D Armstrong

Summary

Affiliation: McMaster University
Country: Canada

Publications

  1. ncbi request reprint Symptom relief in gastroesophageal reflux disease: a randomized, controlled comparison of pantoprazole and nizatidine in a mixed patient population with erosive esophagitis or endoscopy-negative reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 96:2849-57. 2001
  2. pmc Canadian Association of Gastroenterology consensus guidelines on safety and quality indicators in endoscopy
    David Armstrong
    Division of Gastroenterrology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 26:17-31. 2012
  3. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
  4. pmc The impact of illness in patients with moderate to severe gastro-esophageal reflux disease
    Samer El-Dika
    Division of Gastroenterology, Veterans Affairs Medical Center, Salem, Virginia, USA
    BMC Gastroenterol 5:23. 2005
  5. pmc Canadian credentialing guidelines for endoscopic privileges: an overview
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Canada
    Can J Gastroenterol 21:797-801. 2007
  6. pmc Access to specialist gastroenterology care in Canada: the Practice Audit in Gastroenterology (PAGE) Wait Times Program
    D Armstrong
    McMaster Health Sciences Centre, Hamilton, Ontario, Canada
    Can J Gastroenterol 22:155-60. 2008
  7. doi request reprint A critical assessment of the current status of non-erosive reflux disease
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ont, Canada
    Digestion 78:46-54. 2008
  8. doi request reprint Systematic review: persistence and severity in gastro-oesophageal reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 28:841-53. 2008
  9. ncbi request reprint Validation of a short questionnaire in English and French for use in patients with persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy: the PASS (Proton pump inhibitor Acid Suppression Symptom) test
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 19:350-8. 2005
  10. ncbi request reprint Review article: gastric pH -- the most relevant predictor of benefit in reflux disease?
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 20:19-26; discussion 38-9. 2004

Collaborators

Detail Information

Publications86

  1. ncbi request reprint Symptom relief in gastroesophageal reflux disease: a randomized, controlled comparison of pantoprazole and nizatidine in a mixed patient population with erosive esophagitis or endoscopy-negative reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 96:2849-57. 2001
    ..The present study data suggest that pantoprazole is a highly effective first-line therapy for the management of gastroesophageal reflux disease in a primary care practice setting...
  2. pmc Canadian Association of Gastroenterology consensus guidelines on safety and quality indicators in endoscopy
    David Armstrong
    Division of Gastroenterrology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 26:17-31. 2012
    ....
  3. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
    ..The objective of this study was to assess correlates of treatment satisfaction in patients with GERD receiving a proton pump inhibitor, esomeprazole...
  4. pmc The impact of illness in patients with moderate to severe gastro-esophageal reflux disease
    Samer El-Dika
    Division of Gastroenterology, Veterans Affairs Medical Center, Salem, Virginia, USA
    BMC Gastroenterol 5:23. 2005
    ..Gastro-esophageal reflux disease (GERD) is a common disease. It impairs health related quality of life (HRQL). However, the impact on utility scores and work productivity in patients with moderate to severe GERD is not well known...
  5. pmc Canadian credentialing guidelines for endoscopic privileges: an overview
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Canada
    Can J Gastroenterol 21:797-801. 2007
  6. pmc Access to specialist gastroenterology care in Canada: the Practice Audit in Gastroenterology (PAGE) Wait Times Program
    D Armstrong
    McMaster Health Sciences Centre, Hamilton, Ontario, Canada
    Can J Gastroenterol 22:155-60. 2008
    ..Wait times for gastroenterology consultation and procedures have not been studied, although digestive diseases pose a greater economic burden in Canada than cancer or heart disease...
  7. doi request reprint A critical assessment of the current status of non-erosive reflux disease
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ont, Canada
    Digestion 78:46-54. 2008
    ....
  8. doi request reprint Systematic review: persistence and severity in gastro-oesophageal reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 28:841-53. 2008
    ..Management strategies for gastro-oesophageal reflux disease (GERD) are often inconsistent with the proposition that it is a persistent or chronic disease...
