Agnes Y Y Lee

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi Clinical utility of a rapid whole-blood D-dimer assay in patients with cancer who present with suspected acute deep venous thrombosis
    A Y Lee
    McMaster University, Hamilton, Ontario, Canada
    Ann Intern Med 131:417-23. 1999
  2. ncbi Treatment of venous thromboembolism in cancer patients
    A Y Lee
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Thromb Res 102:V195-208. 2001
  3. ncbi Diagnosis and treatment of venous thromboembolism
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton Health Sciences, Henderson Site, 711 Concession Street, Hamilton, Ontario, L8V 1C3, Canada
    Annu Rev Med 53:15-33. 2002
  4. ncbi Randomized comparison of low molecular weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism
    Agnes Y Y Lee
    Hamilton Health Science, Henderson Hospital, Room 9, 90 Wing, 711 Concession St, Hamilton, ON L8V 1C3, Canada
    J Clin Oncol 23:2123-9. 2005
  5. ncbi Development of a clinical prediction rule for risk stratification of recurrent venous thromboembolism in patients with cancer-associated venous thromboembolism
    Martha L Louzada
    Department of Medicine, Division of Hematology, University of Western Ontario, 800 E3637 Commissioners Rd E, London, ON, Canada, N6A 5W9
    Circulation 126:448-54. 2012
  6. ncbi Incidence, risk factors, and outcomes of catheter-related thrombosis in adult patients with cancer
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Clin Oncol 24:1404-8. 2006
  7. ncbi Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 349:146-53. 2003
  8. ncbi Venous thromboembolism and cancer: prevention and therapy
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Vnitr Lek 52:127-8, 130-1. 2006
  9. ncbi The role of low-molecular-weight heparins in treating thrombosis
    Agnes Y Y Lee
    McMaster University, Hamilton Health Sciences, Henderson General Hospital, Ontario, Canada
    J Support Oncol 4:123-4. 2006
  10. ncbi Prophylactic and therapeutic anticoagulation for thrombosis: major issues in oncology
    Marc Carrier
    Division of Hematology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Nat Clin Pract Oncol 6:74-84. 2009

