R Goeree

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. doi request reprint Total or partial knee replacement? Cost-utility analysis in patients with knee osteoarthritis based on a 2-year observational study
    Feng Xie
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, ON, Canada
    Eur J Health Econ 11:27-34. 2010
  2. doi request reprint Introduction to health economics and decision-making: Is economics relevant for the frontline clinician?
    Ron Goeree
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada Electronic address
    Best Pract Res Clin Gastroenterol 27:831-44. 2013
  3. pmc Simulating an emergency department: the importance of modeling the interactions between physicians and delegates in a discrete event simulation
    Morgan E Lim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    BMC Med Inform Decis Mak 13:59. 2013
  4. doi request reprint Economic appraisal of a community-wide cardiovascular health awareness program
    Ron Goeree
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Value Health 16:39-45. 2013
  5. pmc A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive hyperbaric oxygen therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients wi
    Daria O'Reilly
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Trials 12:69. 2011
  6. pmc Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies
    P M Ciaschini
    Algoma District Medical Group, Sault Ste Marie, Canada
    Trials 9:62. 2008
  7. pmc A review of health utilities across conditions common in paediatric and adult populations
    Jean Eric Tarride
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Ontario, Canada
    Health Qual Life Outcomes 8:12. 2010
  8. pmc Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up
    Feng Xie
    Programs for Assessment of Technology in Health, St, Joseph s Healthcare Hamilton, Hamilton, L8P 1H1, Canada
    Health Qual Life Outcomes 8:87. 2010
  9. pmc Cost-utility analysis of infliximab and adalimumab for refractory ulcerative colitis
    Feng Xie
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Cost Eff Resour Alloc 7:20. 2009
  10. pmc Cost-utility of Intravenous Immunoglobulin (IVIG) compared with corticosteroids for the treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Canada
    Gord Blackhouse
    PATH Research Institute, McMaster University, Hamilton, Ontario, Canada
    Cost Eff Resour Alloc 8:14. 2010

Detail Information

Publications102 found, 100 shown here

  1. doi request reprint Total or partial knee replacement? Cost-utility analysis in patients with knee osteoarthritis based on a 2-year observational study
    Feng Xie
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, ON, Canada
    Eur J Health Econ 11:27-34. 2010
    ..Based on the 2-year data, TKR gained more QALYs at higher costs compared to UKA. A long-term prospective study is necessary to determine cost-effectiveness of TKR and UKA...
  2. doi request reprint Introduction to health economics and decision-making: Is economics relevant for the frontline clinician?
    Ron Goeree
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada Electronic address
    Best Pract Res Clin Gastroenterol 27:831-44. 2013
    ..Particularly, the content of the paper will facilitate clinicians' understanding of the link between economics and their medical practice, and how clinical decision-making reflects on health care resource allocation...
  3. pmc Simulating an emergency department: the importance of modeling the interactions between physicians and delegates in a discrete event simulation
    Morgan E Lim
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    BMC Med Inform Decis Mak 13:59. 2013
    ....
  4. doi request reprint Economic appraisal of a community-wide cardiovascular health awareness program
    Ron Goeree
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Value Health 16:39-45. 2013
    ..Although studies have shown that modifying CVD risk factors at the patient level improves patient prognosis, the effect of community-wide interventions at the population level has been uncertain...
  5. pmc A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive hyperbaric oxygen therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients wi
    Daria O'Reilly
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Trials 12:69. 2011
    ....
  6. pmc Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies
    P M Ciaschini
    Algoma District Medical Group, Sault Ste Marie, Canada
    Trials 9:62. 2008
    ..TRIAL REGISTRATION: This trial has been registered with clinicaltrials.gov (ID: NCT00465387)...
  7. pmc A review of health utilities across conditions common in paediatric and adult populations
    Jean Eric Tarride
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Ontario, Canada
    Health Qual Life Outcomes 8:12. 2010
    ....
  8. pmc Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up
    Feng Xie
    Programs for Assessment of Technology in Health, St, Joseph s Healthcare Hamilton, Hamilton, L8P 1H1, Canada
    Health Qual Life Outcomes 8:87. 2010
    ..To quantify the improvement in health outcomes in patients after total knee replacement (TKR)...
  9. pmc Cost-utility analysis of infliximab and adalimumab for refractory ulcerative colitis
    Feng Xie
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Cost Eff Resour Alloc 7:20. 2009
    ..Future research could be aimed at the long-term clinical benefits of these drugs, especially adalimumab for patients intolerant or unresponsive to infliximab treatment...