  9. ncbi request reprint Validation of a short questionnaire in English and French for use in patients with persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy: the PASS (Proton pump inhibitor Acid Suppression Symptom) test
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 19:350-8. 2005
    ....
  10. ncbi request reprint Review article: gastric pH -- the most relevant predictor of benefit in reflux disease?
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 20:19-26; discussion 38-9. 2004
    ..These data all suggest strongly that intragastric pH monitoring is an effective surrogate marker and a relevant predictor of outcome in gastro-oesophageal reflux disease...
  11. ncbi request reprint Review article: towards consistency in the endoscopic diagnosis of Barrett's oesophagus and columnar metaplasia
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 20:40-7; discussion 61-2. 2004
    ..It is hoped that these propositions will be the first step in the development of standard endoscopic diagnostic criteria for Barrett's oesophagus, relevant to clinical practice and clinical research...
  12. ncbi request reprint Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 21:1189-202. 2005
    ..There are few data on empiric, stepped therapy for heartburn relief or subsequent relapse in primary care...
  13. ncbi request reprint Canadian Consensus Conference on the management of gastroesophageal reflux disease in adults - update 2004
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton
    Can J Gastroenterol 19:15-35. 2005
    ..Since the last Canadian Consensus Conference in 1996, GERD management has evolved substantially...
  14. ncbi request reprint Gastroesophageal reflux disease
    David Armstrong
    Division of Gastroenterology, HSC 2F55, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario Canada L8N 3Z5
    Curr Opin Pharmacol 5:589-95. 2005
    ....
  15. pmc Point-of-care, peer-comparator colonoscopy practice audit: The Canadian Association of Gastroenterology Quality Program--Endoscopy
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton
    Can J Gastroenterol 25:13-20. 2011
    ..Point-of-care practice audits allow documentation of procedural outcomes to support quality improvement in endoscopic practice...
  16. ncbi request reprint The construction of a new evaluative GERD questionnaire--methods and state of the art
    David Armstrong
    McMaster University, Hamilton, Ont, Canada
    Digestion 75:17-24. 2007
    ....
  17. ncbi request reprint Early relief of upper gastrointestinal dyspeptic symptoms: a survey of empirical therapy with pantoprazole in Canadian clinical practice
    David Armstrong
    McMaster University Medical Centre, Hamilton, Canada
    Can J Gastroenterol 16:439-50. 2002
    ..Aim: To assess the range of upper gastrointestinal acid-related symptoms in clinical practice and the rapidity of their response to pantoprazole (40 mg daily), after seven days of therapy...
  18. doi request reprint Should patients with Barrett's oesophagus be kept under surveillance? The case for
    David Armstrong
    HSC 2F55, Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Best Pract Res Clin Gastroenterol 22:721-39. 2008
    ....
  19. ncbi request reprint Motion - All patients with GERD should be offered once in a lifetime endoscopy: arguments for the motion
    David Armstrong
    McMaster University Medical Centre, Hamilton, Canada
    Can J Gastroenterol 16:549-51. 2002
    ..The published evidence suggests that the application of clear guidelines would not overwhelm health care resources, and that fewer than 20% of patients with Barrett's esophagus would eventually undergo endoscopic surveillance...
  20. ncbi request reprint Oral rabeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 25:185-96. 2007
    ..Intravenous pantoprazole is often administered inappropriately to hospitalized patients who can take oral medications...
  21. pmc Practice Audit in Gastroenterology (PAGE) program: a novel approach to continuing professional development
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario
    Can J Gastroenterol 20:405-10. 2006
    ..This qualitative study assessed the use of personal digital assistants to facilitate data collection and review...
  22. ncbi request reprint Oral esomeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects
    D Armstrong
    Division of Gastroenterology, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada
    Aliment Pharmacol Ther 18:705-11. 2003
    ..Oral esomeprazole produces greater acid suppression than oral pantoprazole; however, no comparative data exist for oral esomeprazole and i.v. pantoprazole...
  23. ncbi request reprint The prevalence of Barrett's oesophagus in a cohort of 1040 Canadian primary care patients with uninvestigated dyspepsia undergoing prompt endoscopy
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:595-9. 2006
    ..The prevalence of Barrett's oesophagus in patients undergoing gastroscopy may be influenced by possible referral bias...
