Philip J Devereaux

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. pmc Quality of care in for-profit and not-for-profit nursing homes: systematic review and meta-analysis
    Vikram R Comondore
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
    BMJ 339:b2732. 2009
  2. doi request reprint Revisiting sample size: are big trials the answer?
    Giovanna A L Lurati Buse
    Population Health Research Institute, Hamilton Health Sciences, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Bone Joint Surg Am 94:75-9. 2012
  3. pmc An international prospective cohort study evaluating major vascular complications among patients undergoing noncardiac surgery: the VISION Pilot Study
    P J Devereaux
    Population Health Research Institute, David Braley Cardiac, Vascular, and Stroke Research Institute, RoomC1 116, Perioperative Medicine and Surgical Research Unit, c o Hamilton General Hospital, 237 Barton Street East, Hamilton, ON, Canada, L8L2X2
    Open Med 5:e193-200. 2011
  4. pmc Beta 2 antagonism in acute respiratory failure
    Rob Mac Sweeney
    Regional Intensive Care Unit, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland
    Crit Care 14:1012. 2010
  5. pmc Detecting myocardial infarction in critical illness using screening troponin measurements and ECG recordings
    Wendy Lim
    Department of Medicine, McMaster University, Canada
    Crit Care 12:R36. 2008
  6. pmc Elevated troponin and myocardial infarction in the intensive care unit: a prospective study
    Wendy Lim
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Crit Care 9:R636-44. 2005
  7. pmc Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: a simulation study
    Rong Chu
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Sciences Centre, Room 2C7, 1200 Main Street West, Hamilton ON, L8N 3Z5, Canada
    BMC Med Res Methodol 11:21. 2011
  8. pmc Testing for heterogeneity among the components of a binary composite outcome in a clinical trial
    Janice Pogue
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Med Res Methodol 10:49. 2010
  9. pmc Values and preferences in oral anticoagulation in patients with atrial fibrillation, physicians' and patients' perspectives: protocol for a two-phase study
    Pablo Alonso-Coello
    Iberoamerican Cochrane Center, Hospital Sant Pau, Sant Antoni Maria Claret 171, Barcelona, Spain
    BMC Health Serv Res 8:221. 2008
  10. ncbi request reprint An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods
    P J Devereaux
    Department of Medicine, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Room 2C8, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    J Clin Epidemiol 57:1232-6. 2004

Detail Information

Publications88

  1. pmc Quality of care in for-profit and not-for-profit nursing homes: systematic review and meta-analysis
    Vikram R Comondore
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
    BMJ 339:b2732. 2009
    ..To compare quality of care in for-profit and not-for-profit nursing homes...
  2. doi request reprint Revisiting sample size: are big trials the answer?
    Giovanna A L Lurati Buse
    Population Health Research Institute, Hamilton Health Sciences, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Bone Joint Surg Am 94:75-9. 2012
    ..This paper reviews basic concepts and pitfalls in sample-size estimation and focuses on the importance of large trials in the generation of valid evidence...
  3. pmc An international prospective cohort study evaluating major vascular complications among patients undergoing noncardiac surgery: the VISION Pilot Study
    P J Devereaux
    Population Health Research Institute, David Braley Cardiac, Vascular, and Stroke Research Institute, RoomC1 116, Perioperative Medicine and Surgical Research Unit, c o Hamilton General Hospital, 237 Barton Street East, Hamilton, ON, Canada, L8L2X2
    Open Med 5:e193-200. 2011
    ....
  4. pmc Beta 2 antagonism in acute respiratory failure
    Rob Mac Sweeney
    Regional Intensive Care Unit, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland
    Crit Care 14:1012. 2010
    ..Although this evidence is encouraging, there is a need for a phase 2 proof-of-concept randomized controlled trial of beta-blocker therapy in patients admitted with acute respiratory failure...
  5. pmc Detecting myocardial infarction in critical illness using screening troponin measurements and ECG recordings
    Wendy Lim
    Department of Medicine, McMaster University, Canada
    Crit Care 12:R36. 2008
    ..This is a prospective screening study...
  6. pmc Elevated troponin and myocardial infarction in the intensive care unit: a prospective study
    Wendy Lim
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Crit Care 9:R636-44. 2005
    ....
