Ronald B Postuma

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Environmental risk factors for REM sleep behavior disorder: a multicenter case-control study
    R B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada
    Neurology 79:428-34. 2012
  2. ncbi request reprint Prodromal Parkinson's disease--using REM sleep behavior disorder as a window
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada Electronic address
    Parkinsonism Relat Disord 20:S1-4. 2014
  3. pmc A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 27:913-6. 2012
  4. doi request reprint Brain perfusion anomalies in rapid eye movement sleep behavior disorder with mild cognitive impairment
    Melanie Vendette
    Center for Advanced Research in Sleep Medicine, Hopital du Sacre Coeur de Montreal, Quebec, Canada
    Mov Disord 27:1255-61. 2012
  5. doi request reprint Rapid eye movement sleep behavior disorder and subtypes of Parkinson's disease
    Silvia Rios Romenets
    Department of Neurology, McGill University, Montreal General Hospital, 1650 Cedar Avenue, Montreal, Quebec, Canada
    Mov Disord 27:996-1003. 2012
  6. doi request reprint Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease
    Jean Francois Gagnon
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Montreal, Quebec, Canada
    Ann Neurol 66:39-47. 2009
  7. doi request reprint Rapid eye movement sleep behavior disorder and risk of dementia in Parkinson's disease: a prospective study
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 27:720-6. 2012
  8. ncbi request reprint Electroencephalogram slowing in rapid eye movement sleep behavior disorder is associated with mild cognitive impairment
    Jessica Rodrigues Brazète
    Center for Advanced Research in Sleep Medicine, Hôpital du Sacré Cœur de Montréal, Montreal, Quebec, Canada Department of Psychology, Universite de Montreal, Montreal, Quebec, Canada
    Sleep Med 14:1059-63. 2013
  9. doi request reprint The Montreal Cognitive Assessment: a screening tool for mild cognitive impairment in REM sleep behavior disorder
    Jean Francois Gagnon
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Montreal, Quebec, Canada
    Mov Disord 25:936-40. 2010
  10. doi request reprint Idiopathic REM sleep behavior disorder in the transition to degenerative disease
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 24:2225-32. 2009

