Bradley C Johnston

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. doi request reprint New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures
    Bradley C Johnston
    Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Epidemiol 65:817-26. 2012
  2. pmc Water and sanitation infrastructure for health: The impact of foreign aid
    Marianne J Botting
    Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Canada
    Global Health 6:12. 2010
  3. doi request reprint Measurement issues in trials of pediatric acute diarrheal diseases: a systematic review
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Pediatrics 126:e222-31. 2010
  4. doi request reprint Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Department of Anesthesia, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Stanford Prevention Research Center, Department of Medicine, Stanford University, 1265 Welch Road, Stanford, California, USA, 94305 Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada, M5G 1X8 Electronic address
    J Clin Epidemiol 67:560-70. 2014
  5. doi request reprint Do clinicians understand the size of treatment effects? A randomized survey across 8 countries
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine Johnston, Crawford, The Hospital for Sick Children, University of Toronto, Toronto, Ont Institute of Health Policy, Management and Evaluation Johnston, Dalla Lana School of Public Health, University of Toronto, Toronto, Ont Child Health Evaluative Sciences Johnston, The Hospital for Sick Children Research Institute, Toronto, Ont Iberoamerican Cochrane Center Alonso Coello, Dalmau, Biomedical Research Institute Sant Pau, CIBER Epidemiologiay Salud Publica, Barcelona, Spain Departments of Critical Care and Medicine Friedrich, St Michael s Hospital, Toronto, Ont Department of Medicine and Interdepartmental Division of Critical Care Friedrich, University of Toronto, Toronto, Ont Departments of Medicine and Biomedical and Health Informatics Mustafa, University of Missouri Kansas City, Kansas City, Mo Department of Clinical Epidemiology and Biostatistics Mustafa, Tikkinen, Neumann, AKL, Thabane, Guyatt, McMaster University, Hamilton, Ont Departments of Urology and Public Health Tikkinen, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland Department of Internal Medicine Neumann, Pontificia Universidad Catolica de Chile, France
    CMAJ 188:25-32. 2016
  6. doi request reprint Minimally important difference estimates and methods: a protocol
    Bradley C Johnston
    Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada Child Health Evaluative Sciences, The Research Institute, The Hospital for Sick Children, Hospital for Sick Children, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMJ Open 5:e007953. 2015
  7. doi request reprint Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide
    Elie A Akl
    Department of Internal Medicine, American University of Beirut, Beirut, Lebanon Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMJ Open 5:e008431. 2015
  8. pmc Patient-reported outcomes in meta-analyses-part 2: methods for improving interpretability for decision-makers
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:211. 2013
  9. ncbi request reprint Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis
    Bradley C Johnston
    The Hospital for Sick Children Research Institute, Room 2420, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Ann Intern Med 157:878-88. 2012
  10. doi request reprint Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey
    Elie A Akl
    Department of Internal Medicine, American University of Beirut, Beirut, Lebanon Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMJ Open 5:e009368. 2015

