J P Routy

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. doi request reprint Design and implementation of a randomized crossover study of valproic acid and antiretroviral therapy to reduce the HIV reservoir
    J P Routy
    McGill University Health Centre, Montreal, Quebec, Canada
    HIV Clin Trials 13:301-7. 2012
  2. doi request reprint Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study
    J P Routy
    Division of Hematology, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada
    HIV Med 13:291-6. 2012
  3. doi request reprint Assessing risk of a short-term antiretroviral therapy discontinuation as a read-out of viral control in immune-based therapy
    J P Routy
    Chronic Viral Illness Service and Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada
    J Med Virol 84:885-9. 2012
  4. ncbi request reprint Influence of RANTES, SDF-1 and TGF-beta levels on the value of interleukin-7 as a predictor of virological response in HIV-1-infected patients receiving double boosted protease inhibitor-based therapy
    M R Boulassel
    Immunodeficiency Service, Montreal Chest Institute, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    HIV Med 6:268-77. 2005
  5. doi request reprint Episomal and integrated human papillomavirus type 16 loads and anal intraepithelial neoplasia in HIV-seropositive men
    Jennifer Alvarez
    Départements de Microbiologie et Infectiologie, Pathologie, et Laboratoire de Virologie Moléculaire, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    AIDS 24:2355-63. 2010
  6. ncbi request reprint Effects of drug resistance on viral load in patients failing antiretroviral therapy
    N Machouf
    Clinique Médicale l Actuel, Montreal, Quebec, Canada
    J Med Virol 78:608-13. 2006
  7. doi request reprint A novel and simplified method of culture of human blood-derived early endothelial progenitor cells for the treatment of ischemic vascular disease
    M Bouchentouf
    Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Cell Transplant 20:1431-43. 2011
  8. ncbi request reprint Comparison of clinical features of acute HIV-1 infection in patients infected sexually or through injection drug use. The Investigators of the Québec Primary HIV Infection Study
    J P Routy
    McGill University Health Centre, McGill AIDS Centre, and McGill University, Montreal, Quebec, Canada
    J Acquir Immune Defic Syndr 24:425-32. 2000
  9. ncbi request reprint Improvement of HIV-specific immunity in HIV-infected twins treated with highly active antiretroviral therapy, interleukin 2, and syngeneic adoptively transferred cells
    C M Tsoukas
    Immunodeficiency Treatment Centre, McGill University Health Centre, Montreal General Hospital, Montreal, Quebec, Canada
    AIDS Res Hum Retroviruses 17:887-900. 2001
  10. pmc Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Ralpha on central and effector memory CD4+ and CD8+ T cell subsets
    F Mercier
    Immunodeficiency Service, Montreal Chest Institute, Montreal, Quebec, Canada
    Clin Exp Immunol 152:72-80. 2008

