Louise Pilote

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada
    Raluca Ionescu-Ittu
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada
    BMJ 338:b1673. 2009
  2. doi request reprint Temporal trends in medication use and outcomes in atrial fibrillation
    Louise Pilote
    Division of General Internal Medicine, McGill University Health Centre, Montreal, Quebec, Canada Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada Electronic address
    Can J Cardiol 29:1241-8. 2013
  3. pmc Risk factors, quality of care and prognosis in South Asian, East Asian and White patients with stroke
    Nadia A Khan
    Department of Medicine, University of British Columbia, 620 B, 1081 Burrard Street, St, Paul s Hospita, Vancouver, BC V6Z 1Y6, Canada
    BMC Neurol 13:74. 2013
  4. doi request reprint GENESIS-PRAXY (GENdEr and Sex determInantS of cardiovascular disease: From bench to beyond-Premature Acute Coronary SYndrome)
    Louise Pilote
    Division of General Internal Medicine, McGill University Health Centre, 687 Pine Avenue West, Montreal, Quebec, Canada
    Am Heart J 163:741-746.e2. 2012
  5. pmc Walking behaviour and glycemic control in type 2 diabetes: seasonal and gender differences--study design and methods
    Kaberi Dasgupta
    Department of Medicine, Division of Clinical Epidemiology, McGill University Health Centre, 687 Pine Avenue West, Montreal, Canada
    Cardiovasc Diabetol 6:1. 2007
  6. pmc Comparison of nested case-control and survival analysis methodologies for analysis of time-dependent exposure
    Vidal Essebag
    Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
    BMC Med Res Methodol 5:5. 2005
  7. pmc The interpretation of systematic reviews with meta-analyses: an objective or subjective process?
    Ian Shrier
    Centre for Clinical Epidemiology and Community Studies, Lady Davis Institute for Medical Research, SMBD Jewish General Hospital, McGill University, Montreal, Canada
    BMC Med Inform Decis Mak 8:19. 2008
  8. pmc The research on endothelial function in women and men at risk for cardiovascular disease (REWARD) study: methodology
    Simon L Bacon
    Montreal Behavioural Medicine Centre, Montreal, Canada
    BMC Cardiovasc Disord 11:50. 2011
  9. ncbi request reprint Secondary prevention after acute myocardial infarction in four Canadian provinces, 1997-2000
    Louise Pilote
    McGill University Health Centre, Montreal General Hospital Research Institute, Montreal, Quebec, Canada
    Can J Cardiol 20:61-7. 2004
  10. pmc Outcomes research in the development and evaluation of practice guidelines
    Louise Pilote
    Division of Clinical Epidemiology, Research Institute of the McGill University Health Center, Montreal, Canada
    BMC Health Serv Res 2:7. 2002

Detail Information

Publications106 found, 100 shown here

  1. pmc Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada
    Raluca Ionescu-Ittu
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada
    BMJ 338:b1673. 2009
    ..To investigate whether the 1998 government policy for mandatory fortification of flour and pasta products with folate was followed by a reduction in the prevalence of severe congenital heart defects...
  2. doi request reprint Temporal trends in medication use and outcomes in atrial fibrillation
    Louise Pilote
    Division of General Internal Medicine, McGill University Health Centre, Montreal, Quebec, Canada Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada Electronic address
    Can J Cardiol 29:1241-8. 2013
    ..To best evaluate the comparative effectiveness of newer agents, practice patterns and outcomes of existing therapies must be characterized at the population level...
  3. pmc Risk factors, quality of care and prognosis in South Asian, East Asian and White patients with stroke
    Nadia A Khan
    Department of Medicine, University of British Columbia, 620 B, 1081 Burrard Street, St, Paul s Hospita, Vancouver, BC V6Z 1Y6, Canada
    BMC Neurol 13:74. 2013
    ..We compared risk factors, quality of care and risk of death or recurrent stroke in South Asian, East Asian and White patients with acute ischemic and hemorrhagic stroke...
  4. doi request reprint GENESIS-PRAXY (GENdEr and Sex determInantS of cardiovascular disease: From bench to beyond-Premature Acute Coronary SYndrome)
    Louise Pilote
    Division of General Internal Medicine, McGill University Health Centre, 687 Pine Avenue West, Montreal, Quebec, Canada
    Am Heart J 163:741-746.e2. 2012
    ..This study will investigate the clinical presentation, prognosis, and health care use in young men and women with ACS...
  5. pmc Walking behaviour and glycemic control in type 2 diabetes: seasonal and gender differences--study design and methods
    Kaberi Dasgupta
    Department of Medicine, Division of Clinical Epidemiology, McGill University Health Centre, 687 Pine Avenue West, Montreal, Canada
    Cardiovasc Diabetol 6:1. 2007
    ..Among Canadians with type 2 diabetes, we postulate that declines in walking associated with colder temperatures and inclement weather may contribute to annual post-winter increases in A1C levels...
  6. pmc Comparison of nested case-control and survival analysis methodologies for analysis of time-dependent exposure
    Vidal Essebag
    Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
    BMC Med Res Methodol 5:5. 2005
    ..This study compares a nested case-control approach for the study of time-dependent exposure with cohort analysis using Cox regression including time-dependent covariates...
  7. pmc The interpretation of systematic reviews with meta-analyses: an objective or subjective process?
