Andrew Szilagyi

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi Diminished efficacy of colonic adaptation to lactulose occurs in patients with inflammatory bowel disease in remission
    Andrew Szilagyi
    Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Dig Dis Sci 47:2811-22. 2002
  2. ncbi Deadaption and readaptation with lactose, but no cross-adaptation to lactulose: a case of occult colonic bacterial adaptation
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, School of Medicine, Montreal, Quebec, Canada
    Can J Gastroenterol 18:677-80. 2004
  3. ncbi Meta-analysis of outcome of cytomegalovirus colitis in immunocompetent hosts
    Polymnia Galiatsatos
    Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Dig Dis Sci 50:609-16. 2005
  4. pmc Pharmacological therapy of vascular malformations of the gastrointestinal tract
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, Montreal, Quebec
    Can J Gastroenterol 20:171-8. 2006
  5. ncbi Comparison of a real-time polymerase chain reaction assay for lactase genetic polymorphism with standard indirect tests for lactose maldigestion
    Andrew Szilagyi
    Division of Gastroenterology, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Clin Gastroenterol Hepatol 5:192-6. 2007
  6. pmc Infliximab therapy for moderately severe Crohn's disease and ulcerative colitis: a retrospective comparison over 6 years
    Raed Alzafiri
    Jewish General Hospital, Division of Gastroenterology, Department of Medicine, McGill University School of Medicine, Montreal, Quebec, Canada
    Clin Exp Gastroenterol 4:9-17. 2011
  7. pmc Carbohydrate Elimination or Adaptation Diet for Symptoms of Intestinal Discomfort in IBD: Rationales for "Gibsons' Conundrum"
    Q Manyan Fung
    Division of Gastroenterology, Department of Medicine, Jewish General Hospital, McGill University School of Medicine, 3755 Cote Sainte Catherine Road, Room E110, Montreal, QC, Canada H3T 1E2
    Int J Inflam 2012:493717. 2012
  8. pmc Dynamics of vitamin D in patients with mild or inactive inflammatory bowel disease and their families
    Avigyle Grunbaum
    Gastroenterology, Jewish General Hospital, 3755 Cote Ste Catherine Rd, Room E177, Montreal, QC, Canada
    Nutr J 12:145. 2013
  9. ncbi Fructose malabsorption may be gender dependent and fails to show compensation by colonic adaptation
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Dig Dis Sci 52:2999-3004. 2007
  10. pmc Lack of effect of lactose digestion status on baseline fecal micoflora
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, Montreal, Canada
    Can J Gastroenterol 23:753-9. 2009

Collaborators

  • I Shrier
  • Nir Hilzenrat
  • Deborah Golberg
  • Polymnia Galiatsatos
  • Sunghoon Park
  • Alan N Barkun
  • Jamie Cassoff
  • Debra Heilpern
  • Avigyle Grunbaum
  • Carlo A Fallone
  • Q Manyan Fung
  • Raed Alzafiri
  • Majid Almadi
  • Albert Cohen
  • Waleed K Al-Hamoudi
  • Raffi Karagozian
  • Rose Yesovitch
  • Maryse Menard
  • Maida Sewitch
  • Karl M Herba
  • Philip H Gordon
  • Barry Burstein
  • Jasim Al-Abbad
  • Stefanie S Fallone
  • Elizabeth Macnamara
  • Christina Holcroft
  • Stephanie Gladman
  • Myriam Martel
  • Paula Malolepszy
  • Christina A Holcroft
  • Jacques Galipeau
  • Peter M Ghali
  • Andre Constantin
  • Lesley Alpert
  • Christian Turbide