  10. pmc Cost-utility of Intravenous Immunoglobulin (IVIG) compared with corticosteroids for the treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Canada
    Gord Blackhouse
    PATH Research Institute, McMaster University, Hamilton, Ontario, Canada
    Cost Eff Resour Alloc 8:14. 2010
    ..The objective of the paper is to evaluate, from a Canadian perspective, the cost-effectiveness of IVIG compared to corticosteroid treatment of CIDP...
  11. pmc The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women
    Robert B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 12:209. 2011
    ..The purpose was to estimate the relative efficacy of reduction of fractures in post-menopausal women, and to assess robustness of the results...
  12. pmc The importance of adjusting for potential confounders in Bayesian hierarchical models synthesising evidence from randomised and non-randomised studies: an application comparing treatments for abdominal aortic aneurysms
    C Elizabeth McCarron
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Med Res Methodol 10:64. 2010
    ..The objective of this study was to extend a published Bayesian hierarchical model to adjust for bias due to confounding in synthesising evidence from studies with different designs...
  13. pmc Community based intervention to optimize osteoporosis management: randomized controlled trial
    Patricia M Ciaschini
    Algoma District Medical Group, Sault Ste Marie, Canada
    BMC Geriatr 10:60. 2010
    ..This pragmatic randomised study was done to evaluate the impact of a multifaceted community-based care program aimed at optimizing evidence-based management in patients at risk for osteoporosis and fractures...
  14. pmc Prehospital evaluation and economic analysis of different coronary syndrome treatment strategies--PREDICT--rationale, development and implementation
    Laurie J Morrison
    Rescue, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    BMC Emerg Med 11:4. 2011
    ..The main objective is to compare prehospital care strategies for time to treatment and survival outcomes as well as cost effectiveness...
  15. ncbi request reprint The economic burden of schizophrenia in Canada in 2004
    R Goeree
    Program for Assessment of Technology in Health, St Joseph s Healthcare, McMaster University, Hamilton, Ontario, Canada
    Curr Med Res Opin 21:2017-28. 2005
    ..To estimate the financial burden of schizophrenia in Canada in 2004...
  16. doi request reprint Health technology assessment and primary data collection for reducing uncertainty in decision making
    Ron Goeree
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    J Am Coll Radiol 6:332-42. 2009
    ..Most tools used to assist with evidence-based decision making focus on clinical outcomes...
  17. doi request reprint Economic evaluation of drug-eluting stents compared to bare metal stents using a large prospective study in Ontario
    Ron Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Int J Technol Assess Health Care 25:196-207. 2009
    ....
  18. ncbi request reprint Cost-effectiveness of alternative treatments for women with osteoporosis in Canada
    Ron Goeree
    Program for Assessment of Technology in Health PATH, McMaster University, Ontario, Canada
    Curr Med Res Opin 22:1425-36. 2006
    ..During the years following menopause, estrogen levels decline leading to accelerated bone loss and an increased risk of osteoporosis and osteoporosis-related fractures...
  19. ncbi request reprint Building bridges between academic research and policy formulation: the PRUFE framework - an integral part of Ontario's evidence-based HTPA process
    Ron Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Pharmacoeconomics 24:1143-56. 2006
    ..MAS/OHTAC has undertaken evidence-based analyses for >50 new technologies. The PRUFE framework has been successful for reducing uncertainty and controlling healthcare expenditures while providing access and improving patient outcomes...
  20. doi request reprint General population versus disease-specific event rate and cost estimates: potential bias for economic appraisals
    Ron Goeree
    Programs for the Assessment of Technology in Health Research Institute, 25 Main St W, Suite 2000, Hamilton, ON L8P 1H1, Canada
    Expert Rev Pharmacoecon Outcomes Res 10:379-84. 2010
    ....
  21. ncbi request reprint Cost-effectiveness modeling in rheumatology: toward principles of good practice
    Ron Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 1G6, Canada
    J Rheumatol Suppl 68:21-2. 2003
  22. ncbi request reprint Transferability of economic evaluations: approaches and factors to consider when using results from one geographic area for another
    Ron Goeree
    St Joseph s Hospital, Hamilton, ON, Canada
    Curr Med Res Opin 23:671-82. 2007
    ..However, inappropriate transferability of economic data can provide misleading results and lead to an inefficient use of scarce health care resources...
  23. doi request reprint Cost-utility of laparoscopic Nissen fundoplication versus proton pump inhibitors for chronic and controlled gastroesophageal reflux disease: a 3-year prospective randomized controlled trial and economic evaluation
    Ron Goeree
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare, Hamilton, ON, Canada
    Value Health 14:263-73. 2011
    ..Larger RCTs have been relatively short in duration, and have reported mixed results regarding symptom control and effect on quality of life (QOL). Economic evaluations have reported conflicting results...
