D Menzies

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients
    Shama D Ahuja
    Bureau of Tuberculosis, New York, New York, United States of America
    PLoS Med 9:e1001300. 2012
  2. pmc How methodologic differences affect results of economic analyses: a systematic review of interferon gamma release assays for the diagnosis of LTBI
    Olivia Oxlade
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 8:e56044. 2013
  3. pmc Treatment of drug-resistant tuberculosis
    Lancelot Pinto
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, QC, Canada
    Infect Drug Resist 4:129-35. 2011
  4. pmc Reduced transmissibility of East African Indian strains of Mycobacterium tuberculosis
    Amr S Albanna
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    PLoS ONE 6:e25075. 2011
  5. ncbi request reprint Can social interventions prevent tuberculosis?: the Papworth experiment (1918-1943) revisited
    Anurag Bhargava
    Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada
    Am J Respir Crit Care Med 186:442-9. 2012
  6. pmc Tuberculosis and homelessness in Montreal: a retrospective cohort study
    Jason Tan de Bibiana
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    BMC Public Health 11:833. 2011
  7. pmc Cost-effectiveness of novel vaccines for tuberculosis control: a decision analysis study
    Chia Lin Tseng
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Canada
    BMC Public Health 11:55. 2011
  8. pmc Direct and indirect costs of tuberculosis among immigrant patients in the Netherlands
    Sandra V Kik
    Research Unit, KNCV Tuberculosis Foundation, The Hague, The Netherlands
    BMC Public Health 9:283. 2009
  9. pmc Tuberculosis screening of travelers to higher-incidence countries: a cost-effectiveness analysis
    Michael Tan
    Respiratory Epidemiology Unit, Montreal Chest Institute, 3650 St, Urbain St, Montreal, Quebec, H2X 2P4, Canada
    BMC Public Health 8:201. 2008
  10. pmc Impact of DOTS expansion on tuberculosis related outcomes and costs in Haiti
    Vary Jacquet
    National Tuberculosis Control Programme, Port au Prince, Haiti
    BMC Public Health 6:209. 2006

Detail Information

Publications112 found, 100 shown here

  1. pmc Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients
    Shama D Ahuja
    Bureau of Tuberculosis, New York, New York, United States of America
    PLoS Med 9:e1001300. 2012
    ..We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB...
  2. pmc How methodologic differences affect results of economic analyses: a systematic review of interferon gamma release assays for the diagnosis of LTBI
    Olivia Oxlade
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 8:e56044. 2013
    ....
  3. pmc Treatment of drug-resistant tuberculosis
    Lancelot Pinto
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, QC, Canada
    Infect Drug Resist 4:129-35. 2011
    ..What is the best approach to the treatment of drug-resistant tuberculosis (TB)?..
  4. pmc Reduced transmissibility of East African Indian strains of Mycobacterium tuberculosis
    Amr S Albanna
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    PLoS ONE 6:e25075. 2011
    ..Some reports have associated certain lineages with particular clinical phenotypes, but there is still insufficient information regarding the clinical and epidemiologic implications of MTB lineage variation...
  5. ncbi request reprint Can social interventions prevent tuberculosis?: the Papworth experiment (1918-1943) revisited
    Anurag Bhargava
    Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada
    Am J Respir Crit Care Med 186:442-9. 2012
    ..There is consensus on the need to address social determinants of tuberculosis (TB) to achieve TB control, but evidence based on interventions is lacking...
  6. pmc Tuberculosis and homelessness in Montreal: a retrospective cohort study
    Jason Tan de Bibiana
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    BMC Public Health 11:833. 2011
    ..9/100,000. The objectives of this study were to describe the epidemiology of TB among homeless persons in Montreal and assess patterns of transmission and sharing of key locations...
  7. pmc Cost-effectiveness of novel vaccines for tuberculosis control: a decision analysis study
    Chia Lin Tseng
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Canada
    BMC Public Health 11:55. 2011
    ....
  8. pmc Direct and indirect costs of tuberculosis among immigrant patients in the Netherlands
    Sandra V Kik
    Research Unit, KNCV Tuberculosis Foundation, The Hague, The Netherlands
    BMC Public Health 9:283. 2009
    ..Little empirical information is available about direct and indirect TB-related costs that patients face in these high-income countries. We assessed the direct and indirect costs of immigrants with TB in the Netherlands...
