Pieter L Jager

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi Combined vertebral fracture assessment and bone mineral density measurement: a patient-friendly new tool with an important impact on the Canadian Risk Fracture Classification
    Pieter L Jager
    Department of Nuclear Medicine, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
    Can Assoc Radiol J 61:194-200. 2010
  2. ncbi 6-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications
    Pieter L Jager
    Department of Nuclear Medicine, Hamilton Health Sciences McMaster University, Hamilton, Ontario, Canada
    J Nucl Med 49:573-86. 2008
  3. ncbi PET/CT using ¹⁸F-FDOPA provides improved staging of carcinoid tumor patients in a Canadian setting
    Valerie N Yakemchuk
    Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada
    Nucl Med Commun 33:322-30. 2012
  4. ncbi Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells
    Oliver C Neels
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cancer Res 68:7183-90. 2008
  5. ncbi Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography
    Klaas P Koopmans
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    J Clin Oncol 26:1489-95. 2008
  6. ncbi The therapeutic challenge of a nonresectable solitary fibrous tumor in a hypoglycemic patient
    Jaap de Boer
    Department of Medical Oncology, University Medical Centre Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands
    Int J Clin Oncol 11:478-81. 2006
  7. ncbi 18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment
    Ali Agool
    Department of Nuclear Medicine and Molecular Imaging, University of Groningen, Groningen, The Netherlands
    J Nucl Med 47:1592-8. 2006
  8. ncbi Myocardial perfusion quantification in patients suspected of cardiac syndrome X with positive and negative exercise testing: a [13N]ammonia positron emission tomography study
    Jessica de Vries
    Faculty of Medicine, University Medical Center Groningen and University of Groningen, The Netherlands
    Nucl Med Commun 27:791-4. 2006
  9. ncbi Staging of carcinoid tumours with 18F-DOPA PET: a prospective, diagnostic accuracy study
    Klaas P Koopmans
    Department of Nuclear Medicine and Molecular Imaging, University Medical Centre Groningen, Groningen, Netherlands
    Lancet Oncol 7:728-34. 2006
  10. ncbi 18F-fluorodeoxythymidine PET for evaluating the response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcomas
    Lukas B Been
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Nucl Med 48:367-72. 2007

Collaborators

  • Valerie N Yakemchuk
  • R H J A Slart
  • Alexandra Papaioannou
  • P H Elsinga
  • Ha T T Phan
  • J J Bax
  • K Ishiwata
  • Marinke Westerterp
  • Klaas P Koopmans
  • Henderik L van Westreenen
  • Ido P Kema
  • Elisabeth G E de Vries
  • Oliver C Neels
  • Lukas B Been
  • Thera P Links
  • Wim J Sluiter
  • Adrienne H Brouwers
  • Aren van Waarde
  • Henk Groen
  • Anouk N A van der Horst-Schrivers
  • John Th M Plukker
  • Albert J H Suurmeijer
  • Hendrik M van Dullemen
  • David C P Cobben
  • Robin P F Dullaart
  • Karin M van Tol
  • Liesbeth M Schreurs
  • John T M Plukker
  • Jessica de Vries
  • Jaap de Boer
  • Ali Agool
  • Theo Wiggers
  • Harald J Hoekstra
  • Marnix G E H Lam
  • Thi T H Phan
  • D Albertus Piers
  • Janine Doorduin
  • Koen Vanghillewe
  • Gooitzen M van Dam
  • Christian C Verhoef
  • Bareld B Pultrum
  • Laya Vercauteren
  • Rudi A J O Dierckx
  • Erik J van der Jagt
  • Jan Willem B de Groot
  • Hetty Timmer-Bosscha
  • Robert J van Ginkel
  • Bart W Schot
  • Rudi A Dierckx
  • A N Machteld Wymenga
  • Jan P Schouten
  • Mike J L Dejongste
  • Winette T A van der Graaf
  • H Marike Boezen
  • Peter Nieboer
  • Gillian A J Jessurun
  • Klaas Hoogenberg
  • Elisabeth Pras
  • Edo Vellenga
  • Dirk T Sleijfer
  • Michiel J Staal
  • Eef G W M Lentjes
  • J Jan B van Lanschot
  • Peter P van Rijk
  • Jelle Wesseling
  • Cornelis J M Lips
  • Anouk N Van der Horst-Schrivers
  • Carolien J M Verhoogt
  • Gerrit W Sloof
  • Eric J van der Jagt
  • Marjolijn N de Hooge
  • Elisabeth G de Vries
  • Emile F I Comans
  • Pierre A M Heeren
  • John Th Plukker
  • John M H de Klerk
  • Bruce H Wolffenbuttel
  • Jan Pruim

Detail Information

Publications34

  1. ncbi Combined vertebral fracture assessment and bone mineral density measurement: a patient-friendly new tool with an important impact on the Canadian Risk Fracture Classification
    Pieter L Jager
    Department of Nuclear Medicine, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
    Can Assoc Radiol J 61:194-200. 2010
    ..Our purpose was to determine the added value of VFA and its impact on the Canadian fracture risk classification using data from a Dutch academic cohort...
