Research Topics
| Melissa C BrouwersSummaryAffiliation: McMaster University Country: Canada Publications
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Detail Information
Publications
Comparative effectiveness research paradigm: implications for systematic reviews and clinical practice guidelinesMelissa C Brouwers
Department of Oncology, McMaster University, Hamilton, ON, Canada L8S 4K1
J Clin Oncol 30:4202-7. 2012....
Core competencies in the science and practice of knowledge translation: description of a Canadian strategic training initiativeSharon E Straus
Li Ka Shing Knowledge Institute, St Michael s Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada
Implement Sci 6:127. 2011..This challenge has resulted in the development of implementation science or knowledge translation (KT) and the resulting need to build capacity in both the science and practice of KT...
The Global Rating Scale complements the AGREE II in advancing the quality of practice guidelinesMelissa C Brouwers
McMaster University, Department of Oncology, Hamilton, Ontario, Canada
J Clin Epidemiol 65:526-34. 2012..To explore the role of a four-item Global Rating Scale (GRS) that could be used in place of the Appraisal of Guidelines, Research and Evaluation II (AGREE II)...
The landscape of knowledge translation interventions in cancer control: what do we know and where to next? A review of systematic reviewsMelissa C Brouwers
McMaster University, Department of Oncology, Hamilton, Ontario, Canada
Implement Sci 6:130. 2011..We conducted a review of systematic reviews to better understand the evidentiary base of implementation strategies in cancer control...
Diffusion and dissemination of evidence-based dietary strategies for the prevention of cancerDonna Ciliska
School of Nursing, McMaster University, 1200 Main St W Hamilton, Ontario, L8N 3Z5, Canada
Nutr J 4:13. 2005..The purpose was to determine what strategies have been evaluated to disseminate cancer control interventions that promote the uptake of adult healthy diet?..
An exploration of how guideline developer capacity and guideline implementability influence implementation and adoption: study protocolAnna R Gagliardi
Toronto General Research Institute, 200 Elizabeth Street, 13EN 235, Toronto, Ontario, M5G2C4, Canada
Implement Sci 4:36. 2009..If successful, then long-term objective outcomes reflecting the adoption of processes and associated patient care outcomes could be evaluated...
Developing a decision aid to guide public sector health policy decisions: A study protocolPeggy Tso
Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
Implement Sci 6:46. 2011..The intent is not to develop a decision aid that will yield uniform recommendations across jurisdictions, but rather to facilitate more transparent policy decisions that reflect a balanced consideration of all relevant factors...
Protocol: developing a conceptual framework of patient mediated knowledge translation, systematic review using a realist approachAnna R Gagliardi
Departments of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
Implement Sci 6:25. 2011..The purpose of this knowledge synthesis is to develop a conceptual framework for patient-mediated KT interventions...
Many quality measurements, but few quality measures assessing the quality of breast cancer care in women: a systematic reviewHoward M Schachter
Children s Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON, Canada
BMC Cancer 6:291. 2006..Quality measurement is essential to monitor effectiveness and to guide improvements in healthcare...
Development of the AGREE II, part 1: performance, usefulness and areas for improvementMelissa C Brouwers
McMaster University, Program in Evidence based Care, Cancer Care Ontario, ON, Canada
CMAJ 182:1045-52. 2010..We tested a new seven-point scale, evaluated the usefulness of the original items in the instrument, investigated evidence to support shorter, tailored versions of the tool, and identified areas for improvement...
Inventory of Cancer Guidelines: a tool to advance the guideline enterprise and improve the uptake of evidenceMelissa C Brouwers
Department of Oncology and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Expert Rev Pharmacoecon Outcomes Res 11:151-61. 2011....
E-learning interventions are comparable to user's manual in a randomized trial of training strategies for the AGREE IIMelissa C Brouwers
Department of Oncology, McMaster University, Hamilton, Ontario, Canada
Implement Sci 6:81. 2011..abstract:..
What implementation interventions increase cancer screening rates? a systematic reviewMelissa C Brouwers
Program in Evidence based Care, Cancer Care Ontario, Hamilton, Ontario, Canada
Implement Sci 6:111. 2011..abstract:..
Effective interventions to facilitate the uptake of breast, cervical and colorectal cancer screening: an implementation guidelineMelissa C Brouwers
Program in Evidence based Care, Cancer Care Ontario, Hamilton, Ont, Canada
Implement Sci 6:112. 2011..We developed an implementation guideline to answer the question: What interventions have been shown to increase the uptake of cancer screening by individuals, specifically for breast, cervical, and colorectal cancers?..
Development of the AGREE II, part 2: assessment of validity of items and tools to support applicationMelissa C Brouwers
McMaster University, Cancer Care Ontario, Hamilton, Ont, Canada
CMAJ 182:E472-8. 2010..We established a program of research to improve the development, reporting and evaluation of practice guidelines. We assessed the construct validity of the items and user's manual in the beta version of the AGREE II...
Can surveying practitioners about their practices help identify priority clinical practice guideline topics?Melissa C Brouwers
Program in Evidence based Care, Cancer Care Ontario, Hamilton, Ontario, Canada
BMC Health Serv Res 3:23. 2003..In order to establish which guideline topics are priorities, practitioners were surveyed regarding their current practice...
Clinicians' assessments of practice guidelines in oncology: the CAPGO surveyMelissa C Brouwers
Cancer Care Ontario, Hamilton, Canada
Int J Technol Assess Health Care 20:421-6. 2004..Our objective is to report on the development and refinement of an instrument designed to measure oncologists' assessments of guidelines in oncology...
