L Elit

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi request reprint Use of systemic therapy in women with recurrent ovarian cancer--development of a national clinical practice guideline
    L Elit
    Juravinski Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 106:181-92. 2007
  2. ncbi request reprint Prophylactic oophorectomy in Ontario
    L Elit
    Department of Obstetrics and Gynecology, MacMaster University, Hamilton, Ontario, Canada
    Fam Cancer 1:143-8. 2001
  3. ncbi request reprint Quality of life and psychosexual adjustment after prophylactic oophorectomy for a family history of ovarian cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Fam Cancer 1:149-56. 2001
  4. ncbi request reprint Optimal management for surgically Stage 1 serous cancer of the uterus
    L Elit
    Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 92:240-6. 2004
  5. ncbi request reprint Job satisfaction, stress, and burnout among Canadian gynecologic oncologists
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Canada
    Gynecol Oncol 94:134-9. 2004
  6. pmc Endometrial cancer. Prevention, detection, management, and follow up
    L Elit
    Hamilton Regional Cancer Centre, Division of Gynecologic Oncology, ON
    Can Fam Physician 46:887-92. 2000
  7. ncbi request reprint Steppe by steppe: gynecological oncology on the Mongolian plains
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Int J Gynecol Cancer 15:359-60. 2005
  8. ncbi request reprint Invasive vulvar cancer in a woman with human immunodeficiency virus: case report and review of the literature
    L Elit
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, McMaster University, Juravinski Cancer Centre, 699 Concession Street, Hamilton, Ontario, Canada
    Gynecol Oncol 98:151-4. 2005
  9. ncbi request reprint Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer
    Laurie Elit
    Juravinski Cancer Centre, 699 Concession Street, Hamilton, ON L8V 5C2, Canada
    IDrugs 9:636-44. 2006
  10. ncbi request reprint Outcomes for systemic therapy in women with ovarian cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Juravinski Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 103:554-8. 2006

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Use of systemic therapy in women with recurrent ovarian cancer--development of a national clinical practice guideline
    L Elit
    Juravinski Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 106:181-92. 2007
    ..This will be done using a standardized systematic review process, guideline evaluation instruments, multi-disciplinary expert consensus opinion and evidence-rating systems...
  2. ncbi request reprint Prophylactic oophorectomy in Ontario
    L Elit
    Department of Obstetrics and Gynecology, MacMaster University, Hamilton, Ontario, Canada
    Fam Cancer 1:143-8. 2001
    ..To determine the indications, patterns of practice, and complication rates for prophylactic oophorectomy in Ontario...
  3. ncbi request reprint Quality of life and psychosexual adjustment after prophylactic oophorectomy for a family history of ovarian cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Fam Cancer 1:149-56. 2001
    ..2) To explore the potential costs related to surgery such a menopausal symptoms and satisfaction with sexual functioning...
  4. ncbi request reprint Optimal management for surgically Stage 1 serous cancer of the uterus
    L Elit
    Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 92:240-6. 2004
    ..To describe the outcomes of patients who have undergone well-conducted surgery and found to have Stage 1 serous uterine cancer...
  5. ncbi request reprint Job satisfaction, stress, and burnout among Canadian gynecologic oncologists
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Canada
    Gynecol Oncol 94:134-9. 2004
    ..1). To provide a job description of Canadian gynecologic oncologists. (2). To assess job satisfaction and job stress, and measure the prevalence of burnout and psychological morbidity...
  6. pmc Endometrial cancer. Prevention, detection, management, and follow up
    L Elit
    Hamilton Regional Cancer Centre, Division of Gynecologic Oncology, ON
    Can Fam Physician 46:887-92. 2000
    ..To review risk factors for uterine cancer; to discuss strategies for detecting uterine cancer; to outline prognostic factors and treatment; and to review the role of follow up for patients who have completed primary therapy...
  7. ncbi request reprint Steppe by steppe: gynecological oncology on the Mongolian plains
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Int J Gynecol Cancer 15:359-60. 2005
    ..Partnering with our colleagues in developing countries is a personally enriching experience. The development of gynecologic cancer care must ultimately be culturally relevant...