  24. ncbi request reprint Cost-effectiveness and cost-utility of long-term management strategies for heartburn
    Ron Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 1G6, Canada
    Value Health 5:312-28. 2002
    ..To compare the expected costs and outcomes of seven alternative long-term primary care strategies for the management of patients with moderate-to-severe heartburn over a 1-year period...
  25. ncbi request reprint The economic burden of schizophrenia in Canada
    R Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario
    Can J Psychiatry 44:464-72. 1999
    ..To estimate the financial burden of schizophrenia in Canada in 1996...
  26. pmc The burden of illness of osteoporosis in Canada
    J E Tarride
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, 25 Main Street West, Suite 2000, Hamilton, ON, L8P 1H1, Canada
    Osteoporos Int 23:2591-600. 2012
    ..3 billion in Canada or 1.3% of Canada's healthcare expenditures. Prevention of fractures in high-risk individuals is key to decrease the financial burden of osteoporosis...
  27. doi request reprint Estimating the excess costs for patients with incident fractures, prevalent fractures, and nonfracture osteoporosis
    R B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, ON, Canada
    Osteoporos Int 24:581-93. 2013
    ..Prevalent fractures also have significant excess costs that are similar in relative magnitude to asthma/chronic obstructive pulmonary disease...
  28. ncbi request reprint Cost effectiveness of alternative Helicobacter pylori eradication strategies in the management of duodenal ulcer
    B O'BRIEN
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario
    Can J Gastroenterol 11:323-31. 1997
    ..A limitation of the analysis is that it did not incorporate issues of compliance and metronidazole resistance; however, the former concern may be less of an issue as H pylori regimens become simpler and shorter in duration...
  29. ncbi request reprint Systematic implementation of an advance directive program in nursing homes: a randomized controlled trial
    D W Molloy
    Department of Medicine, McMaster University, Ontario, Canada
    JAMA 283:1437-44. 2000
    ..Although advance directives are commonly used in the community, little is known about the effects of their systematic implementation...
  30. ncbi request reprint Economic evaluation of long-term management strategies for erosive oesophagitis
    R Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Pharmacoeconomics 16:679-97. 1999
    ..To compare the expected costs and outcomes of alternative strategies for the management of patients with erosive oesophagitis...
  31. ncbi request reprint The valuation of productivity costs due to premature mortality: a comparison of the human-capital and friction-cost methods for schizophrenia
    R Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario
    Can J Psychiatry 44:455-63. 1999
    ..To compare productivity-cost estimates for schizophrenia-related premature mortality in Canada in 1996 using the human-capital (HC) approach and friction-cost (FC) method...
  32. ncbi request reprint Economic implications of hip fracture: health service use, institutional care and cost in Canada
    M E Wiktorowicz
    Departments of Epidemiology and Biostatistics and Political Science, University of Western Ontario, London, Ontario, Canada
    Osteoporos Int 12:271-8. 2001
    ..Annual economic implications of hip fracture in Canada are $650 million and are expected to rise to $2.4 billion by 2041...
  33. doi request reprint Estimation of the lifetime risk of hip fracture for women and men in Canada
    R B Hopkins
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Science, McMaster University, Hamilton, ON, Canada
    Osteoporos Int 23:921-7. 2012
    ..1% and 4.6%, respectively, and 8.9% and 6.7% after incorporating declining rates of hip fracture and increases in longevity...
  34. ncbi request reprint Cost-Effectiveness of tolterodine for patients with urge incontinence who discontinue initial therapy with oxybutynin: a Canadian perspective
    B J O'Brien
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Clin Ther 23:2038-49. 2001
    ..Tolterodine is a novel muscarinic receptor antagonist for the treatment of overactive bladder...
  35. ncbi request reprint Will the use of low-molecular-weight heparin (enoxaparin) in patients with acute coronary syndrome save costs in Canada?
    B J O'Brien
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Canada
    Am Heart J 139:423-9. 2000
    ..Given the higher acquisition cost of enoxaparin relative to unfractionated heparin, we assessed whether the reduced use of revascularization procedures and related care makes enoxaparin a cost-saving therapy in Canada...
  36. doi request reprint Health technology assessment: a review of international activity and examples of approaches with computed tomographic colonography
    Don Husereau
    Canadian Agency for Drugs and Technologies in Health, Ottawa, Ontario, Canada
    J Am Coll Radiol 6:343-52. 2009
    ....
  37. ncbi request reprint Establishing a comprehensive continuum from an evidentiary base to policy development for health technologies: the Ontario experience
    Leslie Levin
    Ministry of Health and Long Term Care and University of Toronto, Ontario, Canada
    Int J Technol Assess Health Care 23:299-309. 2007
    ....
