Claire Dominique Walker

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi request reprint Increased colocalization of corticotropin-releasing factor and arginine vasopressin in paraventricular neurones of the hypothalamus in lactating rats: evidence from immunotargeted lesions and immunohistochemistry
    C D Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
    J Neuroendocrinol 13:74-85. 2001
  2. doi request reprint Naturally occurring variations in maternal care modulate the effects of repeated neonatal pain on behavioral sensitivity to thermal pain in the adult offspring
    Claire Dominique Walker
    Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Canada
    Pain 140:167-76. 2008
  3. ncbi request reprint A suckling feast: not so hot after all
    Claire Dominique Walker
    Department of Psychiatry, McGill University, Douglas Institute in Mental Health, 6875 LaSalle Boulevard, Montreal, Quebec, Canada H4H 1R3
    Endocrinology 148:4147-9. 2007
  4. ncbi request reprint Long-lasting effects of elevated neonatal leptin on rat hippocampal function, synaptic proteins and NMDA receptor subunits
    Claire Dominique Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    J Neurosci Res 85:816-28. 2007
  5. ncbi request reprint Nutritional aspects modulating brain development and the responses to stress in early neonatal life
    Claire Dominique Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, 6875 LaSalle Blvd, Verdun, QC, Canada H4H 1R3
    Prog Neuropsychopharmacol Biol Psychiatry 29:1249-63. 2005
  6. doi request reprint Perinatal maternal fat intake affects metabolism and hippocampal function in the offspring: a potential role for leptin
    Claire Dominique Walker
    Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, Quebec, Canada
    Ann N Y Acad Sci 1144:189-202. 2008
  7. pmc Mother to infant or infant to mother? Reciprocal regulation of responsiveness to stress in rodents and the implications for humans
    Claire Dominique Walker
    Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Douglas Hospital Research Centre, 6875 LaSalle Blvd, Montréal QC H4H IR3, Canada
    J Psychiatry Neurosci 29:364-82. 2004
  8. doi request reprint Maternal touch and feed as critical regulators of behavioral and stress responses in the offspring
    Claire Dominique Walker
    Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, Quebec, Canada
    Dev Psychobiol 52:638-50. 2010
  9. ncbi request reprint Hypothalamic and limbic expression of CRF and vasopressin during lactation: implications for the control of ACTH secretion and stress hyporesponsiveness
    C D Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
    Prog Brain Res 133:99-110. 2001
  10. doi request reprint Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring
    Esterina D'Asti
    Douglas Mental Health University Institute, McGill University, 6875 LaSalle Boulevard, Verdun, Quebec, Canada H4H 1R3
    Endocrinology 151:1685-94. 2010

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Increased colocalization of corticotropin-releasing factor and arginine vasopressin in paraventricular neurones of the hypothalamus in lactating rats: evidence from immunotargeted lesions and immunohistochemistry
    C D Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
    J Neuroendocrinol 13:74-85. 2001
    ..The opposite regulation of CRF and AVP gene expression during lactation might provide a useful model to study differential sensitivity to glucocorticoid feedback or hypothalamic activation of transcription factors...
  2. doi request reprint Naturally occurring variations in maternal care modulate the effects of repeated neonatal pain on behavioral sensitivity to thermal pain in the adult offspring
    Claire Dominique Walker
    Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Canada
    Pain 140:167-76. 2008
    ..These data suggest that changes in maternal behavior can influence some modalities of pain sensitivity and that repeated mild inflammatory pain in neonatal period causes hypersensitivity to formalin in the adult offspring...
  3. ncbi request reprint A suckling feast: not so hot after all
    Claire Dominique Walker
    Department of Psychiatry, McGill University, Douglas Institute in Mental Health, 6875 LaSalle Boulevard, Montreal, Quebec, Canada H4H 1R3
    Endocrinology 148:4147-9. 2007
  4. ncbi request reprint Long-lasting effects of elevated neonatal leptin on rat hippocampal function, synaptic proteins and NMDA receptor subunits
    Claire Dominique Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    J Neurosci Res 85:816-28. 2007
    ..Elevated exposure to leptin during a critical period of neonatal hippocampal development might serve to enhance NMDA-dependent functions other than LTP and have important effects on synaptogenesis and neurotransmitter release...