Collaborators

Detail Information

Publications34

  1. pmc Environmental risk factors for REM sleep behavior disorder: a multicenter case-control study
    R B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada
    Neurology 79:428-34. 2012
    ..Since risk factors have not been defined, we initiated a multicenter case-control study to assess environmental and lifestyle risk factors for REM sleep behavior disorder...
  2. ncbi request reprint Prodromal Parkinson's disease--using REM sleep behavior disorder as a window
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada Electronic address
    Parkinsonism Relat Disord 20:S1-4. 2014
    ..The evidence for RBD as a marker of prodromal PD and all these implications will be discussed. ..
  3. pmc A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 27:913-6. 2012
    ..Therefore, we designed the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q), a screening question for dream enactment with a simple yes/no response...
  4. doi request reprint Brain perfusion anomalies in rapid eye movement sleep behavior disorder with mild cognitive impairment
    Melanie Vendette
    Center for Advanced Research in Sleep Medicine, Hopital du Sacre Coeur de Montreal, Quebec, Canada
    Mov Disord 27:1255-61. 2012
    ..This suggests the presence of an identifiable neuroimaging marker of synucleinopathy in REM sleep behavior disorder with mild cognitive impairment. © 2012 Movement Disorder Society...
  5. doi request reprint Rapid eye movement sleep behavior disorder and subtypes of Parkinson's disease
    Silvia Rios Romenets
    Department of Neurology, McGill University, Montreal General Hospital, 1650 Cedar Avenue, Montreal, Quebec, Canada
    Mov Disord 27:996-1003. 2012
    ..009). Our results support previous findings that RBD is a multifaceted phenomenon in PD. Patients with PD who have RBD tend to have specific motor and nonmotor manifestations, especially orthostatic hypotension...
  6. doi request reprint Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease
    Jean Francois Gagnon
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Montreal, Quebec, Canada
    Ann Neurol 66:39-47. 2009
    ..To investigate the frequency and subtypes of mild cognitive impairment (MCI) in idiopathic rapid eye movement sleep behavior disorder (RBD) and Parkinson's disease (PD) in association with RBD...
  7. doi request reprint Rapid eye movement sleep behavior disorder and risk of dementia in Parkinson's disease: a prospective study
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 27:720-6. 2012
    ..In this prospective study, RBD was associated with increased risk of dementia. This indicates that RBD may be a marker of a relatively diffuse, complex subtype of PD...
  8. ncbi request reprint Electroencephalogram slowing in rapid eye movement sleep behavior disorder is associated with mild cognitive impairment
    Jessica Rodrigues Brazète
    Center for Advanced Research in Sleep Medicine, Hôpital du Sacré Cœur de Montréal, Montreal, Quebec, Canada Department of Psychology, Universite de Montreal, Montreal, Quebec, Canada
    Sleep Med 14:1059-63. 2013
    ..Moreover, approximately 50% of iRBD patients have mild cognitive impairment (MCI). The purpose of our study was to investigate waking electroencephalogram (EEG) abnormalities specific to iRBD patients with MCI...
  9. doi request reprint The Montreal Cognitive Assessment: a screening tool for mild cognitive impairment in REM sleep behavior disorder
    Jean Francois Gagnon
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Montreal, Quebec, Canada
    Mov Disord 25:936-40. 2010
    ..The MoCA is superior to the MMSE in detecting MCI in idiopathic RBD patients, showing good sensitivity and very good specificity...
  10. doi request reprint Idiopathic REM sleep behavior disorder in the transition to degenerative disease
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 24:2225-32. 2009
    ..The indistinguishability of dementia and PD in all ancillary measures suggests a single unitary "RBD-then-neurodegeneration" process, the clinical presentation of which depends upon selective neuronal vulnerability...
  11. doi request reprint Cardiac autonomic denervation in Parkinson's disease is linked to REM sleep behavior disorder
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 26:1529-33. 2011
    ..In this study we examined the relationship between rapid eye movement sleep behavior disorder and autonomic dysfunction in Parkinson's disease as measured by cardiac beat-to-beat variability...
  12. ncbi request reprint Brain perfusion and markers of neurodegeneration in rapid eye movement sleep behavior disorder
    Melanie Vendette
    Centre d Études Avancées en Médecine du Sommeil, Hôpital du Sacré Cœur de Montréal, and Department of Psychology, University of Montreal, Montreal, Quebec, Canada
    Mov Disord 26:1717-24. 2011
    ..Moreover, regional cerebral blood flow anomalies were associated with markers of neurodegeneration...
  13. doi request reprint Olfaction and color vision identify impending neurodegeneration in rapid eye movement sleep behavior disorder
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Ann Neurol 69:811-8. 2011
    ....
  14. doi request reprint REM sleep behavior disorder: from dreams to neurodegeneration
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Neurobiol Dis 46:553-8. 2012
    ....
  15. doi request reprint Manifestations of Parkinson disease differ in association with REM sleep behavior disorder
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 23:1665-72. 2008
    ..These findings suggest that the pathophysiology of RBD and nonmotor manifestations of PD, particularly autonomic dysfunction, are linked...
  16. pmc Comorbidity and medication in REM sleep behavior disorder: a multicenter case-control study
    Birgit Frauscher
    From the Department of Neurology B F, D G, T M, B H, Innsbruck Medical University, Austria Danish Center for Sleep Medicine P J, University of Copenhagen, Denmark Department of Neurology Y E S J, Washington University School of Medicine, St Louis, MO Department of Neurology R B P, McGill University, Montreal General Hospital, Canada Unité des Pathologies du Sommeil I A, S L S, Hopital Pitie Salpetriere, APHP, and Inserm U975 CRICM Pierre and Marie Curie University, Paris Sleep Unit V C D C, Y D, Department of Neurology, Hopital Gui de Chauliac, Montpellier, Inserm U1061, Montpellier, France Sleep Disorders Center M L F, Department of Neurosciences, University of Turin, Italy UFR Medecine M L F, EA 7280, University Clermont 1, France Sleep Disorders Center L F S, M Z, Universita Vita Salute San Raffaele, Milan, Italy Neurology Service A I, J S, Hospital Clinic de Barcelona
    Neurology 82:1076-9. 2014