Detail Information

Publications27

  1. ncbi Diminished efficacy of colonic adaptation to lactulose occurs in patients with inflammatory bowel disease in remission
    Andrew Szilagyi
    Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Dig Dis Sci 47:2811-22. 2002
    ..In conclusion, although controls adapt to a 3-week period of lactulose ingestion, IBD patients fail to meet the criteria for adaptation. However, longer studies may be needed to establish whether IBD patients are slower to adapt...
  2. ncbi Deadaption and readaptation with lactose, but no cross-adaptation to lactulose: a case of occult colonic bacterial adaptation
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, School of Medicine, Montreal, Quebec, Canada
    Can J Gastroenterol 18:677-80. 2004
    ..There is a relationship between variation in lactose intake and the results of BH2 testing. Finally, there was no cross-adaptation to lactulose challenge when lactose was used as the adapting sugar...
  3. ncbi Meta-analysis of outcome of cytomegalovirus colitis in immunocompetent hosts
    Polymnia Galiatsatos
    Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Dig Dis Sci 50:609-16. 2005
    ..Advanced age, male gender, presence of immune-modulating comorbidities, and need for surgical intervention are factors negatively influencing survival. Conversely, young healthy patients have a good prognosis with no intervention...
  4. pmc Pharmacological therapy of vascular malformations of the gastrointestinal tract
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, Montreal, Quebec
    Can J Gastroenterol 20:171-8. 2006
    ..The latter therapy has been reported only as case reports and case series without prospective trials. In addition, other anecdotally used medications are discussed...
  5. ncbi Comparison of a real-time polymerase chain reaction assay for lactase genetic polymorphism with standard indirect tests for lactose maldigestion
    Andrew Szilagyi
    Division of Gastroenterology, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Clin Gastroenterol Hepatol 5:192-6. 2007
    ..There is a discrepancy in outcome between the lactose tolerance and breath hydrogen tests for lactose maldigestion. The availability of a validated genetic test for lactase polymorphism allows a reevaluation of these tests...
  6. pmc Infliximab therapy for moderately severe Crohn's disease and ulcerative colitis: a retrospective comparison over 6 years
    Raed Alzafiri
    Jewish General Hospital, Division of Gastroenterology, Department of Medicine, McGill University School of Medicine, Montreal, Quebec, Canada
    Clin Exp Gastroenterol 4:9-17. 2011
    ..Infliximab has shown benefit in Crohn's disease (CD) and ulcerative colitis (UC)...
  7. pmc Carbohydrate Elimination or Adaptation Diet for Symptoms of Intestinal Discomfort in IBD: Rationales for "Gibsons' Conundrum"
    Q Manyan Fung
    Division of Gastroenterology, Department of Medicine, Jewish General Hospital, McGill University School of Medicine, 3755 Cote Sainte Catherine Road, Room E110, Montreal, QC, Canada H3T 1E2
    Int J Inflam 2012:493717. 2012
    ..This is particularly relevant in IBD. As such, caution is urged to use long-term carbohydrate withdrawal in IBD in remission to control IBS-like symptoms...
  8. pmc Dynamics of vitamin D in patients with mild or inactive inflammatory bowel disease and their families
    Avigyle Grunbaum
    Gastroenterology, Jewish General Hospital, 3755 Cote Ste Catherine Rd, Room E177, Montreal, QC, Canada
    Nutr J 12:145. 2013
    ..Furthermore there is limited information of any family influence on 25(OH) vitamin D levels in IBD. As a possible risk factor we hypothesize that vitamin D levels may also be low in families of IBD patients...
  9. ncbi Fructose malabsorption may be gender dependent and fails to show compensation by colonic adaptation
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Dig Dis Sci 52:2999-3004. 2007
    ..516, p = 0.0037). Adaptation with increasing pretest fructose intake was absent. We conclude that gender may influence fructose malabsorption and there is no adaptation to regular consumption...
  10. pmc Lack of effect of lactose digestion status on baseline fecal micoflora
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, Montreal, Canada
    Can J Gastroenterol 23:753-9. 2009
    ..A prebiotic effect of lactose may impact the colonic flora of these phenotypes differently...
  11. doi Determinants of geographic patterns of diseases: interaction of lactose/lactase status and sunshine exposure
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Jewish General Hospital, McGill University School of Medicine, Montreal, Quebec, Canada
    Med Hypotheses 75:466-70. 2010
    ..As such both discussed variables are postulated to exert parallel as well as independent effects on modifying geographic disease patterns. These could partly explain both north to south and west to east directional changes...
  12. pmc Differential impact of lactose/lactase phenotype on colonic microflora
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, McGill School of Medicine, Montreal, Quebec
    Can J Gastroenterol 24:373-9. 2010
    ..Prebiotic effects likely favour lactose maldigesters who experience lactose spilling into their colon...
  13. ncbi Evaluation of relationships among national colorectal cancer mortality rates, genetic lactase non-persistence status, and per capita yearly milk and milk product consumption
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, The Sir Mortimer B Davis Jewish General Hospital, McGill University, Canada
    Nutr Cancer 55:151-6. 2006
    ....
  14. ncbi The effect of lactose maldigestion on the relationship between dairy food intake and colorectal cancer: a systematic review
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, The Sir Mortimer B Davis Jewish General Hospital, McGill University, Canada