  8. ncbi request reprint Invasive vulvar cancer in a woman with human immunodeficiency virus: case report and review of the literature
    L Elit
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, McMaster University, Juravinski Cancer Centre, 699 Concession Street, Hamilton, Ontario, Canada
    Gynecol Oncol 98:151-4. 2005
    ..HIV is associated with a decrease in cellular immunity which allows for persistence of high-risk HPV types and this can predispose the woman to dysplasia or cancer of the gynecologic tract...
  9. ncbi request reprint Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer
    Laurie Elit
    Juravinski Cancer Centre, 699 Concession Street, Hamilton, ON L8V 5C2, Canada
    IDrugs 9:636-44. 2006
    ....
  10. ncbi request reprint Outcomes for systemic therapy in women with ovarian cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Juravinski Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 103:554-8. 2006
    ..To describe the association of systemic therapy delivery with overall survival for ovarian cancer...
  11. ncbi request reprint Assessment of 2 cervical screening methods in Mongolia: cervical cytology and visual inspection with acetic acid
    L Elit
    Division of Gynecologic Oncology, McMaster University, Hamilton, Ontario, Canada
    J Low Genit Tract Dis 10:83-8. 2006
    ..The aim of the study was to evaluate the test parameters of visual inspection with acetic acid (VIA) and cervical cytology in 3 Mongolian aimags...
  12. pmc Surgical outcomes in women with ovarian cancer
    Laurie M Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ont
    Can J Surg 51:346-54. 2008
    ..We sought to assess whether the specialty of the surgeon or the hospital involved in the initial management of women with ovarian cancer determined the likelihood of unnecessary repeated abdominal surgery and long-term patient survival...
  13. ncbi request reprint Outcomes in surgery for ovarian cancer
    L Elit
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Gynecol Oncol 87:260-7. 2002
    ....
  14. ncbi request reprint Novel strategies for systemic treatment of endometrial cancer
    L Elit
    Division of Gynecologic Oncology, Hamilton Regional Cancer Centre, 699 Concession Street, Hamilton, Ontario, L8V 5C2, Canada
    Expert Opin Investig Drugs 9:2831-53. 2000
    ..e., Herceptintrade mark). Exciting developments in the understanding of the molecules involved in tumour development and metastasis will allow the development of specific and selective inhibitors...
  15. pmc Familial ovarian cancer
    L Elit
    Hamilton Regional Cancer Centre
    Can Fam Physician 47:778-84. 2001
    ..To assist family physicians in evaluating patients' risk for hereditary ovarian cancer and to review strategies for preventing ovarian cancer...
  16. ncbi request reprint A unique BRCA1 mutation identified in Mongolia
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Canada
    Int J Gynecol Cancer 11:241-3. 2001
    ..The only preventive management strategy available in the third world is prophylactic surgery...
  17. ncbi request reprint Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer
    Laurie Elit
    Division of Gynecologic Oncology, MacMaster University, Hamilton, Ontario, Canada
    Curr Opin Obstet Gynecol 14:67-73. 2002
    ..Exciting developments in understanding the molecules involved in tumour development and metastasis will allow the development of specific and selective inhibitors...
  18. ncbi request reprint Women's perceptions about treatment decision making for ovarian cancer
    L Elit
    Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
    Gynecol Oncol 88:89-95. 2003
    ....
  19. ncbi request reprint CCI-779 Wyeth
    Laurie Elit
    Hamilton Regional Cancer Center, Ontario, Canada
    Curr Opin Investig Drugs 3:1249-53. 2002
    ....
  20. doi request reprint The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation
    A Finch
    Women s College Research Institute, Women s College Hospital, Toronto, ON, Canada
    Gynecol Oncol 121:163-8. 2011
    ..We measured the impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual functioning in women with a BRCA mutation...
  21. ncbi request reprint Risk factors for ovarian cancer and early-onset breast cancer in Mongolia
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Toronto, Canada
    Eur J Gynaecol Oncol 23:397-400. 2002
    ..To determine if there are founder BRCA1 mutations in the Mongolian population...