  2. ncbi 6-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications
    Pieter L Jager
    Department of Nuclear Medicine, Hamilton Health Sciences McMaster University, Hamilton, Ontario, Canada
    J Nucl Med 49:573-86. 2008
    ..In the remaining conditions, the initial experience with 18F-DOPA PET indicates that it seems to be less valuable, but further study is required...
  3. ncbi PET/CT using ¹⁸F-FDOPA provides improved staging of carcinoid tumor patients in a Canadian setting
    Valerie N Yakemchuk
    Department of Nuclear Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada
    Nucl Med Commun 33:322-30. 2012
    ..This study assessed the diagnostic accuracy of 6-[¹⁸F]fluoro-3,4-dihydroxyphenylalanine (¹⁸F-FDOPA) PET/CT in neuroendocrine tumors...
  4. ncbi Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells
    Oliver C Neels
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cancer Res 68:7183-90. 2008
    ..This could be a consequence of the serotonin saturation of BON cells in the in vivo model...
  5. ncbi Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography
    Klaas P Koopmans
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    J Clin Oncol 26:1489-95. 2008
    ..To evaluate and compare diagnostic sensitivity of positron emission tomography (PET) scanning in carcinoid and islet cell tumor patients with a serotonin and a catecholamine precursor as tracers...
  6. ncbi The therapeutic challenge of a nonresectable solitary fibrous tumor in a hypoglycemic patient
    Jaap de Boer
    Department of Medical Oncology, University Medical Centre Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands
    Int J Clin Oncol 11:478-81. 2006
    ..Our report highlights several important issues in the management of the patient with a nonresectable solitary fibrous tumor with severe episodes of hypoglycemia due to NICTH...
  7. ncbi 18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment
    Ali Agool
    Department of Nuclear Medicine and Molecular Imaging, University of Groningen, Groningen, The Netherlands
    J Nucl Med 47:1592-8. 2006
    ..CONCLUSION: 18F-FLT PET can be used to visualize the proliferative activity of the bone marrow compartment and may be helpful to distinguish separate hematologic disorders...
  8. ncbi Myocardial perfusion quantification in patients suspected of cardiac syndrome X with positive and negative exercise testing: a [13N]ammonia positron emission tomography study
    Jessica de Vries
    Faculty of Medicine, University Medical Center Groningen and University of Groningen, The Netherlands
    Nucl Med Commun 27:791-4. 2006
    ..001 for both), compared to normal controls. CONCLUSION: PET demonstrates a reduced coronary flow reserve in patients suspected of syndrome X, irrespective of the EST findings...
  9. ncbi Staging of carcinoid tumours with 18F-DOPA PET: a prospective, diagnostic accuracy study
    Klaas P Koopmans
    Department of Nuclear Medicine and Molecular Imaging, University Medical Centre Groningen, Groningen, Netherlands
    Lancet Oncol 7:728-34. 2006
    ....
  10. ncbi 18F-fluorodeoxythymidine PET for evaluating the response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcomas
    Lukas B Been
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Nucl Med 48:367-72. 2007
    ..In this study, the response to HILP was measured by PET with (18)F-fluorodeoxythymidine ((18)F-FLT)...
  11. ncbi Detection of bone metastases in thyroid cancer patients: bone scintigraphy or 18F-FDG PET?
    Ha T T Phan
    Department of Nuclear Medicine and Molecular Imaging, University Medical Centre Groningen, The Netherlands
    Nucl Med Commun 28:597-602. 2007
    ..The purpose of this retrospective study was to evaluate the performance of bone scans in comparison with FDG PET in the detection of bone metastases in patients with differentiated thyroid cancer (DTC)...