  9. pmc Tuberculosis screening of travelers to higher-incidence countries: a cost-effectiveness analysis
    Michael Tan
    Respiratory Epidemiology Unit, Montreal Chest Institute, 3650 St, Urbain St, Montreal, Quebec, H2X 2P4, Canada
    BMC Public Health 8:201. 2008
    ..We sought to compare four screening interventions for travelers from low-incidence countries, who visit countries with varying tuberculosis incidence...
  10. pmc Impact of DOTS expansion on tuberculosis related outcomes and costs in Haiti
    Vary Jacquet
    National Tuberculosis Control Programme, Port au Prince, Haiti
    BMC Public Health 6:209. 2006
    ..We estimated potential costs and benefits of DOTS expansion in Haiti from the government, and societal perspectives...
  11. pmc Screening immigrants to Canada for tuberculosis: chest radiography or tuberculin skin testing?
    Dick Menzies
    Repiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, QC
    CMAJ 169:1035-6. 2003
  12. ncbi request reprint In closely monitored patients, adherence in the first month predicts completion of therapy for latent tuberculosis infection
    D Menzies
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 9:1343-8. 2005
    ..Current therapy for latent TB infection (LTBI) is long, and requires close follow-up. This results in sub-optimal adherence-the major reason for failure of therapy...
  13. ncbi request reprint Meta-analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research
    Dick Menzies
    McGill University, Montreal, Quebec, Canada
    Ann Intern Med 146:340-54. 2007
    ..Until recently, the tuberculin skin test was the only test for detecting latent tuberculosis (TB) infection, but 2 ex vivo interferon-gamma release assays (IGRAs) are now commercially licensed...
  14. ncbi request reprint Risk of tuberculosis infection and disease associated with work in health care settings
    D Menzies
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Canada
    Int J Tuberc Lung Dis 11:593-605. 2007
    ..Tuberculosis (TB) in health care workers (HCWs) was not considered a serious problem following the advent of effective antibiotic therapy. Interest was re-stimulated by the occurrence of several major nosocomial outbreaks...
  15. ncbi request reprint Thinking in three dimensions: a web-based algorithm to aid the interpretation of tuberculin skin test results
    D Menzies
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Canada
    Int J Tuberc Lung Dis 12:498-505. 2008
    ..Accurate interpretation of TST requires consideration of three dimensions-the size of the skin reaction, the positive predictive value (PPV) and risk of disease...
  16. ncbi request reprint Effect of ultraviolet germicidal lights installed in office ventilation systems on workers' health and wellbeing: double-blind multiple crossover trial
    Dick Menzies
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Quebec, Canada
    Lancet 362:1785-91. 2003
    ..We assessed whether ultraviolet germicidal irradiation (UVGI) of drip pans and cooling coils within ventilation systems of office buildings would reduce microbial contamination, and thus occupants' work-related symptoms...
  17. ncbi request reprint Costs for tuberculosis care in Canada
    Dick Menzies
    Montreal Chest Institute, 3650 St Urbain, Rm K1 24, Montreal, QC
    Can J Public Health 99:391-6. 2008
    ..We have estimated tuberculosis (TB)-related expenditures by governments and other third parties in Canada in 2004, in order to compare spending on different activities, by various jurisdictions, and in different regions...
  18. doi request reprint Systematic reviews and meta-analyses
    D Menzies
    Respiratory Epidemiology Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 15:582-93. 2011
    ..These reviews can help identify research priorities as areas where knowledge is uncertain, and also those topics where little additional work is required...
  19. ncbi request reprint Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis infection: a randomized trial
    Dick Menzies
    Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Ann Intern Med 149:689-97. 2008
    ..Treatment of latent tuberculosis infection with isoniazid for 9 months is complicated by poor patient adherence and the need for close follow-up of side effects, especially hepatotoxicity. Shorter and safer regimens are needed...
  20. pmc Effect of duration and intermittency of rifampin on tuberculosis treatment outcomes: a systematic review and meta-analysis
    Dick Menzies
    Respiratory and Epidemiology Clinical Research Unit, Montreal Chest Institute and Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada
    PLoS Med 6:e1000146. 2009
    ..We conducted a systematic review of treatment regimens for active TB, to assess the effect of duration and intermittency of rifampin use on TB treatment outcomes...