  38. doi request reprint Cost-effectiveness of denosumab in the treatment of postmenopausal osteoporosis in Canada
    D Chau
    Amgen Canada Inc, Mississauga, Ontario, Canada
    J Med Econ 15:3-14. 2012
    ..This study estimated cost-effectiveness of denosumab vs usual care from the perspective of the Ontario public payer...
  39. ncbi request reprint Cost effectiveness in Canada of a multidrug prepackaged regimen (Hp-PAC)+ for Helicobacter pylori eradication
    K Agro
    Centre for Evaluation of Medicines, St Joseph's Hospital, Hamilton, Ontario, Canada
    Pharmacoeconomics 19:831-43. 2001
    ..More data on the clinical and statistical differences in H. pylori eradication with Hp-PAC and PPI-CM would be useful. This analysis does not in clude the possible advantage of Hp-PAC in terms of compliance and antibacterial resistance...
  40. ncbi request reprint A Canadian physician survey of dyspepsia management
    N Chiba
    Surrey GI Clinic, Guelph, Ontario
    Can J Gastroenterol 12:83-90. 1998
    ..To determine the management of patients with new onset dyspepsia by Canadian family physicians...
  41. doi request reprint A cost-effectiveness model comparing endovascular repair to open surgical repair of abdominal aortic aneurysms in Canada
    Gord Blackhouse
    Program for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Ontario, Canada
    Value Health 12:245-52. 2009
    ..EVAR is less invasive than OR, and therefore may have less surgical risk than OR. However, the graft used for EVAR is much more expensive then the graft used for OR...
  42. doi request reprint Economic evaluations conducted by Canadian health technology assessment agencies: where do we stand?
    Jean Eric Tarride
    Department of Clinical Epidemiology and Biostatistics, McMaster University St Joseph s Healthcare Hamilton, 25 Main Street West, Hamilton, Ontario, Canada
    Int J Technol Assess Health Care 24:437-44. 2008
    ..To examine the production of Health Technology Assessments (HTAs) with economic evaluations (EEs) conducted by Canadian HTA agencies...
  43. pmc Effects of study design and trends for EVAR versus OSR
    Robert Hopkins
    Program for the Assessment of Technology in Health PATH Research Institute, Department of Clinical Epidemiology and Biostatistics, London Health Sciences Center, London, Ontario, Canada
    Vasc Health Risk Manag 4:1011-22. 2008
    ..Finally, we investigate trends over time in EVAR versus OSR outcomes...
  44. ncbi request reprint Effect of a clinical pathway to reduce hospitalizations in nursing home residents with pneumonia: a randomized controlled trial
    Mark Loeb
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    JAMA 295:2503-10. 2006
    ..Nursing home residents with pneumonia are frequently hospitalized. Such transfers may be associated with multiple hazards of hospitalization as well as economic costs...
  45. doi request reprint In search of the evidentiary foundation of published Canadian economic evaluations (2001-06)
    Jean Eric Tarride
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Programs for Assessment of Technology in Health PATH Research Institute, 25 Main Street West, Suite 2000, Hamilton, Ontario L8P 1H1, Canada
    Int J Technol Assess Health Care 25:214-21. 2009
    ....
  46. doi request reprint Systematic review and meta-analysis of transurethral resection of the prostate versus minimally invasive procedures for the treatment of benign prostatic obstruction
    Natasha Burke
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Urology 75:1015-22. 2010
    ..However, long-term follow-up and stronger methodological quality of the evidence is required to assess the long-term durability of the technologies...
  47. doi request reprint Approaches for economic evaluations of health care technologies
    Jean Eric Tarride
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    J Am Coll Radiol 6:307-16. 2009
    ..This review improves upon the previous educational papers published in radiologic journals, as it covers recent methodologic advances regarding the treatment of uncertainty...
  48. doi request reprint Illustrating economic evaluation of diagnostic technologies: comparing Helicobacter pylori screening strategies in prevention of gastric cancer in Canada
    Feng Xie
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    J Am Coll Radiol 6:317-23. 2009
    ..The aim of this paper is to present an economic evaluation of diagnostic technologies using Helicobacter pylori screening strategies for the prevention of gastric cancer as an illustration...
  49. doi request reprint Conditionally funded field evaluations and practical trial design within a health technology assessment framework
    James M Bowen
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    J Am Coll Radiol 6:324-31. 2009
    ....
  50. pmc Cost analysis of multiplex PCR testing for diagnosing respiratory virus infections
    James B Mahony
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    J Clin Microbiol 47:2812-7. 2009
    ..We conclude that the use of the xTAG RVP test is the least costly strategy for the diagnosis of respiratory virus infections in children and would generate a significant savings for hospitals...