  22. ncbi request reprint Patterns of care in the initial management of women with vulvar cancers in Ontario
    L Elit
    Department of Obstetrics and Gynecology and Surgery, McMaster University, Hamilton, Canada
    Eur J Gynaecol Oncol 30:503-5. 2009
    ..To facilitate the planning of future resources for cancer services in Ontario, Cancer Care Ontario commissioned an evaluation of operative services delivered for vulvar cancer...
  23. ncbi request reprint Patterns of care for the initial management of cervical cancer in Ontario
    L Elit
    Department of Obstetrics and Gynecology and Surgery, McMaster University, Hamilton, Canada
    Eur J Gynaecol Oncol 30:493-6. 2009
    ..To facilitate the planning of resources for cancer services in Ontario, Cancer Care Ontario commissioned an evaluation of operative services delivered for cervical cancer...
  24. ncbi request reprint Patterns of care in the initial management of women with ovarian cancer in Ontario
    L Elit
    Department of Obstetrics and Gynecology and Surgery, McMaster University, Hamilton, Canada
    Eur J Gynaecol Oncol 30:361-4. 2009
    ..The investigations and consults around the time of diagnosis are described...
  25. doi request reprint It's a choice to move forward: women's perceptions about treatment decision making in recurrent ovarian cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ont, Canada
    Psychooncology 19:318-25. 2010
    ....
  26. ncbi request reprint Breast and ovarian cancer risk perception after prophylactic salpingo-oophorectomy due to an inherited mutation in the BRCA1 or BRCA2 gene
    A Finch
    Women s College Research Institute, Toronto, ON, Canada
    Clin Genet 75:220-4. 2009
    ..However, in this study, many women overestimated their risk of ovarian cancer, particularly women who carry a BRCA2 mutation...
  27. doi request reprint Sociodemographic factors associated with cervical cancer screening coverage and follow-up of high grade abnormal results in a population-based cohort
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Gynecol Oncol 128:95-100. 2013
    ..A cervical cytology based screening program is effective if there is regular screening of the 'at risk' population and close follow-up of those labeled abnormal...
  28. ncbi request reprint Concurrent cisplatin-based chemotherapy plus radiotherapy for cervical cancer--a meta-analysis
    H Lukka
    Hamilton Regional Cancer Centre, Ontario, Canada
    Clin Oncol (R Coll Radiol) 14:203-12. 2002
    ..To evaluate the role of concurrent cisplatin plus radiotherapy in the treatment of cervical cancer...
  29. ncbi request reprint Prognostic factors for women with Stage 1 ovarian cancer with or without adhesions
    S Bondy
    Department of Public Health Sciences, University of Toronto, Ontario, Canada
    Eur J Gynaecol Oncol 27:585-8. 2006
    ..To identify those prognostic factors in women with Stage 1 epithelial ovarian cancer that predict survival...
  30. ncbi request reprint Familial and hormonal risk factors for papillary serous uterine cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada
    Eur J Gynaecol Oncol 23:187-90. 2002
    ..To identify genetic and non-genetic risk factors for papillary serous uterine cancer...
  31. ncbi request reprint Physicians' attitudes, beliefs and knowledge concerning ovarian cancer
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Ontario, Canada
    Eur J Gynaecol Oncol 27:19-24. 2006
    ..To determine physicians' attitudes, beliefs and knowledge concerning surgical care of women with ovarian cancer...
  32. ncbi request reprint Chemotherapy for recurrent epithelial ovarian cancer previously treated with platinum--a systematic review of the evidence from randomized trials
    M Fung Kee Fung
    Department of Obstetrics and Gynaecology, University of Ottawa, ON, Canada
    Eur J Gynaecol Oncol 23:104-10. 2002
    ..To evaluate the chemotherapeutic options for women with recurrent epithelial ovarian cancer who have received platinum-based chemotherapy...
  33. ncbi request reprint Colposcopists' agreement on cervical biopsy site
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada
    Clin Exp Obstet Gynecol 34:88-90. 2007
    ..To determine the inter-observer agreement among colposcopists on the most abnormal area of the cervix from which a biopsy would be obtained and whether any attributes predict agreement...
  34. ncbi request reprint Does shifting a physician payment system shift physician priorities? A multi-site evaluation of an alternative payment plan (APP) for gynecologic oncologists in Ontario
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada
    Eur J Gynaecol Oncol 27:375-8. 2006
    ..The objective of this study was to attempt to understand how changing the mode of reimbursement alters physician behavior from the physician's perspective...