    Ian Shrier
    Centre for Clinical Epidemiology and Community Studies, Lady Davis Institute for Medical Research, SMBD Jewish General Hospital, McGill University, Montreal, Canada
    BMC Med Inform Decis Mak 8:19. 2008
    ..The objective of this study was to determine the discordance in interpretations when meta-analysts are presented with identical data...
  8. pmc The research on endothelial function in women and men at risk for cardiovascular disease (REWARD) study: methodology
    Simon L Bacon
    Montreal Behavioural Medicine Centre, Montreal, Canada
    BMC Cardiovasc Disord 11:50. 2011
    ....
  9. ncbi request reprint Secondary prevention after acute myocardial infarction in four Canadian provinces, 1997-2000
    Louise Pilote
    McGill University Health Centre, Montreal General Hospital Research Institute, Montreal, Quebec, Canada
    Can J Cardiol 20:61-7. 2004
    ..Publication of population-based analyses of medication use after acute myocardial infarction (AMI) could encourage the use of effective secondary prevention medications...
  10. pmc Outcomes research in the development and evaluation of practice guidelines
    Louise Pilote
    Division of Clinical Epidemiology, Research Institute of the McGill University Health Center, Montreal, Canada
    BMC Health Serv Res 2:7. 2002
    ..Despite their widespread use, however, practice guideline evaluation lacks a rigorous scientific methodology to support its development and application...
  11. ncbi request reprint Cardiac procedures after an acute myocardial infarction across nine Canadian provinces
    Louise Pilote
    McGill University Health Centre at the Montreal General Hospital, Montreal, Quebec, Canada
    Can J Cardiol 20:491-500. 2004
    ..Geographical variations in the use of invasive cardiac procedures have been documented. It remains unclear to what extent these variations exist across the Canadian provinces...
  12. ncbi request reprint Mortality rates in elderly patients who take different angiotensin-converting enzyme inhibitors after acute myocardial infarction: a class effect?
    Louise Pilote
    The Montreal General Hospital, Jewish General Hospital, and McGill University, Montreal, Quebec, Canada
    Ann Intern Med 141:102-12. 2004
    ..However, existing data from trials do not address whether all ACE inhibitors benefit patients similarly...
  13. pmc The effects of cost-sharing on essential drug prescriptions, utilization of medical care and outcomes after acute myocardial infarction in elderly patients
    Louise Pilote
    Division of Internal Medicine, Montreal General Hospital Research Institute, Que
    CMAJ 167:246-52. 2002
    ..We assessed the impact of this drug policy reform on prescribing patterns for essential cardiac medications, utilization of medical care and related health outcomes after acute myocardial infarction...
  14. ncbi request reprint Comparing invasive and noninvasive management strategies for acute myocardial infarction using administrative databases
    Louise Pilote
    Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada
    Am Heart J 155:42-8. 2008
    ..The aim of this study was to compare outcomes after acute myocardial infarction between regions with low and high catheterization access...
  15. pmc A comprehensive view of sex-specific issues related to cardiovascular disease
    Louise Pilote
    Division of Internal Medicine, The McGill University Health Centre Research Institute, McGill University, Montreal, Que
    CMAJ 176:S1-44. 2007
    ..However, the interaction between sex-and gender-related factors and CVD outcomes in women remains largely unknown...
  16. ncbi request reprint Cost-effectiveness of lipid-lowering treatment according to lipid level
    Louise Pilote
    Division of Clinical Epidemiology, Montreal General Hospital Research Institute, Quebec
    Can J Cardiol 21:681-7. 2005
    ..However, the proportion of the general population for which treatment is cost-effective has not been evaluated...
  17. ncbi request reprint Universal health insurance coverage does not eliminate inequities in access to cardiac procedures after acute myocardial infarction
    Louise Pilote
    Division of Clinical Epidemiology, The Montreal General Hospital Research Institute, Montreal, Quebec, Canada
    Am Heart J 146:1030-7. 2003
    ..The objective of this study was to evaluate the effect of SES on access to cardiac procedure after AMI in a universal health care system...
  18. pmc Temporal trends in revascularization and outcomes after acute myocardial infarction among the very elderly
    Maude Pagé
    Division of Cardiology, Department of Medicine, Hopital du Sacre Coeur de Montreal, Universite de Montreal, Que
    CMAJ 182:1415-20. 2010
    ..Our objective was to describe trends in revascularization procedures and outcomes in a provincial cohort of very elderly patients who had experienced acute myocardial infarction...
  19. ncbi request reprint Cardiac procedure use and outcomes in elderly patients with acute myocardial infarction in the United States and Quebec, Canada, 1988 to 1994
    Louise Pilote
    Montreal General Hospital, Quebec, Canada
    Med Care 41:813-22. 2003
    ..Little is known about whether treatments and outcomes are changing differently over time in the two countries, and whether the differences vary with patient age...
  20. ncbi request reprint Antibiotics against Chlamydia pneumoniae and prognosis after acute myocardial infarction
    Louise Pilote
    Division of Clinical Epidemiology, McGill University Health Centre, Jewish General Hospital, Montreal, Quebec, H3G 1A4, Canada
    Am Heart J 143:294-300. 2002
    ..There is mounting pathologic and immunologic evidence that Chlamydia pneumoniae plays a role in the atherogenic pathway. However, very few clinical studies have supported these findings...
  21. pmc Ramipril use in Canada: HOPE or HYPE?
