Jose G Teodoro

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. doi request reprint Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy
    Linda Smolders
    McGill University, Goodman Cancer Research Centre, Department of Biochemistry, 1160 Pine Avenue West, Room 616, Montreal, Quebec H3A 1A3, Canada
    Expert Opin Ther Targets 15:767-80. 2011
  2. pmc DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin
    Thomas J Kucharski
    Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada H3A 1A3
    J Virol 85:12638-49. 2011
  3. ncbi request reprint Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome
    Jose G Teodoro
    McGill Cancer Centre, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Mol Med (Berl) 85:1175-86. 2007
  4. doi request reprint p53 inhibits angiogenesis by inducing the production of Arresten
    Sarah Assadian
    Goodman Cancer Research Center, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    Cancer Res 72:1270-9. 2012
  5. pmc Localization and importance of the adenovirus E4orf4 protein during lytic infection
    Marie Joëlle Miron
    Department of Biochemistry, McGill University, Montreal, Canada
    J Virol 83:1689-99. 2009
  6. pmc Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol
    Regina Cencic
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    PLoS ONE 4:e5223. 2009
  7. ncbi request reprint Regulation of collagen-derived antiangiogenic factors by p53
    Sarah Assadian
    McGill University, McGill Cancer Center, 3655 Promenade Sir William Osler, Montreal, QC, Canada
    Expert Opin Biol Ther 8:941-50. 2008
  8. ncbi request reprint p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase
    Jose G Teodoro
    Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 313:968-71. 2006

Collaborators

  • Fred Saad
  • Philip E Branton
  • Sarah Assadian
  • Thomas J Kucharski
  • Linda Smolders
  • Marie Joëlle Miron
  • Regina Cencic
  • Josee Dostie
  • Phillipe O Gannon
  • Anne Marie Mes-Masson
  • Véronique Barrès
  • Mathieu Latour
  • Xue Q D Wang
  • Wissal El-Assaad
  • Yoshikazu Sado
  • Isabelle Gamache
  • Ole Gjoerup
  • Brigitte Brem
  • Marie Eve Bordeleau
  • Thomas Dobner
  • Annie Bourdeau
  • Harald Greger
  • Jerry Pelletier
  • John A Porco
  • Gabriela Galicia-Vázquez
  • Rami Sukarieh
  • Frederic Dallaire
  • Marilyn Carrier
  • Suiyang Li
  • Paola Blanchette
  • Peter Groitl
  • Michel L Tremblay

Detail Information

Publications8

  1. doi request reprint Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy
    Linda Smolders
    McGill University, Goodman Cancer Research Centre, Department of Biochemistry, 1160 Pine Avenue West, Room 616, Montreal, Quebec H3A 1A3, Canada
    Expert Opin Ther Targets 15:767-80. 2011
    ..Some viral proteins cause cytotoxicity specifically in tumour cells, providing evidence that targeting the APC/C could be exploited to selectively eliminate cancer cells...
  2. pmc DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin
    Thomas J Kucharski
    Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada H3A 1A3
    J Virol 85:12638-49. 2011
    ..We observe that Apoptin is able to inhibit formation of DNA damage foci by targeting the APC/C-associated factor MDC1 for degradation. We suggest that these results may point to a novel mechanism of DDR inhibition during viral infection...
  3. ncbi request reprint Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome
    Jose G Teodoro
    McGill Cancer Centre, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Mol Med (Berl) 85:1175-86. 2007
    ..Thus, the loss of functional p53 during tumorigenesis likely represents an essential step in the switch to an angiogenic phenotype that is displayed by aggressive tumors...
  4. doi request reprint p53 inhibits angiogenesis by inducing the production of Arresten
    Sarah Assadian
    Goodman Cancer Research Center, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    Cancer Res 72:1270-9. 2012
    ..Our findings, therefore, link the production of Arresten to the p53 tumor suppressor pathway and show a novel mechanism through which p53 can inhibit angiogenesis...
  5. pmc Localization and importance of the adenovirus E4orf4 protein during lytic infection
    Marie Joëlle Miron
    Department of Biochemistry, McGill University, Montreal, Canada
    J Virol 83:1689-99. 2009
    ....
  6. pmc Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol
    Regina Cencic
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    PLoS ONE 4:e5223. 2009
    ..One flavagline, silvestrol, is capable of modulating chemosensitivity in a mechanism-based mouse model...
  7. ncbi request reprint Regulation of collagen-derived antiangiogenic factors by p53
    Sarah Assadian
    McGill University, McGill Cancer Center, 3655 Promenade Sir William Osler, Montreal, QC, Canada
    Expert Opin Biol Ther 8:941-50. 2008
    ..This effect is partly mediated by the ability of p53 to increase production of endogenous angiogenesis inhibitors, such as the collagen-derived antiangiogenic factors (CDAFs), endostatin and tumstatin...
  8. ncbi request reprint p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase
    Jose G Teodoro
    Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 313:968-71. 2006
    ..Our results reveal a genetic and biochemical linkage between the p53 tumor suppressor pathway and the synthesis of antiangiogenic collagen fragments...