Research Topics
| Andre LamySummaryAffiliation: McMaster University Country: Canada Publications
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Detail Information
Publications
Off-pump or on-pump coronary-artery bypass grafting at 30 daysAndre Lamy
Population Health Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada
N Engl J Med 366:1489-97. 2012..The relative benefits and risks of performing coronary-artery bypass grafting (CABG) with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary bypass (on-pump CABG), are not clearly established...- The cost of clopidogrel use in atrial fibrillation in the ACTIVE-A trialAndre Lamy
CADENCE Research Group, Hamilton Health Sciences, Hamilton, Ontario, Canada
Can J Cardiol 28:95-101. 2012..This analysis examined cost implications of adding clopidogrel to aspirin (C+A) for ACTIVE-A patients... 
Outcome of major cardiac injuries at a Canadian trauma centerKhaled Alanezi
Department of Surgery, McMaster University, Hamilton, Ontario, Canada
BMC Surg 2:4. 2002..We compared our outcomes to those of other centers...
A cost comparison of off-pump CABG versus on-pump CABG at one-year: The Canadian off-pump CABG registryAndre Lamy
Department of Surgery, McMaster University, Hamilton, Ontario, Canada
Can J Cardiol 22:699-704. 2006..However, it is uncertain whether the cost savings are sustained over a longer period of time...- The cost implications of the use of telmisartan or ramipril in patients at high risk for vascular events: the ONTARGET studyAndre Lamy
CADENCE Research Group, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada
J Med Econ 14:792-7. 2011..The cost implications of ramipril and telmisartan monotherapy use based on the ONTARGET study are reported here... 
The cost-effectiveness of the use of clopidogrel in acute coronary syndromes in five countries based upon the CURE studyAndre Lamy
Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
Eur J Cardiovasc Prev Rehabil 11:460-5. 2004..The CURE study demonstrated that clopidogrel prevents a range of ischaemic cardiovascular events in patients with Acute Coronary Syndromes (unstable angina or non-ST-segment elevation MI)...- Rationale and design of the coronary artery bypass grafting surgery off or on pump revascularization study: a large international randomized trial in cardiac surgeryAndre Lamy
Population Health Research Institute, Hamilton Health Sciences, McMaster University, Canada
Am Heart J 163:1-6. 2012..Prior trials had few events and relatively short follow-up. There is a need for a large randomized, controlled trial with long-term follow-up to inform both the short- and long-term impact of the 2 approaches to CABG... - Cost implications of the use of ramipril in high-risk patients based on the Heart Outcomes Prevention Evaluation (HOPE) studyAndre Lamy
CADENCE Research Group, McMaster University, Hamilton, Ontario, Canada
Circulation 107:960-5. 2003..In this study, we report the cost implications, in both the United States and Canada, of the use of ramipril after the HOPE study... - The Canadian off-pump coronary artery bypass graft registry: a one-year prospective comparison with on-pump coronary artery bypass graftingA Lamy
McMaster University, Hamilton, Canada
Can J Cardiol 21:1175-81. 2005..The authors sought to examine in-hospital and one-year outcomes of off-pump coronary artery bypass grafting (CABG) and to determine the subgroups of patients most likely to benefit from the off-pump procedure in a regular surgical practice... - Left Atrial Appendage Occlusion Study (LAAOS): results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for strokeJeff S Healey
McMaster University, Hamilton, Ontario, Canada
Am Heart J 150:288-93. 2005..This pilot study assessed the safety and efficacy of left atrial appendage (LAA) occlusion, performed at the time of coronary artery bypass grafting (CABG)... - Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting studyJack C J Sun
Division of Cardiac Surgery, McMaster University, Hamilton, Canada
Am Heart J 160:1178-84. 2010..We performed a pilot study measuring safety and efficacy outcomes of aspirin and clopidogrel therapy after CABG... - Double-blind, placebo-controlled, randomized trial of prophylactic metoprolol for reduction of hospital length of stay after heart surgery: the beta-Blocker Length Of Stay (BLOS) studyStuart J Connolly
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Am Heart J 145:226-32. 2003..No previous trials have been primarily directed at demonstrating that the use of drugs that prevent AF would shorten length of stay and reduce the costs of postoperative care... - Early mortality from off-pump and on-pump coronary bypass surgery in Canada: a comparison of the STS and the EuroSCORE risk prediction algorithmsForough Farrokhyar
McMaster University, Hamilton, Canada
Can J Cardiol 23:879-83. 2007.... - Left Atrial Appendage Occlusion Study (LAAOS): a randomized clinical trial of left atrial appendage occlusion during routine coronary artery bypass graft surgery for long-term stroke preventionEugene Crystal
McMaster University, Hamilton, Ontario, Canada