    Louise Pilote
    Division of Clinical Epidemiology, McGill University, Montreal, QC
    CMAJ 168:568-9. 2003
  22. doi request reprint Severity at entry to specialized heart failure clinics: discrepancies between health-related quality of life and function in men and women
    Debbie Ehrmann Feldman
    University of Montreal, Faculty of Medicine, School of Rehabilitation, and Public Health Department of Montreal, Montreal, Quebec, Canada
    Can J Cardiol 27:382-7. 2011
    ....
  23. ncbi request reprint Cardiac medical therapy among patients undergoing abdominal aortic aneurysm repair
    David Kurzencwyg
    Division of Cardiology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Ann Vasc Surg 20:569-76. 2006
    ..07, 95% CI 0.01-0.87, p = 0.04). Cardiac medical therapy among patients undergoing AAA repair is low throughout all periods of hospitalization. ACE inhibitor and ss-blocker use may be associated with decreased in-hospital mortality...
  24. ncbi request reprint Lack of benefit for routine functional testing early after coronary artery bypass graft surgery: results from the ROSETTA-CABG Registry
    Mark J Eisenberg
    Jewish General Hospital McGill University, Montreal, Quebec, Canada
    J Invasive Cardiol 18:147-52. 2006
    ..There is little consensus regarding the use of functional testing after coronary artery bypass graft surgery (CABG). Some physicians opt for a routine functional testing strategy, while others employ a symptom-driven strategy...
  25. pmc Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect
    Zheng Zhou
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Que
    CMAJ 172:1187-94. 2005
    ..However, it is unclear whether different statins exert a similar effect in reducing the incidence of recurrent AMI and death when used in clinical practice...
  26. doi request reprint Impact of restrictive prescription plans on heart failure medication use
    George Thanassoulis
    Divisions of Clinical Epidemiology, Cardiology, and Internal Medicine, McGill University Health Center, Montreal, Quebec, Canada
    Circ Cardiovasc Qual Outcomes 2:484-90. 2009
    ..Increased restrictions may reduce access to evidence-based therapy among patients with chronic disease. We sought to evaluate the impact of increased restrictions on medication use among heart failure (HF) patients...
  27. doi request reprint The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis
    Salvatore Mottillo
    Jewish General Hospital McGill University, Montreal, Quebec, Canada
    J Am Coll Cardiol 56:1113-32. 2010
    ....
  28. ncbi request reprint Routine functional testing after percutaneous coronary intervention: results of the aggressive diagnosis of restenosis in high-risk patients (ADORE II) trial
    Mark J Eisenberg
    Division of Cardiology, Jewish General Hospital McGill University, 3755 Cote Ste Catherine Road Suite A 118, Montreal, Quebec H3T 1E2, Canada
    Acta Cardiol 62:143-50. 2007
    ..It is unclear whether routine or selective functional testing is optimal following percutaneous coronary intervention (PCI) in high-risk patients...
  29. pmc Use of cardiovascular medical therapy among patients undergoing coronary artery bypass graft surgery: results from the ROSETTA-CABG registry
    Karen Okrainec
    Department of Epidemiology and Biostatistics, McGill Univeristy, Montreal, Quebec
    Can J Cardiol 22:841-7. 2006
    ..The objective of the present study is to describe the use of cardiovascular medical therapy among patients discharged after CABG surgery...
  30. doi request reprint Percent predicted value for the 6-minute walk test: using norm-referenced equations to characterize severity in persons with CHF
    Konstantin Balashov
    University of Montreal, School of Rehabilitation, Montreal, Canada
    J Card Fail 14:75-81. 2008
    ..Norm-referenced equations that predict the 6-minute walk distance (6MWD) according to age, height, weight, and gender have been proposed for healthy patients. We explored whether these equations apply to CHF patients...
  31. ncbi request reprint Impact of functional testing results on prescription patterns of anti-anginal medication after coronary artery bypass graft surgery: results from the ROSETTA-CABG Registry
    Karen Wou
    Jewish General Hospital McGill University, Center for Epidemiology and Community Studies, Suite A 118, 3755 Cote Ste Catherine, Montreal, Quebec, Canada, H3T 1E2
    J Invasive Cardiol 18:278-82. 2006
    ..However, it is unclear how functional testing results have an impact on anti-anginal medication prescription patterns...
  32. ncbi request reprint Socioeconomic status, access to health care, and outcomes after acute myocardial infarction in Canada's universal health care system
    Louise Pilote
    Division of Clinical Epidemiology, Montreal General Hospital Research Institute, McGill University Health Centre, Montreal, Quebec, Canada
    Med Care 45:638-46. 2007
    ..There is a debate as to whether universal drug coverage confers similar access to care at all socioeconomic status (SES) levels. Experiences in Canada may bring light to questions raised regarding access...
  33. ncbi request reprint Risk of congestive heart failure with nonsteroidal antiinflammatory drugs and selective Cyclooxygenase 2 inhibitors: a class effect?
    Marie Hudson
    The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Arthritis Rheum 57:516-23. 2007
    ..Nonsteroidal antiinflammatory drugs (NSAIDs) as a class have been shown to increase the risk of congestive heart failure (CHF) compared with celecoxib. The magnitude of the risk for individual NSAIDs is not known...
  34. ncbi request reprint Effect of gender on treatment, resource utilization, and outcomes in congestive heart failure in Quebec, Canada
    Richard Sheppard
    Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Am J Cardiol 95:955-9. 2005
    ..03 to 1.1, p <0.01). Thus, despite less frequent cardiologist assessment, fewer cardiac-related procedures, and less frequent use of standard medical therapy, clinical outcomes in women and men who had CHF were similar...