  7. pmc Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: a simulation study
    Rong Chu
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Sciences Centre, Room 2C7, 1200 Main Street West, Hamilton ON, L8N 3Z5, Canada
    BMC Med Res Methodol 11:21. 2011
    ..Our objective was to investigate the properties of commonly used statistical models at various levels of clustering in the context of multicentre RCTs...
  8. pmc Testing for heterogeneity among the components of a binary composite outcome in a clinical trial
    Janice Pogue
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Med Res Methodol 10:49. 2010
    ..This paper compares the power of different tests to detect heterogeneity of treatment effect across components of a composite binary outcome...
  9. pmc Values and preferences in oral anticoagulation in patients with atrial fibrillation, physicians' and patients' perspectives: protocol for a two-phase study
    Pablo Alonso-Coello
    Iberoamerican Cochrane Center, Hospital Sant Pau, Sant Antoni Maria Claret 171, Barcelona, Spain
    BMC Health Serv Res 8:221. 2008
    ..The literature postulates that patient and clinician preferences may explain this low utilization...
  10. ncbi request reprint An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods
    P J Devereaux
    Department of Medicine, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Room 2C8, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    J Clin Epidemiol 57:1232-6. 2004
    ..We undertook an observational study to determine whether concealment of randomization or blinding was used in RCTs that failed to report these bias-reducing strategies...
  11. pmc How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    BMJ 331:313-21. 2005
    ..To determine the effect of perioperative beta blocker treatment in patients having non-cardiac surgery...
  12. pmc Perioperative cardiac events in patients undergoing noncardiac surgery: a review of the magnitude of the problem, the pathophysiology of the events and methods to estimate and communicate risk
    P J Devereaux
    Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ont
    CMAJ 173:627-34. 2005
    ....
  13. pmc Are the recommendations to use perioperative beta-blocker therapy in patients undergoing noncardiac surgery based on reliable evidence?
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, Ont
    CMAJ 171:245-7. 2004
  14. pmc Need for expertise based randomised controlled trials
    P J Devereaux
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street, West Hamilton ON, Canada L8N 3Z5
    BMJ 330:88. 2005
  15. pmc Surveillance and prevention of major perioperative ischemic cardiac events in patients undergoing noncardiac surgery: a review
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, Ont
    CMAJ 173:779-88. 2005
    ..The best evidence does not support a management strategy of preoperative coronary revascularization before noncardiac surgery...
  16. ncbi request reprint Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial
    P J Devereaux
    McMaster University, Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, Room 2C8, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Lancet 371:1839-47. 2008
    ..This randomised controlled trial, done in 190 hospitals in 23 countries, was designed to investigate the effects of perioperative beta blockers...
  17. ncbi request reprint A survey evaluating surgeons' peri-operative usage of acetyl-salicylic acid (ASA) and their willingness to enroll their patients in a perioperative ASA randomized controlled trial
    Rajesh Hiralal
    McMaster University Health Sciences Centre, 1200 Main Street West, Hamilton, Ontario, Canada
    Clin Invest Med 33:E375-83. 2010
    ..The objective of this study was to determine surgeons' perioperative usage of ASA, and if they would enroll their patients in a perioperative ASA randomized controlled trial (RCT)...
  18. ncbi request reprint Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) trial: a randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery
    P J Devereaux
    Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    Am Heart J 152:223-30. 2006
    ..We have initiated the POISE trial to definitively establish the effects of beta-blocker therapy in patients undergoing noncardiac surgery...
  19. ncbi request reprint The reporting of methodological factors in randomized controlled trials and the association with a journal policy to promote adherence to the Consolidated Standards of Reporting Trials (CONSORT) checklist
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Control Clin Trials 23:380-8. 2002
    ..Until these inadequacies are resolved health-care providers will remain limited in their ability to make informed inferences about the validity of the studies upon which they base their clinical practice...
  20. ncbi request reprint The evolution of the randomized controlled trial and its role in evidence-based decision making
    P J Devereaux
    Department of Medicine and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    J Intern Med 254:105-13. 2003
    ..We discuss the role of the randomized controlled trial within evidence-based decision making...