  24. ncbi request reprint Validation of a 7-point Global Overall Symptom scale to measure the severity of dyspepsia symptoms in clinical trials
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:521-9. 2006
    ..Currently there is no consensus on the optimal method to measure the severity of dyspepsia symptoms in clinical trials...
  25. ncbi request reprint Symptom overlap in patients with upper gastrointestinal complaints in the Canadian confirmatory acid suppression test (CAST) study: further psychometric validation of the reflux disease questionnaire
    S V Van Zanten
    Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
    Aliment Pharmacol Ther 25:1087-97. 2007
    ..The reflux disease questionnaire (RDQ) is a short, patient-completed instrument...
  26. ncbi request reprint Economic evaluation of Helicobacter pylori eradication in the CADET-Hp randomized controlled trial of H. pylori-positive primary care patients with uninvestigated dyspepsia
    N Chiba
    Surrey GI Clinic Research, Guelph, Ontario, Canada
    Aliment Pharmacol Ther 19:349-58. 2004
    ..omeprazole and placebo antimicrobials (OPP) in the Canadian Adult Dyspepsia Empiric Treatment-H. pylori-positive (CADET-Hp) study...
  27. doi request reprint The pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects
    R H Hunt
    Farncombe Family Digestive Disease Research Institute, Division of Gastroenterology, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada
    Aliment Pharmacol Ther 31:648-57. 2010
    ..Racemic tenatoprazole 40 mg/day provides more prolonged acid suppression than esomeprazole 40 mg/day...
  28. pmc Low prevalence of Helicobacter pylori infection in Canadian children: a cross-sectional analysis
    Idit Segal
    Department of Pediatrics, Division of Gastroenterology, BC Children s Hospital, Vancouver, Canada
    Can J Gastroenterol 22:485-9. 2008
    ..To date, few studies have assessed the prevalence of H pylori in Canadian children, with studies limited to Aboriginal communities and single tertiary care centres from Ontario and Quebec...
  29. ncbi request reprint Evidence-based recommendations for short- and long-term management of uninvestigated dyspepsia in primary care: an update of the Canadian Dyspepsia Working Group (CanDys) clinical management tool
    Sander J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie Medical School, Dalhousie University, Queen Elizabeth II Health Sciences Centre, 1278 Tower Road, Halifax, Nova Scotia B3H 2Y9, Canada
    Can J Gastroenterol 19:285-303. 2005
    ..When starting nonsteroidal anti-inflammatory drugs for a prolonged course, testing and treatment with H2RAs are advised if patients have a history of previous ulcers or ulcer bleeding...
  30. ncbi request reprint Validation of the GSFQ, a self-administered symptom frequency questionnaire for patients with gastroesophageal reflux disease
    Pierre Pare
    Division of Gastroenterology, Centre Hospitalier Affilié Universitaire de Québec Hôpital St Sacrement, 1050 Chemin Ste Foy, Quebec City, Quebec G1S 4L8, Canada
    Can J Gastroenterol 17:307-12. 2003
    ..The present article presents the validation of the short, self-administered GERD Symptom Frequency Questionnaire (GSFQ)...
  31. doi request reprint Predictable prolonged suppression of gastric acidity with a novel proton pump inhibitor, AGN 201904-Z
    R H Hunt
    Division of Gastroenterology, McMaster University and Hamilton Health Science Centre, Hamilton, ON, Canada
    Aliment Pharmacol Ther 28:187-99. 2008
    ..AGN 201904-Z is a new, slowly absorbed, acid-stable pro-proton pump inhibitor (pro-PPI) rapidly converted to omeprazole in the systemic circulation giving a prolonged residence time...
  32. ncbi request reprint Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease?
    C A Fallone
    Division of Gastroenterology, McGill University Health Center, Montreal, QC, Canada
    Aliment Pharmacol Ther 20:1161-9. 2004
    ..The accuracy of physicians' assessment of the severity of gastro-oesophageal reflux disease is unclear...