  35. ncbi request reprint Warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation undergoing dialysis
    Mitesh Shah
    Divisions of Clinical Epidemiology and General Internal Medicine, McGill University Health Center, Montreal, Quebec, Canada M S, M A T, NE R, H B, L P _ Department of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA C A J Division of Cardiology, McGill University Health Center, Montreal, Quebec, Canada V E Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital McGill University, Montreal, Quebec, Canada M J E Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada K H H Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Canada Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada J V T and Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada H G
    Circulation 129:1196-203. 2014
    ..Current observational studies on warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation (AF) undergoing dialysis found conflicting results...
  36. doi request reprint Depression and disease severity in patients with premature acute coronary syndrome
    Roxanne Pelletier
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Am J Med 127:87-93.e1-2. 2014
    ..We assessed whether major depression and depressive symptoms were associated with worse cardiovascular disease severity in patients with premature acute coronary syndrome, and we assessed sex differences in these relationships...
  37. ncbi request reprint Angiotensin II receptor blockers for the treatment of heart failure: a class effect?
    Marie Hudson
    Division of Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, Quebec
    Pharmacotherapy 27:526-34. 2007
    ..To examine the class effect of angiotensin II receptor blockers (ARBs) on mortality in patients with heart failure who were aged 65 years or older...
  38. pmc Amiodarone-induced thyroid dysfunction: brand-name versus generic formulations
    Meytal A Tsadok
    Division of Internal Medicine, McGill University Health Center, Montreal, Que
    CMAJ 183:E817-23. 2011
    ..We evaluated and compared the risk of thyroid dysfunction between patients using brand-name versus generic formulations of amiodarone and identified risk factors for thyroid dysfunction...
  39. doi request reprint Statins and cancer risk
    Igor Karp
    Department of Social and Preventive Medicine, University of Montreal, Quebec, Canada
    Am J Med 121:302-9. 2008
    ..The objective of this study was to investigate the relation between lipophilic statin use and cancer occurrence...
  40. ncbi request reprint Regional variation in the management of acute myocardial infarction in the province of Quebec
    Eric J Rodrigues
    Division of Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Can J Cardiol 18:1067-76. 2002
    ..However, there has been little research to evaluate regional variations in AMI treatment and outcomes for Canadian patients...
  41. doi request reprint Long-term outcomes after surgical versus transcatheter closure of atrial septal defects in adults
    Mark A Kotowycz
    McGill Adult Unit for Congenital Heart Disease Excellence, McGill University Health Centre, Montreal, Quebec, Canada
    JACC Cardiovasc Interv 6:497-503. 2013
    ..The purpose of this study was to assess the comparative effectiveness and long-term safety of transcatheter versus surgical closure of secundum atrial septal defects (ASD) in adults...
  42. ncbi request reprint Angiotensin-converting enzyme inhibitors and survival in women and men with heart failure
    Golyar Keyhan
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Centre, 1650 Cedar Avenue, Room L10 421, Montreal, QC, Canada H3G 1A4
    Eur J Heart Fail 9:594-601. 2007
    ..However, whether ACE inhibitors benefit both sexes is not adequately addressed...
  43. ncbi request reprint Specialized adult congenital heart disease care: the impact of policy on mortality
    Darren Mylotte
    McGill Adult Unit for Congenital Heart Disease, McGill University Health Centre, Montreal, Canada D M, R I I, J T, A M Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada L P, M A Division of General Internal Medicine, Department of Medicine, McGill University, Montreal, Canada L P Division of Clinical Epidemiology, Research Institute McGill University Health Center, Montreal, Canada L P, M A Department of Cardiology, Montreal Heart Institute, Universite de Montreal, Montreal, Canada P K and Stollery Children s Hospital and University of Alberta, Edmonton, Alberta, Canada A S M
    Circulation 129:1804-12. 2014
    ..Clinical guidelines recommend specialized care for adult congenital heart disease (ACHD) patients. In reality, few patients receive such dedicated care. We sought to examine the impact of specialized care on ACHD patient mortality...
  44. ncbi request reprint Utilization of evidence-based therapy for acute coronary syndrome in high-income and low/middle-income countries
    Avi Shimony
    Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada
    Am J Cardiol 113:793-7. 2014
    ..Further studies are needed to understand the underutilization of procedures and evidence-based medications in low/middle-income countries. ..
  45. doi request reprint Gender and other disparities in referral to specialized heart failure clinics following emergency department visits
    Debbie Ehrmann Feldman
    Universite de Montreal, Montreal, Quebec H3C3J7, Canada
    J Womens Health (Larchmt) 22:526-31. 2013
    ..The objective was to determine whether there were disparities for gender and other factors associated with referral of patients to specialized HF clinics...
  46. doi request reprint Diagnosis of pulmonary hypertension in the congenital heart disease adult population impact on outcomes
    Boris S Lowe
    McGill Adult Unit for Congenital Heart Disease Excellence, McGill University Health Center, Montreal, Quebec, Canada
    J Am Coll Cardiol 58:538-46. 2011
    ..The aim of this study was to assess the impact of the diagnosis of pulmonary hypertension (PH) on mortality, morbidity, and health services utilization (HSU) in an adult congenital heart disease (CHD) population...
