Mark Larché

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi request reprint Immunoregulation by targeting T cells in the treatment of allergy and asthma
    Mark Larché
    Immunology and Allergy Division, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Curr Opin Immunol 18:745-50. 2006
  2. ncbi request reprint Update on the current status of peptide immunotherapy
    Mark Larché
    Department of Medicine, Division of Clinical Immunology and Allergy, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Allergy Clin Immunol 119:906-9. 2007
  3. ncbi request reprint Regulatory T cells in allergy and asthma
    Mark Larché
    Department of Medicine, Division of Clinical Immunology and Allergy, Faculty of Health Sciences, McMaster University, 1200 Main St W, Hamilton, ON, L8N 3Z5, Canada
    Chest 132:1007-14. 2007
  4. doi request reprint Peptide and recombinant immunotherapy
    Mark Larché
    Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, HSC 4H20, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Immunol Allergy Clin North Am 31:377-89, xi. 2011
  5. doi request reprint T cell epitope-based allergy vaccines
    Mark Larché
    Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, HSC 4H20, Hamilton, ON L8N 3Z5, Canada
    Curr Top Microbiol Immunol 352:107-19. 2011
  6. doi request reprint Fel d 1-derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: a randomized, placebo-controlled study
    Deepen Patel
    Cetero Research, Mississauga, Ontario, Canada
    J Allergy Clin Immunol 131:103-9.e1-7. 2013
  7. ncbi request reprint Immunological mechanisms of allergen-specific immunotherapy
    Mark Larché
    Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Nat Rev Immunol 6:761-71. 2006
  8. doi request reprint Immunotherapy with peptides
    D Moldaver
    Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada
    Allergy 66:784-91. 2011
  9. doi request reprint Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma
    Takashi Kinoshita
    Firestone Institute of Respiratory Health, Michael G DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada Department of Medicine, Division of Respirology, Neurology and Rheumatology, Kurume University, Fukuoka, Japan
    J Allergy Clin Immunol 133:696-703. 2014

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Immunoregulation by targeting T cells in the treatment of allergy and asthma
    Mark Larché
    Immunology and Allergy Division, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Curr Opin Immunol 18:745-50. 2006
    ....
  2. ncbi request reprint Update on the current status of peptide immunotherapy
    Mark Larché
    Department of Medicine, Division of Clinical Immunology and Allergy, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Allergy Clin Immunol 119:906-9. 2007
    ..Further studies are required in larger numbers of subjects and with peptides derived from a variety of allergens...
  3. ncbi request reprint Regulatory T cells in allergy and asthma
    Mark Larché
    Department of Medicine, Division of Clinical Immunology and Allergy, Faculty of Health Sciences, McMaster University, 1200 Main St W, Hamilton, ON, L8N 3Z5, Canada
    Chest 132:1007-14. 2007
    ..Further studies are required to precisely define the mechanisms of development and action of these cells, and to identify and evaluate novel targets for the treatment of allergic diseases...
  4. doi request reprint Peptide and recombinant immunotherapy
    Mark Larché
    Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, HSC 4H20, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Immunol Allergy Clin North Am 31:377-89, xi. 2011
    ....
  5. doi request reprint T cell epitope-based allergy vaccines
    Mark Larché
    Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, HSC 4H20, Hamilton, ON L8N 3Z5, Canada
    Curr Top Microbiol Immunol 352:107-19. 2011
    ..Here we review clinical and mechanistic studies associated with peptide immunotherapy targeting allergy to cats or to bee venom. ..
  6. doi request reprint Fel d 1-derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: a randomized, placebo-controlled study
    Deepen Patel
    Cetero Research, Mississauga, Ontario, Canada
    J Allergy Clin Immunol 131:103-9.e1-7. 2013
    ..Allergic rhinoconjunctivitis is an increasingly common source of morbidity, with sensitivity to cats accounting for 10% to 15% of disease burden. Allergy to cats is also a major risk factor for the development of asthma...
  7. ncbi request reprint Immunological mechanisms of allergen-specific immunotherapy
    Mark Larché
    Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Nat Rev Immunol 6:761-71. 2006
    ..This article reviews the development of allergen-specific immunotherapy, our current understanding of its mechanisms of action and its future prospects...
  8. doi request reprint Immunotherapy with peptides
    D Moldaver
    Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada
    Allergy 66:784-91. 2011
    ..Peptide immunotherapy may provide a safe and efficacious alternative to conventional subcutaneous and/or sublingual approaches using native allergen preparations...
  9. doi request reprint Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma
    Takashi Kinoshita
    Firestone Institute of Respiratory Health, Michael G DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada Department of Medicine, Division of Respirology, Neurology and Rheumatology, Kurume University, Fukuoka, Japan
    J Allergy Clin Immunol 133:696-703. 2014
    ..Natural regulatory T (Treg) cells are implicated in the regulation of the inflammatory response in patients with allergic asthma...