  33. ncbi request reprint Test and treat strategies for Helicobacter pylori in uninvestigated dyspepsia: a Canadian economic analysis
    J K Marshall
    Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Can J Gastroenterol 14:379-88. 2000
    ..Decision analysis was used to compare the cost effectiveness of empirical ranitidine with a test and treat strategy using either H pylori serology or the 13carbon-urea breath test (13C-UBT)...
  34. ncbi request reprint Intravenous proton pump inhibitor therapy: a rationale for use
    David Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Rev Gastroenterol Disord 5:S18-30. 2005
    ..IV PPIs, preoperatively and in the intensive care setting, effectively reduce gastric acidity, but there are no convincing data that this confers any significant clinical benefit compared with other therapeutic strategies...
  35. ncbi request reprint Pantoprazole rapidly improves health-related quality of life in patients with heartburn: a prospective, randomized, double blind comparative study with nizatidine
    Pierre Pare
    Hôpital St Sacrement, Division of Gastroenterology, 1050, Chemin Ste Foy, Quebec G1S 4L8, Canada
    J Clin Gastroenterol 37:132-8. 2003
    ..In the absence of an objective marker such as erosions, assessment of treatment efficacy can be based on symptoms and HRQoL...
  36. ncbi request reprint Esomeprazole 40 mg once a day in patients with functional dyspepsia: the randomized, placebo-controlled "ENTER" trial
    Sander Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, Canada
    Am J Gastroenterol 101:2096-106. 2006
    ..The objective of this study was to evaluate the efficacy of esomeprazole 40 mg once a day compared to placebo in achieving symptom relief in primary care patients with FD...
  37. ncbi request reprint The role of acid suppression in patients with endoscopy-negative reflux disease: the effect of treatment with esomeprazole or omeprazole
    D Armstrong
    McMaster University Medical Centre, Ontario, Canada
    Aliment Pharmacol Ther 20:413-21. 2004
    ..Standard-dose proton pump inhibitors can provide symptom relief in endoscopy-negative reflux disease but the effect of greater acid suppression has not been studied...
  38. pmc Endoscopic evaluation of gastro-esophageal reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Yale J Biol Med 72:93-100. 1999
    ..Non-erosive changes such as erythema may be ignored on the basis of present evidence, and there are no clear data to support the use of endoscopic biopsies for the diagnosis of GERD...
  39. doi request reprint Bacterial overgrowth syndrome in myotonic muscular dystrophy is potentially treatable
    Mark A Tarnopolsky
    Department of Pediatrics, McMaster University, 1200 Main Street West, HSC 2H26, Hamilton, Ontario L8N 3Z5, Canada
    Muscle Nerve 42:853-5. 2010
    ....
  40. doi request reprint The gain in quality-adjusted life months by switching to esomeprazole in those with continued reflux symptoms in primary care: EncomPASS--a cluster-randomized trial
    Paul Moayyedi
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Am J Gastroenterol 105:2341-6. 2010
    ..We expressed the data in terms of cost per quality-adjusted life months (QALM), as this was a 4-week trial...
  41. ncbi request reprint A comparison of narrative and table formats for presenting hypothetical health states to patients with gastrointestinal or pulmonary disease
    Holger J Schunemann
    McMaster University Health Sciences Centre, Room 2C12, Hamilton, Ontario, L8N 3Z5, Canada
    Med Decis Making 24:53-60. 2004
    ..Investigators should consider using the table presentation for describing health states to subjects who are not familiar with these states of health...
  42. ncbi request reprint Economic analysis of home vs hospital-based parenteral nutrition in Ontario, Canada
    John K Marshall
    Department of Medicine, Division of Gastroenterology, McMaster University Medical Center, Hamilton, Ontario, Canada
    JPEN J Parenter Enteral Nutr 29:266-9. 2005
    ..We undertook a retrospective cohort study of patients transferred from hospital to home while receiving home parenteral nutrition (PN) to assess their costs of care...
  43. ncbi request reprint A randomized controlled trial of laparoscopic nissen fundoplication versus proton pump inhibitors for treatment of patients with chronic gastroesophageal reflux disease: One-year follow-up
    Mehran Anvari
    Centre for Minimal Access Surgery, Department of Surgery, St Joseph s Healthcare, 50 Charlton Ave E, Hamilton, ON, L8N 4A6 Canada
    Surg Innov 13:238-49. 2006
    ..Patients controlled on long-term proton pump inhibitor therapy for chronic gastroesophageal reflux disease are excellent surgical candidates and should experience improved symptom control after surgery at 1 year...