  47. ncbi request reprint Hospital readmissions following abdominal aortic aneurysm repair
    Laura C Gioia
    Division of Cardiology, Jewish General Hospital McGill University, Montreal, Quebec, Canada
    Ann Vasc Surg 19:35-41. 2005
    ..Hospital readmissions are common during the 6 months following AAA repair. Patients who are readmitted experience long lengths of stay and high mortality rates, and their care incurs high costs...
  48. pmc Depression and prognosis following hospital admission because of acute myocardial infarction
    Claude Lauzon
    Division of Internal Medicine, Centre hospitalier de la Région de l Amiante, Thetford Mines, QC
    CMAJ 168:547-52. 2003
    ..We prospectively evaluated patients admitted to 5 tertiary care and 5 community hospitals and followed them for 1 year to measure the prevalence and prognostic impact of depressive symptoms after acute myocardial infarction...
  49. doi request reprint Rhythm versus rate control therapy and subsequent stroke or transient ischemic attack in patients with atrial fibrillation
    Meytal Avgil Tsadok
    MPH, McGill University Health Centre, 687 Pine Ave West, V Building, Montreal, Quebec, H3A 1A1 Canada
    Circulation 126:2680-7. 2012
    ....
  50. doi request reprint Sex differences in stroke risk among older patients with recently diagnosed atrial fibrillation
    Meytal Avgil Tsadok
    Division of Clinical Epidemiology, McGill University Health Center, Montreal, Quebec, Canada
    JAMA 307:1952-8. 2012
    ..Women with AF are at higher risk of stroke compared with men. Reasons for this higher stroke risk in women remain unclear, although some studies suggest that undertreatment with warfarin may be a cause...
  51. pmc Comparison of provincial prescription drug plans and the impact on patients' annual drug expenditures
    Virginie Demers
    Division of General Internal Medicine, McGill University Health Centre, Montreal, Que
    CMAJ 178:405-9. 2008
    ..Provincial governments independently establish reimbursement plans. We sought to describe variations in publicly funded provincial drug plans across Canada and to examine the impact of this variation on patients' annual expenditures...
  52. ncbi request reprint Sex differences in the effectiveness of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in patients with congestive heart failure--a population study
    Marie Hudson
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Centre, 1650 Cedar Ave, Montreal, QC, Canada
    Eur J Heart Fail 9:602-9. 2007
    ..We wish to determine whether there are sex-related differences in the optimal treatment of congestive heart failure...
  53. pmc The efficacy of smoking cessation therapies in cardiac patients: a meta-analysis of randomized controlled trials
    Mark J Eisenberg
    Division of Cardiology, Jewish General Hospital McGill University, 3755 Cote Ste Catherine Road, Montreal, Quebec, Canada
    Can J Cardiol 26:73-9. 2010
    ..Therefore, a meta-analysis of randomized controlled trials (RCTs) was performed to determine the efficacy of behavioural therapy and pharmacotherapy for smoking cessation in cardiac patients...
  54. ncbi request reprint Parabolas of medication use and discontinuation after myocardial infarction--are we closing the treatment gap?
    Marie Hudson
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Center, 687 Pine Avenue West, Building V, Montreal, Quebec, Canada
    Pharmacoepidemiol Drug Saf 16:773-85. 2007
    ....
  55. doi request reprint Class effects of statins in elderly patients with congestive heart failure: a population-based analysis
    Stephane Rinfret
    Division of Cardiology, Department of Medicine, Centre Hospitalier de l Universite de Montreal, University of Montreal, Montreal, Quebec, Canada
    Am Heart J 155:316-23. 2008
    ..Long-term treatment with statins reduces mortality in patients with congestive heart failure (CHF). Whether statin agents exert a class effect is unknown...
  56. doi request reprint Sex- and gender-related risk factor burden in patients with premature acute coronary syndrome
    Jin Choi
    Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada
    Can J Cardiol 30:109-17. 2014
    ..Few contemporary data exist on traditional (TRF) and non-TRF (NTRF) burden in patients with premature acute coronary syndrome (ACS)...
  57. ncbi request reprint Bleeding complications associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients following acute myocardial infarction
    Khaled Buresly
    McGill University Health Centre Research Institute, Jewish General Hospital, Montreal, Quebec
    Arch Intern Med 165:784-9. 2005
    ..This study estimates the bleeding risks associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients...
  58. doi request reprint Geriatric congenital heart disease: burden of disease and predictors of mortality
    Jonathan Afilalo
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    J Am Coll Cardiol 58:1509-15. 2011
    ..The study sought to measure the prevalence, disease burden, and determinants of mortality in geriatric adults with congenital heart disease (ACHD)...
  59. pmc Impact of on-site cardiac catheterization on resource utilization and fatal and non-fatal outcomes after acute myocardial infarction
    Abdul R Halabi
    Divisions of Cardiology, Montreal General Hospital, McGill University Health Center, Montreal, Canada
    BMC Health Serv Res 6:148. 2006
    ..Although the management found at hospitals without on-site catheterization does not lead to increased mortality, little it known about its impact on resource utilization and non-fatal outcomes...
  60. doi request reprint Use of perioperative cardiac medical therapy among patients undergoing coronary artery bypass graft surgery
    Kristian B Filion
    Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Montreal, Quebec, Canada
    J Card Surg 23:209-15. 2008
    ..However, the use of these agents among patients undergoing coronary artery bypass graft (CABG) remains poorly understood...