  51. doi request reprint Results of a model analysis to estimate cost utility and value of information for intravenous immunoglobulin in Canadian adults with chronic immune thrombocytopenic purpura
    Feng Xie
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Clin Ther 31:1082-91; discussion 1066-8. 2009
    ..The aim of this work was to estimate the cost-effectiveness of intravenous immunoglobulin (IVIg) compared with oral prednisone as a treatment for Canadian adults with persistent chronic immune thrombocytopenic purpura (ITP)...
  52. doi request reprint Health technology assessment from a Canadian device industry perspective
    Ilia L Ferrusi
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    J Am Coll Radiol 6:353-9. 2009
    ....
  53. pmc A review of the cost of cardiovascular disease
    Jean Eric Tarride
    St Joseph s Healthcare Hamilton and McMaster University, Hamilton, Canada
    Can J Cardiol 25:e195-202. 2009
    ..While considerable variation was observed among studies, all studies indicated that the costs of treating CVD-related conditions are significant, outlining a convincing case for CVD prevention programs...
  54. doi request reprint Impact of the 1997 Canadian guidelines on the conduct of Canadian-based economic evaluations in the published literature
    Morgan E Lim
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, ON, Canada
    Value Health 13:328-34. 2010
    ..To assess the impact of the 1997 Canadian guidelines on the methods and presentation of economic evaluations conducted from a Canadian perspective in the published literature...
  55. ncbi request reprint Universal or targeted screening for fetal alcohol exposure: a cost-effectiveness analysis
    Robert B Hopkins
    Program for Assessment of Technology in Health, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, 25 Main Street West, Suite 2000, Hamilton, Ontario, L8P 2A1, Canada
    J Stud Alcohol Drugs 69:510-9. 2008
    ..In this article, we compared the costs of testing meconium for alcohol exposure in newborns with the lifetime benefits of early detection and intervention...
  56. ncbi request reprint A randomized controlled trial of laparoscopic nissen fundoplication versus proton pump inhibitors for treatment of patients with chronic gastroesophageal reflux disease: One-year follow-up
    Mehran Anvari
    Centre for Minimal Access Surgery, Department of Surgery, St Joseph s Healthcare, 50 Charlton Ave E, Hamilton, ON, L8N 4A6 Canada
    Surg Innov 13:238-49. 2006
    ..Patients controlled on long-term proton pump inhibitor therapy for chronic gastroesophageal reflux disease are excellent surgical candidates and should experience improved symptom control after surgery at 1 year...
  57. ncbi request reprint Oseltamivir for treatment of influenza in healthy adults: pooled trial evidence and cost-effectiveness model for Canada
    Bernie J O'Brien
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Value Health 6:116-25. 2003
    ..Oseltamivir (Tamiflu) is a neuraminidase inhibitor-a new class of antiviral treatment for influenza where efficacy and safety has been established but cost-effectiveness is unknown...
  58. doi request reprint Health technology assessment for radiologists: basic principles and evaluation framework
    Morgan E Lim
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    J Am Coll Radiol 6:299-306. 2009
    ..Third, the authors provide a real-world example of an HTA in the field of diagnostics. Last, they describe the challenges and barriers faced in HTA...
  59. doi request reprint Validation of Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients scheduled for total knee replacement
    Feng Xie
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    Qual Life Res 17:595-601. 2008
    ..Our aim was to cross-culturally validate Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients with knee osteoarthritis (OA) scheduled for total knee replacement in Singapore...
  60. doi request reprint Cost-effectiveness analysis of Helicobacter pylori screening in prevention of gastric cancer in Chinese
    Feng Xie
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Int J Technol Assess Health Care 24:87-95. 2008
    ..The aim of this study was to evaluate the costs and effectiveness associated with no screening, Helicobacter pylori serology screening, and the 13C-urea breath test (UBT) for gastric cancer in the Chinese population...
  61. doi request reprint Handling uncertainty in economic evaluations of patient level data: a review of the use of Bayesian methods to inform health technology assessments
    C Elizabeth McCarron
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Programs for Assessment of Technology in Health PATH Research Institute, Ontario, Canada
    Int J Technol Assess Health Care 25:546-54. 2009
    ..The results serve both as a reference and as a means by which to examine the appropriate application of Bayesian methods to inform decision making...