  5. ncbi request reprint Nutritional aspects modulating brain development and the responses to stress in early neonatal life
    Claire Dominique Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, 6875 LaSalle Blvd, Verdun, QC, Canada H4H 1R3
    Prog Neuropsychopharmacol Biol Psychiatry 29:1249-63. 2005
    ..The role of leptin, DHA and AA as mediators of the effects of fat on the brain is discussed...
  6. doi request reprint Perinatal maternal fat intake affects metabolism and hippocampal function in the offspring: a potential role for leptin
    Claire Dominique Walker
    Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, Quebec, Canada
    Ann N Y Acad Sci 1144:189-202. 2008
    ....
  7. pmc Mother to infant or infant to mother? Reciprocal regulation of responsiveness to stress in rodents and the implications for humans
    Claire Dominique Walker
    Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Douglas Hospital Research Centre, 6875 LaSalle Blvd, Montréal QC H4H IR3, Canada
    J Psychiatry Neurosci 29:364-82. 2004
    ....
  8. doi request reprint Maternal touch and feed as critical regulators of behavioral and stress responses in the offspring
    Claire Dominique Walker
    Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, Quebec, Canada
    Dev Psychobiol 52:638-50. 2010
    ....
  9. ncbi request reprint Hypothalamic and limbic expression of CRF and vasopressin during lactation: implications for the control of ACTH secretion and stress hyporesponsiveness
    C D Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
    Prog Brain Res 133:99-110. 2001
    ..Thus, it is possible that lactation-induced changes in the activity of parvocellular PVN neurons might also modulate the expression of neuropeptides and neurotransmitters in the BNST and the amygdala...
  10. doi request reprint Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring
    Esterina D'Asti
    Douglas Mental Health University Institute, McGill University, 6875 LaSalle Boulevard, Verdun, Quebec, Canada H4H 1R3
    Endocrinology 151:1685-94. 2010
    ..Thus, the nature of preweaning dietary fat differentially influences neonatal metabolic hormones, brain PL AA levels, and eCB, with functional consequences on hypothalamus-pituitary-adrenal axis modulation in developing rat pups...
  11. ncbi request reprint Does sucrose analgesia promote physiologic stability in preterm neonates?
    Kristina Boyer
    McGill University, Montreal, Canada
    Biol Neonate 85:26-31. 2004
    ..There was, however, a significant correlation between standard deviation of pulse rate and number of doses of sucrose only in the group who received high doses of sucrose...
  12. ncbi request reprint Diurnal salivary cortisol levels in postpartum mothers as a function of infant feeding choice and parity
    Mai Thanh Tu
    Department of Neurology and Neurosurgery, Douglas Hospital Research Center, McGill University, 6875 LaSalle Boulevard, Verdun Montreal, Que, Canada H4H 1R3
    Psychoneuroendocrinology 31:812-24. 2006
    ....
  13. ncbi request reprint Maternal high fat diet during the perinatal period alters mesocorticolimbic dopamine in the adult rat offspring: reduction in the behavioral responses to repeated amphetamine administration
    Lindsay Naef
    Department of Psychiatry, McGill University, Douglas Hospital Research Center, 6875 LaSalle Blvd, Montreal, QC, H4H 1R3, Canada
    Psychopharmacology (Berl) 197:83-94. 2008
    ..One critical variable in the early environment is nutrition, and exposure to high fat (HF) in adulthood is known to change this DA system...
  14. ncbi request reprint Leptin regulates appetite-related neuropeptides in the hypothalamus of developing rats without affecting food intake
    Karine Proulx
    McGill University, Department of Psychiatry, Douglas Hospital Research Center, Montreal, Quebec, Canada H4H 1R3
    Endocrinology 143:4683-92. 2002
    ..We conclude that despite adult-like effects of leptin on POMC, NPY, and CRFR-2 expression in neonates, leptin does not regulate food intake during early development...
  15. ncbi request reprint Routine sucrose analgesia during the first week of life in neonates younger than 31 weeks' postconceptional age
    C Celeste Johnston
    McGill University, School of Nursing, Montreal, QC, Canada
    Pediatrics 110:523-8. 2002
    ..To determine the efficacy of sucrose analgesia for procedural pain during the first week of life in preterm neonates in neonatal intensive care units on enhancing later clinical outcomes...