  61. pmc Pharmacotherapies for smoking cessation: a meta-analysis of randomized controlled trials
    Mark J Eisenberg
    Division of Cardiology and Clinical Epidemiology, Sir Mortimer B Davis Jewish General Hospital and McGill University, McGill University, Montreal, QC
    CMAJ 179:135-44. 2008
    ..However, few direct or indirect comparisons of such interventions have been conducted. We performed a meta-analysis to compare the treatment effects of 7 approved pharmacologic interventions for smoking cessation...
  62. ncbi request reprint The importance of indirect costs in primary cardiovascular disease prevention: can we save lives and money with statins?
    Steven A Grover
    Division of Clinical Epidemiology, The Montreal General Hospital, 1650 Cedar Ave, Montreal, Quebec, Canada H3G 1A4
    Arch Intern Med 163:333-9. 2003
    ..We compared the cost-effectiveness of lipid level modification in the primary prevention of CVD with and without these indirect costs...
  63. ncbi request reprint Outcomes and cost of coronary artery bypass graft surgery in the United States and Canada
    Mark J Eisenberg
    Division of Cardiology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Arch Intern Med 165:1506-13. 2005
    ..We sought to determine whether there is a difference in in-hospital outcomes and costs for coronary artery bypass graft surgery (CABG) between the United States and Canada...
  64. ncbi request reprint Drug prescriptions after acute myocardial infarction: dosage, compliance, and persistence
    Ewurabena Simpson
    Division of Clinical Epidemiology, Montreal General Hospital, Montreal, Quebec, Canada
    Am Heart J 145:438-44. 2003
    ..few studies have examined dosage and long-term compliance and persistence patterns for the use of these drugs after AMI...
  65. ncbi request reprint Survival bias associated with time-to-treatment initiation in drug effectiveness evaluation: a comparison of methods
    Zheng Zhou
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 162:1016-23. 2005
    ..Method 5 used a time-dependent variable for treatment initiation. Methods 4 and 5 better controlled for survival bias and yielded similar results, suggesting a 20% risk reduction of recurrent myocardial infarction or death events...
  66. doi request reprint Hospital readmissions in children with congenital heart disease: a population-based study
    Andrew S Mackie
    McGill Adult Unit for Congenital Heart Disease Excellence MAUDE Unit, Montreal, Quebec, Canada
    Am Heart J 155:577-84. 2008
    ..We sought to determine rates and risk factors for hospital readmission within 1 month among children with CHD...
  67. ncbi request reprint Health care resource utilization in adults with congenital heart disease
    Andrew S Mackie
    McGill Adult Unit for Congenital Heart Disease Excellence, Montreal, Quebec, Canada
    Am J Cardiol 99:839-43. 2007
    ..08, 95% CI 2.00 to 2.17). In conclusion, adults with CHD have high rates of health care resource utilization, particularly those with severe lesions. Appropriate resource allocation is required to serve this growing population...
  68. ncbi request reprint Coronary artery bypass graft surgery: do women cost more?
    A Bestawros
    Montreal General Hospital McGill University, Montreal, Canada
    Can J Cardiol 21:1195-200. 2005
    ..Coronary artery bypass graft surgery (CABG) in women has been associated with worse clinical outcomes than CABG in men. However, little is known about the impact of sex on the cost of CABG...
  69. ncbi request reprint Cardiac medical therapy in patients after undergoing coronary artery bypass graft surgery: a review of randomized controlled trials
    Karen Okrainec
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    J Am Coll Cardiol 45:177-84. 2005
    ..However, current data do not support the use of beta-blockers, CCBs, and nitrates, and more evidence is needed regarding the use of ACE inhibitors...
  70. doi request reprint Sex differences in acute coronary syndrome symptom presentation in young patients
    Nadia A Khan
    Department of Medicine, Center for Health Evaluation and Outcomes Science, University of British Columbia, Vancouver, British Columbia, Canada
    JAMA Intern Med 173:1863-71. 2013
    ..Little is known about whether sex differences in acute coronary syndrome (ACS) presentation exist in young patients and what factors determine absence of chest pain in ACS presentation...
  71. doi request reprint Bupropion for smoking cessation in patients hospitalized with acute myocardial infarction: a randomized, placebo-controlled trial
    Mark J Eisenberg
    Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital McGill University, Montreal, Quebec City, Canada
    J Am Coll Cardiol 61:524-32. 2013
    ..The purpose of this study was to examine smoking cessation rates among smokers with AMI to determine whether bupropion, started in-hospital, is safe and can improve cessation rates at 1 year...
  72. doi request reprint Longitudinal evolution of risk of coronary heart disease in systemic lupus erythematosus
    Igor Karp
    Department of Social and Preventive Medicine, University of Montreal, Montreal, Quebec, Canada
    J Rheumatol 39:968-73. 2012
    ..To produce evidence on the longitudinal evolution of risk factors for coronary heart disease (CHD) in patients with systemic lupus erythematosus (SLE)...
  73. doi request reprint Outcomes for women and men who attend a heart failure clinic: results of a 12-month longitudinal study
    Debbie Ehrmann Feldman
    School of Rehabilitation, Faculty of Medicine, University of Montreal, Montreal, Canada
    J Card Fail 17:540-6. 2011
    ..Our aim was to describe 1-year outcomes in men and women attending specialized HF clinics...
