G H Guyatt
Affiliation: McMaster University
- Akl E, Kahale L, Agoritsas T, Brignardello Petersen R, Busse J, Carrasco Labra A, et al. Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches. Syst Rev. 2015;4:98 pubmed publisher..Although these approaches require further testing, they may guide review authors in addressing missing participant data. ..
- Yonemoto N, Tanaka S, Furukawa T, Kato T, Mantani A, Ogawa Y, et al. Strategic use of new generation antidepressants for depression: SUN(^_^) D protocol update and statistical analysis plan. Trials. 2015;16:459 pubmed publisher..This paper presents the updated protocol and the detailed statistical analysis plan for the SUN(^_^)D trial in order to avoid reporting bias and data-driven results. ClinicalTrials.gov: NCT01109693 (registered on 21 April 2010). ..
- Guyatt G, Oxman A, Montori V, Vist G, Kunz R, Brozek J, et al. GRADE guidelines: 5. Rating the quality of evidence--publication bias. J Clin Epidemiol. 2011;64:1277-82 pubmed publisher..Publication bias is likely frequent, and caution in the face of early results, particularly with small sample size and number of events, is warranted. ..
- Guyatt G, Oxman A, Kunz R, Brozek J, Alonso Coello P, Rind D, et al. GRADE guidelines 6. Rating the quality of evidence--imprecision. J Clin Epidemiol. 2011;64:1283-93 pubmed publisher..If the 95% CI includes appreciable benefit or harm (we suggest an RR of under 0.75 or over 1.25 as a rough guide) rating down for imprecision may be appropriate even if OIS criteria are met. ..
- Florez I, Al Khalifah R, Sierra J, Granados C, Yepes NuÃ±ez J, Cuello García C, et al. The effectiveness and safety of treatments used for acute diarrhea and acute gastroenteritis in children: protocol for a systematic review and network meta-analysis. Syst Rev. 2016;5:14 pubmed publisher..The results will help to reduce the uncertainty of the effectiveness of the interventions, find knowledge gaps, and/or encourage further research for other therapeutic options. PROSPERO registration number: CRD42015023778. ..
- Carles M, Brosa M, Souto J, Garcia Alamino J, Guyatt G, Alonso Coello P. Cost-effectiveness analysis of dabigatran and anticoagulation monitoring strategies of vitamin K antagonist. BMC Health Serv Res. 2015;15:289 pubmed publisher..Our analyses contrast with the available cost analysis of dabigatran and usual care of anticoagulated patients. ..
- Guyatt G, Oxman A, Akl E, Kunz R, Vist G, Brozek J, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011;64:383-94 pubmed publisher..Subsequent articles in this series will address GRADE's approach to formulating questions, assessing quality of evidence, and developing recommendations. ..
- Guyatt G, Oxman A, Schunemann H, Tugwell P, Knottnerus A. GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol. 2011;64:380-2 pubmed publisher..gradeworkinggroup.org/), attests to the importance of this work. This article introduces a 20-part series providing guidance for the use of GRADE methodology that will appear in the Journal of Clinical Epidemiology. ..
- Morgan R, Thayer K, Bero L, Bruce N, Falck Ytter Y, Ghersi D, et al. GRADE: Assessing the quality of evidence in environmental and occupational health. Environ Int. 2016;92-93:611-6 pubmed publisher..The objectives of this article are to provide an overview of GRADE, discuss GRADE's applicability to environmental health, and identify priority areas for method assessment and development. ..
- Sekercioglu N, Busse J, Mustafa R, Guyatt G, Thabane L. Cinacalcet versus standard treatment for chronic kidney disease: a protocol for a systematic review and meta-analysis. Syst Rev. 2016;5:2 pubmed publisher..The results of this systematic review will help guide management of this patient population, and identify targets for future research. PROSPERO CRD42015020318 http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015020318. ..
- Guyatt G, Oxman A, Vist G, Kunz R, Brozek J, Alonso Coello P, et al. GRADE guidelines: 4. Rating the quality of evidence--study limitations (risk of bias). J Clin Epidemiol. 2011;64:407-15 pubmed publisher..Rather, for any individual outcome, when there are some studies with a high risk, and some with a low risk of bias, they should consider including only the studies with a lower risk of bias. ..
- Yepes Nuñez J, Zhang Y, Xie F, Alonso Coello P, Selva A, Schunemann H, et al. Forty-two systematic reviews generated 23 items for assessing the risk of bias in values and preferences' studies. J Clin Epidemiol. 2017;85:21-31 pubmed publisher..The items and domains identified provide insight into issues of RoB in patients' values and preference studies and establish the basis for an instrument to assess RoB in such studies. ..
- Zhang Y, Alyass A, Vanniyasingam T, Sadeghirad B, Florez I, Pichika S, et al. A systematic survey of the methods literature on the reporting quality and optimal methods of handling participants with missing outcome data for continuous outcomes in randomized controlled trials. J Clin Epidemiol. 2017;88:67-80 pubmed publisher..Simulation studies addressing methods to deal with MPD suffered from serious limitations. The mixed model approach was superior to other methods in terms of overall performance and bias. LOCF performed worst. ..
- Guyatt G, Thorlund K, Oxman A, Walter S, Patrick D, Furukawa T, et al. GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes. J Clin Epidemiol. 2013;66:173-83 pubmed publisher..We outline the merits and limitations of each alternative and provide guidance for meta-analysts and guideline developers. ..
- Guyatt G, Oxman A, Sultan S, Glasziou P, Akl E, Alonso Coello P, et al. GRADE guidelines: 9. Rating up the quality of evidence. J Clin Epidemiol. 2011;64:1311-6 pubmed publisher..Other considerations include the rapidity of the response, the underlying trajectory of the condition, and indirect evidence. ..
- Mbuagbaw L, Rochwerg B, Jaeschke R, Heels Andsell D, Alhazzani W, Thabane L, et al. Approaches to interpreting and choosing the best treatments in network meta-analyses. Syst Rev. 2017;6:79 pubmed publisher..We present ranking approaches' merits and limitations and provide an example of how to apply the results of a NMA to clinical practice. ..
- Zhang Y, Florez I, Colunga Lozano L, Aloweni F, Kennedy S, Li A, et al. A systematic survey on reporting and methods for handling missing participant data for continuous outcomes in randomized controlled trials. J Clin Epidemiol. 2017;88:57-66 pubmed publisher..Most RCTs failed to use optimal analytic methods, and very few conducted sensitivity analyses addressing the possible impact of MPD or commented on how MPD might influence risk of bias. ..