  35. ncbi request reprint Giving patients information on abnormal cytology and human papillomavirus: survey of health providers
    M Howard
    Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada
    Eur J Gynaecol Oncol 28:15-7. 2007
    ..Knowledge of the link between HPV and cervical cancer is low among women. Health providers may be required to give information and counseling on HPV. This study surveyed health providers' comfort in counseling women about HPV...
  36. ncbi request reprint Surgery as sole treatment for serous borderline tumors of the ovary with noninvasive implants
    F Lackman
    Division of Gynecologic Oncology, London Health Sciences Centre, London, Ontario, Canada
    Gynecol Oncol 90:407-12. 2003
    ..The objectives were to describe the clinical characteristics and prognosis of surgically treated patients with stage II and III serous borderline tumors of the ovary with noninvasive implants...
  37. ncbi request reprint Patterns of surgical care for uterine cancers in Ontario
    L Elit
    Department of Obstetrics and Gynecology and Surgery, McMaster University, Hamilton Institute for Clinical Evaluative Sciences ICES, Toronto, Canada
    Eur J Gynaecol Oncol 30:255-8. 2009
    ..To facilitate the planning of future resources for cancer services in Ontario, Cancer Care Ontario commissioned an evaluation of operative services delivered for uterine cancer...
  38. ncbi request reprint Cutaneous metastasis of papillary serous uterine cancer
    L Elit
    Department of Obstetrics and Gynecology, Hamilton Regional Cancer Centre, Hamilton, Canada
    Gynecol Oncol 82:208-11. 2001
    ..Cutaneous metastases from uterine cancer are uncommon. They usually indicate the aggressive nature of the underlying disease...
  39. ncbi request reprint Systematic review of adjuvant care for women with Stage I ovarian carcinoma
    Laurie Elit
    Division of Gynecologic Oncology, Juravinski Regional Cancer Centre, Hamilton, Ontario, Canada
    Cancer 101:1926-35. 2004
    ..Several adjuvant care interventions to treat women with Stage I ovarian carcinoma have been studied. The aim of the current systematic review was to determine the optimal strategy for adjuvant care for women with Stage I ovarian carcinoma...
  40. ncbi request reprint Chemotherapy for recurrent, metastatic, or persistent cervical cancer: a systematic review
    H W Hirte
    Department of Medical Oncolgy, Juravinski Regional Cancer Centre, Hamilton, Ontario, Canada
    Int J Gynecol Cancer 17:1194-204. 2007
    ..Further randomized trials are needed to inform the role of single-agent or combination chemotherapy regimens, particularly in patients with prior chemoradiotherapy...
  41. ncbi request reprint An analysis of alternative funding for physicians practicing gynecologic oncology in Ontario, Canada prior to 2001
    L Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Eur J Gynaecol Oncol 27:61-4. 2006
    ..To consider the policy issue of physician reimbursement by examining the events that preceded the Ontario Gynecologic Oncologists moving from a fee-for-service environment to an alternate payment plan in 2001...
  42. ncbi request reprint Phase II multicenter open-label study of carboplatin and pegylated liposomal doxorubicin in uterine and cervical malignancies
    L H Le
    Princess Margaret Hospital, Toronto, ON, Canada
    Int J Gynecol Cancer 15:799-806. 2005
    ..3%). There were no treatment-related deaths. The combination of carboplatin and PLD is well tolerated with sufficient activity to justify additional evaluation in clinical trials and might be suited to the addition of a taxane...
  43. doi request reprint End of life care for women with gynecologic cancers
    L Barbera
    Department of Radiation Oncology, University of Toronto, Ontario, Canada
    Gynecol Oncol 118:196-201. 2010
    ....
  44. ncbi request reprint Adjuvant radiotherapy in women with stage I endometrial cancer: a systematic review
    Himu Lukka
    Juravinski Regional Cancer Centre, Ontario, Canada
    Gynecol Oncol 102:361-8. 2006
    ..To review the literature regarding the role of adjuvant radiotherapy (RT) in women with stage I endometrial cancer in terms of survival and pelvic control...