Collaborators

Detail Information

Publications17

  1. doi request reprint Design and implementation of a randomized crossover study of valproic acid and antiretroviral therapy to reduce the HIV reservoir
    J P Routy
    McGill University Health Centre, Montreal, Quebec, Canada
    HIV Clin Trials 13:301-7. 2012
    ..Previous pilot studies using VPA have showed conflicting results on the ability of VPA to reduce the size of HIV reservoirs...
  2. doi request reprint Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study
    J P Routy
    Division of Hematology, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada
    HIV Med 13:291-6. 2012
    ..In a randomized multicentre, cross-over study, we assessed whether adding VPA to stable HAART could potentially reduce the size of the latent viral reservoir in CD4 T cells of chronically infected patients...
  3. doi request reprint Assessing risk of a short-term antiretroviral therapy discontinuation as a read-out of viral control in immune-based therapy
    J P Routy
    Chronic Viral Illness Service and Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada
    J Med Virol 84:885-9. 2012
    ....
  4. ncbi request reprint Influence of RANTES, SDF-1 and TGF-beta levels on the value of interleukin-7 as a predictor of virological response in HIV-1-infected patients receiving double boosted protease inhibitor-based therapy
    M R Boulassel
    Immunodeficiency Service, Montreal Chest Institute, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    HIV Med 6:268-77. 2005
    ..Here, we examine associations among circulating levels of IL-7, RANTES, SDF-1 and TGF-beta in hopes of gaining insight into their contribution to the predictive value of IL-7...
  5. doi request reprint Episomal and integrated human papillomavirus type 16 loads and anal intraepithelial neoplasia in HIV-seropositive men
    Jennifer Alvarez
    Départements de Microbiologie et Infectiologie, Pathologie, et Laboratoire de Virologie Moléculaire, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    AIDS 24:2355-63. 2010
    ....
  6. ncbi request reprint Effects of drug resistance on viral load in patients failing antiretroviral therapy
    N Machouf
    Clinique Médicale l Actuel, Montreal, Quebec, Canada
    J Med Virol 78:608-13. 2006
    ..Together, these findings suggest that long-term maintenance of a sub-optimal antiretroviral regimen may have deleterious consequences for the patient...
  7. doi request reprint A novel and simplified method of culture of human blood-derived early endothelial progenitor cells for the treatment of ischemic vascular disease
    M Bouchentouf
    Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Cell Transplant 20:1431-43. 2011
    ....
  8. ncbi request reprint Comparison of clinical features of acute HIV-1 infection in patients infected sexually or through injection drug use. The Investigators of the Québec Primary HIV Infection Study
    J P Routy
    McGill University Health Centre, McGill AIDS Centre, and McGill University, Montreal, Quebec, Canada
    J Acquir Immune Defic Syndr 24:425-32. 2000
    ..Our study results clearly indicate that health care workers can expect similar clinical presentation of AHI in MSM and in IDUs despite the different routes of infection...
  9. ncbi request reprint Improvement of HIV-specific immunity in HIV-infected twins treated with highly active antiretroviral therapy, interleukin 2, and syngeneic adoptively transferred cells
    C M Tsoukas
    Immunodeficiency Treatment Centre, McGill University Health Centre, Montreal General Hospital, Montreal, Quebec, Canada
    AIDS Res Hum Retroviruses 17:887-900. 2001
    ....
  10. pmc Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Ralpha on central and effector memory CD4+ and CD8+ T cell subsets
    F Mercier
    Immunodeficiency Service, Montreal Chest Institute, Montreal, Quebec, Canada
    Clin Exp Immunol 152:72-80. 2008
    ..Collectively, these results provide further insight on the role of unsuppressed viral load in disrupting the IL-7/IL-7Ralpha system and contributing to HIV-1 disease progression...
  11. ncbi request reprint Interleukin-7 levels may predict virological response in advanced HIV-1-infected patients receiving lopinavir/ritonavir-based therapy
    M R Boulassel
    Immunodeficiency Service Division of Hematology, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    HIV Med 4:315-20. 2003
    ....
  12. ncbi request reprint Plasmapheresis in the treatment of an acute pancreatitis due to protease inhibitor-induced hypertriglyceridemia
    J P Routy
    Division of Hematology, McGill University Health Centre, Montreal, Quebec, USA
    J Clin Apher 16:157-9. 2001
    ..To our knowledge, this is the first case of pancreatitis due to a PI-induced hyperlipidemia in a HIV-patient treated with plasmapheresis in an acute setting...
  13. ncbi request reprint Rationale for maintenance of the M184v resistance mutation in human immunodeficiency virus type 1 reverse transcriptase in treatment experienced patients
    D Turner
    McGill University AIDS Centre, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada
    New Microbiol 27:31-9. 2004
    ..Collectively, these factors might explain the residual antiviral effect and clinical benefit observed with continued use of 3TC in combination therapy regimens following the emergence of M184V...
  14. ncbi request reprint Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection
    G Alter
    McGill University Health Center, Montreal, Quebec, Canada
    J Immunol 171:477-88. 2003
    ..Our results show that HIV-specific immunity can be preserved even if HAART is initiated beyond the acute phase of infection...
  15. ncbi request reprint Early lymphocyte recovery following autologous peripheral stem cell transplantation is associated with better survival in younger patients with lymphoproliferative disorders
    M R Boulassel
    Division of Hematology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Que, H3A 1A1 Canada
    Hematology 11:165-70. 2006
    ..A shorter time from diagnosis to APSCT may favor recovery of ALC independent of the infused stem cell or lymphocyte doses...
  16. doi request reprint Prevalence, clearance, and incidence of anal human papillomavirus infection in HIV-infected men: the HIPVIRG cohort study
    Alexandra de Pokomandy
    Departement De Microbiologie et Infectiologie, Hôpital Notre Dame du Centre Hospitalier de l Université de Montréal, département de médecine familiale, Faculte de Medecine, Universite de Montreal, Montreal, Quebec, Canada
    J Infect Dis 199:965-73. 2009
    ..This study was conducted to better understand the natural history of type-specific HPV infection in the anus...
  17. doi request reprint Monocyte derivatives promote angiogenesis and myocyte survival in a model of myocardial infarction
    M Bouchentouf
    Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Cell Transplant 19:369-86. 2010
    ..Transplanted MDs and their secretome participate in preserving functional myocardium after ischemic insult and attenuate pathological remodeling...