  44. ncbi request reprint A randomized multicenter trial to evaluate simple utility elicitation techniques in patients with gastroesophageal reflux disease
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA
    Med Care 42:1132-42. 2004
    ..We evaluated whether the administration of marker states improves measurement properties of the FT and SG...
  45. ncbi request reprint The construction of a new evaluative GERD questionnaire - methods and state of the art
    David Armstrong
    HSC 4W8, Division of Gastroenterology, McMaster University, 1200 Mian Street West, Hamilton, Ontario L8N 3Z5, Canada
    Digestion 70:71-8. 2004
    ....
  46. ncbi request reprint Injection of botulinum toxin A to the upper esophageal sphincter for oropharyngeal dysphagia in two patients with inclusion body myositis
    Louis W C Liu
    Hamilton Health Sciences, Hamilton, Ontario, Canada
    Can J Gastroenterol 18:397-9. 2004
    ....
  47. ncbi request reprint Body-weight-support treadmill training improves blood glucose regulation in persons with incomplete spinal cord injury
    Stuart M Phillips
    Department of Kinesiology, Exercise and Metabolism Research Group, Centre for Health Promotion and Rehabilitation, McMaster University, 1280 Main St West, Hamilton, ON, Canada L8S 4K1
    J Appl Physiol 97:716-24. 2004
    ..Increases in the capacity for transport and phosphorylation glucose in skeletal muscle likely play a role in these adaptations...
  48. ncbi request reprint The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting
    Alan Barkun
    Department of Medicine, Division of Gastroenterology, McGill University, Montreal, Canada
    Am J Gastroenterol 99:1238-46. 2004
    ..From the Canadian Registry of patients with Upper Gastrointestinal Bleeding and Endoscopy (RUGBE), we determined clinical outcomes and explored the roles of endoscopic and pharmacologic therapies in a contemporary real-life setting...
  49. ncbi request reprint Addition of glutamine to essential amino acids and carbohydrate does not enhance anabolism in young human males following exercise
    Sarah B Wilkinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
    Appl Physiol Nutr Metab 31:518-29. 2006
    ..The addition of glutamine to a CHO + EAA beverage had no effect on post-exercise muscle glycogen resynthesis or muscle protein synthesis, but may suppress a rise in whole-body proteolysis during the later stages of recovery...
  50. ncbi request reprint A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN Study
    Sander J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, Nova Scotia, Canada
    Am J Gastroenterol 100:1477-88. 2005
    ..The management of Helicobacter pylori negative patients with dyspepsia in primary care has not been studied in placebo-controlled studies...
  51. doi request reprint The impact of intensifying acid suppression on sleep disturbance related to gastro-oesophageal reflux disease in primary care
    P Moayyedi
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 37:730-7. 2013
    ..Sleep disturbance is common in patients with GERD but there has been little evaluation of this problem in primary care in patients already taking therapy...
  52. ncbi request reprint Efficacy of H2 receptor antagonists in the treatment of gastroesophageal reflux disease and its symptoms
    G Tougas
    Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario
    Can J Gastroenterol 11:51B-54B. 1997
    ..The availability of H2 receptor antagonists for over-the-counter use will increase their use for mild and intermittent disease but is unlikely to alter the need for more potent acid suppression in aggressive reflux disease...
  53. pmc 13C urea breath test for (Helicobacter pylori): evaluation of 10-minute breath collection
    Marina Mauro
    Department of Medicine, McMaster University, Hamilton, Ontario
    Can J Gastroenterol 20:775-8. 2006
    ..To determine whether a shortened (13)C urea breath test ((13)C UBT) (breath collection time of 10 min) is as reliable as the standard assay (30 min)...
  54. ncbi request reprint Effect on intragastric pH of a PPI with a prolonged plasma half-life: comparison between tenatoprazole and esomeprazole on the duration of acid suppression in healthy male volunteers
    Richard H Hunt
    Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Am J Gastroenterol 100:1949-56. 2005
    ..To compare the inhibitory effect of a novel proton pump inhibitor (PPI), tenatoprazole 40 mg once daily, with esomeprazole 40 mg once daily on intragastric acidity...
