Bradley C Johnston

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. pmc Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Health Qual Life Outcomes 8:116. 2010
  2. doi request reprint New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures
    Bradley C Johnston
    Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Epidemiol 65:817-26. 2012
  3. pmc Water and sanitation infrastructure for health: The impact of foreign aid
    Marianne J Botting
    Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Canada
    Global Health 6:12. 2010
  4. doi request reprint Measurement issues in trials of pediatric acute diarrheal diseases: a systematic review
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Pediatrics 126:e222-31. 2010
  5. ncbi request reprint Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Department of Anesthesia, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Stanford Prevention Research Center, Department of Medicine, Stanford University, 1265 Welch Road, Stanford, California, USA, 94305 Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada, M5G 1X8 Electronic address
    J Clin Epidemiol 67:560-70. 2014
  6. pmc Patient-reported outcomes in meta-analyses --Part 2: methods for improving interpretability for decision-makers
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:211. 2013
  7. pmc Patient-reported outcomes in meta-analyses--Part 1: assessing risk of bias and combining outcomes
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:109. 2013
  8. ncbi request reprint Conceptual framework for health-related quality of life assessment in acute gastroenteritis
    Bradley C Johnston
    Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 56:280-9. 2013
  9. ncbi request reprint Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis
    Bradley C Johnston
    The Hospital for Sick Children Research Institute, Room 2420, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Ann Intern Med 157:878-88. 2012
  10. doi request reprint Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Canada, L8S 4K1
    J Clin Epidemiol 66:1014-1021.e1. 2013

Collaborators

Detail Information

Publications14

  1. pmc Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Health Qual Life Outcomes 8:116. 2010
    ..This approach provides a potential solution to both the statistical and interpretational problems of existing methods...
  2. doi request reprint New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures
    Bradley C Johnston
    Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Epidemiol 65:817-26. 2012
    ..Approaches suggested thus far omit studies that used instruments without an established MID. We describe an approach that addresses this limitation...
  3. pmc Water and sanitation infrastructure for health: The impact of foreign aid
    Marianne J Botting
    Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Canada
    Global Health 6:12. 2010
    ..The actual impact of this assistance on increasing population access to improved water and sanitation and reducing child mortality has not been examined...
  4. doi request reprint Measurement issues in trials of pediatric acute diarrheal diseases: a systematic review
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Pediatrics 126:e222-31. 2010
    ..Worldwide, diarrheal diseases rank second among conditions that afflict children. Despite the disease burden, there is limited consensus on how to define and measure pediatric acute diarrhea in trials...
  5. ncbi request reprint Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Department of Anesthesia, McMaster University, 1200 Main St West, Hamilton, Ontario, Canada, L8S 4K1 Stanford Prevention Research Center, Department of Medicine, Stanford University, 1265 Welch Road, Stanford, California, USA, 94305 Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada, M5G 1X8 Electronic address
    J Clin Epidemiol 67:560-70. 2014
    ..We extend this approach to meta-analyses including trials that use different instruments to measure the same construct...
  6. pmc Patient-reported outcomes in meta-analyses --Part 2: methods for improving interpretability for decision-makers
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:211. 2013
    ..g. where the mean in the treatment group is divided by the mean in the control group, the ratio of means is 1.27, representing a 27% relative reduction in the mean depression score). ..
  7. pmc Patient-reported outcomes in meta-analyses--Part 1: assessing risk of bias and combining outcomes
    Bradley C Johnston
    Department of Anesthesia and Pain Medicine, and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    Health Qual Life Outcomes 11:109. 2013
    ....
  8. ncbi request reprint Conceptual framework for health-related quality of life assessment in acute gastroenteritis
    Bradley C Johnston
    Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Gastroenterol Nutr 56:280-9. 2013
    ....
  9. ncbi request reprint Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis
    Bradley C Johnston
    The Hospital for Sick Children Research Institute, Room 2420, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Ann Intern Med 157:878-88. 2012
    ..Antibiotic treatment may disturb the resistance of gastrointestinal flora to colonization. This may result in complications, the most serious of which is Clostridium difficile–associated diarrhea (CDAD)...
  10. doi request reprint Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers
    Shanil Ebrahim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, Hamilton, Canada, L8S 4K1
    J Clin Epidemiol 66:1014-1021.e1. 2013
    ..No methods directly address the impact of missing participant data for continuous outcomes in systematic reviews on risk of bias...
  11. doi request reprint GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    J Clin Epidemiol 66:173-83. 2013
    ..We outline the merits and limitations of each alternative and provide guidance for meta-analysts and guideline developers...
  12. pmc Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers
    Elie A Akl
    Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
    PLoS ONE 8:e57132. 2013
    ..Systematic reviewer authors intending to include all randomized participants in their meta-analyses need to make assumptions about the outcomes of participants with missing data...
  13. pmc Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 7:e39471. 2012
    ..However, no previous studies have explored how many trials and events are required to ensure stable and reliable I(2) estimates, or how 95% CIs perform as evidence accumulates...
  14. ncbi request reprint Probiotics for the prevention of pediatric antibiotic-associated diarrhea
    Bradley C Johnston
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, 2C12, Hamilton, Ontario, Canada, L8N 3Z5
    Cochrane Database Syst Rev 11:CD004827. 2011
    ..Probiotics may prevent antibiotic-associated diarrhea (AAD) via restoration of the gut microflora. Antibiotics are prescribed frequently in children and AAD is common in this population...