Affiliation: McGill University
- Szyf M, Tang Y, Hill K, Musci R. The dynamic epigenome and its implications for behavioral interventions: a role for epigenetics to inform disorder prevention and health promotion. Transl Behav Med. 2016;6:55-62 pubmed publisher..In spite of this great potential promise of the emerging field of social and translational epigenetics, many practical challenges remain that must be addressed before behavioral epigenetics could become translational epigenetics. ..
- Cao Lei L, de Rooij S, King S, Matthews S, Metz G, Roseboom T, et al. Prenatal stress and epigenetics. Neurosci Biobehav Rev. 2017;: pubmed publisher..We also emphasized the advantage of using stressor from quasi-randomly assigned experiments. Furthermore, we discuss challenges that still need to be addressed in this field in the future. ..
- Stefanska B, Cheishvili D, Suderman M, Arakelian A, Huang J, Hallett M, et al. Genome-wide study of hypomethylated and induced genes in patients with liver cancer unravels novel anticancer targets. Clin Cancer Res. 2014;20:3118-32 pubmed publisher..Because these genes are particularly activated in cancer, they constitute a group of targets for specific pharmacologic inhibitors of cancer and cancer metastasis. Clin Cancer Res; 20(12); 3118-32. ©2014 AACR. ..
- Weaver I, Hellstrom I, Brown S, Andrews S, Dymov S, Diorio J, et al. The methylated-DNA binding protein MBD2 enhances NGFI-A (egr-1)-mediated transcriptional activation of the glucocorticoid receptor. Philos Trans R Soc Lond B Biol Sci. 2014;369: pubmed publisher..These data suggest a possible mechanism linking signalling pathways, which are activated by behavioural stimuli and activation of target genes. ..