  21. pmc A systematic review and meta-analysis of studies comparing mortality rates of private for-profit and private not-for-profit hospitals
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, Ont
    CMAJ 166:1399-406. 2002
    ..To inform this debate, we undertook a systematic review and meta-analysis of studies comparing the mortality rates of private for-profit hospitals and those of private not-for-profit hospitals...
  22. pmc Differences between perspectives of physicians and patients on anticoagulation in patients with atrial fibrillation: observational study
    P J Devereaux
    Department of Medicine, Dalhousie University, Halifax, Nova Scotia, B3K 6A3, Canada
    BMJ 323:1218-22. 2001
    ..Design: Prospective observational study...
  23. ncbi request reprint Comparison of mortality between private for-profit and private not-for-profit hemodialysis centers: a systematic review and meta-analysis
    P J Devereaux
    Depatment of Medicine, McMaster University, Faculty of Health Sciences, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 288:2449-57. 2002
    ..There has been extensive debate about whether the profit status of these facilities influences patient mortality...
  24. ncbi request reprint Physician interpretations and textbook definitions of blinding terminology in randomized controlled trials
    P J Devereaux
    Department of Medicine, McMaster University, 1200 Main St W, Room 2C12, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 285:2000-3. 2001
    ..The terminology authors often use to convey blinding status (single, double, and triple blinding) may be open to various interpretations...
  25. pmc Reviewing the reviewers: the quality of reporting in three secondary journals
    P J Devereaux
    Department of Medicine, Dalhousie University, Halifax, NS
    CMAJ 164:1573-6. 2001
    ..However, for clinicians to evaluate the validity and applicability of new findings, they need information on the study design, methodology and results...
  26. ncbi request reprint Natural health product-drug interactions: a systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ther Drug Monit 27:549-57. 2005
    ..With the exception of St. John wort, clinicians and the public do not have information that permits strong inferences about interactions between NHPs and conventional medications...
  27. pmc Optimal method of coronary revascularization in patients receiving dialysis: systematic review
    Immaculate F Nevis
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Clin J Am Soc Nephrol 4:369-78. 2009
    ..Patients receiving dialysis have a high burden of cardiovascular disease. Some receive coronary artery revascularization but the optimal method is controversial...
  28. ncbi request reprint Etiology of troponin elevation in critically ill patients
    Wendy Lim
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada L8N 3Z5
    J Crit Care 25:322-8. 2010
    ..The aim of this study was to assess the etiology of cardiac troponin elevation among patients admitted to the intensive care unit (ICU) and to examine whether etiology affects mortality and length of stay...
  29. pmc The number of patients and events required to limit the risk of overestimation of intervention effects in meta-analysis--a simulation study
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada
    PLoS ONE 6:e25491. 2011
    ..It has been suggested that surpassing the optimal information size (i.e., the required meta-analysis sample size) provides sufficient protection against overestimation due to random error, but this claim has not yet been validated...
  30. doi request reprint Rationale and design of the coronary artery bypass grafting surgery off or on pump revascularization study: a large international randomized trial in cardiac surgery
    Andre Lamy
    Population Health Research Institute, Hamilton Health Sciences, McMaster University, Canada
    Am Heart J 163:1-6. 2012
    ..Prior trials had few events and relatively short follow-up. There is a need for a large randomized, controlled trial with long-term follow-up to inform both the short- and long-term impact of the 2 approaches to CABG...
  31. ncbi request reprint Perceptions of authors' contributions are influenced by both byline order and designation of corresponding author
    Mohit Bhandari
    Division of Orthopedic Surgery, Department of Surgery, CLARITY Research Group, McMaster University, 293 Wellington Street North, Suite 110, Hamilton, Ontario L8L 8E7, Canada Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main St W, Hamilton, Ontario L8S 4K1, Canada Electronic address
    J Clin Epidemiol 67:1049-54. 2014
    ..We explored how readers interpret authors' roles based on authorship order and corresponding author...
  32. ncbi request reprint Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension
    Michael Walsh
    Departments of Medicine, and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Anesthesiology 119:507-15. 2013
    ..The authors evaluated the association between the intraoperative mean arterial pressure (MAP) and the risk of AKI and myocardial injury...
