Jose G Teodoro

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy
    Linda Smolders
    McGill University, Goodman Cancer Research Centre, Department of Biochemistry, 1160 Pine Avenue West, Room 616, Montreal, Quebec H3A 1A3, Canada
    Expert Opin Ther Targets 15:767-80. 2011
  2. ncbi DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin
    Thomas J Kucharski
    Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada H3A 1A3
    J Virol 85:12638-49. 2011
  3. ncbi Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome
    Jose G Teodoro
    McGill Cancer Centre, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Mol Med (Berl) 85:1175-86. 2007
  4. ncbi p53 inhibits angiogenesis by inducing the production of Arresten
    Sarah Assadian
    Goodman Cancer Research Center, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    Cancer Res 72:1270-9. 2012
  5. ncbi Localization and importance of the adenovirus E4orf4 protein during lytic infection
    Marie Joëlle Miron
    Department of Biochemistry, McGill University, Montreal, Canada
    J Virol 83:1689-99. 2009
  6. ncbi Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol
    Regina Cencic
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    PLoS ONE 4:e5223. 2009
  7. ncbi Regulation of collagen-derived antiangiogenic factors by p53
    Sarah Assadian
    McGill University, McGill Cancer Center, 3655 Promenade Sir William Osler, Montreal, QC, Canada
    Expert Opin Biol Ther 8:941-50. 2008
  8. ncbi p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase
    Jose G Teodoro
    Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 313:968-71. 2006

Collaborators

  • Fred Saad
  • Philip E Branton
  • Sarah Assadian
  • Linda Smolders
  • Thomas J Kucharski
  • Regina Cencic
  • Marie Joëlle Miron
  • Anne Marie Mes-Masson
  • Xue Q D Wang
  • Yoshikazu Sado
  • Phillipe O Gannon
  • Mathieu Latour
  • Josee Dostie
  • Wissal El-Assaad
  • Véronique Barrès
  • Isabelle Gamache
  • Ole Gjoerup
  • Marilyn Carrier
  • Rami Sukarieh
  • Jerry Pelletier
  • John A Porco
  • Gabriela Galicia-Vázquez
  • Marie Eve Bordeleau
  • Peter Groitl
  • Thomas Dobner
  • Michel L Tremblay
  • Suiyang Li
  • Paola Blanchette
  • Brigitte Brem
  • Annie Bourdeau
  • Harald Greger
  • Frederic Dallaire

Detail Information

Publications8

  1. ncbi Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy
    Linda Smolders
    McGill University, Goodman Cancer Research Centre, Department of Biochemistry, 1160 Pine Avenue West, Room 616, Montreal, Quebec H3A 1A3, Canada
    Expert Opin Ther Targets 15:767-80. 2011
    ..Tumour cells display greater dependency on APC/C function than normal cells and oncogenic transformation can lead to increased mitotic stress, rendering cancer cells more vulnerable to APC/C inhibition...
  2. ncbi DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin
    Thomas J Kucharski
    Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada H3A 1A3
    J Virol 85:12638-49. 2011
    ..We observe that Apoptin is able to inhibit formation of DNA damage foci by targeting the APC/C-associated factor MDC1 for degradation. We suggest that these results may point to a novel mechanism of DDR inhibition during viral infection...
  3. ncbi Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome
    Jose G Teodoro
    McGill Cancer Centre, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Mol Med (Berl) 85:1175-86. 2007
    ..Thus, the loss of functional p53 during tumorigenesis likely represents an essential step in the switch to an angiogenic phenotype that is displayed by aggressive tumors...
  4. ncbi p53 inhibits angiogenesis by inducing the production of Arresten
    Sarah Assadian
    Goodman Cancer Research Center, Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    Cancer Res 72:1270-9. 2012
    ..Our findings, therefore, link the production of Arresten to the p53 tumor suppressor pathway and show a novel mechanism through which p53 can inhibit angiogenesis...
  5. ncbi Localization and importance of the adenovirus E4orf4 protein during lytic infection
    Marie Joëlle Miron
    Department of Biochemistry, McGill University, Montreal, Canada
    J Virol 83:1689-99. 2009
    ....
  6. ncbi Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol
    Regina Cencic
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    PLoS ONE 4:e5223. 2009
    ..One flavagline, silvestrol, is capable of modulating chemosensitivity in a mechanism-based mouse model...
  7. ncbi Regulation of collagen-derived antiangiogenic factors by p53
    Sarah Assadian
    McGill University, McGill Cancer Center, 3655 Promenade Sir William Osler, Montreal, QC, Canada
    Expert Opin Biol Ther 8:941-50. 2008
    ..This effect is partly mediated by the ability of p53 to increase production of endogenous angiogenesis inhibitors, such as the collagen-derived antiangiogenic factors (CDAFs), endostatin and tumstatin...
  8. ncbi p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase
    Jose G Teodoro
    Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 313:968-71. 2006
    ..Our results reveal a genetic and biochemical linkage between the p53 tumor suppressor pathway and the synthesis of antiangiogenic collagen fragments...