Am Heart J 145:174-8. 2003..CONCLUSIONS: The clinical trial designed to evaluate LAA occlusion at the time of routine CABG surgery is currently in the pilot phase... - Antithrombotic management of patients with prosthetic heart valves: current evidence and future trendsJack C J Sun
Division of Cardiac Surgery, McMaster University, Hamilton, ON, Canada
Lancet 374:565-76. 2009.... - Economic evaluation of the MEDENOX trial: a Canadian perspective. Medical Patients with EnoxaparinAndre Lamy
CADENCE Research Group and Faculty of Health Sciences, McMaster University, Hamilton, Ontario
Can Respir J 9:169-77. 2002..To perform an economic evaluation of the Prophylaxis in Medical Patients with Enoxaparin (MEDENOX) trial from a Canadian perspective... - Should aspirin be discontinued before coronary artery bypass surgery?Jack C J Sun
Division of Cardiac Surgery, McMaster University, Hamilton, Canada
Circulation 112:e85-90. 2005 - Perivascular adipose tissue modulates vascular function in the human internal thoracic arteryYu Jing Gao
Department of Anaesthesia, McMaster University, Hamilton, Ontario, Canada
J Thorac Cardiovasc Surg 130:1130-6. 2005..The purpose of the present study was to examine whether this vasodilator is also present in human internal thoracic arteries... - Canadian Registry of ICD Implant Testing procedures (CREDIT): current practice, risks, and costs of intraoperative defibrillation testingJeff S Healey
The Population Health Research Institute, McMaster University, Hamilton, Canada
J Cardiovasc Electrophysiol 21:177-82. 2010..There is uncertainty about the proper role of defibrillation testing (DT) at the time of implantable cardioverter defibrillator (ICD) insertion... - Randomized trial of fondaparinux versus heparin to prevent graft failure after coronary artery bypass grafting: the Fonda CABG studyJack C J Sun
Division of Cardiac Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Thromb Thrombolysis 32:378-85. 2011..Fondaparinux appears to be a safe alternative to heparin after CABG and it is feasible to conduct a definitive RCT using CT angiography to evaluate the effect of fondaparinux treatment on graft patency... - Cost comparison of four revascularisation procedures for the treatment of multivessel coronary artery diseaseXiaoyin Wang
McMaster University, Department of Surgery, Division of Cardiac Surgery, Hamilton, Ontario, Canada
J Med Econ 11:119-34. 2008.... - Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activationIrem Mueed
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
J Thorac Cardiovasc Surg 135:131-8. 2008..We examined the roles of isoprostanes and prostanoid receptors selective for thromboxane A2 in the vasoconstriction of human radial arteries... - The effect of oxygenator membranes on blood: a comparison of two oxygenators in open-heart surgeryJoseph Noora
McMaster University, Hamilton, Ontario, Canada
Perfusion 18:313-20. 2003..The Affinity NT had the smaller transmembrane pressure drop of the two... - Para-aortic arch abscess secondary to Staphylococcus aureus pneumoniaKaren K Koo
Department of Critical Care Medicine, McMaster University, Hamilton, Canada
Can J Cardiol 25:233-6. 2009..The patient was successfully managed nonsurgically with computed tomography-guided drainage and intravenous antibiotics... - F-18-fluorodeoxyglucose positron emission tomography imaging-assisted management of patients with severe left ventricular dysfunction and suspected coronary disease: a randomized, controlled trial (PARR-2)Rob S B Beanlands
National Cardiac PET Centre, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Am Coll Cardiol 50:2002-12. 2007..We conducted a randomized trial to assess the effectiveness of F-18-fluorodeoxyglucose (FDG) positron emission tomography (PET)-assisted management in patients with severe ventricular dysfunction and suspected coronary disease... - Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevationWilliam S Weintraub
Emory University, Atlanta, Georgia, USA
J Am Coll Cardiol 45:838-45. 2005..We sought to evaluate the long-term cost-effectiveness of clopidogrel for up to one year after an acute coronary syndrome (ACS) without ST-segment elevation... - Long-term cost-effectiveness of early and sustained clopidogrel therapy for up to 1 year in patients undergoing percutaneous coronary intervention after presenting with acute coronary syndromes without ST-segment elevationElizabeth M Mahoney
New England Research Institutes, Watertown, MA 02472, USA
Am Heart J 151:219-27. 2006..We evaluated the long-term cost-effectiveness of clopidogrel use for up to 1 year using patient-level outcomes and resource use from PCI-CURE, and estimates of life expectancy gains based on external sources... - Positron emission tomography and recovery following revascularization (PARR-1): the importance of scar and the development of a prediction rule for the degree of recovery of left ventricular functionRob S B Beanlands
Cardiac PET Centre, Divisions of Cardiology and Cardiac Surgery, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada
J Am Coll Cardiol 40:1735-43. 2002....