  55. ncbi request reprint Survey of current perspectives on laryngopharyngeal reflux among Canadian otolaryngologists
    Taryn Davids
    Division of Otolaryngology, Head and Neck Surgery, University of Toronto, Toronto, ON, Canada
    J Otolaryngol Head Neck Surg 37:196-202. 2008
    ..Despite consensus guidelines, the presentation, diagnosis, and treatment remain controversial. We surveyed Canadian otolaryngologists to assess current perspectives...
  56. pmc 13C urea breath test for (Helicobacter pylori): determination of the optimal cut-off point in a Canadian community population
    Marina Mauro
    Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, Ontario
    Can J Gastroenterol 20:770-4. 2006
    ..To determine the test characteristics and the optimal cut-off point for the (13)C urea breath test ((13)C UBT) in a Canadian community laboratory setting...
  57. pmc Photodynamic therapy for Barrett's esophagus with high-grade dysplasia: a cost-effectiveness analysis
    Dan Comay
    Department of Medicine, Divison of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Can J Gastroenterol 21:217-22. 2007
    ..To assess the cost-effectiveness of photodynamic therapy (PDT) and esophagectomy (ESO) relative to surveillance (SURV) for patients with Barrett's esophagus (BE) and high-grade dysplasia (HGD)...
  58. ncbi request reprint Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting
    Robert A Enns
    Division of Gastroenterology, Department of Medicine, St Paul s Hospital, University of British Columbia, 300 1144 Burrard Street, Vancouver, BC, V6Z 2A5, Canada
    World J Gastroenterol 12:7779-85. 2006
    ..To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death...
  59. ncbi request reprint Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage
    Sarah B Wilkinson
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Canada
    Am J Clin Nutr 85:1031-40. 2007
    ..Proteins from different sources may differ in their ability to support muscle protein accretion because of different patterns of postprandial hyperaminoacidemia...
  60. doi request reprint Canadian home parenteral nutrition (HPN) registry: validation and patient outcomes
    G Fernandes
    University Health Network, Toronto General Hospital, Toronto, Ontario, Canada
    JPEN J Parenter Enteral Nutr 36:407-14. 2012
    ..In Canada, there are an estimated 400 home parenteral nutrition (HPN) patients. In 2006, a registry was created to gather patient outcome information. The aim of this study was to validate the registry and report on HPN patient outcomes...
  61. ncbi request reprint Angiography of primary central nervous system angiitis of childhood: conventional angiography versus magnetic resonance angiography at presentation
    R I Aviv
    Division of Neuroradiology, Hospital for Sick Children, Toronto, Ontario, Canada
    AJNR Am J Neuroradiol 28:9-15. 2007
    ....
  62. ncbi request reprint Evaluation of densitometric bone-muscle relationships in Crohn's disease
    Marina Mauro
    Intestinal Disease Research Program and Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Bone 40:1610-4. 2007
    ..Bone mass is affected both by nutrition and by muscular activity. Trauma excepted, the largest voluntary loads on bones come from muscle contraction, not body weight...
  63. ncbi request reprint Resistance training reduces fasted- and fed-state leucine turnover and increases dietary nitrogen retention in previously untrained young men
    Daniel R Moore
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    J Nutr 137:985-91. 2007
    ..The increase in nitrogen balance after training demonstrates a more efficient utilization of dietary nitrogen, suggesting that protein requirements for novice weightlifters are not elevated...
  64. pmc Canadian credentialing guidelines for esophagogastroduodenoscopy
    Terry Ponich
    Division of Gastroenterology, University of Western Ontario, London, Canada
    Can J Gastroenterol 22:349-54. 2008
  65. ncbi request reprint Preference-based antithrombotic therapy in atrial fibrillation: implications for clinical decision making
    Malcolm Man-Son-Hing
    Elisabeth Bruyere Research Institute and Division of Geriatric Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Med Decis Making 25:548-59. 2005
    ..The authors compared the thresholds for antithrombotic treatment from studies that determined or modeled the treatment preferences of patients with atrial fibrillation with recommendations from clinical practice guidelines...