  45. ncbi request reprint Intraperitoneal chemotherapy in the first-line treatment of women with stage III epithelial ovarian cancer: a systematic review with metaanalyses
    Laurie Elit
    Department of Obstetrics and Gynecology, Hamilton Regional Cancer Centre, Hamilton, Ontario, Canada
    Cancer 109:692-702. 2007
    ..Further research is needed concerning specific aspects of the treatment, such as optimal agent, dose, and scheduling...
  46. ncbi request reprint Weekly intravenous methotrexate with folinic acid for nonmetastatic gestational trophoblastic neoplasia
    J S Kwon
    Division of Gynecologic Oncology, University of Toronto, Toronto, Canada
    Gynecol Oncol 82:367-70. 2001
    ..Large randomized studies are required to determine the optimal treatment for nonmetastatic gestational trophoblastic neoplasia...
  47. doi request reprint Sorafenib in combination with gemcitabine in recurrent epithelial ovarian cancer: a study of the Princess Margaret Hospital Phase II Consortium
    Stephen A Welch
    Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    Int J Gynecol Cancer 20:787-93. 2010
    ..This phase 2 study was designed to examine the safety and efficacy of gemcitabine and sorafenib in patients with recurrent EOC...
  48. doi request reprint Secondary cancer prevention during follow-up for endometrial cancer
    Janice S Kwon
    Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada
    Obstet Gynecol 113:790-5. 2009
    ..To conduct a population-based study of incidence and screening rates for secondary breast and colorectal cancers after endometrial cancer and to assess implications for follow-up...
  49. doi request reprint Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCIC IND-148
    Amit M Oza
    Princess Margaret Hospital, University Health Network, Bras Family Drug Development Program, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 26:4319-25. 2008
    ..Epidermal growth factor receptor (EGFR) overexpression is common in endometrial cancers and may have a major role in tumor growth and progression. Erlotinib is an orally active, selective inhibitor of EGFR tyrosine kinase activity...
  50. pmc Follow-up for women after treatment for cervical cancer
    L Elit
    Juravinski Regional Cancer Centre, Hamilton, ON
    Curr Oncol 17:65-9. 2010
    ..What is the most appropriate follow-up strategy for patients with cervical cancer who are clinically disease-free after receiving primary treatment?..
  51. ncbi request reprint The quality of the operative report for women with ovarian cancer in Ontario
    Laurie Elit
    Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada
    J Obstet Gynaecol Can 28:892-7. 2006
    ..To assess the quality of the operative reports from cases of ovarian cancer surgery in Ontario...
  52. ncbi request reprint Follow-up after primary therapy for endometrial cancer: a systematic review
    Michael Fung-Kee-Fung
    Ottawa Regional Cancer Centre, Ontario, Canada
    Gynecol Oncol 101:520-9. 2006
    ..To determine the optimum follow-up of women who are clinically disease-free following potentially curative treatment for endometrial cancer...
  53. doi request reprint Prospective cost-effectiveness analysis of cetuximab in metastatic colorectal cancer: evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 trial
    Nicole Mittmann
    Health Outcomes and Pharmacoeconomics Research Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    J Natl Cancer Inst 101:1182-92. 2009
    ..17 study who received cetuximab plus best supportive care (N = 283) or best supportive care alone (N = 274)...
  54. ncbi request reprint A comparison of two prophylactic regimens for hypersensitivity reactions to paclitaxel
    Janice S Kwon
    Division of Gynecologic Oncology, University of Toronto, Toronto, Ontario, M5S 1A1, Canada
    Gynecol Oncol 84:420-5. 2002
    ....
  55. ncbi request reprint The rapid uptake of concurrent chemotherapy for cervix cancer patients treated with curative radiation
    Lisa Barbera
    Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 64:1389-94. 2006
    ..The purpose of this study is to examine the rate of chemotherapy use, in the province of Ontario, before and after these publications...
  56. ncbi request reprint Evaluation of postoperative pain control for women undergoing surgery for gynaecologic malignancies
    Laurie M Elit
    Department of Obstetrics and Gynaecology, McMaster University, Hamilton, Ontario, Canada
    J Obstet Gynaecol Can 26:1051-8. 2004
    ....