  62. doi request reprint Cost-effectiveness of reducing wait times for cataract surgery in Ontario
    Robert B Hopkins
    Department of Clinical Epidemiology and Biostatistics, McMaster University, and the Programs for Assessment of Technology in Health Research Institute, St Joseph s Hospital, Hamilton, ON, Canada
    Can J Ophthalmol 43:213-7. 2008
    ..The objective of the study was to use queuing models to determine the cost-effectiveness of reducing, to target levels, wait times for cataract surgery at the provincial level within 1 to 10 years by increasing treatment volumes...
  63. doi request reprint Patient outcomes after anti TNF-alpha drugs for Crohn's disease
    Nazila Assasi
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare, Hamilton, 25 Main Street West, Suite 2000 ON, Canada
    Expert Rev Pharmacoecon Outcomes Res 10:163-75. 2010
    ..The review further considers the evidence for the harms and benefits associated with switching from one anti-TNF-alpha agent to another and strategies to optimize the timing of therapy...
  64. doi request reprint Analysis of health utility data when some subjects attain the upper bound of 1: are Tobit and CLAD models appropriate?
    Eleanor M Pullenayegum
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    Value Health 13:487-94. 2010
    ..We aimed to examine whether the Tobit and CLAD models yielded acceptable results when this censoring assumption was not appropriate...
  65. doi request reprint A review of methods used in long-term cost-effectiveness models of diabetes mellitus treatment
    Jean Eric Tarride
    Programs for Assessment of Technology in Health Research Institute, St Joseph s Healthcare Hamilton, 25 Main Street West, Hamilton, Ontario, Canada
    Pharmacoeconomics 28:255-77. 2010
    ..Future research should continue to compare economic models for diabetes treatment in terms of clinical outcomes, costs and QALYs when applicable...
  66. ncbi request reprint A comparison between integrating clinical practice setting and randomized controlled trial setting into economic evaluation models of therapeutics
    Pendar Farahani
    Centre for Evaluation of Medicines, St Joseph s Healthcare, McMaster University, Hamilton, ON, Canada
    J Eval Clin Pract 12:463-70. 2006
    ....
  67. ncbi request reprint Hospital selection for unit cost estimates in multicentre economic evaluations. Does the choice of hospitals make a difference?
    R Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Pharmacoeconomics 15:561-72. 1999
    ....
  68. ncbi request reprint Cost-effectiveness of the implantable cardioverter-defibrillator: results from the Canadian Implantable Defibrillator Study (CIDS)
    S J Connolly
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Circulation 103:1416-21. 2001
    ..Further research is warranted to identify the indications and patient subgroups for whom ICDs are a cost-effective use of resources...
  69. doi request reprint Implementing a standardized community-based cardiovascular risk assessment program in 20 Ontario communities
    Megan Carter
    Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
    Health Promot Int 24:325-33. 2009
    ..Monitoring delivery of a multi-community cardiovascular risk assessment program yielded key factors in program success to inform development of a sustainable and transferable model...
  70. pmc A randomized controlled trial of a pharmacist consultation program for family physicians and their elderly patients
    John Sellors
    Department of Family Medicine, McMaster University, Hamilton, Ont
    CMAJ 169:17-22. 2003
    ..We examined whether an intervention by a specially trained pharmacist could reduce the number of daily medication units taken by elderly patients, as well as costs and health care use...
  71. doi request reprint Cost-effectiveness analysis of elective endovascular repair compared with open surgical repair of abdominal aortic aneurysms for patients at a high surgical risk: A 1-year patient-level analysis conducted in Ontario, Canada
    Jean Eric Tarride
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare, Hamilton, Ontario, Canada
    J Vasc Surg 48:779-87. 2008
    ..The objective of this study was to estimate the cost-effectiveness and cost-utility of elective endovascular aneurysm repair (EVAR) compared with open surgical repair (OSR) in patients at a high risk of surgical complications...
  72. ncbi request reprint Cost-effectiveness of screening swab or urine specimens for Chlamydia trachomatis from young Canadian women in Ontario
    R Goeree
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Sex Transm Dis 28:701-9. 2001
    ..Expanding the screening program to include all women ages 15 to 24 years is considerably more expensive and only moderately more effective than screening only high-risk women...
  73. ncbi request reprint A randomized trial of strategies for assessing eligibility for long-term domiciliary oxygen therapy
    Gordon H Guyatt
    Department of Medicine, McMaster University, Hamilton, Canada
    Am J Respir Crit Care Med 172:573-80. 2005
    ..Restricting oxygen administration to those who benefit is desirable...
  74. ncbi request reprint Basics of health technology assessment
    Daria O'Reilly
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Methods Mol Biol 473:263-83. 2009
    ..Whether HTA is beneficial (supporting timely access to needed technologies) or detrimental depends on three critical issues: when the assessment is performed, how it is performed, and how the findings are used...