Evaluating the role of quality assessment of primary studies in systematic reviews of cancer practice guidelinesMelissa C Brouwers
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
BMC Med Res Methodol 5:8. 2005..The purpose of this study was to evaluate the role of study quality assessment of primary studies in cancer practice guidelines...
Clinicians' evaluations of, endorsements of, and intentions to use practice guidelines change over time: a retrospective analysis from an organized guideline programMelissa Brouwers
Departments of Oncology and Clinical Epidemiology and Biostatistics, McMaster University and Program in Evidence based Care, Cancer Care Ontario, Hamilton, Ontario, Canada
Implement Sci 4:34. 2009..Continued engagement of clinicians least receptive to CPGs may be worthwhile because they are the ones showing most significant gains in CPG quality ratings, endorsement ratings, and intentions to use in practice ratings...
A randomized trial to evaluate e-learning interventions designed to improve learner's performance, satisfaction, and self-efficacy with the AGREE IIMelissa C Brouwers
McMaster University, Department of Oncology and Department of Clinical Epidemiology, McMaster University, Hamilton, Ontario, Canada
Implement Sci 5:29. 2010..The results will facilitate international capacity to apply the AGREE II accurately and with confidence and to enhance the overall guideline enterprise...
The Completeness of Reporting (CORE) index identifies important deficiencies in observational study conference abstractsMichelle E Kho
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
J Clin Epidemiol 61:1241-9. 2008..The aim was to develop, test, and apply an index to assess the completeness of reporting in a cohort of observational studies of conference abstracts...
Recruitment of multiple stakeholders to health services research: lessons from the front linesMichelle E Kho
Department of Clinical Epidemiology and Biostatistics, McMaster University, Henderson Site, 60 G Wing, 2nd Floor, 711 Concession Street, Hamilton, ON L8V 1C3, Canada
BMC Health Serv Res 10:123. 2010....
The guideline implementability research and application network (GIRAnet): an international collaborative to support knowledge exchange: study protocolAnna R Gagliardi
University Health Network, Toronto, ON, Canada
Implement Sci 7:26. 2012..Further research is needed to develop and evaluate implementability tools...
Keeping cancer guidelines current: results of a comprehensive prospective literature monitoring strategy for twenty clinical practice guidelinesMary E Johnston
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Int J Technol Assess Health Care 19:646-55. 2003....
Integrating guideline development and implementation: analysis of guideline development manual instructions for generating implementation adviceAnna R Gagliardi
University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
Implement Sci 7:67. 2012..Others hypothesized this is due to limited instructions in guideline development manuals. The purpose of this study was to examine manual instructions for implementation advice...
The systematic review and bibliometric network analysis (SeBriNA) is a new method to contextualize evidence. Part 1: descriptionMichelle E Kho
Department of Physical Medicine and Rehabilitation, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA
J Clin Epidemiol 65:1010-5. 2012....
Application of the systematic review and bibliometric network analysis (SeBriNA) methodology contextualizes evidence. Part 2: rituximab for non-Hodgkin's lymphomaMichelle E Kho
Department of Physical Medicine and Rehabilitation, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA
J Clin Epidemiol 65:996-1009. 2012..We conducted a systematic review and bibliometric network analysis (SeBriNA) of rituximab for non-Hodgkin's lymphoma...
Written informed consent and selection bias in observational studies using medical records: systematic reviewMichelle E Kho
Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S 4L8
BMJ 338:b866. 2009..To determine whether informed consent introduces selection bias in prospective observational studies using data from medical records, and consent rates for such studies...
Conference abstracts of a new oncology drug do not always lead to full publication: proceed with cautionMichelle E Kho
Program in Health Research Methodology, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
J Clin Epidemiol 62:752-8. 2009..Our objectives were to determine the full publication rate of a cohort of abstracts, median time to publication, and predictors of these relationships...
American Society of Clinical Oncology Clinical Practice Guidelines: formal systematic review-based consensus methodologyD Andrew Loblaw
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Clin Oncol 30:3136-40. 2012..This methodology is proposed for development of future ASCO guidelines on topics for which limited evidence is available...
How can we improve guideline use? A conceptual framework of implementabilityAnna R Gagliardi
Departments of Surgery and Department of Health Policy, Management and Evaluation and Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Implement Sci 6:26. 2011..The purpose of this study was to identify and define features that facilitate guideline use, and examine whether and how they are included in current guidelines...
Canadian Thoracic Society: Presenting a new process for clinical practice guideline productionSamir Gupta
St Michael s Hospital, Toronto, Ontario, Canada
Can Respir J 16:e62-8. 2009..Ultimately, it is anticipated that these changes will have a significant impact on the quality of care and clinical outcomes of individuals suffering from respiratory diseases across Canada...
Establishing a comprehensive continuum from an evidentiary base to policy development for health technologies: the Ontario experienceLeslie Levin
Ministry of Health and Long Term Care and University of Toronto, Ontario, Canada
Int J Technol Assess Health Care 23:299-309. 2007....
Adjuvant therapy for stage II colon cancer: a systematic review from the Cancer Care Ontario Program in evidence-based care's gastrointestinal cancer disease site groupAlvaro Figueredo
Hamilton Regional Cancer Centre, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main St W, T 27, 3rd Floor, Hamilton, Ontario, Canada L8S 4L8
J Clin Oncol 22:3395-407. 2004..To develop a systematic review that would address the following question: Should patients with stage II colon cancer receive adjuvant therapy?..
