J B Mahony
Affiliation: McMaster University
Shahid A, Chong S, Mahony J, Deen M, Selvaganapathy P. Electrical Tweezer for Droplet Transportation, Extraction, Merging and DNA Analysis. Micromachines (Basel). 2017;8: pubmed publisher
..This electromechanical tweezer is of interest in low-throughput, small-volume biological and chemical assays where the investigator requires direct and open access to the samples. ..
Mahony J. Nucleic acid amplification-based diagnosis of respiratory virus infections. Expert Rev Anti Infect Ther. 2010;8:1273-92 pubmed publisher
..These resistance assays together with new viral load tests will enable clinical laboratories to provide physicians with important information for optimal treatment of patients. ..
Mahony J, Chong S, Merante F, Yaghoubian S, Sinha T, Lisle C, et al
. Development of a respiratory virus panel test for detection of twenty human respiratory viruses by use of multiplex PCR and a fluid microbead-based assay. J Clin Microbiol. 2007;45:2965-70 pubmed
Mahony J, Chong S, Bulir D, Ruyter A, Mwawasi K, Waltho D. Multiplex loop-mediated isothermal amplification (M-LAMP) assay for the detection of influenza A/H1, A/H3 and influenza B can provide a specimen-to-result diagnosis in 40 min with single genome copy sensitivity. J Clin Virol. 2013;58:127-31 pubmed publisher
..M-LAMP had excellent sensitivity and specificity for detecting influenza A and B in NP specimens and when used together with a rapid specimen processing method provided a specimen-to-result diagnosis in 30 min. ..
Mahony J. Detection of respiratory viruses by molecular methods. Clin Microbiol Rev. 2008;21:716-47 pubmed publisher
Mahony J, Petrich A, Smieja M. Molecular diagnosis of respiratory virus infections. Crit Rev Clin Lab Sci. 2011;48:217-49 pubmed publisher
..These resistance assays, together with viral load assays, will enable clinical laboratories to provide physicians with new and important information for optimal treatment of respiratory virus infections. ..
Mahony J, Song X, Chong S, Faught M, Salonga T, Kapala J. Evaluation of the NucliSens Basic Kit for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in genital tract specimens using nucleic acid sequence-based amplification of 16S rRNA. J Clin Microbiol. 2001;39:1429-35 pubmed
..gonorrhoeae and C. trachomatis, using a multiplex NASBA assay using primers for both bacteria. The NucliSens Basic Kit offers a versatile platform for the development of sensitive RNA detection assays for sexually transmitted diseases. ..
Mahony J, Chong S, Bulir D, Ruyter A, Mwawasi K, Waltho D. Development of a sensitive loop-mediated isothermal amplification assay that provides specimen-to-result diagnosis of respiratory syncytial virus infection in 30 minutes. J Clin Microbiol. 2013;51:2696-701 pubmed publisher
..In summary, the M-LAMP assay had excellent sensitivity and specificity for detecting RSV A and B in NP specimens and, when coupled with a rapid specimen preparation method, could provide a specimen-to-result diagnosis time of 30 min. ..
Bulir D, Waltho D, Stone C, Liang S, Chiang C, Mwawasi K, et al
. Chlamydia Outer Protein (Cop) B from Chlamydia pneumoniae possesses characteristic features of a type III secretion (T3S) translocator protein. BMC Microbiol. 2015;15:163 pubmed publisher
..Together, these results support that CopB plays the role of a hydrophobic translocator. ..