Affiliation: McGill University
- Chronic kidney disease in lithium-treated older adults: a review of epidemiology, mechanisms, and implications for the treatment of late-life mood disordersSoham Rej
Division of Geriatric Psychiatry, Department of Psychiatry, University of Toronto, Toronto, ON, Canada
Drugs Aging 32:31-42. 2015....
- Lithium dosing and serum concentrations across the age spectrum: from early adulthood to the tenth decade of lifeSoham Rej
Department of Psychiatry, McGill University, Irving Ludmer Research and Training Building, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada
Drugs Aging 31:911-6. 2014..Little is known about how lithium should be dosed to achieve therapeutic but safe serum concentrations in older adults. In this paper, we investigate how the lithium dose-concentration ratio changes across the lifespan...
- Prevalence and correlates of renal disease in older lithium users: a population-based studySoham Rej
Department of Psychiatry, McGill University, Montreal, Quebec, Canada Electronic address
Am J Geriatr Psychiatry 22:1075-82. 2014..Because high-quality evidence examining renal disease in this population is lacking, this study aims to quantify the prevalence and identify clinical correlates of renal disease in geriatric lithium users...
- Do Antidepressants Lower the Prevalence of Lithium-associated Hypernatremia in the Elderly? A Retrospective StudySoham Rej
Department of Psychiatry, McGill University, Montreal
Can Geriatr J 16:38-42. 2013..We hypothesized that antidepressant use, which has been associated with the syndrome of inappropriate antidiuretic hormone secretion, has a protective effect against lithium-associated hypernatremia in the elderly...
- Chronic renal failure in lithium-using geriatric patients: effects of lithium continuation versus discontinuation--a 60-month retrospective studySoham Rej
Department of Psychiatry, McGill University, Montreal, Canada
Int J Geriatr Psychiatry 28:450-3. 2013..We hypothesize that in geriatric patients with chronic renal failure (CRF), who have a high burden of medical illness, lithium continuation does not significantly impact renal function (glomerular filtration rate (eGFR))...
- The effect of serum lithium levels on renal function in geriatric outpatients: a retrospective longitudinal studySoham Rej
Department of Psychiatry, McGill University, Irving Ludmer Research and Training Building, 1033 Pine Avenue West, Montreal, H3A 1A1, Canada
Drugs Aging 30:409-15. 2013..Previous consensus opinion was that levels should be kept below 0.6 mmol/L in geriatric patients to minimize renal toxicity...
- Using hypernatraemic events to predict reduced renal function in elderly lithium patients: a brief reportSoham Rej
Department of Psychiatry, McGill University, Montreal, Quebec, Canada
Psychogeriatrics 13:25-8. 2013..We hypothesize that hypernatraemic events that occur in DI predict decreased renal function in elderly patients on lithium...
- The McGill Geriatric Lithium-Induced Diabetes Insipidus Clinical Study (McGLIDICS)Soham Rej
Resident, Department of Psychiatry, McGill University, Montreal, Quebec
Can J Psychiatry 59:327-34. 2014..We also assessed NDI symptoms, serum sodium (Na+), and urine specific gravity (USG) as possible surrogate measures of decreased UOsm, and ascertained whether potential etiologic factors independently correlated with decreased UOsm...
- Is environmental temperature related to renal symptoms, serum lithium levels, and other laboratory test results in current lithium users?Soham Rej
Department of Psychiatry, McGill University, Montreal, QC, Canada
Hum Psychopharmacol 29:392-6. 2014..In addition, no study has assessed the association between temperature and other renal laboratory tests and symptoms in lithium users...
- The effects of lithium on renal function in older adults--a systematic reviewSoham Rej
Psychiatry Resident, McGill University, Montreal, QC, Canada
J Geriatr Psychiatry Neurol 25:51-61. 2012..Currently, there is no compelling evidence to suggest that lithium should be avoided in elderly patients for fear of renal side effects...
- Diabetes mellitus onset in geriatric patients: does long-term atypical antipsychotic exposure increase risk?Roza Abitbol
Faculty of Medicine, Laval University, Laval, Quebec, Canada
Psychogeriatrics 15:43-50. 2015..However, it remains largely unknown whether there is an additional risk of diabetes mellitus (DM) in elderly psychiatric outpatients, particularly those with long-term exposure to atypical antipsychotics (AP)...
- Renal function in geriatric psychiatry patients compared to non-psychiatric older adults: effects of lithium use and other factorsSoham Rej
a Department of Psychiatry, McGill University, Montreal, Canada
Aging Ment Health 18:847-53. 2014..We wished to verify whether geriatric psychiatry patients are at increased risk of renal dysfunction compared to elderly controls, as well as whether lithium exposure and other factors are important predictors of risk...
- Development of central diabetes insipidus following electroconvulsive therapy: results of a prospective pilot studySoumia Imène Senouci
McGill University, Montreal, Quebec, Canada
J ECT 29:e29-30. 2013..The objective of this study was to examine the occurrence of laboratory abnormalities and symptoms of central diabetes insipidus (CDI) in patients receiving acute electroconvulsive therapy (ECT) series...
- Serotonergic antidepressants and perioperative bleeding risk: a systematic reviewArtin A Mahdanian
McGill University, Jewish General Hospital, Department of Psychiatry, Montreal, Canada
Expert Opin Drug Saf 13:695-704. 2014..Our main objective was to synthesize the current evidence to evaluate the clinical importance of SAd-related bleeding risk in the perioperative period...