  33. pmc Secular trends in acute dialysis after elective major surgery--1995 to 2009
    Nausheen F Siddiqui
    Department of Medicine, Western University, London, Ontario
    CMAJ 184:1237-45. 2012
    ..Acute dialysis is used to support life in the most severe cases. We examined whether rates and outcomes of acute dialysis after elective major surgery have changed over time...
  34. ncbi request reprint Incidence and timing of myocardial infarction after total joint arthroplasty
    Rajiv Gandhi
    Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    J Arthroplasty 21:874-7. 2006
    ..Our data cautions against hospital discharge within 3 days of surgery...
  35. pmc Open versus endovascular repair of abdominal aortic aneurysm: a survey of Canadian vascular surgeons
    Tara M Mastracci
    Department of Surgery, McMaster University, Hamilton, Ontario, Canada
    Can J Surg 51:142-8; quiz 149. 2008
    ....
  36. pmc Association between angiotensin converting enzyme inhibitor or angiotensin receptor blocker use prior to major elective surgery and the risk of acute dialysis
    Mitesh Shah
    Division of Nephrology, Department of Medicine, Western University, London, Canada
    BMC Nephrol 15:53. 2014
    ..Some studies but not others suggest angiotensin converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB) use prior to major surgery associates with a higher risk of postoperative acute kidney injury (AKI) and death...
  37. pmc Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group
    Lehana Thabane
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada
    Trials 12:48. 2011
    ..The ultimate goal is to enhance global health by contributing to efforts to reduce the burden of CVD and DM...
  38. ncbi request reprint Kidney disease after preeclampsia: a systematic review and meta-analysis
    Sarah D McDonald
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Kidney Dis 55:1026-39. 2010
    ..Our objective is to undertake a systematic review and meta-analysis to determine whether women with a history of preeclampsia are at increased risk of subsequent kidney disease...
  39. ncbi request reprint Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
    Edward Mills
    Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Eur J Clin Pharmacol 61:1-7. 2005
    ..To determine whether ingestion of milk thistle affects the pharmacokinetics of indinavir...
  40. doi request reprint Cognitive dysfunction in hip fracture patients
    Harman Chaudhry
    Division of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada
    Orthop Clin North Am 44:153-62. 2013
    ..This article provides an overview of the currently available evidence regarding cognitive dysfunction, specifically dementia and delirium, in patients with hip fractures...
  41. doi request reprint Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Am Coll Cardiol 52:1769-81. 2008
    ..This study aimed to evaluate the effectiveness of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) in primary prevention of cardiovascular events...
  42. ncbi request reprint Doubling the impact: publication of systematic review articles in orthopaedic journals
    Mohit Bhandari
    Health Information Research Unit, McMaster University, Hamilton, Ontario, Canada
    J Bone Joint Surg Am 86:1012-6. 2004
    ....
  43. ncbi request reprint Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analyses
    Sarah D McDonald
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, McMaster University, Hamilton, Canada
    Am Heart J 156:918-30. 2008
    ..05% to 0.93%, but their subsequent cardiovascular sequelae are unclear. The aim of this study was to determine if women with a history of preeclampsia/eclampsia are at increased risk of long-term cardiovascular sequelae...
  44. pmc Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol
    Darong Wu
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    Trials 15:33. 2014
    ..Until now, no convincing data exists addressing the impact of DUR on participation rates in trials. The objective of this study is to evaluate the epidemiology and to explore factors associated with DUR...
  45. doi request reprint Sensible guidelines for the conduct of large randomized trials
    Salim Yusuf
    Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada
    Clin Trials 5:38-9. 2008
  46. doi request reprint Biomarkers for predicting serious cardiac outcomes at 72 hours in patients presenting early after chest pain onset with symptoms of acute coronary syndromes
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University, and Hamilton Regional Laboratory Medicine Program, Juravinski Hospital and Cancer Centre, Hamilton, Ontario, Canada
    Clin Chem 58:298-302. 2012
    ..We investigated the performance of 9 biomarkers for an early serious outcome...
  47. pmc Interaction of St John's wort with conventional drugs: systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 329:27-30. 2004
    ..To determine the methodological quality of clinical trials that examined possible interactions of St John's wort with conventional drugs, and to examine the results of these trials...
