Research Topics
Species | Martin GibalaSummaryAffiliation: McMaster University Country: Canada Publications
| Collaborators
|
Detail Information
Publications
Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performanceMartin J Gibala
Department of Kinesiology IWC AB122, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
J Physiol 575:901-11. 2006..05). Given the large difference in training volume, these data demonstrate that SIT is a time-efficient strategy to induce rapid adaptations in skeletal muscle and exercise performance that are comparable to ET in young active men...
Protein metabolism and endurance exerciseMartin J Gibala
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Sports Med 37:337-40. 2007....- High-intensity interval training: a time-efficient strategy for health promotion?Martin J Gibala
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Curr Sports Med Rep 6:211-3. 2007 - Physiological adaptations to low-volume, high-intensity interval training in health and diseaseMartin J Gibala
Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 Canada
J Physiol 590:1077-84. 2012..Finally, we provide insight on the utility of low-volume HIT for improving performance in athletes and highlight suggestions for future research... 
Molecular responses to high-intensity interval exerciseMartin Gibala
Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
Appl Physiol Nutr Metab 34:428-32. 2009....- Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1alpha in human skeletal muscleMartin J Gibala
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Appl Physiol 106:929-34. 2009.... - Metabolic adaptations to short-term high-intensity interval training: a little pain for a lot of gain?Martin J Gibala
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Exerc Sport Sci Rev 36:58-63. 2008.... - PDH activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humansM J Gibala
Copenhagen Muscle Research Center, Rigshospitalet, DK 2200 Copenhagen N, Denmark
Am J Physiol 277:E33-8. 1999.... - Exercise with low muscle glycogen augments TCA cycle anaplerosis but impairs oxidative energy provision in humansMartin J Gibala
Copenhagen Muscle Research Centre, Rigshospitalet section 7652, DK 2200 Copenhagen, Denmark
J Physiol 540:1079-86. 2002.... - Anaplerosis of the muscle tricarboxylic acid cycle pool during contraction: does size matter?Martin J Gibala
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S 4K1
J Physiol 548:334. 2003 - Myofibrillar disruption following acute concentric and eccentric resistance exercise in strength-trained menM J Gibala
Department of Kinesiology Neurology and Neurological Rehabilitation, McMaster University, Hamilton, ON, Canada
Can J Physiol Pharmacol 78:656-61. 2000..Moreover, it appears that fibre disruption induced by habitual weightlifting exercise is essentially repaired after 5 days of inactivity in trained men... - Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humansM J Gibala
Departments of Kinesiology and Medicine, McMaster University, Hamilton, Ontario L8S 4K1
J Appl Physiol 87:1662-7. 1999..Moreover, it appears that low resting glycogen per se does not impair the increase in TCAI during moderate exercise... - Dissociation between muscle tricarboxylic acid cycle pool size and aerobic energy provision during prolonged exercise in humansMartin J Gibala
Copenhagen Muscle Research Centre, Rigshospitalet section 7652, DK 2200 Copenhagen, Denmark
J Physiol 545:705-13. 2002..We conclude that there is a progressive decrease in muscle [TCAI] during prolonged exercise in humans; however this decrease does not compromise aerobic energy provision and is not attributable to the depletion of muscle [glycogen]... - Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetesJonathan P Little
Dept of Kinesiology, McMaster University, Hamilton, Canada
J Appl Physiol 111:1554-60. 2011..05). Our findings indicate that low-volume HIT can rapidly improve glucose control and induce adaptations in skeletal muscle that are linked to improved metabolic health in patients with type 2 diabetes... - A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanismsJonathan P Little
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Physiol 588:1011-22. 2010..The results also suggest that increases in SIRT1, nuclear PGC-1alpha, and Tfam may be involved in coordinating mitochondrial adaptations in response to HIT in human skeletal muscle... - Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humansAndrew J R Cochran
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, Canada
J Appl Physiol 108:628-36. 2010.... - Effect of endurance training on muscle TCA cycle metabolism during exercise in humansKrista R Howarth
Exercise Metabolism Research Group, Department of Kinesiology, IWC Rm. AB122, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Appl Physiol 97:579-84. 2004..6 +/- 0.3 mmol/kg dry wt; P < 0.05), which is consistent with reduced carbon flux through alanine aminotransferase. We conclude that, after aerobic training, cycle endurance capacity is not limited by a decrease in muscle [TCAI]... - Acute endurance exercise increases the nuclear abundance of PGC-1alpha in trained human skeletal muscleJonathan P Little
Department of Kinesiology, McMaster University, Ivor Wynne Centre, Hamilton, ON L8S 4K1
Am J Physiol Regul Integr Comp Physiol 298:R912-7. 2010.... - Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humansKirsten A Burgomaster
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Physiol 586:151-60. 2008.... - Tricarboxylic acid cycle intermediates accumulate at the onset of intense exercise in man but are not essential for the increase in muscle oxygen uptakeJens Bangsbo
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Pflugers Arch 452:737-43. 2006..Am J Physiol 282:R273-R280, 2002), the present data suggest that muscle TCAI accumulate during the initial seconds of exercise; however, this increase is not essential for the contraction-induced increase in mitochondrial respiration... - Short-term training attenuates muscle TCA cycle expansion during exercise in womenKristen D Dawson
Department of Kinesiology, McMaster University, Hamilton, ON, Canada L8S 4K1
J Appl Physiol 95:999-1004. 2003..05). We conclude that 1). the contraction-induced increase in flux through AAT is reduced after 5 days of aerobic training and 2). the muscle glycogenolytic response during exercise after STT in women is similar to that in men... - Six sessions of sprint interval training increases muscle oxidative potential and cycle endurance capacity in humansKirsten A Burgomaster
