Research Topics
Species | Juan P IanowskiSummaryAffiliation: McMaster University Country: Canada Publications
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Publications
Intracellular ion activities in Malpighian tubule cells of Rhodnius prolixus: evaluation of Na+-K+-2Cl- cotransport across the basolateral membraneJuan P Ianowski
Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1
J Exp Biol 205:1645-55. 2002..Bumetanide reduced the fluxes of both Na+ and K+. Taken together, the results support the involvement of a basolateral Na+-K+-2Cl- cotransporter in serotonin-stimulated fluid secretion by Rhodnius prolixus Malpighian tubules...
Na+ competes with K+ in bumetanide-sensitive transport by Malpighian tubules of Rhodnius prolixusJuan P Ianowski
Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada, L8S 4K1
J Exp Biol 207:3707-16. 2004..We propose that the competition between Na+ and K+ for transport by the bumetanide-sensitive transporter is part of an autonomous mechanism by which Malpighian tubules regulate haemolymph K+ concentration...
Basolateral ion transport mechanisms during fluid secretion by Drosophila Malpighian tubules: Na+ recycling, Na+:K+:2Cl- cotransport and Cl- conductanceJuan P Ianowski
Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada, L8S 4K1
J Exp Biol 207:2599-609. 2004....
The antidiuretic neurohormone RhoprCAPA-2 downregulates fluid transport across the anterior midgut in the blood-feeding insect Rhodnius prolixusJuan P Ianowski
Department of Biology, University of Toronto Mississauga, Mississauga, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 298:R548-57. 2010....
Secretion of water and ions by malpighian tubules of larval mosquitoes: effects of diuretic factors, second messengers, and salinityAndrew Donini
Department of Biology, McMaster University, Life Sciences Building, Hamilton, Ontario, Canada
Physiol Biochem Zool 79:645-55. 2006..Results indicate that changes in rearing medium salinity affect the nature and extent of stimulation of fluid and ion secretion by secretagogues...
Electrochemical gradients for Na+, K+, Cl- and H+ across the apical membrane in Malpighian (renal) tubule cells of Rhodnius prolixusJuan P Ianowski
Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
J Exp Biol 209:1964-75. 2006..The data are consistent with a role for a basolateral Na+/H+ exchanger in intracellular pH regulation during fluid secretion...
Inorganic and organic anion transport by insect renal epitheliaMichael J O'Donnell
Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1
Biochim Biophys Acta 1618:194-206. 2003..Insect renal epithelia are also important in excretion of potentially toxic organic anions, and the transporters involved may play a role in resistance to insecticides of natural or anthropogenic origin...
Amino acids modulate ion transport and fluid secretion by insect Malpighian tubulesMatthew H Hazel
Dept of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4KI, Canada
J Exp Biol 206:79-91. 2003..We suggest that the amino acids probably function as compatible intracellular osmolytes that are necessary for sustained secretion at high rates by the Malpighian tubules...
Biological activity of diuretic factors on the anterior midgut of the blood-feeding bug, Rhodnius prolixusVictoria Te Brugge
Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario, Canada
Gen Comp Endocrinol 162:105-12. 2009..All of the factors studied increase the frequency of contractions of the anterior midgut...
Effects of cortisol and prolactin on Na+ and Cl- transport in cultured branchial epithelia from FW rainbow troutBingsheng Zhou
Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada
Am J Physiol Regul Integr Comp Physiol 285:R1305-16. 2003..Overall, prolactin alone did not appear to promote FW adaptation but exhibited synergism with cortisol. These results provide further support for the cultured DSI epithelium as an in vitro model for ion transport in FW fish...
Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout miceJuan P Ianowski
Department of Physiology, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada H3G 1Y6
J Physiol 580:301-14. 2007..These results clarify the mechanisms of murine submucosal gland secretion and reveal a novel defect in local regulation of glands lacking CFTR which may also compromise airway defence in CF patients...
Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosisJae Young Choi
Cystic Fibrosis Research Laboratory, Stanford University, Stanford, California, USA
J Clin Invest 117:3118-27. 2007..Loss of "housekeeping" gland mucus secretion in CF, in combination with demonstrated defects in surface epithelia, may play a role in the vulnerability of CF airways to bacterial infections...