    ..This controlled study investigated associations between comorbidity and medication in patients with polysomnographically confirmed idiopathic REM sleep behavior disorder (iRBD), using a large multicenter clinic-based cohort...
  17. doi request reprint Cardiac autonomic dysfunction in idiopathic REM sleep behavior disorder
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 25:2304-10. 2010
    ..This suggests that autonomic dysfunction is linked with RBD independent of associated Parkinson's disease or Lewy body dementia...
  18. doi request reprint Abnormal occipital event-related potentials in Parkinson's disease with concomitant REM sleep behavior disorder
    Pierre Olivier Gaudreault
    Center for Advanced Research in Sleep Medicine, Hôpital du Sacré Cœur de Montréal, Montreal, QC, Canada
    Parkinsonism Relat Disord 19:212-7. 2013
    ..Our goal was to improve our understanding of the role of this sleep disorder in cerebral dysfunction occurring in Parkinson's disease using a visual cognitive task and event-related potentials...
  19. pmc Caffeine for treatment of Parkinson disease: a randomized controlled trial
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada
    Neurology 79:651-8. 2012
    ..Epidemiologic studies consistently link caffeine, a nonselective adenosine antagonist, to lower risk of Parkinson disease (PD). However, the symptomatic effects of caffeine in PD have not been adequately evaluated...
  20. doi request reprint Prodromal autonomic symptoms and signs in Parkinson's disease and dementia with Lewy bodies
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 28:597-604. 2013
    ..2013 Movement Disorder Society...
  21. doi request reprint Validity of the Mattis Dementia Rating Scale to detect mild cognitive impairment in Parkinson's disease and REM sleep behavior disorder
    Sylvia Villeneuve
    Departement de Psychologie, Universite de Montreal, Montreal, Quebec, Canada
    Dement Geriatr Cogn Disord 31:210-7. 2011
    ..Our aim was to evaluate the validity of the Mini-Mental State Examination (MMSE) and the Mattis Dementia Rating Scale (DRS-2) to detect MCI in PD and iRBD...
  22. doi request reprint Rapid eye movement sleep behavior disorder as a biomarker for neurodegeneration: the past 10 years
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Sleep Med 14:763-7. 2013
    ....
  23. pmc Antidepressants and REM sleep behavior disorder: isolated side effect or neurodegenerative signal?
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada Centre d Études Avancées en Médecine du Sommeil, Hôpital du Sacré Cœur de Montréal, Montreal, Quebec, Canada
    Sleep 36:1579-85. 2013
    ..It is therefore critically important to understand whether antidepressant-associated RBD is an independent pharmacologic syndrome or a sign of possible prodromal neurodegeneration...
  24. doi request reprint Polysomnographic diagnosis of idiopathic REM sleep behavior disorder
    Jacques Montplaisir
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Quebec, Canada
    Mov Disord 25:2044-51. 2010
    ..For the five RBD patients who did not show chin EMG abnormalities, it cannot be excluded that they had increased phasic EMG activity in the upper limbs and presented visible motor activity...
  25. doi request reprint Caffeine in Parkinson's disease: a pilot open-label, dose-escalation study
    Robert D Altman
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 26:2427-31. 2011
    ..Epidemiologic studies consistently find an inverse association between caffeine use and PD. Numerous explanations exist, but are difficult to evaluate as caffeine's symptomatic effect and tolerability in PD are unknown...
  26. doi request reprint Color discrimination deficits in Parkinson's disease are related to cognitive impairment and white-matter alterations
    Josie Anne Bertrand
    Center for Advanced Research in Sleep Medicine, Sacre Coeur Hospital, Montreal, Quebec, Canada
    Mov Disord 27:1781-8. 2012
    ..Poor performance on the Farnsworth-Munsell 100 hue test was also associated with white-matter alterations in right posterior brain regions...
  27. ncbi request reprint Is there seasonal variation in risk of Parkinson's disease?
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 22:1097-101. 2007
    ..We found no evidence of systematic seasonal variation in PD incidence by birth date, or of clustering of birth dates during influenza pandemic years in PD patients...
  28. ncbi request reprint Update on the pharmacology of REM sleep behavior disorder
    Jean Francois Gagnon
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Institut Universitaire de Geriatrie de Montreal, Montreal, Quebec, Canada
    Neurology 67:742-7. 2006
    ..When these agents are prescribed to patients with neurodegenerative disorders or narcolepsy who are at risk of developing RBD, systematic follow-up may be warranted to detect the emergence of RBD symptoms...
  29. doi request reprint Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's disease
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 27:617-26. 2012
    ..The evidence for the utility of olfaction, RBD, autonomic markers, visual changes, mood disorders, and cognitive loss as markers of prodromal PD and the potential sensitivity and specificity of these markers are summarized...
  30. ncbi request reprint Potential early markers of Parkinson disease in idiopathic REM sleep behavior disorder
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Neurology 66:845-51. 2006
    ..Several potential early diagnostic markers of PD have been proposed, but they have generally not been tested in presymptomatic PD. The authors hypothesized that these markers may be abnormal in idiopathic RBD...
  31. ncbi request reprint Rapid-eye-movement sleep behaviour disorder and neurodegenerative diseases
    Jean Francois Gagnon
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Quebec, Canada
    Lancet Neurol 5:424-32. 2006
    ..RBD might be a stage in the development of neurodegenerative disorders and increased awareness of this could lead to substantial advances in knowledge of mechanisms, diagnosis, and treatment of neurodegenerative disorders...
  32. doi request reprint Is there a higher risk of restless legs syndrome in peripheral neuropathy?
    Erin Hattan
    Department of Neurology and Neurosurgery, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Neurology 72:955-60. 2009
    ..If RLS prevalence is truly increased by neuropathy, this has important implications for RLS pathophysiology...
  33. ncbi request reprint Does severity of Parkinson's disease vary according to season?
    Ronald B Postuma
    Department of Neurology, McGill University, Montreal General Hospital, Montreal, Quebec, Canada
    Mov Disord 20:476-9. 2005
    ..We found no evidence for seasonal fluctuation in the UPDRS scores, suggesting that, although considerable day-to-day variation may exist in PD, there is little monthly or seasonal variation...