  75. ncbi request reprint Cost-effectiveness of physiologic pacing: results of the Canadian Health Economic Assessment of Physiologic Pacing
    Bernie J O'Brien
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Heart Rhythm 2:270-5. 2005
    ..The purpose of this study was to determine the cost-effectiveness of physiologic pacemakers...
  76. ncbi request reprint Patient views on reminder letters for influenza vaccinations in an older primary care patient population: a mixed methods study
    Kelly K Anderson
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON
    Can J Public Health 99:133-6. 2008
    ..To explore the perspectives of older adults on the acceptability of reminder letters for influenza vaccinations...
  77. ncbi request reprint Economic evaluation of rivastigmine in patients with Parkinson's disease dementia
    Andrew R Willan
    SickKids Research Institute and Department of Public Health Sciences, Programme in Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Pharmacoeconomics 24:93-106. 2006
    ..Patient-level healthcare utilisation data were also collected, and this report is the economic evaluation based on these data...
  78. ncbi request reprint Costs associated with erythropoiesis-stimulating agent administration to hemodialysis patients
    David N Churchill
    Division of Nephrology, Faculty of Health Sciences, McMaster University, Hamilton, Ont, Canada
    Nephron Clin Pract 106:c193-8. 2007
    ..Cost analyses usually focus on drug acquisition costs. Other costs associated with anemia therapy include resources for anemia monitoring as well as preparation and administration of an erythropoiesis-stimulating agent...
  79. pmc Photodynamic therapy for Barrett's esophagus with high-grade dysplasia: a cost-effectiveness analysis
    Dan Comay
    Department of Medicine, Divison of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 21:217-22. 2007
    ..To assess the cost-effectiveness of photodynamic therapy (PDT) and esophagectomy (ESO) relative to surveillance (SURV) for patients with Barrett's esophagus (BE) and high-grade dysplasia (HGD)...
  80. doi request reprint Safety and effectiveness of drug-eluting and bare-metal stents for patients with off- and on-label indications
    Dennis T Ko
    Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Cardiol 53:1773-82. 2009
    ..Our main objective was to evaluate the longer-term safety and efficacy of drug-eluting stents (DES) in off-label indications as compared with bare-metal stents (BMS)...
  81. ncbi request reprint The use of hip protectors in long-term care facilities: a survey of nursing home staff
    Anna M Sawka
    Division of Endocrinology and Department of Medicine, University Health Network and University of Toronto, Ontario, Canada
    J Am Med Dir Assoc 8:229-32. 2007
    ..To determine the level of exposure to hip protectors and barriers to their use in nursing homes...
  82. ncbi request reprint Health economic evaluations help inform payers of the best use of scarce health care resources
    Daria O'Reilly
    Programs for Assessment of Technology in Health Research Institute, McMaster University, Hamilton, Canada
    Int J Circumpolar Health 70:417-27. 2011
    ..e., opportunity costs). The objective of this paper is to provide an overview of economic evaluations and how these tools can be used to help inform payers of the best use of scarce health care resources...
  83. doi request reprint Ontario multidetector computed tomographic coronary angiography study: field evaluation of diagnostic accuracy
    Benjamin J W Chow
    Department of Radiology, University of Ottawa Heart Institute, Ontario, Canada
    Arch Intern Med 171:1021-9. 2011
    ..The true diagnostic accuracy of CTCA in the "real world" remains uncertain. We conducted a field evaluation comparing multidetector CTCA with invasive CA (ICA) to understand CTCA's diagnostic accuracy in a real-world setting...
  84. doi request reprint Practice and physician characteristics associated with influenza vaccination delivery rates following a patient reminder letter intervention
    Kelly K Anderson
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Prim Prev 29:93-7. 2008
    ..Examining other physician and practice factors associated with vaccination delivery following a reminder letter campaign may help improve such prevention efforts...
  85. ncbi request reprint The cost of laparoscopic myotomy versus pneumatic dilatation for esophageal achalasia
    Paul J Karanicolas
    Department of Surgery, The University of Western Ontario, London, Canada
    Surg Endosc 21:1198-206. 2007
    ..The two main treatment options for esophageal achalasia are laparoscopic distal esophageal myotomy (LM) and pneumatic dilatation (PD). Our objective was to compare the costs of these management strategies...
  86. doi request reprint Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial)
    Andrea Manca
    Centre for Health Economics, Alcuin A Block, University of York, York YO10 5DD, United Kingdom
    Eur J Pain 12:1047-58. 2008
    ..Chronic back and leg pain conditions result in patients' loss of function, reduced quality of life and increased costs to the society...
