Research Topics
| Gerard CoxSummaryAffiliation: McMaster University Country: Canada Publications
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Detail Information
Publications
Long-term (5 year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trialNeil C Thomson
Gartnavel General Hospital, University of Glasgow, Glasgow, UK
BMC Pulm Med 11:8. 2011..Bronchial thermoplasty (BT) is a bronchoscopic procedure that improves asthma control by reducing excess airway smooth muscle. Treated patients have been followed out to 5 years to evaluate long-term safety of this procedure...
Bronchial thermoplasty for severe asthmaGerard Cox
Firestone Institute for Respiratory Health, St Joseph s Healthcare, Hamilton, Ontario, Canada
Curr Opin Pulm Med 17:34-8. 2011..the present article will address the potential for bronchial thermoplasty to be used in addition to conventional medications to help us treat our patients with severe asthma...
Asthma control during the year after bronchial thermoplastyGerard Cox
St Joseph s Healthcare, McMaster University, Hamilton, ON, Canada
N Engl J Med 356:1327-37. 2007..Bronchial thermoplasty is a bronchoscopic procedure to reduce the mass of airway smooth muscle and attenuate bronchoconstriction. We examined the effect of bronchial thermoplasty on the control of moderate or severe persistent asthma...
New interventions in asthma including bronchial thermoplastyGerard Cox
McMaster University, Ontario, Hamilton, Canada
Curr Opin Pulm Med 14:77-81. 2008..The challenges of identifying which treatment would best help an individual patient can be addressed by use of noninvasive measurements to define their asthma...
Bronchial thermoplasty for asthmaGerard Cox
M B, Firestone Institute for Respiratory Health T2123, St Joseph s Healthcare, 50 Charlton Avenue, East Hamilton, ON L8N 4A6, Canada
Am J Respir Crit Care Med 173:965-9. 2006..Bronchial thermoplasty (BT) reduces the potential for smooth muscle-mediated bronchoconstriction by reducing the mass of smooth muscle in the walls of conducting airways...
Bronchial thermoplastyGerard Cox
Firestone Institute for Respiratory Health, St Joseph s Healthcare Hamilton, 50 Charlton Avenue E, Hamilton, ON L8N 4A6, Canada
Clin Chest Med 31:135-40,Table of Contents. 2010....
A prospective feasibility study of bronchial thermoplasty in the human airwayJohn D Miller
Division of Thoracic Surgery, St Joseph s Healthcare, 50 Charlton Ave East, Hamilton, ON, Canada L8N 4A6
Chest 127:1999-2006. 2005..Experience with animal studies has enabled development of appropriate reliable equipment, definition of therapeutic parameters, and descriptions of tissue effects of treatment...
Erratum to: unexpectedly low pulse oximetry measurements associated with variant hemoglobins: a systematic reviewMadeleine Verhovsek
Section of Hematology and Oncology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Hematol 86:722-5. 2011..The correct diagnosis will help to spare patients from unnecessary investigations and anxiety...
Effect of air filtration systems on asthma: a systematic review of randomized trialsEllen McDonald
Departments of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
Chest 122:1535-42. 2002..To systematically review the evidence of randomized trials evaluating the effects of residential air filtration systems on patients with asthma...
Unexpectedly low pulse oximetry measurements associated with variant hemoglobins: a systematic reviewMadeleine Verhovsek
Section of Hematology and Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
Am J Hematol 85:882-5. 2010..The correct diagnosis will help to spare patients from unnecessary investigations and anxiety...
Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjectsAsma Yaghi
Department of Medicine, McMaster University, Hamilton, ON, Canada
Respir Med 106:1139-47. 2012..Pharmacologic agents with different mechanisms of action can increase CBF of COPD cilia. Further investigation of the signalling pathways influencing CBF of COPD cilia is needed...
Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segmentsJeremy Mark Hernandez
Firestone Institute for Respiratory Health, St Joseph s Hospital, Room L 314, 50 Charlton Avenue East, Hamilton, ON, Canada L8N4A6
J Pharmacol Exp Ther 327:503-10. 2008....
Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trialShawn D Aaron
The Ottawa Health Research Institute and University of Ottawa, Ottawa, Ontario, Canada
Ann Intern Med 146:545-55. 2007..Treatment of moderate or severe chronic obstructive pulmonary disease (COPD) with combinations of inhaled corticosteroids, long-acting beta-agonists, and long-acting anticholinergic bronchodilators is common but unstudied...
Lung volume reduction surgery vs medical treatment: for patients with advanced emphysemaJohn D Miller
McMaster University, Hamilton Ontarion, Canada
Chest 127:1166-77. 2005..CONCLUSION: Six months after randomization, LVRS produced better palliation than optimal medical therapy in patients with advanced emphysema...
Cysteinyl leukotrienes promote human airway smooth muscle migrationKrishnan Parameswaran
Asthma Research Group, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, and Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Am J Respir Crit Care Med 166:738-42. 2002..The phosphatidylinositol-3 kinase pathway is a key signaling mechanism in the chemotactic migration of ASM cells in response to cysteinyl leukotrienes...
Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthmaIan D Pavord
Glenfield General Hospital, University Hospitals of Leicester NHS Trust, Groby Road, Leicester LE3 9QP, United Kingdom
Am J Respir Crit Care Med 176:1185-91. 2007..Bronchial thermoplasty (BT) is designed to reduce airway smooth muscle and improve asthma control...