  48. ncbi request reprint Methodology of neuropsychological research in multicentre randomized clinical trials: a model derived from the International Subarachnoid Aneurysm Trial
    Richard B Scott
    Russell Cairns Unit, The Radcliffe Infirmary, Oxford Radcliffe Hospitals NHS Trust, Oxford, Oxfordshire, UK
    Clin Trials 1:31-9. 2004
    ..Extrapolations from the observations and calculations reported here can be employed as an evidence base to inform the design of neuropsychological outcome studies in large multicentre trials...
  49. ncbi request reprint Abstracts presented at the American Society of Clinical Oncology conference: how completely are trials reported?
    Sally Hopewell
    UK Cochrane Centre, Oxford, UK
    Clin Trials 2:265-8. 2005
    ..To assess how completely trials published in conference proceedings are reported and whether this has changed over time...
  50. pmc Bad reporting does not mean bad methods for randomised trials: observational study of randomised controlled trials performed by the Radiation Therapy Oncology Group
    Heloisa P Soares
    Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
    BMJ 328:22-4. 2004
    ..To determine whether poor reporting of methods in randomised controlled trials reflects on poor methods...
  51. ncbi request reprint The typical Cochrane review. How many trials? How many participants?
    Susan Mallett
    Int J Technol Assess Health Care 18:820-3. 2002
    ..To describe the number of trials and participants in a typical systematic review from The Cochrane Database of Systematic Reviews...
  52. ncbi request reprint Discussion sections in reports of controlled trials published in general medical journals
    Mike Clarke
    UK Cochrane Centre, National Health Service Research and Development Programme, Summertown Pavilion, Middle Way, Oxford OX2 7LG, England
    JAMA 287:2799-801. 2002
    ..We assessed the extent to which reports of controlled trials published in the same 5 journals discussed new results in light of the totality of evidence from other controlled trials...
  53. ncbi request reprint How useful are Cochrane reviews in identifying research needs?
    Lorcan Clarke
    UK Cochrane Centre, NHS R and D Programme, Oxford, UK
    J Health Serv Res Policy 12:101-3. 2007
    ..To determine the extent to which reports of Cochrane reviews recommend the need for further research and, if so, the extent to which they make suggestions regarding that research...
  54. pmc Reports of clinical trials should begin and end with up-to-date systematic reviews of other relevant evidence: a status report
    Mike Clarke
    UK Cochrane Centre, NHS R and D Programme, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    J R Soc Med 100:187-90. 2007
    ..In the current study, we assess whether there had been progress in this respect in 2005 and also investigate the extent to which reports begin by referring to systematic reviews providing the justification for the new research reported...
  55. ncbi request reprint Systematic reviews of surgical interventions
    Martin Burton
    Department of Otolaryngology Head and Neck Surgery, University of Oxford, The Radcliffe Infirmary, Oxford OX2 6HE, England, UK
    Surg Clin North Am 86:101-14, ix. 2006
    ..They should be a prerequisite of any new research, a key component in decision making, and an opportunity for all surgical practitioners to get involved in the conduct and interpretation of research...
  56. ncbi request reprint The importance of preservation of the ethical principle of equipoise in the design of clinical trials: relative impact of the methodological quality domains on the treatment effect in randomized controlled trials
    Benjamin Djulbegovic
    Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Dr, Tampa, FL 33612, USA
    Account Res 10:301-15. 2003
    ..We argue that an adequate control intervention can be selected if people designing a trial explicitly take into consideration the ethical principle of equipoise, also known as "the uncertainty principle."..
  57. ncbi request reprint Commentary: the 1944 patulin trial: the first properly controlled multicentre trial conducted under the aegis of the British Medical Research Council
    Iain Chalmers
    James Lind Library, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Int J Epidemiol 33:253-60. 2004
    ..This status is reflected in the International Journal of Epidemiology's reproduction of the full text of the trial report in this issue of the journal...
  58. ncbi request reprint How many do I need? Basic principles of sample size estimation
    Declan Devane
    School of Nursing and Midwifery Studies, University of Dublin Trinity College, Dublin, Ireland
    J Adv Nurs 47:297-302. 2004
    ..Nevertheless, this aspect of research design often causes confusion for the novice researcher...