  12. ncbi The follow-up of patients with differentiated thyroid cancer and undetectable thyroglobulin (Tg) and Tg antibodies during ablation
    Ha T T Phan
    Department of Nuclear Medicine and Molecular Imaging, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur J Endocrinol 158:77-83. 2008
    ....
  13. ncbi The diagnostic value of 124I-PET in patients with differentiated thyroid cancer
    Ha T T Phan
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Nucl Med Mol Imaging 35:958-65. 2008
    ....
  14. ncbi 18F-dihydroxyphenylalanine PET in patients with biochemical evidence of medullary thyroid cancer: relation to tumor differentiation
    Klaas P Koopmans
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 49:524-31. 2008
    ..Therefore, the value of 18F-dihydroxyphenylalanine PET (18F-DOPA PET), 18F-FDG PET, (99m)Tc-V-di-mercaptosulfuricacid (DMSA-V) scintigraphy, and MRI or CT was studied...
  15. ncbi Better assessment of nodal metastases by PET/CT fusion compared to side-by-side PET/CT in oesophageal cancer
    Liesbeth M Schreurs
    Deparments of Surgical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Anticancer Res 28:1867-73. 2008
    ..Recently, positron emission tomography/computed tomography (PET/CT) has been introduced in the staging of oesophageal cancer. The impact of PET/CT fusion in comparison with side-by-side PET/CT in these tumours, was analyzed...
  16. ncbi Comparison of 11C-methionine PET and 18F-fluorodeoxyglucose PET in differentiated thyroid cancer
    Ha T T Phan
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University Hospital of Groningen, The Netherlands
    Nucl Med Commun 29:711-6. 2008
    ....
  17. ncbi Iodine-123 metaiodobenzylguanidine scintigraphy in localising phaeochromocytomas--experience and meta-analysis
    Anouk N A van der Horst-Schrivers
    Department of Endocrinology, University Medical Center Groningen, Groningen, The Netherlands
    Anticancer Res 26:1599-604. 2006
    ..The accuracy of I-123 MIBG scintigraphy was determined by evaluating our own I-123 MIBG scans and performing a meta-analysis...
  18. ncbi Prediction of functional recovery after revascularization in patients with coronary artery disease and left ventricular dysfunction by gated FDG-PET
    Riemer H J A Slart
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Cardiol 13:210-9. 2006
    ....
  19. ncbi Imatinib mesylate for the treatment of gastrointestinal stromal tumours: best monitored with FDG PET
    Pieter L Jager
    PET Center Department of Nuclear Medicine, University Hospital Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands
    Nucl Med Commun 25:433-8. 2004
    ..The new anti-cancer drug imatinib mesylate inhibits the tyrosine kinase growth factor receptor, c-KIT, and has shown spectacular activity in patients with gastrointestinal stromal tumours (GISTs)...
  20. ncbi [18F]FLT-PET in oncology: current status and opportunities
    Lukas B Been
    PET Center, Groningen University Hospital, Groningen, RB, The Netherlands
    Eur J Nucl Med Mol Imaging 31:1659-72. 2004
    ..The opportunities provided by, and the limitations of, [18F]FLT as a proliferation tracer are addressed in this review, and directions are given for further research, taking into account the strong and weak points of the new tracer...
  21. ncbi Positron emission tomography with F-18-fluorodeoxyglucose in a combined staging strategy of esophageal cancer prevents unnecessary surgical explorations
    Henderik L van Westreenen
    Department of Surgical Oncology, University Hospital Groningen, Groningen, The Netherlands
    J Gastrointest Surg 9:54-61. 2005
    ..The addition of FDG-PET may have reduced the rate of unnecessary surgery in this group of patients...
  22. ncbi Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer: no additional value of higher scan dose
    Thi T H Phan
    Department of Endocrinology, University Hospital Groningen, The Netherlands
    Ann Nucl Med 18:641-6. 2004
    ..The combination of a low-dose diagnostic I-131 scan using only 74 MBq combined with a serum Tg level measurement proved sufficient for correct clinical decision making regarding whether the patient requires additional I-131 therapy...
  23. ncbi Comparison of 18F-FLT PET and 18F-FDG PET in esophageal cancer
    Henderik L van Westreenen
    Department of Surgical Oncology, University Medical Center, Groningen, The Netherlands
    J Nucl Med 46:400-4. 2005
    ..18F-FLT scans show more false-negative findings and fewer false-positive findings than do 18F-FDG scans. Uptake of 18F-FDG or 18F-FLT did not correlate with proliferation...
