P N Tonin

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families
    P N Tonin
    Departments of Human Genetics and Medicine, Division of Medical Genetics, McGill University, Montreal, Quebec, Canada
    Am J Hum Genet 63:1341-51. 1998
  2. ncbi request reprint Founder BRCA1 and BRCA2 mutations in early-onset French Canadian breast cancer cases unselected for family history
    P N Tonin
    Medical Genetics, Room L10 120, Montreal General Hospital Research Institute, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada
    Int J Cancer 95:189-93. 2001
  3. ncbi request reprint Genes implicated in hereditary breast cancer syndromes
    P N Tonin
    Department of Medicine, Division of Medical Genetics, McGill University, Montreal, Quebec, Canada
    Semin Surg Oncol 18:281-6. 2000
  4. ncbi request reprint Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and/or ovarian cancer families of French Canadian descent
    K K Oros
    Department of Human Genetics, McGill University, Canada
    Clin Genet 70:320-9. 2006
  5. ncbi request reprint Construction of a chromosome 17 transcriptome in serous ovarian cancer identifies differentially expressed genes
    P M Wojnarowicz
    Department of Human Genetics, McGill University, Montreal, Canada
    Int J Gynecol Cancer 18:963-75. 2008
  6. ncbi request reprint Transfer of chromosome 3 fragments suppresses tumorigenicity of an ovarian cancer cell line monoallelic for chromosome 3p
    N A L Cody
    Department of Human Genetics, McGill University, Montreal, Canada
    Oncogene 26:618-32. 2007
  7. ncbi request reprint Is there a correlation between the structure of hair and breast cancer or BRCA1/2 mutations?
    Khalid Laaziri
    Centre for the Physics of Materials, and Department of Physics, McGill University, Montreal, Quebec, Canada
    Phys Med Biol 47:1623-32. 2002
  8. pmc Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular classifiers of ovarian cancer
    C Le Page
    Centre de Recherche of the Center hospitalier de l Université de Montréal CR CHUM Institut du cancer de Montréal, Montreal, Quebec, Canada H2L 4M1
    Br J Cancer 94:436-45. 2006
  9. doi request reprint An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
    A Mamo
    Department of Oncology, Lady Davis Institute, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Oncogene 31:2090-100. 2012

Collaborators

  • W D Foulkes
  • P Ghadirian
  • C M Maugard
  • A M Mes-Masson
  • D M Provencher
  • A Mamo
  • P M Wojnarowicz
  • A Filali-Mouhim
  • N A L Cody
  • V Ouellet
  • K K Oros
  • C Le Page
  • Khalid Laaziri
  • K Malcolm
  • S Tuzmen
  • C Ferrario
  • E Przybytkowski
  • H Edgren
  • C Chabot
  • S Mousses
  • S Hassan
  • O Kallioniemi
  • O Aleynikova
  • L Cavallone
  • M Basik
  • A Breznan
  • S L Arcand
  • M Chevrette
  • M C J Quinn
  • P Tellis
  • M Zietarska
  • E N Manderson
  • Y Paredes
  • T J Hudson
  • J Madore
  • D Provencher
  • F Ren
  • C Perret
  • A J Paradis
  • A S Scott
  • M Sutton

Detail Information

Publications9

  1. pmc Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families
    P N Tonin
    Departments of Human Genetics and Medicine, Division of Medical Genetics, McGill University, Montreal, Quebec, Canada
    Am J Hum Genet 63:1341-51. 1998
    ..The identification of common BRCA1 and BRCA2 mutations will facilitate carrier detection in French Canadian breast cancer and breast/ovarian cancer families...
  2. ncbi request reprint Founder BRCA1 and BRCA2 mutations in early-onset French Canadian breast cancer cases unselected for family history
    P N Tonin
    Medical Genetics, Room L10 120, Montreal General Hospital Research Institute, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada
    Int J Cancer 95:189-93. 2001
    ..The identification of founder BRCA1 and BRCA2 mutations in young-onset breast cancer cases unselected for family history can facilitate carrier detection when the expected yield of a comprehensive screen may be low...
  3. ncbi request reprint Genes implicated in hereditary breast cancer syndromes
    P N Tonin
    Department of Medicine, Division of Medical Genetics, McGill University, Montreal, Quebec, Canada
    Semin Surg Oncol 18:281-6. 2000
    ..Host factors (such as lifestyle choices) and other genes may modulate risk of breast cancer in mutation carriers...
  4. ncbi request reprint Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and/or ovarian cancer families of French Canadian descent
    K K Oros
    Department of Human Genetics, McGill University, Canada
    Clin Genet 70:320-9. 2006
    ....
  5. ncbi request reprint Construction of a chromosome 17 transcriptome in serous ovarian cancer identifies differentially expressed genes
    P M Wojnarowicz
    Department of Human Genetics, McGill University, Montreal, Canada
    Int J Gynecol Cancer 18:963-75. 2008
    ..Interestingly, several of these differentially expressed genes have been previously associated with response to hypoxia...
  6. ncbi request reprint Transfer of chromosome 3 fragments suppresses tumorigenicity of an ovarian cancer cell line monoallelic for chromosome 3p
    N A L Cody
    Department of Human Genetics, McGill University, Montreal, Canada
    Oncogene 26:618-32. 2007
    ..The correlation of 3p12-pcen transfer and tumor suppression with a concerted re-programming of the cellular transcriptome suggest that the putative TSG may have affected key underlying events in ovarian cancer...
  7. ncbi request reprint Is there a correlation between the structure of hair and breast cancer or BRCA1/2 mutations?
    Khalid Laaziri
    Centre for the Physics of Materials, and Department of Physics, McGill University, Montreal, Quebec, Canada
    Phys Med Biol 47:1623-32. 2002
    ..The possible use of SAXS to diagnose cancer remains conjectural, but this and previous studies do not suggest that SAXS can be used as a reliable method of identifying either BRCA1/2 mutation carriers or women who have had breast cancer...
  8. pmc Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular classifiers of ovarian cancer
    C Le Page
    Centre de Recherche of the Center hospitalier de l Université de Montréal CR CHUM Institut du cancer de Montréal, Montreal, Quebec, Canada H2L 4M1
    Br J Cancer 94:436-45. 2006
    ....
  9. doi request reprint An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
    A Mamo
    Department of Oncology, Lady Davis Institute, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Oncogene 31:2090-100. 2012
    ..Finally, we found that ARID1A re-expression in the T47D cell line results in significant inhibition of colony formation in soft agar. These results suggest that ARID1A may be a candidate TSG in breast cancer...