  59. ncbi request reprint Reporting of trials presented in conference abstracts needs to be improved
    Sally Hopewell
    UK Cochrane Centre, Summertown Pavilion, Middle Way, Oxford OX2 7LB, UK
    J Clin Epidemiol 59:681-4. 2006
    ..To assess how trial information reported in conference abstracts differs to their subsequent full publication...
  60. ncbi request reprint How many Cochrane reviews are needed to cover existing evidence on the effects of health care interventions?
    Susan Mallett
    UK Cochrane Centre, Oxford, England, UK
    ACP J Club 139:A11. 2003
  61. ncbi request reprint Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening records
    Phil Edwards
    Public Health Intervention Research Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, 49 51 Bedford Square, London WC1B 3DP, UK
    Stat Med 21:1635-40. 2002
    ..Two reviewers should screen records for eligibility, whenever possible, in order to maximize ascertainment of relevant trials...
  62. pmc Increasing response rates to postal questionnaires: systematic review
    Phil Edwards
    CRASH Trial Co ordinating Centre, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1B 1DP
    BMJ 324:1183. 2002
    ..To identify methods to increase response to postal questionnaires...
  63. ncbi request reprint Number and size of randomized trials reported in general health care journals from 1948 to 1997
    Steve McDonald
    UK Cochrane Centre, NHS Research and Development Programme, Oxford OX2 7LG, UK
    Int J Epidemiol 31:125-7. 2002
    ..Randomized trials are important for controlling selection biases, and where sufficient numbers of participants are involved, have the potential to yield reliable estimates of treatment effects...
  64. ncbi request reprint Commentary: searching for trials for systematic reviews: what difference does it make?
    Mike Clarke
    UK Cochrane Centre, NHS R and D Programme, Summertown Pavilion, Middle Way Oxford OX2 7LG, UK
    Int J Epidemiol 31:123-4. 2002
  65. ncbi request reprint The Cochrane Collaboration: providing and obtaining the best evidence about the effects of health care
    Mike Clarke
    U K Cochrane Centre
    Eval Health Prof 25:8-11. 2002
  66. pmc Balancing benefits and harms in health care
    Luis Gabriel Cuervo
    BMJ 327:65-6. 2003
  67. pmc Doing new research? Don't forget the old
    Mike Clarke
    United Kingdom Cochrane Centre, Oxford, United Kingdom
    PLoS Med 1:e35. 2004
  68. pmc A call for systematic reviews
    Victor M Montori
    J Gen Intern Med 19:1240-1. 2004
  69. ncbi request reprint "No language restrictions" in database searches: what does this really mean?
    Karen Pilkington
    Research Council for Complementary Medicine, London, UK
    J Altern Complement Med 11:205-7. 2005
    ..Searching that relies only on English language databases may result in failure to find many relevant studies published in languages other than English, irrespective of the research question and the avoidance of any language restrictions...
  70. ncbi request reprint Involvement of the consumer voice
    Hazel Thornton
    Health Expect 9:92-3; author reply 93. 2006
  71. pmc Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group
    Ambuj Kumar
    Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
    BMJ 331:1295. 2005
    ....
  72. pmc How to formulate research recommendations
    Polly Brown
    BMJ Publishing Group, London WC1H 9JR
    BMJ 333:804-6. 2006
  73. ncbi request reprint Evaluating maternity care: a core set of outcome measures
    Declan Devane
    School of Nursing and Midwifery, Trinty College Dublin, Dublin, Ireland
    Birth 34:164-72. 2007
    ..We sought to identify a minimum set of outcome measures for evaluating models of maternity care from the perspective of key stakeholders...
  74. ncbi request reprint The sensitivity and precision of search terms in Phases I, II and III of the Cochrane Highly Sensitive Search Strategy for identifying reports of randomized trials in medline in a specific area of health care--HIV/AIDS prevention and treatment interventio
    Anne Eisinga
    UK Cochrane Centre, Summertown Pavilion, Middle Way, Oxford, UK
    Health Info Libr J 24:103-9. 2007
    ..To detect term(s) in the Cochrane Highly Sensitive Search Strategy (HSSS) that retain high sensitivity but improve precision in retrieving reports of trials in the PubMed version of medline...