  24. ncbi Comparison of 99mTc-sestamibi/18FDG DISA SPECT with PET for the detection of viability in patients with coronary artery disease and left ventricular dysfunction
    Riemer H J A Slart
    Department of Nuclear Medicine and Molecular Imaging, Groningen University Medical Center, Hanzeplein 1, P O Box 30001, 9700 RB, Groningen, The Netherlands
    Eur J Nucl Med Mol Imaging 32:972-9. 2005
    ..In the present study, DISA SPECT was compared with positron emission tomography (PET) for the detection of myocardial viability in normal and dysfunctional left ventricular (LV) myocardium...
  25. ncbi Carcinoid crisis after injection of 6-18F-fluorodihydroxyphenylalanine in a patient with metastatic carcinoid
    Klaas P Koopmans
    Department of Nuclear Medicine and PET Center, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 46:1240-3. 2005
    ..Octreotide can be used for treatment and should be available. Tracer injection should be slow...
  26. ncbi Prognostic value of the standardized uptake value in esophageal cancer
    Henderik L van Westreenen
    Department of Surgery, University Hospital Groningen, Hanzeplein 1, PO Box 30001, 9700 RB Groningen, The Netherlands
    AJR Am J Roentgenol 185:436-40. 2005
    ..CONCLUSION: SUV can be used to predict resectability; however, SUV is not an independent factor that can be used to assess survival in patients with esophageal cancer...
  27. ncbi Repeated [131I]metaiodobenzylguanidine therapy in two patients with malignant pheochromocytoma
    Marnix G E H Lam
    University Medical Center Utrecht, Department of Nuclear Medicine, P O Box 85500, 3508 GA Utrecht, The Netherlands
    J Clin Endocrinol Metab 90:5888-95. 2005
    ..We present our experience with multiple intermediate-dosage [131I]MIBG therapy instead of single high-dosage therapy...
  28. ncbi Synchronous primary neoplasms detected on 18F-FDG PET in staging of patients with esophageal cancer
    Henderik L van Westreenen
    Department of Surgery, University of Groningen and University Medical Center Groningen, The Netherlands
    J Nucl Med 46:1321-5. 2005
    ..5% of patients with esophageal cancer. Sites of pathologic (18)F-FDG uptake should be confirmed by dedicated additional investigations before treatment, because synchronous neoplasms may mimic metastases...
  29. ncbi Esophageal cancer: CT, endoscopic US, and FDG PET for assessment of response to neoadjuvant therapy--systematic review
    Marinke Westerterp
    Department of Surgery, Academic Medical Center, University of Amsterdam, Suite G4 130, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Radiology 236:841-51. 2005
    ....
  30. ncbi Imaging techniques in nuclear cardiology for the assessment of myocardial viability
    Riemer H J A Slart
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
    Int J Cardiovasc Imaging 22:63-80. 2006
    ..Evaluation of the clinical role of these creative new possibilities warrants investigation...
  31. ncbi Comparison of sigma-ligands and metabolic PET tracers for differentiating tumor from inflammation
    Aren van Waarde
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center of Groningen, University of Groningen, The Netherlands
    J Nucl Med 47:150-4. 2006
    ..Increased glucose metabolism of inflammatory tissues is the main source of false-positive (18)F-FDG PET findings in oncology...
  32. ncbi Prediction of functional recovery after revascularization in patients with chronic ischaemic left ventricular dysfunction: head-to-head comparison between 99mTc-sestamibi/18F-FDG DISA SPECT and 13N-ammonia/ 18F-FDG PET
    Riemer H J A Slart
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, P O Box 30001, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
    Eur J Nucl Med Mol Imaging 33:716-23. 2006
    ..The aim of this study was to compare the diagnostic performance of PET and DISA SPECT for the prediction of improvement in regional and global LV function as well as LV reverse remodelling after revascularization...
  33. ncbi Optimal imaging of patients with ischaemic heart failure
    Riemer H J A Slart
    Nucl Med Commun 27:317-20. 2006
  34. ncbi Better yield of (18)fluorodeoxyglucose-positron emission tomography in patients with metastatic differentiated thyroid carcinoma during thyrotropin stimulation
    Karin M van Tol
    Department of Endocrinology, University Hospital Groningen, The Netherlands
    Thyroid 12:381-7. 2002
    ..To detect metastatic or recurrent differentiated thyroid carcinoma FDG-PET should be performed during hypothyroidism, leading to TSH stimulation...