Affiliation: McGill University
- The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiationAnastasia Nijnik
Wellcome Trust Genome Campus, The Wellcome Trust Sanger Institute, Cambridge, United Kingdom
Blood 119:1370-9. 2012..Overall, these data establish a role for Mysm1 in the maintenance of BM stem cell function, in the control of oxidative stress and genetic stability in hematopoietic progenitors, and in the development of lymphoid and erythroid lineages...
- The role of sphingosine-1-phosphate transporter Spns2 in immune system functionAnastasia Nijnik
Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
J Immunol 189:102-11. 2012..Other components of the S1P signaling network are investigated as drug targets for immunosuppressive therapy, but the selective action of Spns2 may present an advantage in this regard...
- Immunomodulatory approaches for prevention and treatment of infectious diseasesAnastasia Nijnik
Department of Physiology and the Complex Traits Group, McGill University, Canada Electronic address
Curr Opin Microbiol 16:590-5. 2013..In this review we will cover prominent examples of immunomodulatory therapies already in clinical use, as well as the recent advances in the development of new immunomodulators in ongoing clinical trials. ..