  74. pmc Daily steps are low year-round and dip lower in fall/winter: findings from a longitudinal diabetes cohort
    Kaberi Dasgupta
    Department of Medicine, Division of Clinical Epidemiology, McGill University Health Centre, 687 Pine Avenue West, Montreal, Canada
    Cardiovasc Diabetol 9:81. 2010
    ..In this patient population, we conducted a longitudinal cohort study to objectively quantify seasonal variations both in walking and in two vascular risk factors associated with activity levels, hemoglobin A1C and blood pressure...
  75. pmc Quality of life after acute myocardial infarction: a comparison of diabetic versus non-diabetic acute myocardial infarction patients in Quebec acute care hospitals
    Ewurabena Simpson
    Division of Clinical Epidemiology, The Montreal General Hospital Research Institute, Montreal, Quebec, Canada
    Health Qual Life Outcomes 3:80. 2005
    ..Due to the rising incidence of these comorbid conditions, it is important to examine the synergistic impact of diabetes mellitus and AMI on QOL...
  76. ncbi request reprint Use of stress testing early after coronary artery bypass graft surgery
    Mark J Eisenberg
    Jewish General Hospital, Montreal, Quebec, Canada
    Am J Cardiol 97:810-6. 2006
    ....
  77. doi request reprint Changing mortality in congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, University of Montreal, Quebec, Canada
    J Am Coll Cardiol 56:1149-57. 2010
    ..This study sought to characterize temporal trends in all-cause mortality in patients with congenital heart disease (CHD)...
  78. ncbi request reprint Invasive versus noninvasive management of ST-elevation acute myocardial infarction: a review of clinical trials and observational studies
    Christine A Beck
    Division of Clinical Epidemiology, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Am Heart J 149:194-9. 2005
    ..Despite decades of research, it is still unclear whether patients with uncomplicated ST-segment elevation acute myocardial infarction (AMI) should be managed with an invasive or a noninvasive approach after successful thrombolysis...
  79. pmc Factors related to time to admission to specialized multidisciplinary clinics in patients with congestive heart failure
    Debbie Ehrmann Feldman
    University of Montreal, School of Rehabilitation, Montreal, Canada
    Can J Cardiol 25:e347-52. 2009
    ..Congestive heart failure (CHF) is a common cause of hospitalization and has a poor prognosis. Specialized multidisciplinary clinics are effective in the management of CHF...
  80. ncbi request reprint Impact of age on hospital course and cost of coronary artery bypass grafting
    Jung H Chee
    Division of Internal Medicine, McGill University Health Centre Royal Victoria Hospital, Montreal, Quebec, Canada
    Am J Cardiol 93:768-71. 2004
    ..Given the aging North American population, these results have important implications for health care planning for the next several decades...
  81. doi request reprint Behavioural interventions for smoking cessation: a meta-analysis of randomized controlled trials
    Salvatore Mottillo
    Division of Cardiology and Clinical Epidemiology, Jewish General Hospital McGill University, 3755 Cote Ste Catherine Road, Suite A 118, Montreal, Quebec, Canada
    Eur Heart J 30:718-30. 2009
    ....
  82. pmc Differences in outcomes of patients with congestive heart failure prescribed celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs: population based study
    Marie Hudson
    Division of Clinical Epidemiology, Research Institute of McGill University Health Center, 1650 Cedar Avenue, Montreal, QC, H3G 1A4 Canada
    BMJ 330:1370. 2005
    ....
  83. doi request reprint Isolated aerobic exercise and weight loss: a systematic review and meta-analysis of randomized controlled trials
    Adrian Thorogood
    Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital McGill University, Montreal, Quebec, Canada
    Am J Med 124:747-55. 2011
    ..We conducted a systematic review and meta-analysis to evaluate the efficacy of isolated aerobic exercise programs in overweight and obese populations...
  84. ncbi request reprint A cost analysis of nonelective coronary artery bypass graft surgery
    Philippe D Violette
    Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    J Card Surg 21:621-7. 2006
    ..The goal of this study was to examine why cost differences exist between patients undergoing nonelective and elective CABG...
  85. pmc Sex differences in step count-blood pressure association: a preliminary study in type 2 diabetes
    Priya Manjoo
    Department of Medicine, Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Canada
    PLoS ONE 5:e14086. 2010
    ..Such information would be useful for "dosing" daily steps in clinical practice. This study aimed to quantify decrements in blood pressure and glycated hemoglobin (A1C) per 1,000 daily step increments...
  86. doi request reprint Angina with "normal" coronary arteries: sex differences in outcomes
    Karin H Humphries
    Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada
    Am Heart J 155:375-81. 2008
    ..The sex specificity of this finding is unclear. We therefore undertook an evaluation of sex differences in rehospitalization for acute coronary syndrome (ACS) or chest pain in patients with "angiographically normal" coronaries...
  87. ncbi request reprint Effects of hospital volume on long-term outcomes after percutaneous transluminal coronary angioplasty after acute myocardial infarction
    Michel Doucet
    Division of Clinical Epidemiology, The Montreal General Hospital Research Institute, The McGill University Health Center, Montreal, Quebec, Canada
    Am Heart J 144:144-50. 2002
    ..Volume of procedures has been associated with short-term outcome after percutaneous transluminal coronary angioplasty. However, the effect of hospital procedural volume on long-term outcome after PTCA is unknown...
  88. ncbi request reprint Routine versus selective functional testing after percutaneous coronary intervention in patients with diabetes mellitus
    Mehrdad Saririan
    McGill University Health Center, Montreal, Quebec, Canada
    J Invasive Cardiol 17:25-9. 2005
    ..Procedural rates did not differ significantly between the two groups. These results suggest that routine post-PCI FT in patients with diabetes is of little clinical value...
