David A Seminowicz
Affiliation: McGill University
- Interactions of pain intensity and cognitive load: the brain stays on taskDavid A Seminowicz
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Cereb Cortex 17:1412-22. 2007..These findings support the notion that brain networks supporting pain perception and cognition can be simultaneously active...
- MRI structural brain changes associated with sensory and emotional function in a rat model of long-term neuropathic painDavid A Seminowicz
Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada H3A 2B2
Neuroimage 47:1007-14. 2009..Overall, our results suggest that long-term neuropathic pain has widespread effects on brain anatomy related to the duration and magnitude of the pain...
- A re-examination of pain-cognition interactions: implications for neuroimagingDavid A Seminowicz
Institute of Medical Science, University of Toronto, Toronto, Canada
Pain 130:8-13. 2007
- Two systems of resting state connectivity between the insula and cingulate cortexKeri S Taylor
Division of Brain, Imaging and Behavior Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Canada
Hum Brain Mapp 30:2731-45. 2009....
- Nerve injury causes long-term attentional deficits in ratsLucie A Low
Alan Edwards Centre for Research on Pain, McGill University, Canada Faculty of Dentistry, McGill University, Canada Room M 19, Strathcona Anatomy and Dentistry Building, 3640 University Street, McGill University, Montreal, Quebec, Canada H3A 0C7 Electronic address
Neurosci Lett 529:103-7. 2012....
- Pain enhances functional connectivity of a brain network evoked by performance of a cognitive taskDavid A Seminowicz
University of Toronto, Ontario M5T 2S8, Canada
J Neurophysiol 97:3651-9. 2007..These data provide evidence that pain can modulate a network presumed to be involved in focused attention, suggesting a mechanism for the interference of pain on cognitive ability by the consumption of attentional resources...
- Regional gray matter density changes in brains of patients with irritable bowel syndromeDavid A Seminowicz
Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada
Gastroenterology 139:48-57.e2. 2010..Several studies have examined structural brain changes associated with chronic pain syndromes, including irritable bowel syndrome (IBS), but study sample sizes have been small and heterogeneous...
- Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and functionDavid A Seminowicz
Alan Edwards Centre for Research on Pain, McGill Scoliosis and Spine Research Group, McGill University, Montreal, Quebec H3A 1A4, Canada
J Neurosci 31:7540-50. 2011..These data indicate that functional and structural brain abnormalities-specifically in the left DLPFC-are reversible, suggesting that treating chronic pain can restore normal brain function in humans...
- The anatomy of the mesolimbic reward system: a link between personality and the placebo analgesic responsePetra Schweinhardt
Alan Edwards Centre for Research on Pain, Faculty of Dentistry, McGill University, Montreal, Quebec, Canada H3A2B2
J Neurosci 29:4882-7. 2009..Our findings highlight the relationship between placebo and reward and potentially offer ways of identifying subjects who are likely to show large placebo analgesic responses...
- Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?Anil Kuchinad
McGill Centre for Research on Pain, McGill University, Montreal, Quebec, Canada H3A 2B2
J Neurosci 27:4004-7. 2007..Moreover, the regions in which we demonstrate objective changes may be functionally linked to core features of the disorder including affective disturbances and chronic widespread pain...
- Believe in your placeboDavid A Seminowicz
Institute of Medical Science, University of Toronto, Ontario, M5T 2S8, Canada
J Neurosci 26:4453-4. 2006
- Cortical responses to pain in healthy individuals depends on pain catastrophizingDavid A Seminowicz
Toronto Western Research Institute, University Health Network, Institute of Medical Science and Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Pain 120:297-306. 2006..These findings may also implicate catastrophizing in the progression to or persistence of chronic pain...