Uma Athale

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: an impact of peripheral blasts
    Uma Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 54:963-9. 2010
  2. ncbi Do children with central venous line (CVL) dysfunction have increased risk of symptomatic thromboembolism compared to those without CVL-dysfunction, while on cancer therapy?
    Jacqueline Halton
    The Children s Hospital of Eastern Ontario CHEO, Ottawa, ON, Canada
    BMC Cancer 12:314. 2012
  3. ncbi Central venous line dysfunction is an independent predictor of poor survival in children with cancer
    Uma H Athale
    Department of Pediatrics, McMaster University, ON, Canada
    J Pediatr Hematol Oncol 34:188-93. 2012
  4. ncbi Childhood atypical teratoid rhabdoid tumor of the central nervous system: a meta-analysis of observational studies
    Uma H Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Canada
    J Pediatr Hematol Oncol 31:651-63. 2009
  5. ncbi Thromboembolism in children with lymphoma
    Uma H Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, ON, Canada
    Thromb Res 122:459-65. 2008
  6. ncbi Thromboembolism in children with sarcoma
    Uma Athale
    Department of Pediatrics, Division of Hematology, McMaster University, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 49:171-6. 2007
  7. ncbi Epidemiology and clinical risk factors predisposing to thromboembolism in children with cancer
    Uma Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 51:792-7. 2008
  8. ncbi Thromboembolism in children with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute protocols: effect of age and risk stratification of disease
    Uma H Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, ON, Canada
    Br J Haematol 129:803-10. 2005
  9. ncbi Thrombosis in children with acute lymphoblastic leukemia Part III. Pathogenesis of thrombosis in children with acute lymphoblastic leukemia: effects of host environment
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, 3N27D, HSC, McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
    Thromb Res 111:321-7. 2003
  10. ncbi Thrombosis in children with acute lymphoblastic leukemia. Part II. Pathogenesis of thrombosis in children with acute lymphoblastic leukemia: effects of the disease and therapy
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, 3N27D, HSC, McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
    Thromb Res 111:199-212. 2003

