Genomes and Genes
Markus B Geuking
Affiliation: McMaster University
- Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integrationMarkus B Geuking
Institute of Experimental Immunology, University Hospital Zurich, Schmelzbergstrasse 12, 8091 Zurich, Switzerland
Science 323:393-6. 2009..Thus, RNA viruses should be closely scrutinized for any capacity to interact with endogenous retroviral elements before their approval for therapeutic use in humans...
- Natural IgE production in the absence of MHC Class II cognate helpKathy D McCoy
Institute of Experimental Immunology, Department of Pathology, Universitatsspital, Schmelzbergstrasse 12, CH 8091 Zurich, Switzerland
Immunity 24:329-39. 2006..The pathway of spontaneous IgE production is not inhibited by regulatory T cells and increases with age to constitute significant serum concentrations, even in naive animals...
- Absence of CTL responses to early viral antigens facilitates viral persistenceAnita Schildknecht
Institute of Experimental Immunology, University Hospital Zurich, Zurich, Switzerland
J Immunol 180:3113-21. 2008..Thus, the kinetics with which virus-derived T cell epitopes are presented has a strong impact on the efficacy of the antiviral immunity. This aspect should be taken into consideration for the development of vaccines...
- Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoireWeldy V Bonilla
Institute of Experimental Immunology, Department of Pathology, University Hospital Zurich, Zurich, Switzerland
J Clin Invest 116:156-62. 2006....