  75. ncbi request reprint STROBE: new standards for reporting observational epidemiology, a chance to improve
    Shah Ebrahim
    Int J Epidemiol 36:946-8. 2007
  76. ncbi request reprint The Cochrane Collaboration and the Cochrane Library
    Mike Clarke
    UK Cochrane Centre, NHS R and D Programme, Oxford, England
    Otolaryngol Head Neck Surg 137:S52-4. 2007
    ..I review the origins, development, and structure of the organization and describe the important components of its output, The Cochrane Library...
  77. pmc Yes Sir, no Sir, not much difference Sir
    Mike Clarke
    School of Nursing and Midwifery, Trinity College Dublin, 24 D Olier Street, Dublin 2, Ireland
    J R Soc Med 100:571-2. 2007
    ..To assess whether making the sender's knighthood explicit in a series of letters would have any detectable effect on the response...
  78. pmc CONSORT for reporting randomized controlled trials in journal and conference abstracts: explanation and elaboration
    Sally Hopewell
    UK Cochrane Centre, Oxford, United Kingdom
    PLoS Med 5:e20. 2008
    ..Here, we extend the CONSORT (Consolidated Standards of Reporting Trials) Statement to develop a minimum list of essential items, which authors should consider when reporting the results of a RCT in any journal or conference abstract...
  79. doi request reprint CONSORT for reporting randomised trials in journal and conference abstracts
    Sally Hopewell
    UK Cochrane Centre, Summertown Pavilion, Oxford OX2 7LG, UK
    Lancet 371:281-3. 2008
  80. ncbi request reprint International activity in the Cochrane Collaboration with particular reference to India
    Claire Allen
    The Cochrane Collaboration Secretariat, Oxford, United Kingdom
    Natl Med J India 20:250-5. 2007
    ..The continued growth of contributors from India and South Asia will help ensure that decisions regarding healthcare in the region are informed by reliable and relevant evidence...
  81. pmc Chlorpromazine for schizophrenia: a Cochrane systematic review of 50 years of randomised controlled trials
    Clive Elliott Adams
    Cochrane Schizophrenia Group, Academic Department of Psychiatry and Behavioural Sciences, University of Leeds, Leeds, LS2 9LT, UK
    BMC Med 3:15. 2005
    ..Quantitative reviews are rare; this one evaluates the effects of chlorpromazine in the treatment of schizophrenia in comparison with placebo...
  82. doi request reprint Reporting of adverse events in systematic reviews can be improved: survey results
    Sally Hopewell
    UK Cochrane Centre, Oxford OX2 7LG, UK
    J Clin Epidemiol 61:597-602. 2008
    ..To assess how information about adverse events is included in systematic reviews...
  83. pmc Randomised controlled trials in Africa of HIV and AIDS: descriptive study and spatial distribution
    Nandi Siegfried
    UK Cochrane Centre, Oxford OX2 7LG
    BMJ 331:742. 2005
    ..To identify and describe randomised controlled trials on HIV and AIDS conducted in Africa and to map their spatial distribution using exact geographic coordinates...
  84. ncbi request reprint A prospective evaluation of the outcome after small saphenous varicose vein surgery with one-year follow-up
    John L O'Hare
    Department of Vascular Surgery, Gloucestershire Royal Hospital, Gloucester, United Kingdom
    J Vasc Surg 48:669-73; discussion 674. 2008
    ..The aim was to examine the effect of various surgical maneuvers during standard surgery for small saphenous varicose veins (SSV)...
  85. pmc How the Cochrane collaboration is responding to the Asian tsunami
    Prathap Tharyan
    Christian Medical College, Vellore, Tamil Nadu, India
    PLoS Med 2:e169. 2005
  86. pmc Is evidence-based medicine relevant to the developing world?
    Paul Chinnock
    Cochrane Injuries Group, London, United Kingdom
    PLoS Med 2:e107. 2005
  87. ncbi request reprint Cancer treatment reviews welcomes submission of the Cochrane Reviews
    Nicholas Pavlidis
    Cancer Treat Rev 32:243-4. 2006