Mark N Levine
Affiliation: McMaster University
- Levine M, Julian J, Bedard P, Eisen A, Trudeau M, Higgins B, et al. Prospective Evaluation of the 21-Gene Recurrence Score Assay for Breast Cancer Decision-Making in Ontario. J Clin Oncol. 2016;34:1065-71 pubmed publisher..001). The RS substantially influenced both oncologists' recommendations and patients' preferences for chemotherapy. The major effect was avoidance of chemotherapy when AOL indicated high or intermediate risk. ..
- Serrano P, Gafni A, Gu C, Gulenchyn K, Julian J, Law C, et al. Positron Emission Tomography-Computed Tomography (PET-CT) Versus No PET-CT in the Management of Potentially Resectable Colorectal Cancer Liver Metastases: Cost Implications of a Randomized Controlled Trial. J Oncol Pract. 2016;12:e765-74 pubmed publisher..PET-CT was associated with limited clinical benefit and a nonsignificant increased cost. Universal funding of PET-CT in the management of patients with resectable colorectal cancer liver metastases does not seem justified. ..
- Laurie S, Hao D, Leighl N, Goffin J, Khomani A, Gupta A, et al. A phase II trial of dovitinib in previously-treated advanced pleural mesothelioma: The Ontario Clinical Oncology Group. Lung Cancer. 2017;104:65-69 pubmed publisher..One of 12 tumour specimens had low amplification of FGFR-1. Dovitinib has minimal activity in previously-treated MPM. The role of the FGFR pathway in MPM remains unclear. ..