  87. ncbi request reprint Probabilistic analysis of cost-effectiveness models: choosing between treatment strategies for gastroesophageal reflux disease
    Andrew H Briggs
    Health Economics Research Centre, University of Oxford, Institute of Health Sciences, Headington, United Kingdom
    Med Decis Making 22:290-308. 2002
    ..It is argued that probabilistic analyses should be encouraged because they have potential to quantify the strength of evidence in favor of particular treatment choices...
  88. ncbi request reprint Validation of the GSFQ, a self-administered symptom frequency questionnaire for patients with gastroesophageal reflux disease
    Pierre Pare
    Division of Gastroenterology, Centre Hospitalier Affilié Universitaire de Québec Hôpital St Sacrement, 1050 Chemin Ste Foy, Quebec City, Quebec G1S 4L8, Canada
    Can J Gastroenterol 17:307-12. 2003
    ..The present article presents the validation of the short, self-administered GERD Symptom Frequency Questionnaire (GSFQ)...
  89. ncbi request reprint Methods for patient-level costing in the VA system: are they applicable to Canada?
    Gordon Blackhouse
    McMaster University, St Joseph s Hospital
    Med Care Res Rev 60:142S-145S. 2003
  90. ncbi request reprint Antiviral agents for influenza: a comparison of cost-effectiveness data
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Pharmacoeconomics 23:1083-106. 2005
    ....
  91. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
    ..g. enoxaparin) as thromboprophylaxis for the prevention of deep vein thrombosis (DVT)...
  92. ncbi request reprint Unfinished symphony: a tribute to the life and career of Bernie O'Brien (1959-2004)
    Andrew Briggs
    Centre for Health Economics, University of York, Heslington, York, United Kingdom
    Med Decis Making 24:538-44. 2004
    ..He was also an excellent communicator and teacher and, above all, a fun guy to work with. In this article, the authors provide a review of Bernie's academic contributions...
  93. doi request reprint Money matters: what to look for in an economic analysis
    Lea M Dijksman
    Department of Orthopaedic Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Acta Orthop 79:1-11. 2008
  94. ncbi request reprint Country specific cost comparisons from multinational clinical trials using empirical Bayesian shrinkage estimation: the Canadian ASSENT-3 economic analysis
    Andrew R Willan
    Program in Population Health Sciences, Sick Kids Research Institute, and Department of Public Health Sciences, University of Toronto, Canada
    Health Econ 14:327-38. 2005
    ..The approaches are illustrated and compared using the data from the ASSENT-3 trial...
  95. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
    ..g. enoxaparin) as thromboprophylaxis for the prevention of deep vein thrombosis (DVT)...
  96. ncbi request reprint The cost-effectiveness of extended-duration antithrombotic prophylaxis after total hip arthroplasty
    Chris Skedgel
    Department of Medicine, Dalhousie University, Centre for Clinical Research, University Avenue, Halifax, Canada
    J Bone Joint Surg Am 89:819-28. 2007
    ....
  97. ncbi request reprint Effectiveness and safety of drug-eluting stents in Ontario
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ont, Canada
    N Engl J Med 357:1393-402. 2007
    ..However, there is uncertainty about the effectiveness of drug-eluting stents, and increasing concern about their safety, in routine clinical practice...
  98. ncbi request reprint Economics methods in the Clinical Outcomes Utilizing percutaneous coronary Revascularization and Aggressive Guideline-driven drug Evaluation (COURAGE) trial
    William S Weintraub
    Atlanta VA Medical Center, Decatur, GA, USA
    Am Heart J 151:1180-5. 2006
    ..A multilevel regression model will assess cost-effectiveness from a net benefit perspective. These approaches should provide the most detailed assessment available of the cost-effectiveness of PCI for coronary artery disease...
  99. doi request reprint Effect of PCI on quality of life in patients with stable coronary disease
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 359:677-87. 2008
    ..It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease...
  100. doi request reprint Cardiovascular Health Awareness Program (CHAP): a community cluster-randomised trial among elderly Canadians
    Janusz Kaczorowski
    Department of Family Practice, University of British Columbia, Canada
    Prev Med 46:537-44. 2008
    ..The present study is a community cluster-randomised trial testing the effectiveness of CHAP (Cardiovascular Health Awareness Program) on the cardiovascular health of older adults...
  101. ncbi request reprint Primary data collection in health technology assessment
    Michelle L McIsaac
    McGill University and University of Montreal Health Centres, and Department of Community Health Sciences, University of Calgary, 1403 29 Street NW, Calgary, Alberta, Canada
    Int J Technol Assess Health Care 23:24-9. 2007
    ..The authors conclude that, under specific conditions, primary data collection is a worthwhile endeavor in the HTA process...