    Nutr Cancer 55:141-50. 2006
    ..These results raise the possibility that LNP/LP status may be partly responsible for the discrepant results with respect to the relationship between dairy food consumption and CRC...
  15. ncbi Inverse dose effect of pretest dietary lactose intake on breath hydrogen results and symptoms in lactase nonpersistent subjects
    Andrew Szilagyi
    Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Dig Dis Sci 50:2178-82. 2005
    ..05). In the presumed lactose digesters, 59% experienced some symptoms during testing for unclear reasons. Pretest dietary intake of lactose inversely affects results of breath hydrogen...
  16. doi Significant positive correlation between sunshine and lactase nonpersistence in Europe may implicate both in similarly altering risks for some diseases
    Andrew Szilagyi
    Jewish General Hospital, Department of Medicine, Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Nutr Cancer 63:991-9. 2011
    ..59, P < 0.001, whereas outside Europe: r(2) = 0.06, P = 0.16. These relationships raise hypothetical explanations to account for the observed overlap in similar risk modification by the 2 variables...
  17. ncbi Redefining lactose as a conditional prebiotic
    Andrew Szilagyi
    McGill University School of Medicine, The Sir Mortimer B, Davis Jewish General Hospital, Montreal, Quebec
    Can J Gastroenterol 18:163-7. 2004
    ..The present article examines scientific and clinical knowledge about the properties of lactose and argues that in lactase nonpersistent subjects, lactose qualifies as a prebiotic...
  18. pmc Recurrent obscure gastrointestinal bleeding: dilemmas and success with pharmacological therapies. Case series and review
    Majid Almadi
    Division of Gastroenterlogy, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Can J Gastroenterol 23:625-31. 2009
    ..In the third case, however, the addition of low-dose thalidomide stopped bleeding for a period of at least 23 months...
  19. doi Impact of lactose containing foods and the genetics of lactase on diseases: an analytical review of population data
    Ian Shrier
    Centre for Clinical Epidemiology and Community Studies, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Nutr Cancer 60:292-300. 2008
    ..In colorectal cancer, on the contrary, meta-analyses of case-based studies suggest protection. The possible importance of distinguishing LNP/LP status in studies is discussed...
  20. ncbi Failure to improve parameters of lactose maldigestion using the multiprobiotic product VSL3 in lactose maldigesters: a pilot study
    Rose Yesovitch
    Department of Medicine, McGill University School of Medicine, Montreal, Quebec
    Can J Gastroenterol 18:83-6. 2004
    ..In its present format, therefore, the test for colonic adaptation cannot be used to demonstrate direct bacterial embedding with VSL3...
  21. ncbi Manipulation of intestinal microbial flora for therapeutic benefit in inflammatory bowel diseases: review of clinical trials of probiotics, pre-biotics and synbiotics
    Debra Heilpern
    Department of Medicine, Division of Gastroenterology, Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, Montreal, Quebec, Canada
    Rev Recent Clin Trials 3:167-84. 2008
    ..Further studies with uniform stringent criteria are needed to provide proof of this therapy in inflammatory bowel disease...
  22. ncbi Prolonged treatment duration is required for successful Helicobacter pylori eradication with proton pump inhibitor triple therapy in Canada
    Carlo A Fallone
    Division of McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Can J Gastroenterol 27:397-402. 2013
    ..Prolonging therapy may be associated with poorer compliance and, hence, may not have a better outcome in a real-world setting...
  23. ncbi Hyperemesis gravidarum and Helicobacter pylori infection: a systematic review
    Deborah Golberg
    Department of Family Medicine, SMBD Jewish General Hospital, McGill University, Montreal, Canada
    Obstet Gynecol 110:695-703. 2007
    ..To systematically review studies examining the relationship between hyperemesis gravidarum and Helicobacter pylori (H pylori) infection...
  24. ncbi Accuracy of biopsies for Helicobacter pylori in the presence of intestinal metaplasia of the stomach
    Polymnia Galiatsatos
    Department of Gastroenterology, Sir Mortimer B Davis Jewish General Hospital, Montreal, Canada
    Turk J Gastroenterol 25:19-23. 2014
    ..Studies have demonstrated reversibility of mucosal atrophy following H. pylori eradication. Concern has been raised regarding the sensitivity of gastric biopsy for H. pylori detection in the context of IM...
  25. ncbi Use of prebiotics for inflammatory bowel disease
    Andrew Szilagyi
    Division of Gastroenterology, Faculty of Medicine, The Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, Montreal, Canada
    Can J Gastroenterol 19:505-10. 2005
    ..The present review elaborates on some of the background rationale and mechanisms on the use of prebiotics. Additionally, published animal and human trials are discussed...
  26. ncbi Henoch-Schonlein purpura presenting with ileal involvement in an adult
    Raffi Karagozian
    Division of Gastroenterology, Department of Medicine, McGill University School of Medicine, Montreal, Quebec, Canada
    Dig Dis Sci 49:1722-6. 2004
  27. ncbi Acute symptomatic gastritis due to Helicobacter heilmannii
    Waleed K Al-Hamoudi
    Division of Gastroenterology, Department of Pathology, Sir Mortimer B Davis Jewish General Hospital, McGill University School of Medicine, 3755 Chemin de la Cote Ste Catherine, Montreal, Quebec, Canada
    Helicobacter 11:446-50. 2006
    ..heilmannii gastritis presented as an acute febrile illness and was successfully treated with antibiotics and proton pump inhibitor. Epidemiology, diagnosis, and treatment of similar cases are reviewed...