Collaborators

Detail Information

Publications21

  1. doi request reprint New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures
    Bradley C Johnston
    Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Epidemiol 65:817-26. 2012
    ..Approaches suggested thus far omit studies that used instruments without an established MID. We describe an approach that addresses this limitation...
  2. pmc Water and sanitation infrastructure for health: The impact of foreign aid
    Marianne J Botting
    Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Canada
    Global Health 6:12. 2010
    ..The actual impact of this assistance on increasing population access to improved water and sanitation and reducing child mortality has not been examined...
  3. doi request reprint Measurement issues in trials of pediatric acute diarrheal diseases: a systematic review
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Pediatrics 126:e222-31. 2010
    ..Worldwide, diarrheal diseases rank second among conditions that afflict children. Despite the disease burden, there is limited consensus on how to define and measure pediatric acute diarrhea in trials...
  4. doi request reprint Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Department of Anesthesia, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Stanford Prevention Research Center, Department of Medicine, Stanford University, 1265 Welch Road, Stanford, California, USA, 94305 Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada, M5G 1X8 Electronic address
    J Clin Epidemiol 67:560-70. 2014
    ..We extend this approach to meta-analyses including trials that use different instruments to measure the same construct...
  5. doi request reprint Do clinicians understand the size of treatment effects? A randomized survey across 8 countries
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine Johnston, Crawford, The Hospital for Sick Children, University of Toronto, Toronto, Ont Institute of Health Policy, Management and Evaluation Johnston, Dalla Lana School of Public Health, University of Toronto, Toronto, Ont Child Health Evaluative Sciences Johnston, The Hospital for Sick Children Research Institute, Toronto, Ont Iberoamerican Cochrane Center Alonso Coello, Dalmau, Biomedical Research Institute Sant Pau, CIBER Epidemiologiay Salud Publica, Barcelona, Spain Departments of Critical Care and Medicine Friedrich, St Michael s Hospital, Toronto, Ont Department of Medicine and Interdepartmental Division of Critical Care Friedrich, University of Toronto, Toronto, Ont Departments of Medicine and Biomedical and Health Informatics Mustafa, University of Missouri Kansas City, Kansas City, Mo Department of Clinical Epidemiology and Biostatistics Mustafa, Tikkinen, Neumann, AKL, Thabane, Guyatt, McMaster University, Hamilton, Ont Departments of Urology and Public Health Tikkinen, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland Department of Internal Medicine Neumann, Pontificia Universidad Catolica de Chile, France
    CMAJ 188:25-32. 2016
    ....
  6. doi request reprint Minimally important difference estimates and methods: a protocol
    Bradley C Johnston
    Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada Child Health Evaluative Sciences, The Research Institute, The Hospital for Sick Children, Hospital for Sick Children, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMJ Open 5:e007953. 2015
    ....
  7. doi request reprint Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide
    Elie A Akl
    Department of Internal Medicine, American University of Beirut, Beirut, Lebanon Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMJ Open 5:e008431. 2015
    ....
  8. pmc Patient-reported outcomes in meta-analyses-part 2: methods for improving interpretability for decision-makers
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:211. 2013
    ..g. where the mean in the treatment group is divided by the mean in the control group, the ratio of means is 1.27, representing a 27% relative reduction in the mean depression score). ..
  9. ncbi request reprint Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis
    Bradley C Johnston
    The Hospital for Sick Children Research Institute, Room 2420, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Ann Intern Med 157:878-88. 2012
    ..Antibiotic treatment may disturb the resistance of gastrointestinal flora to colonization. This may result in complications, the most serious of which is Clostridium difficile–associated diarrhea (CDAD)...
  10. doi request reprint Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey
    Elie A Akl
    Department of Internal Medicine, American University of Beirut, Beirut, Lebanon Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMJ Open 5:e009368. 2015
    ..To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias...
  11. doi request reprint Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Canada, L8S 4K1
    J Clin Epidemiol 66:1014-1021.e1. 2013
    ..No methods directly address the impact of missing participant data for continuous outcomes in systematic reviews on risk of bias...
  12. doi request reprint Conceptual framework for health-related quality of life assessment in acute gastroenteritis
    Bradley C Johnston
    Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 56:280-9. 2013
    ....
  13. pmc Patient-reported outcomes in meta-analyses--Part 1: assessing risk of bias and combining outcomes
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:109. 2013
    ....
  14. doi request reprint GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    J Clin Epidemiol 66:173-83. 2013
    ..We outline the merits and limitations of each alternative and provide guidance for meta-analysts and guideline developers...
  15. doi request reprint Although not consistently superior, the absolute approach to framing the minimally important difference has advantages over the relative approach
    Yuqing Zhang
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main St West, Hamilton, Ontario, Canada L8S 4K1
    J Clin Epidemiol 68:888-94. 2015
    ..Using studies that established minimal important difference (MID) using anchor-based methods, we set out to address the relative merits of absolute and relative changes in establishing an instrument's MID...
  16. doi request reprint Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis
    Bradley C Johnston
    Hospital for Sick Children Research Institute, Toronto, Ontario, Canada2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada3Department of Clinical Epidemiology and Biostatistics, McMaster University, Hami
    JAMA 312:923-33. 2014
    ..Many claims have been made regarding the superiority of one diet or another for inducing weight loss. Which diet is best remains unclear...
  17. pmc Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Health Qual Life Outcomes 8:116. 2010
    ..This approach provides a potential solution to both the statistical and interpretational problems of existing methods...
  18. pmc Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers
    Elie A Akl
    Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
    PLoS ONE 8:e57132. 2013
    ..Systematic reviewer authors intending to include all randomized participants in their meta-analyses need to make assumptions about the outcomes of participants with missing data...
  19. pmc Recent advances in patient and proxy-reported quality of life research
    Kristofer Bandayrel
    Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada
    Health Qual Life Outcomes 12:110. 2014
    ..This review provides a summary of studies describing recent methodological advances and innovations in HRQoL felt to be of relevance to clinicians and researchers...
  20. pmc Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 7:e39471. 2012
    ..However, no previous studies have explored how many trials and events are required to ensure stable and reliable I(2) estimates, or how 95% CIs perform as evidence accumulates...
  21. ncbi request reprint Probiotics for the prevention of pediatric antibiotic-associated diarrhea
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, 2C12, Hamilton, Ontario, Canada, L8N 3Z5
    Cochrane Database Syst Rev 11:CD004827. 2011
    ..Probiotics may prevent antibiotic-associated diarrhea (AAD) via restoration of the gut microflora. Antibiotics are prescribed frequently in children and AAD is common in this population...