M J Farquharson

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. doi request reprint Zinc presence in invasive ductal carcinoma of the breast and its correlation with oestrogen receptor status
    M J Farquharson
    Department of Medical Physics and Applied Radiation Sciences, McMaster University, Ontario, Canada Department of Radiography, City Community and Health Sciences, City University, London, UK
    Phys Med Biol 54:4213-23. 2009
  2. doi request reprint The distribution of trace elements Ca, Fe, Cu and Zn and the determination of copper oxidation state in breast tumour tissue using muSRXRF and muXANES
    M J Farquharson
    Department of Radiography, City Community and Health Sciences, City University, London, EC1V 0HB, UK
    Phys Med Biol 53:3023-37. 2008
  3. doi request reprint The evaluation of biologically important trace metals in liver, kidney and breast tissue
    A Al-Ebraheem
    Department of Radiography, Institute of Community and Health Sciences, City University, Northampton Square, London EC1V 0HB, UK
    Appl Radiat Isot 67:470-4. 2009
  4. ncbi request reprint X-ray fluorescence and energy dispersive x-ray diffraction for the quantification of elemental concentrations in breast tissue
    K Geraki
    Department of Radiography, City University, Rutland Place, Charterhouse Square, London EC1M 6PA, UK
    Phys Med Biol 49:99-110. 2004
  5. ncbi request reprint The localisation and micro-mapping of copper and other trace elements in breast tumours using a synchrotron micro-XRF system
    M J Farquharson
    Department of Radiography, School of Allied Health Sciences, City University, London EC1V 0HB, UK
    Appl Radiat Isot 65:183-8. 2007
  6. doi request reprint Human soft tissue analysis using x-ray or gamma-ray techniques
    C Theodorakou
    City Community and Health Sciences, City University, Northampton Sq, London, EC1V 0HB, UK
    Phys Med Biol 53:R111-49. 2008
  7. ncbi request reprint Concentrations of Fe, Cu and Zn in breast tissue: a synchrotron XRF study
    K Geraki
    Department of Radiography, City University, London, UK
    Phys Med Biol 47:2327-39. 2002
  8. doi request reprint Influence of zinc and zinc chelator on HT-29 colorectal cell line
    K S Gurusamy
    University Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Biometals 24:143-51. 2011

Collaborators

  • C Theodorakou
  • A L Harris
  • K Geraki
  • K S Gurusamy
  • A Al-Ebraheem
  • D A Bradley
  • N Farooqui
  • S Whiting
  • M Loizidou
  • B R Davidson
  • S Dijk
  • B J Fuller
  • J W Taanman
  • E Ryan

Detail Information

Publications8

  1. doi request reprint Zinc presence in invasive ductal carcinoma of the breast and its correlation with oestrogen receptor status
    M J Farquharson
    Department of Medical Physics and Applied Radiation Sciences, McMaster University, Ontario, Canada Department of Radiography, City Community and Health Sciences, City University, London, UK
    Phys Med Biol 54:4213-23. 2009
    ..When comparing the increase in zinc in the tumour regions expressed as a percentage of the surrounding non-tumour tissue zinc level in the same sample, a significant difference between the ER+ve and ER-ve samples was found (P < 0.01)...
  2. doi request reprint The distribution of trace elements Ca, Fe, Cu and Zn and the determination of copper oxidation state in breast tumour tissue using muSRXRF and muXANES
    M J Farquharson
    Department of Radiography, City Community and Health Sciences, City University, London, EC1V 0HB, UK
    Phys Med Biol 53:3023-37. 2008
    ..However, the shape of the spectra does not exclude the presence of Cu+. Tumour regions were found to have a higher fraction of Cu+ compared to the normal samples...
  3. doi request reprint The evaluation of biologically important trace metals in liver, kidney and breast tissue
    A Al-Ebraheem
    Department of Radiography, Institute of Community and Health Sciences, City University, Northampton Square, London EC1V 0HB, UK
    Appl Radiat Isot 67:470-4. 2009
    ..The distributions were compared to reference images and higher concentrations of metals correlated with areas of cancer cells. The average increase of Ca, Fe, Cu and Zn concentrations in areas of malignancy were 70%, 43%, 53% and 87%...
  4. ncbi request reprint X-ray fluorescence and energy dispersive x-ray diffraction for the quantification of elemental concentrations in breast tissue
    K Geraki
    Department of Radiography, City University, Rutland Place, Charterhouse Square, London EC1M 6PA, UK
    Phys Med Biol 49:99-110. 2004
    ..The measurement precision was between 1% and 9% while the calculated uncertainties on the final elemental concentrations ranged between 10% and 16%...
  5. ncbi request reprint The localisation and micro-mapping of copper and other trace elements in breast tumours using a synchrotron micro-XRF system
    M J Farquharson
    Department of Radiography, School of Allied Health Sciences, City University, London EC1V 0HB, UK
    Appl Radiat Isot 65:183-8. 2007
    ..Correlation of these distributions with the concentrations of cancer cells was achieved in some samples...
  6. doi request reprint Human soft tissue analysis using x-ray or gamma-ray techniques
    C Theodorakou
    City Community and Health Sciences, City University, Northampton Sq, London, EC1V 0HB, UK
    Phys Med Biol 53:R111-49. 2008
    ..The soft tissues that have been classified using x-rays or gamma rays include brain, breast, colon, fat, kidney, liver, lung, muscle, prostate, skin, thyroid and uterus...
  7. ncbi request reprint Concentrations of Fe, Cu and Zn in breast tissue: a synchrotron XRF study
    K Geraki
    Department of Radiography, City University, London, UK
    Phys Med Biol 47:2327-39. 2002
    ..6 for the paired samples and 2.7 for the non-paired samples. The ratios describing copper content were 3.1 for paired and 3.6 for non-paired samples while for zinc they were 2.4 and 4.4 respectively...
  8. doi request reprint Influence of zinc and zinc chelator on HT-29 colorectal cell line
    K S Gurusamy
    University Department of Surgery, Royal Free Campus, UCL Medical School, London, UK
    Biometals 24:143-51. 2011
    ..HT-29 cells are not able to counteract the effect of intracellular chelation of zinc by altering zinc transport. Further research into the mechanisms of these findings is necessary and may lead to novel therapeutic options...