Collaborators

Detail Information

Publications17

  1. ncbi von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: an impact of peripheral blasts
    Uma Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 54:963-9. 2010
    ..Steroids may contribute to ALL-associated thrombosis. We explored the hemostatic effects of methylprednisolone monotherapy (MpMT) (32 mg/m2/day IV x 3 days) in children with newly diagnosed ALL...
  2. ncbi Do children with central venous line (CVL) dysfunction have increased risk of symptomatic thromboembolism compared to those without CVL-dysfunction, while on cancer therapy?
    Jacqueline Halton
    The Children s Hospital of Eastern Ontario CHEO, Ottawa, ON, Canada
    BMC Cancer 12:314. 2012
    ..Despite these observations, to date there are no prospective studies to evaluate the clinical significance of CVL-dysfunction and it's impact on the development of TE, infection, or outcome of children with cancer...
  3. ncbi Central venous line dysfunction is an independent predictor of poor survival in children with cancer
    Uma H Athale
    Department of Pediatrics, McMaster University, ON, Canada
    J Pediatr Hematol Oncol 34:188-93. 2012
    ..23-3.41; P=0.018). Although the etiology of adverse impact of CVL-dysfunction on survival is unknown, its prevention and prompt treatment may improve outcome from cancer in children. Further prospective studies are recommended...
  4. ncbi Childhood atypical teratoid rhabdoid tumor of the central nervous system: a meta-analysis of observational studies
    Uma H Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Canada
    J Pediatr Hematol Oncol 31:651-63. 2009
    ..Therapy for central nervous system (CNS) atypical teratoid rhabdoid tumor (ATRT) is controversial. We describe 4 children treated with sarcoma-like therapy and review the literature to evaluate outcome in relation to treatment modalities...
  5. ncbi Thromboembolism in children with lymphoma
    Uma H Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, ON, Canada
    Thromb Res 122:459-65. 2008
    ..However, the epidemiology of thrombosis in children with cancer is largely unknown. We undertook the following study to define the epidemiology and to identify the risk factors predisposing children with lymphoma to thrombosis...
  6. ncbi Thromboembolism in children with sarcoma
    Uma Athale
    Department of Pediatrics, Division of Hematology, McMaster University, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 49:171-6. 2007
    ..Cancer has been identified as a major risk factor in children with TE. However, the information regarding the epidemiology of TE in children with cancer, especially in association with childhood solid tumors, is scant...
  7. ncbi Epidemiology and clinical risk factors predisposing to thromboembolism in children with cancer
    Uma Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 51:792-7. 2008
    ..This retrospective cohort study aims to determine the epidemiology of TE and to identify potential risk factors for TE in children with cancer...
  8. ncbi Thromboembolism in children with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute protocols: effect of age and risk stratification of disease
    Uma H Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, ON, Canada
    Br J Haematol 129:803-10. 2005
    ..Age-related risk may partly reflect the effect of ALL-risk stratification. Higher dose steroids combined with ASP may lead to an increased risk of TE in HR patients...
  9. ncbi Thrombosis in children with acute lymphoblastic leukemia Part III. Pathogenesis of thrombosis in children with acute lymphoblastic leukemia: effects of host environment
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, 3N27D, HSC, McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
    Thromb Res 111:321-7. 2003
    ..This will help to identify the population at risk for TE and for thromboprophylaxis, if indicated...
  10. ncbi Thrombosis in children with acute lymphoblastic leukemia. Part II. Pathogenesis of thrombosis in children with acute lymphoblastic leukemia: effects of the disease and therapy
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, 3N27D, HSC, McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
    Thromb Res 111:199-212. 2003
    ..Further studies to delineate the mechanism of increased thrombin in generation children with ALL and effects of various chemotherapeutic agents, in isolation and in combination, on haemostatic system are needed...
  11. ncbi Thrombosis in children with acute lymphoblastic leukemia: part I. Epidemiology of thrombosis in children with acute lymphoblastic leukemia
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, 3N27D, HSC, McMaster University, 1200 Main Street West, L8N3Z5, Hamilton, ON, Canada
    Thromb Res 111:125-31. 2003
    ..This review will be published in three parts. The first part will review the available information regarding epidemiology of TE in children with ALL...
  12. ncbi Thromboembolic complications in children with cancer
    John T Wiernikowski
    Division of Hematology/Oncology, McMaster Children's Hospital Hamilton, Ontario, Canada
    Thromb Res 118:137-52. 2006
    ..This review aims to examine current knowledge regarding the epidemiology, pathophysiology and management of thrombosis in association with cancer in children...
  13. ncbi Thromboembolic complications in pediatric hematologic malignancies
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Semin Thromb Hemost 33:416-26. 2007
    ..More prospective studies are required to define the epidemiology, pathogenesis, and management of TE in children with hematologic malignancies...
  14. ncbi Absence of secondary malignant neoplasms in children with high-risk acute lymphoblastic leukemia treated with dexrazoxane
    Elly V Barry
    Departments of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 26:1106-11. 2008
    ..We report the absence of an association of SMNs in children with acute lymphoblastic leukemia (ALL) treated on Dana-Farber Cancer Institute ALL Consortium Protocol 95-01...
  15. ncbi Hemorrhagic complications in pediatric hematologic malignancies
    Uma H Athale
    Division of Pediatric Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Semin Thromb Hemost 33:408-15. 2007
    ..Prospective studies are required to define the epidemiology and risk factors predisposing children with hematologic malignancy to bleeding and to develop management guidelines...
  16. ncbi Acute perforative appendicitis during preoperative chemotherapy for Wilms tumor
    Maria C Velez
    Louisiana State University Health Sciences Center and Children s Hospital of New Orleans, Department of Hematology Oncology, New Orleans, Louisiana 70118, USA
    Pediatr Hematol Oncol 20:147-50. 2003
    ..Problems related to diagnosis and management of acute abdominal pain and infection in an immunocompromised child with an abdominal mass are discussed along with a review of the literature...
  17. ncbi Phase I study of combination topotecan and carboplatin in pediatric solid tumors
    Uma H Athale
    Department of Hematology-Oncology, Pharmaceutical Sciences, St Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA
    J Clin Oncol 20:88-95. 2002
    ..The potential for preservation of activity and diminution of toxicity with alternative sequences and schedules of administration (topoisomerase followed by alkylating or platinating agents) should be evaluated...