  16. doi request reprint High cortisol levels in the offspring of parents with bipolar disorder during two weeks of daily sampling
    Mark A Ellenbogen
    Centre for Research in Human Development, Concordia University, Montreal, Quebec, Canada
    Bipolar Disord 12:77-86. 2010
    ..The goal of the present study was to determine whether FH+ offspring, approximately two years later, continued to exhibit elevated cortisol levels relative to FH- offspring during two weeks of daily sampling...
  17. ncbi request reprint Repeated neonatal pain influences maternal behavior, but not stress responsiveness in rat offspring
    Claire Dominique Walker
    Department of Psychiatry, Douglas Hospital Research Center, 6875, Lasalle Blvd, PQ, H4H 1R3, Montreal, Canada
    Brain Res Dev Brain Res 140:253-61. 2003
    ....
  18. ncbi request reprint Animal models of long-term consequences of early exposure to repetitive pain
    C Celeste Johnston
    School of Nursing, McGill University, 3506 University St, Montreal, QC H3A 2A7, Canada
    Clin Perinatol 29:395-414. 2002
    ..With collaboration between these groups, more relevant research can be conducted that can lead to the decrease in pain and its consequences in neonates...
  19. ncbi request reprint The effects of exposure to repeated minor pain during the neonatal period on formalin pain behaviour and thermal withdrawal latencies
    C Celeste Johnston
    McGill University, Douglas Hospital Research Center, Montreal, Quebec, Canada
    Pain Res Manag 8:213-7. 2003
    ..Sex was significant at one age only in latency to thermal stimulation testing. The results suggest that changes in maternal care may be an important factor mediating the long-term effects of repeated neonatal experiences of pain...
  20. ncbi request reprint Feeding upon awakening in breastfeeding and bottlefeeding mothers does not affect the awakening cortisol response
    Mai Thanh Tu
    McGill University, Department of Neurology and Neurosurgery, Douglas Hospital Research Center, Montreal, Canada, H4H 1R3
    Stress 8:213-6. 2005
    ....
  21. ncbi request reprint Direct inhibitory effects of leptin on the neonatal adrenal and potential consequences for brain glucocorticoid feedback
    Claire Dominique Walker
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    Endocr Res 30:837-44. 2004
    ..Since circulating leptin levels in neonates vary according to maternal diet, this protein can be viewed as a critical link between environmental and maternal factors and the developing physiology of the infant...
  22. doi request reprint Effect of service dogs on salivary cortisol secretion in autistic children
    Robert Viau
    Fondation MIRA, 1820 rang Nord Ouest, Sainte Madeleine, Quebec, Canada
    Psychoneuroendocrinology 35:1187-93. 2010
    ..These results show that the CAR of children with ASD is sensitive to the presence of service dogs, which lends support to the potential behavioral benefits of service dogs for children with autism...
  23. pmc Kangaroo mother care diminishes pain from heel lance in very preterm neonates: a crossover trial
    C Celeste Johnston
    School of Nursing, McGill University, Montreal, Canada
    BMC Pediatr 8:13. 2008
    ..The purpose of this study was to determine if KMC would also be efficacious in very preterm neonates...
  24. ncbi request reprint Stress and selective attention: the interplay of mood, cortisol levels, and emotional information processing
    Mark A Ellenbogen
    Department of Psychology, Concordia University, Montreal, Quebec, Canada
    Psychophysiology 39:723-32. 2002
    ..These findings point to information-processing strategies as a means to regulate emotion, and to atypical features of cognitive and adrenocortical function that may serve as putative risk markers of depression...
  25. ncbi request reprint Measuring stress responses in postpartum mothers: perspectives from studies in human and animal populations
    Mai Thanh Tu
    Department of Psychiatry, Douglas Hospital Research Center, McGill University, Montreal, Canada
    Stress 8:19-34. 2005
    ..Knowing the reciprocal relationship in the mother-infant dyad, it is clear that investigation of the mechanisms regulating stress responses and mental health in postpartum mothers can only be beneficial to the development of the infant...
  26. ncbi request reprint Psychological stressors as a model of maternal adversity: diurnal modulation of corticosterone responses and changes in maternal behavior
    Marion Leonhardt
    CIHR program in Maternal Adversity, Vulnerability and Neurodevelopment MAVAN Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada H4H 1R3
    Horm Behav 51:77-88. 2007
    ..The combination of forced foraging, wet bedding and strobe light might represent a novel model of mild maternal adversity using "purely" psychological stressors...
