Carol M Miyamoto

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi request reprint Involvement of LuxR, a quorum sensing regulator in Vibrio harveyi, in the promotion of metabolic genes: argA, purM, lysE and rluA
    Carol M Miyamoto
    Department of Biochemistry, Room 813, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada H3G 1Y6
    Biochim Biophys Acta 1759:296-307. 2006
  2. pmc Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR
    Gilles Brackman
    Laboratory of Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B 9000 Ghent, Belgium
    BMC Microbiol 8:149. 2008
  3. ncbi request reprint LuxO controls luxR expression in Vibrio harveyi: evidence for a common regulatory mechanism in Vibrio
    Carol M Miyamoto
    Department of Biochemistry, Room 813, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada, H3G 1Y6
    Mol Microbiol 48:537-48. 2003
  4. ncbi request reprint MetR and CRP bind to the Vibrio harveyi lux promoters and regulate luminescence
    Jaidip Chatterjee
    Department of Biochemistry, Room 813, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, H3G 1Y6, Canada
    Mol Microbiol 46:101-11. 2002
  5. ncbi request reprint LitR, a new transcriptional activator in Vibrio fischeri, regulates luminescence and symbiotic light organ colonization
    Pat M Fidopiastis
    Pacific Biomedical Research Center, University of Hawai i, Honolulu, 96813, USA
    Mol Microbiol 45:131-43. 2002
  6. ncbi request reprint The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding activity of the transcriptional regulator protein luxR
    Tom Defoirdt
    Laboratory of Microbial Ecology and Technology LabMET, Ghent University, Coupure Links 653, 9000 Ghent, Belgium
    Environ Microbiol 9:2486-95. 2007
  7. pmc Cloning and characterization of the bile salt hydrolase genes (bsh) from Bifidobacterium bifidum strains
    Geun Bae Kim
    Department of Food Science and Agricultural Chemistry, McGill University, 21111 Lakeshore Rd, Ste Anne de Bellevue, Quebec H9X 3V9, Canada
    Appl Environ Microbiol 70:5603-12. 2004

Collaborators

  • Paul V Dunlap
  • Edward Ruby
  • T Defoirdt
  • Edward A Meighen
  • Gilles Brackman
  • Geun Bae Kim
  • Pat M Fidopiastis
  • Jaidip Chatterjee
  • Serge Van Calenbergh
  • Tom Coenye
  • Peter Bossier
  • Hans Nelis
  • Byong H Lee
  • Nicolas Skouris
  • Athina Zouzoulas
  • Michael G Jobling
  • B Franz Lang

Detail Information

Publications7

  1. ncbi request reprint Involvement of LuxR, a quorum sensing regulator in Vibrio harveyi, in the promotion of metabolic genes: argA, purM, lysE and rluA
    Carol M Miyamoto
    Department of Biochemistry, Room 813, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada H3G 1Y6
    Biochim Biophys Acta 1759:296-307. 2006
    ..Based on analysis of luxR-dependent promoters, particularly that of argA, we describe a LuxR binding site, and implicate the coordination of LuxR with ArgR...
  2. pmc Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR
    Gilles Brackman
    Laboratory of Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B 9000 Ghent, Belgium
    BMC Microbiol 8:149. 2008
    ..The compounds were also evaluated in an in vivo assay measuring the reduction of Vibrio harveyi virulence towards Artemia shrimp...
  3. ncbi request reprint LuxO controls luxR expression in Vibrio harveyi: evidence for a common regulatory mechanism in Vibrio
    Carol M Miyamoto
    Department of Biochemistry, Room 813, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada, H3G 1Y6
    Mol Microbiol 48:537-48. 2003
    ..harveyi and V. fischeri and recently in Vibrio cholerae suggest that the luxO-luxRvh couple is a central feature of this quorum-sensing system in members of the genus Vibrio...
  4. ncbi request reprint MetR and CRP bind to the Vibrio harveyi lux promoters and regulate luminescence
    Jaidip Chatterjee
    Department of Biochemistry, Room 813, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, H3G 1Y6, Canada
    Mol Microbiol 46:101-11. 2002
    ....
  5. ncbi request reprint LitR, a new transcriptional activator in Vibrio fischeri, regulates luminescence and symbiotic light organ colonization
    Pat M Fidopiastis
    Pacific Biomedical Research Center, University of Hawai i, Honolulu, 96813, USA
    Mol Microbiol 45:131-43. 2002
    ..Thus, the litR mutation appears to represent a novel class of mutations in which the loss of a regulatory gene function enhances the bacterium's competence in initiating a benign infection...
  6. ncbi request reprint The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding activity of the transcriptional regulator protein luxR
    Tom Defoirdt
    Laboratory of Microbial Ecology and Technology LabMET, Ghent University, Coupure Links 653, 9000 Ghent, Belgium
    Environ Microbiol 9:2486-95. 2007
    ..Therefore, our data indicate that the furanone blocks quorum sensing in V. harveyi by rendering the quorum sensing master regulator protein LuxR(Vh) unable to bind to the promoter sequences of quorum sensing-regulated genes...
  7. pmc Cloning and characterization of the bile salt hydrolase genes (bsh) from Bifidobacterium bifidum strains
    Geun Bae Kim
    Department of Food Science and Agricultural Chemistry, McGill University, 21111 Lakeshore Rd, Ste Anne de Bellevue, Quebec H9X 3V9, Canada
    Appl Environ Microbiol 70:5603-12. 2004
    ..PCR amplification with the type-specific primer set revealed the high level of sequence homology in their bsh genes within the species of B. bifidum...