Detail Information

Publications27

  1. ncbi Clinical utility of a rapid whole-blood D-dimer assay in patients with cancer who present with suspected acute deep venous thrombosis
    A Y Lee
    McMaster University, Hamilton, Ontario, Canada
    Ann Intern Med 131:417-23. 1999
    ..Although D-dimer assays have high negative predictive values for the diagnosis of deep venous thrombosis, their accuracy in patients with cancer is uncertain...
  2. ncbi Treatment of venous thromboembolism in cancer patients
    A Y Lee
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Thromb Res 102:V195-208. 2001
    ..The role of inferior vena cava filters in cancer patients remains ill defined but these devices remain the treatment of choice in patients with contraindications for anticoagulant therapy...
  3. ncbi Diagnosis and treatment of venous thromboembolism
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton Health Sciences, Henderson Site, 711 Concession Street, Hamilton, Ontario, L8V 1C3, Canada
    Annu Rev Med 53:15-33. 2002
    ..Aspects of thrombosis treatment that remain controversial include vena caval interruption and the indications for thrombolysis and surgical thromboembolectomy...
  4. ncbi Randomized comparison of low molecular weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism
    Agnes Y Y Lee
    Hamilton Health Science, Henderson Hospital, Room 9, 90 Wing, 711 Concession St, Hamilton, ON L8V 1C3, Canada
    J Clin Oncol 23:2123-9. 2005
    ..Additional studies are warranted to investigate these findings...
  5. ncbi Development of a clinical prediction rule for risk stratification of recurrent venous thromboembolism in patients with cancer-associated venous thromboembolism
    Martha L Louzada
    Department of Medicine, Division of Hematology, University of Western Ontario, 800 E3637 Commissioners Rd E, London, ON, Canada, N6A 5W9
    Circulation 126:448-54. 2012
    ..We performed a retrospective cohort study and a validation study in patients with cancer-associated VTE to derive a clinical prediction rule that stratifies VTE recurrence risk...
  6. ncbi Incidence, risk factors, and outcomes of catheter-related thrombosis in adult patients with cancer
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Clin Oncol 24:1404-8. 2006
    ..We performed a prospective study to examine the incidence, risk factors, and long-term complications of symptomatic catheter-related thrombosis (CRT) in adults with cancer...
  7. ncbi Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ont, Canada
    N Engl J Med 349:146-53. 2003
    ..CONCLUSIONS: In patients with cancer and acute venous thromboembolism, dalteparin was more effective than an oral anticoagulant in reducing the risk of recurrent thromboembolism without increasing the risk of bleeding...
  8. ncbi Venous thromboembolism and cancer: prevention and therapy
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Vnitr Lek 52:127-8, 130-1. 2006
    ..This review will provide an update on the primary prevention and treatment of VTE, as well as prophylaxis for central venous catheters, in patients with malignancy...
  9. ncbi The role of low-molecular-weight heparins in treating thrombosis
    Agnes Y Y Lee
    McMaster University, Hamilton Health Sciences, Henderson General Hospital, Ontario, Canada
    J Support Oncol 4:123-4. 2006
  10. ncbi Prophylactic and therapeutic anticoagulation for thrombosis: major issues in oncology
    Marc Carrier
    Division of Hematology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Nat Clin Pract Oncol 6:74-84. 2009
    ..Newer anticoagulants hold promise in providing more-effective and convenient treatment of VTE in this high-risk population, but further studies are awaited...
  11. ncbi Management of thrombosis in cancer: primary prevention and secondary prophylaxis
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Br J Haematol 128:291-302. 2005
    ..A brief discussion of the potential application of novel anticoagulants in these clinical settings is also included...
  12. ncbi Accuracy and usefulness of a clinical prediction rule and D-dimer testing in excluding deep vein thrombosis in cancer patients
    Marc Carrier
    Thrombosis Program, Division of Hematology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Thromb Res 123:177-83. 2008
    ....
  13. ncbi Treatment and secondary prophylaxis of VTE in the cancer patient: current status
    Agnes Y Y Lee
    Hamilton Civic Hospitals Research Center, Hamilton, Canada
    Pathophysiol Haemost Thromb 33:42-3. 2003
  14. ncbi Risk assessment and primary VTE prevention in the cancer patient
    Mark N Levine
    McMaster University, Faculty of Health Sciences, Hamilton, Canada
    Pathophysiol Haemost Thromb 33:36-41. 2003
  15. ncbi The role of low-molecular-weight heparins in the prevention and treatment of venous thromboembolism in cancer patients
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Pulm Med 9:351-5. 2003
    ..Although the management of cancer patients with venous thromboembolism remains challenging, low-molecular-weight heparins have simplified and improved the prevention and treatment of venous thromboembolism in these high-risk patients...
  16. ncbi Selective D-dimer testing for diagnosis of a first suspected episode of deep venous thrombosis: a randomized trial
    Lori Ann Linkins
    McMaster University, Hamilton, Ontario, Canada
    Ann Intern Med 158:93-100. 2013
    ..Changing the use of testing and the threshold level for a positive test result on the basis of risk for DVT might improve the tradeoff between sensitivity and specificity and reduce the need for testing...
  17. ncbi Treatment of established thrombotic events in patients with cancer
    Agnes Y Y Lee
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Thromb Res 129:S146-53. 2012
    ..Formal studies are needed to address these unmet clinical needs...
  18. ncbi Venous thromboembolism and cancer: risks and outcomes
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Circulation 107:I17-21. 2003
    ..The antineoplastic effects of anticoagulants are being actively investigated with promising preliminary results...
  19. ncbi Anti-thrombotic therapy in cancer patients
    Agnes Y Y Lee
    Department of Medicine, McGill University, Hamilton, ON L8V 1C3, Canada
    Expert Opin Pharmacother 4:2213-20. 2003
    ..The preliminary observations that LMWHs are associated with reduction in cancer mortality make these agents an attractive therapeutic option in oncology patients...
  20. ncbi Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imaging
    Wee Shian Chan
    Department of Medicine, McMaster University, Hamilton, Ont
    CMAJ 185:E194-200. 2013
    ..We evaluated the safety of withholding anticoagulation from pregnant women with suspected deep vein thrombosis following negative serial compression ultrasonography and iliac vein imaging...
  21. ncbi The effects of low molecular weight heparins on venous thromboembolism and survival in patients with cancer
    Agnes Y Y Lee
    Department of Medicine, McMaster University Hamilton, Ontario, Canada
    Thromb Res 120:S121-7. 2007
    ..This review will briefly summarize the data on the treatment of VTE in cancer patients with LMWH and discuss the experimental and clinical data on its possible anticancer effects...
  22. ncbi Prevention of deep vein thrombosis in cancer patients
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Semin Thromb Hemost 33:699-706. 2007
    ..This review will provide a summary of the evidence on the primary prevention of VTE in patients with cancer...
  23. ncbi How we diagnose and treat deep vein thrombosis
    Jack Hirsh
    Henderson Research Centre, and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Blood 99:3102-10. 2002
    ..Several new anticoagulants with theoretical advantages over existing agents are undergoing evaluation in phase 3 studies in patients with venous thromboembolism...
  24. ncbi Epidemiology and management of venous thromboembolism in patients with cancer
    Agnes Y Y Lee
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Thromb Res 110:167-72. 2003
    ..Whether LMWH is capable of modifying tumour biology remains unanswered. Further research is needed to address the many clinical questions in the management of thrombosis in patients with cancer...
  25. ncbi A diagnostic strategy involving a quantitative latex D-dimer assay reliably excludes deep venous thrombosis
    Shannon M Bates
    McMaster University Medical Centre, HSC 3W11, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Ann Intern Med 138:787-94. 2003
    ..Because clinical diagnosis is inaccurate, objective testing is usually considered necessary when patients present with suspected deep venous thrombosis (DVT)...
  26. ncbi Treatment of venous thromboembolism in cancer patients
    Agnes Y Y Lee
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Best Pract Res Clin Haematol 22:93-101. 2009
    ..Newer anticoagulants hold promise in providing more effective and convenient treatment of VTE for this high-risk population, but further studies are awaited...
  27. ncbi Deep vein thrombosis and cancer: survival, recurrence, and anticoagulant choices
    Agnes Y Y Lee
    Dis Mon 51:150-7. 2005