  27. doi request reprint Therapeutic touch is not therapeutic for procedural pain in very preterm neonates: a randomized trial
    Celeste Johnston
    School of Nursing, McGill University Department of Anesthesia, University of Montreal, Montreal, QC IWK Health Centre, Halifax, NS McMaster University Health Centre, Hamilton, ON, Canada
    Clin J Pain 29:824-9. 2013
    ..The objective was to determine whether Therapeutic Touch is efficacious in decreasing pain in preterm neonates...
  28. pmc Brief communication: prenatal and early postnatal stress exposure influences long bone length in adult rat offspring
    Kelsey Needham Dancause
    Douglas Hospital Research Center, Montreal, QC, Canada
    Am J Phys Anthropol 149:307-11. 2012
    ..Stunting and growth retardation are major global health burdens. Our study adds to a growing body of evidence suggesting that PS is a risk factor for poor linear growth...
  29. doi request reprint Correlation of heart rate variability and circadian markers in humans
    Philippe Boudreau
    Centre for Study and Treatment of Circadian Rhythms, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada
    Conf Proc IEEE Eng Med Biol Soc 2011:681-2. 2011
    ....
  30. pmc Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus
    Francis Rodriguez Bambico
    Department of Psychiatry, McGill University, Montreal, QC, Canada
    Neuropsychopharmacology 35:2083-100. 2010
    ..Together, these results suggest that FAAH genetic deletion enhances anxiolytic-like and antidepressant-like effects, paralleled by altered 5-HT transmission and postsynaptic 5-HT(1A) and 5-HT(2A/2C) receptor function...
  31. doi request reprint Exposure to high fat during early development impairs adaptations in dopamine and neuroendocrine responses to repeated stress
    Lindsay Naef
    Department of Psychiatry and Integrated Program in Neuroscience, McGill University, Douglas Mental Health University Institute, Montreal, Quebec, Canada
    Stress 16:540-8. 2013
    ..Together, our data demonstrate that exposure to high fat during early development impairs adaptations in NAc DA and HPA responses usually observed with repeated stress. ..
  32. pmc Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeeding
    Ian Mahar
    Departments of Psychiatry, Neurology and Neurosurgery, Douglas Mental Health University Institute, McGill University, Verdun, Quebec, Canada
    PLoS ONE 7:e37219. 2012
    ..The influence of developmental nicotine exposure on the brain represents an important health topic in light of the popularity of nicotine replacement therapy (NRT) as a smoking cessation method during pregnancy...
  33. ncbi request reprint Daytime cortisol and stress reactivity in the offspring of parents with bipolar disorder
    Mark A Ellenbogen
    Centre for Research in Human Development, Concordia University, 7141 Sherbrooke Street West, Montreal, Quebec, Canada H4B 1R6
    Psychoneuroendocrinology 31:1164-80. 2006
    ..The offspring of parents with BD show evidence of increased daytime basal HPA functioning with normal reactivity to psychosocial stress...
  34. ncbi request reprint Inhibition of steroidogenic response to adrenocorticotropin by leptin: implications for the adrenal response to maternal separation in neonatal rats
    Camila Salzmann
    Department of Medicine, Faculty of Medicine, Universite de Sherbrooke, Canada
    Endocrinology 145:1810-22. 2004
    ..As leptin concentrations in pups are controlled to a large extent by the maternal diet, these results emphasize the key role of leptin to mediate the maternal influence on the adrenocortical axis of the infant...
  35. ncbi request reprint Automatic and effortful emotional information processing regulates different aspects of the stress response
    Mark A Ellenbogen
    Centre for Research in Human Development, Department of Psychology, Concordia University, 7141 Sherbrooke Street, Montreal, Que, Canada H4B 1R6
    Psychoneuroendocrinology 31:373-87. 2006
    ..Effortful and automatic processing appears to regulate different aspects of the stress response...
  36. doi request reprint Chronic maternal stress affects growth, behaviour and hypothalamo-pituitary-adrenal function in juvenile offspring
    Jeff Emack
    CIHR program in Maternal Adversity Vulnerability and Neurodevelopment MAVAN, University of Toronto, 1 King s College Circle, Toronto, Ontario, Canada
    Horm Behav 54:514-20. 2008
    ..In conclusion, CMS leads to modification of growth trajectory, locomotor activity and adrenocortical responses to stress in juvenile offspring. Further, males appear considerably more vulnerable to these effects than females...