  66. ncbi request reprint Noninvasive verification of nasogastric tube placement using a magnet-tracking system: a pilot study in healthy subjects
    Premysl Bercik
    Division of Gastroenterology and Intestinal Disease Research Program, McMaster University Medical Center, Hamilton, Ontario, Canada
    JPEN J Parenter Enteral Nutr 29:305-10. 2005
    ..Fluoroscopic verification of nasogastric (NG) feeding tube placement is inconvenient and involves radiation exposure. We tested whether the position of an NG tube can be assessed reliably by a recently introduced magnet-tracking system...
  67. ncbi request reprint Determination of ReQuest-based symptom thresholds to define symptom relief in GERD clinical studies
    Vincenzo Stanghellini
    Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Malpighi University Hospital, Via Massarento 9, IT 40138 Bologna, Italy
    Digestion 71:145-51. 2005
    ....
  68. ncbi request reprint GERD 2003 -- a consensus on the way ahead
    Steven F Moss
    Brown University, Providence, R I, USA
    Digestion 67:111-7. 2003
    ..Intestinal metaplasia in the lower esophagus is probably very common. Whether and how to, first, screen for, and then, perform surveillance in Barrett's esophagus remains highly problematic and contentious...
  69. ncbi request reprint GERD evaluation: time for a new paradigm?
    Irvin M Modlin
    Yale University School of Medicine, New Haven, CT 06520, USA
    J Clin Gastroenterol 41:237-41. 2007
    ..We propose that accurate symptom delineation complemented with endoscopy performed in selected groups of patients will become the mainstay in diagnosis of GERD and the assessment of therapy efficacy...
  70. ncbi request reprint Cetylated fatty acids improve knee function in patients with osteoarthritis
    Robert Hesslink
    Hesslink Ventures, San Diego, California, USA
    J Rheumatol 29:1708-12. 2002
    ..To determine the benefit of cetylated fatty acids (CFA) on knee range of motion and function in patients with osteoarthritis (OA)...
  71. ncbi request reprint Health-related quality of life and the transformation of symptoms
    David Armstrong
    Department of General Practice, King s College London, London, UK
    Sociol Health Illn 29:570-83. 2007
    ..Other contemporary examples of these free-floating symptoms reinforce the argument that the nature and meaning of symptoms has been transformed over recent decades...
  72. ncbi request reprint Simple clinical predictors may obviate urgent endoscopy in selected patients with nonvariceal upper gastrointestinal tract bleeding
    Joseph Romagnuolo
    Departments of Medicine and Biometry, Bioinformatics and Epidemiology, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Arch Intern Med 167:265-70. 2007
    ..The aims of this study were to predict whether the modified BRS (mBRS) can predict (1) endoscopic high-risk stigmata (HRS) and (2) rebleeding and mortality...
  73. ncbi request reprint Esomeprazole 40 mg and 20 mg is efficacious in the long-term management of patients with endoscopy-negative gastro-oesophageal reflux disease: a placebo-controlled trial of on-demand therapy for 6 months
    Nicholas J Talley
    Department of Medicine, University of Sydney, Clinical Science Building, Nepean Hospital, Penrith, Australia
    Eur J Gastroenterol Hepatol 14:857-63. 2002
    ..On-demand therapy may offer an effective approach to the long-term management of gastro-oesophageal reflux disease (GORD) without oesophagitis...
  74. ncbi request reprint The Work Productivity and Activity Impairment Questionnaire for Patients with Gastroesophageal Reflux Disease (WPAI-GERD): responsiveness to change and English language validation
    Peter Wahlqvist
    AstraZeneca R and D, Molndal, Sweden
    Pharmacoeconomics 25:385-96. 2007
    ..A validated productivity questionnaire, the Work Productivity and Activity Impairment questionnaire for Gastroesophageal Reflux Disease (WPAI-GERD), exists for Swedish patients with GERD...
  75. ncbi request reprint Determination of ReQuest-based symptom thresholds to define symptom relief in GERD clinical studies
    Vincenzo Stanghellini
    S Orsola Malpighi University Hospital, Bologna, Italy
    Digestion 75:55-61. 2007
    ....