Exercise Metabolism Research Group, Dept. of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Appl Physiol 98:1985-90. 2005..We conclude that short sprint interval training (approximately 15 min of intense exercise over 2 wk) increased muscle oxidative potential and doubled endurance capacity during intense aerobic cycling in recreationally active individuals... - Effect of short-term sprint interval training on human skeletal muscle carbohydrate metabolism during exercise and time-trial performanceKirsten A Burgomaster
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
J Appl Physiol 100:2041-7. 2006..8+/-1.2 vs. pretraining: 18.9+/-1.2 min; P=0.74). We conclude that short-term SIT improved cycling TT performance and resulted in a closer matching of glycogenolytic flux and pyruvate oxidation during submaximal exercise... - Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercisePaul J Leblanc
Department of Medicine, McMaster University Health Science Centre, Hamilton, ON, Canada L8N 3Z5
J Appl Physiol 97:2148-53. 2004..post-Tr: 28.6 +/- 5.6 mmol/kg dry wt). We have demonstrated for the first time that several signals act to coordinately regulate Phos and PDH, and thus carbohydrate metabolism, in human skeletal muscle after 7 wk of endurance training... - Coingestion of protein with carbohydrate during recovery from endurance exercise stimulates skeletal muscle protein synthesis in humansKrista R Howarth
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
J Appl Physiol 106:1394-402. 2009..However, adding protein or additional CHO to a feeding strategy that provided 1.2 g CHO x kg(-1) x h(-1) did not further enhance glycogen resynthesis during recovery... - An acute decrease in TCA cycle intermediates does not affect aerobic energy delivery in contracting rat skeletal muscleKristen D Dawson
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada L8S 4K1
J Physiol 565:637-43. 2005..These data do not support the hypothesis that the total muscle concentration of TCAI is causally linked to the rate of mitochondrial respiration during contraction... - Muscle metabolism during exercise with carbohydrate or protein-carbohydrate ingestionNaomi M Cermak
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Ontario, Canada
Med Sci Sports Exerc 41:2158-64. 2009.... - Exercise training increases branched-chain oxoacid dehydrogenase kinase content in human skeletal muscleKrista R Howarth
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 293:R1335-41. 2007..Biochem Mol Biol Int 44: 1211-1216, 1998)... - Resistance training with vascular occlusion: metabolic adaptations in human muscleKirsten A Burgomaster
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 35:1203-8. 2003..OCC potentiated the metabolic changes, perhaps by inducing an ischemic stimulus that enhanced muscle glucose transport and adenine nucleotide catabolism after LIT, but did not augment the increases in strength... - Neuromuscular adaptations in human muscle following low intensity resistance training with vascular occlusionDaniel R Moore
Department of Kinesiology, Exercise and Metabolism Research Group, McMaster University, 1280 Main St. W, Hamilton, Ontario, L8S 4K1, Canada
Eur J Appl Physiol 92:399-406. 2004.... - Divergent response of metabolite transport proteins in human skeletal muscle after sprint interval training and detrainingKirsten A Burgomaster
Exercise Metabolism Research Group, Dept of Kinesiology, McMaster Univ, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 292:R1970-6. 2007..05). We conclude that short-term SIT induces rapid increases in skeletal muscle oxidative capacity but has divergent effects on proteins associated with glucose, lactate, and fatty acid transport... - Enhanced pyruvate dehydrogenase activity does not affect muscle O2 uptake at onset of intense exercise in humansJens Bangsbo
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark
Am J Physiol Regul Integr Comp Physiol 282:R273-80. 2002..The present findings demonstrate that increasing PDH(a) does not alter muscle O2 uptake and anaerobic ATP provision during the initial phase of intense dynamic knee-extensor exercise in humans... - Sprint interval and traditional endurance training induce similar improvements in peripheral arterial stiffness and flow-mediated dilation in healthy humansMark Rakobowchuk
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 295:R236-42. 2008..However, alterations in central artery distensibility may require a longer training stimuli and/or greater initial vascular stiffness than observed in this group of healthy subjects... - Effects of recovery method after exercise on performance, immune changes, and psychological outcomesDouglas L Stacey
Fowler Kennedy Sports Medicine Clinic, London, ON, Canada
J Orthop Sports Phys Ther 40:656-65. 2010..Randomized controlled trial using a repeated-measures design... - Failure of protein to improve time trial performance when added to a sports drinkMartin van Essen
Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Med Sci Sports Exerc 38:1476-83. 2006..However, adding 2% protein to a 6% carbohydrate drink provided no additional performance benefit during a task that closely simulated the manner in which athletes typically compete... - An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscleJonathan P Little
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 300:R1303-10. 2011..These findings support the hypothesis that an acute bout of low-volume HIT activates mitochondrial biogenesis through a mechanism involving increased nuclear abundance of PGC-1α... - Glycogen availability does not affect the TCA cycle or TAN pools during prolonged, fatiguing exerciseJacinta Baldwin
Department of Physiology, University of Melbourne, Parkville 3010, Victoria, Australia
J Appl Physiol 94:2181-7. 2003..Therefore, our data do not support the concept that a decrease in muscle TCAI during prolonged exercise in humans compromises aerobic energy provision or is the cause of fatigue... - Nutritional strategies to influence adaptations to trainingLawrence L Spriet
Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
J Sports Sci 22:127-41. 2004..Research in these areas in the coming years will lead to strategies designed to improve the adaptive response to training...