on Grace et Al
    Dugald Seely
    Department of Clinical Epidemiology, The Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    J Altern Complement Med 12:701-2. 2006
  51. ncbi Cautious optimism for new HIV/AIDS prevention strategies
    Edward Mills
    Lancet 368:1236. 2006
  52. ncbi HIV testing and individual rights
    Edward Mills
    Science 314:417-9; author reply 417-9. 2006
  53. ncbi Free doctors and medical students detained in Nepal
    Sonal Singh
    Lancet 367:1730. 2006
  54. ncbi Barriers to participating in an HIV vaccine trial: a systematic review
    Edward Mills
    AIDS 18:2235-42. 2004
  55. ncbi Characteristics of pediatric and adolescent patients attending a naturopathic college clinic in Canada
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Pediatrics 115:e338-43. 2005
    ..We also determined factors associated with the use of CAM products and vaccination status...
  56. ncbi Impact of federal safety advisories on health food store advice
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, 1255 Sheppard Avenue East, North York, Ontario M2K 1E2, Canada
    J Gen Intern Med 19:269-72. 2004
    ..Twenty-two of 34 stores recommended kava kava, 9 of which mentioned safety concerns. Physicians should be aware that federal advisories may not affect sales of unsafe products...
  57. ncbi From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark
    Jean Jacques Dugoua
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada
    Can J Physiol Pharmacol 85:837-47. 2007
    ..pylori infection. Common cinnamon showed weak to very weak evidence of efficacy in treating oral candidiasis in HIV patients and chronic salmonellosis...
  58. ncbi More on India's HIV-1 epidemic
    Edward Mills
    CMAJ 173:17-8; author reply 18. 2005