  76. ncbi request reprint Effect of high-dose fluticasone propionate on bone density and metabolism in children with asthma
    Amanda L Griffiths
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, Clayton, and Centre for Heart and Chest Research, Monash University, Melbourne, Australia
    Pediatr Pulmonol 37:116-21. 2004
    ..This fell to 6/37 (16.2%) with bone age correction (NS). In conclusion, no significant reduction in bone metabolism or bone age-corrected bone mineral density was observed in children with asthma on prolonged high doses of inhaled FP...
  77. ncbi request reprint Women and health care professionals' preferences for Down's Syndrome screening tests: a conjoint analysis study
    Amanda J Bishop
    Psychology and Genetics Research Group, King s College London, UK
    BJOG 111:775-9. 2004
    ..To describe and compare women and health care professionals' preferences for Down's Syndrome screening tests with different test characteristics...
  78. doi request reprint A novel end point to assess a resident's ability to perform hand-assisted versus straight laparoscopy for left colectomy: is there really a difference?
    Bradley J Champagne
    Department of Surgery, Case Medical Center, Cleveland, OH 44106, USA
    J Am Coll Surg 207:554-9. 2008
    ..We measured the percentage of cases completed by a resident as the operating surgeon as the primary end point to determine the most effective approach for teaching laparoscopic colectomy...
  79. pmc What constructs do GPs use when diagnosing psychological problems?
    David Armstrong
    Department of General Practice, Guy s, King s and St Thomas School of Medicine, Kings College London
    Br J Gen Pract 54:580-3. 2004
    ..The mismatch between general practice and psychiatric diagnosis of psychological problems has been frequently reported...
  80. pmc Canadian credentialing guidelines for endoscopic retrograde cholangiopancreatography
    Johnathon Springer
    St Joseph s Health Centre, Toronto, Canada
    Can J Gastroenterol 22:547-51. 2008
  81. pmc Eliciting patients' concerns: a randomised controlled trial of different approaches by the doctor
    Malcolm McLean
    Henfield Medical Centre, West Sussex
    Br J Gen Pract 54:663-6. 2004
    ..Although a 'patient-centred' approach to general practice consultation is widely advocated, there is mixed evidence of its benefits...
  82. ncbi request reprint Accuracy of bracket placement by orthodontists and inexperienced dental students
    David Armstrong
    Department of Orthodontics, Faculty of Dentistry, Sydney Dental Hospital, The University of Sydney, Surry Hills, NSW, Australia
    Aust Orthod J 23:96-103. 2007
    ..Well-finished orthodontic treatment begins with accurate positioning of the brackets on the teeth...
  83. pmc The effect of sham feeding on neurocardiac regulation in healthy human volunteers
    M V Kamath
    Department of Medicine, McMaster University, Hamilton, Canada
    Can J Gastroenterol 21:721-6. 2007
    ..Sham feeding stimulates gastric acid secretion by means of vagal efferent pathways. It is not known, however, whether activation of vagal efferent pathways is organ- or stimulus-specific...
  84. ncbi request reprint Chronic illness: epidemiological or social explosion?
    David Armstrong
    Department of General Practice, King s College London, London, UK
    Chronic Illn 1:26-7; discussion 28-9. 2005
  85. ncbi request reprint Does the treatment of gastroesophageal reflux disease (GERD) meet patients' needs? A survey-based study
    Roger Jones
    King s College London, GKT Department of General Practice and Primary Care, UK
    Curr Med Res Opin 22:657-62. 2006
    ..A number of different therapies are prescribed to control the disease. This survey-based study was carried out to assess patients' and physicians' perceptions of GERD and its treatment...
  86. ncbi request reprint Provider and patient perspectives regarding health care for war-related health concerns
    Jamie D Davis
    Deployment Health Clinical Center, Walter Reed Army Medical Center, Washington, DC, USA
    Patient Educ Couns 68:52-60. 2007
    ..To gain insight about Department of Defense providers' and health care beneficiaries' opinions regarding provider-patient communication of health care for post-deployment health concerns...