  89. ncbi request reprint Updated risk factor values and the ability of the multivariable risk score to predict coronary heart disease
    Igor Karp
    Department of Epidemiology and Biostatistics, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 160:707-16. 2004
    ..The results suggest that coronary risk assessment can be improved by utilizing updated risk factors and that the optimal frequency of updating may vary across subpopulations...
  90. ncbi request reprint Association between naproxen use and protection against acute myocardial infarction
    Elham Rahme
    Division of Clinical Epidemiology, Montreal General Hospital, 1650 Cedar Ave, Room L10 408, Montreal, Quebec, Canada H3G 1A4
    Arch Intern Med 162:1111-5. 2002
    ..Nonsteroidal anti-inflammatory drugs vary in their antithrombotic properties, with naproxen having a particularly effective antithrombotic potential...
  91. ncbi request reprint Quality of life after acute myocardial infarction among patients treated at sites with and without on-site availability of angiography
    Louise Pilote
    McGill University Health Centre, Montreal, Quebec, Canada
    Arch Intern Med 162:553-9. 2002
    ..Although mortality rates do not differ, it is unknown if quality of life (QOL) and functional status differ...
  92. ncbi request reprint Pharmacological treatment of congestive heart failure in Canada: a description of care in five provinces
    Jafna L Cox
    Department of Medicine, Dalhousie University, Halifax, Canada
    Can J Cardiol 21:337-43. 2005
    ..There have been major advances in the treatment of this condition over the past two decades, yet little information is currently available regarding the current status of CHF management in Canada...
  93. ncbi request reprint Emergence of sex differences in prevalence of high systolic blood pressure: analysis of a longitudinal adolescent cohort
    Kaberi Dasgupta
    Departments of Medicine, McGill University, Montreal, Quebec, Canada
    Circulation 114:2663-70. 2006
    ..High systolic blood pressure (SBP) occurs more frequently both among men and boys than among women and girls. No longitudinal study has investigated whether the impact of SBP determinants differ according to sex in youth...
  94. pmc The effectiveness of beta-blockers in women with congestive heart failure
    Golyar Keyhan
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Center, 1650 Cedar Avenue, Rm L10 421, Montreal, Quebec, Canada, H3G 1A4
    J Gen Intern Med 22:955-61. 2007
    ..Beta-blockers have been shown to improve survival in patients with congestive heart failure (CHF). However, few studies have looked at the effects of these medications specifically in women...
  95. ncbi request reprint Amiodarone and the risk of bradyarrhythmia requiring permanent pacemaker in elderly patients with atrial fibrillation and prior myocardial infarction
    Vidal Essebag
    Department of Cardiology and Division of Clinical Epidemiology, McGill University Health Center, Montreal, Canada
    J Am Coll Cardiol 41:249-54. 2003
    ..The aim of this study was to determine whether the use of amiodarone in patients with atrial fibrillation (AF) increases the risk of bradyarrhythmia requiring a permanent pacemaker...
  96. doi request reprint Atrial arrhythmias in adults with congenital heart disease
    Judith Bouchardy
    McGill Adult Unit for Congenital Heart Disease Excellence, McGill University Health Center and the Jewish General Hospital, Montreal, Quebec, Canada
    Circulation 120:1679-86. 2009
    ..Adults with congenital heart lesions constitute a rapidly growing group of patients with cardiovascular disease. We hypothesized that atrial arrhythmias increase with age and impair health outcomes in this population...
  97. ncbi request reprint Medical therapy in patients undergoing percutaneous coronary intervention: results from the ROSETTA registry
    Mark J Eisenberg
    Jewish General Hospital McGill University, Montreal, Canada
    Can J Cardiol 19:1009-15. 2003
    ..However, little is known about medication use among patients with coronary artery disease who undergo percutaneous coronary intervention (PCI)...
  98. doi request reprint Planning the specialized care of adult congenital heart disease patients: from numbers to guidelines; an epidemiologic approach
    Ariane J Marelli
    McGill Adult Unit for Congenital Heart Disease Excellence MAUDE Unit, Montreal, Canada
    Am Heart J 157:1-8. 2009
    ..In conclusion, we demonstrate that 1 regional ACHD center for a population of 2.0 million adults appears to be closer to what is required for improving access to specialized care for patients with ACHD in the United States and Canada...
  99. doi request reprint Reducing the variance of the prescribing preference-based instrumental variable estimates of the treatment effect
    Michal Abrahamowicz
    Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 174:494-502. 2011
    ..Therefore, the new method improved the overall accuracy of IV estimates in studies with unobserved confounding and time-varying prescribing preferences...
  100. ncbi request reprint Congenital heart disease in the general population: changing prevalence and age distribution
    Ariane J Marelli
    McGill Adult Unit for Congenital Heart Disease, McGill University Health Center, 1650 Cedar Ave, Montreal, Quebec, Canada H3G 1A4
    Circulation 115:163-72. 2007
    ..We determined the prevalence, age distribution, and proportion of adults and children with severe and other forms of CHD in the general population from 1985 to 2000...
  101. doi request reprint Cardiovascular outcomes after a change in prescription policy for clopidogrel
    Cynthia A Jackevicius
    Western University of Health Sciences, College of Pharmacy, 309 E Second St, Pomona, CA 91766, USA
    N Engl J Med 359:1802-10. 2008
    ....