  21. ncbi request reprint Factors associated with tuberculin conversion in Canadian microbiology and pathology workers
    Dick Menzies
    Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Respir Crit Care Med 167:599-602. 2003
    ....
  22. pmc Recent developments in treatment of latent tuberculosis infection
    Dick Menzies
    Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Indian J Med Res 133:257-66. 2011
    ..Hence, LTBI therapy should be given only to those with positive tests for LTBI. We conclude that LTBI therapy is considerably underutilized in many settings, particularly in low and middle income countries...
  23. ncbi request reprint Treatment completion and costs of a randomized trial of rifampin for 4 months versus isoniazid for 9 months
    Dick Menzies
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, 3650 St Urbain, Room K1 24, Montreal, PQ, H2X 2P4 Canada
    Am J Respir Crit Care Med 170:445-9. 2004
    ..In conclusion, completion of therapy was significantly better with 4 months of rifampin and major side effects were somewhat lower. Further studies are needed to assess the safety and efficacy of the 4-month rifampin regimen...
  24. doi request reprint Predicting outcomes and drug resistance with standardised treatment of active tuberculosis
    O Oxlade
    McGill University, Respiratory Epidemiology Unit, Montreal Chest Institute, 3650 St Urbain, Room K1 24, Montreal, QC, H2X 2P4, Canada
    Eur Respir J 36:870-7. 2010
    ..We predict substantial public health benefits from changing from the 8-month to the 6-month regimen. However in almost all settings the current standardised retreatment regimen will no longer be adequate...
  25. ncbi request reprint Interferon-gamma release assays and TB screening in high-income countries: a cost-effectiveness analysis
    O Oxlade
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Canada
    Int J Tuberc Lung Dis 11:16-26. 2007
    ..We compared the cost-effectiveness of TST and IGRA in different populations and clinical situations, and with variation of a number of parameters...
  26. ncbi request reprint The use of environmental factors as adjuncts to traditional tuberculosis contact investigation
    C Muecke
    Department of Public Health, McGill University Health Centre, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 10:530-5. 2006
    ..A 25-year-old university student was diagnosed with cavitary pulmonary and laryngeal tuberculosis following symptoms of underlying cough of 6 months' duration...
  27. ncbi request reprint Yield of tuberculin screening among injection drug users
    P Brassard
    Division of Clinical Epidemiology, Royal Victoria Hospital, Ross Pavillion, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 8:988-93. 2004
    ..We quantified the prevalence and predictors of LTBI and level of adherence to medical evaluation in a population of IDUs in Montreal...
  28. doi request reprint Mycobacterium tuberculosis transmission over an 11-year period in a low-incidence, urban setting
    C Rossi
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 16:312-8. 2012
    ..Montreal, Canada, has a mean annual tuberculosis (TB) incidence of 9 per 100,000 population, 1996-2007...
  29. ncbi request reprint Global tuberculosis trends: a reflection of changes in tuberculosis control or in population health?
    O Oxlade
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 13:1238-46. 2009
    ..We have analyzed the association between changes in population health and health service indicators, and concomitant changes in TB incidence between 1990 and 2005...
  30. doi request reprint Clinical outcomes of pyrazinamide-monoresistant Mycobacterium tuberculosis in Quebec
    D P Yee
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Center, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 16:604-9. 2012
    ..In Quebec, 6.2% of all tuberculosis (TB) isolates from Canadian-born patients are resistant to pyrazinamide (PZA) alone. The clinical significance of PZA-monoresistant (PZA(MR)) TB is unknown...
  31. doi request reprint Potential cost-effectiveness of rifampin vs. isoniazid for latent tuberculosis: implications for future clinical trials
    K Esfahani
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 15:1340-6. 2011
    ..Standard treatment for latent tuberculosis infection (LTBI) is 9 months daily isoniazid (9INH). An alternative is 4 months daily rifampin (4RMP), associated with better completion and less toxicity; however, its efficacy remains uncertain...
  32. doi request reprint Microcolony culture techniques for tuberculosis diagnosis: a systematic review
    E Leung
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 16:16-23, i-iii. 2012
    ..The microscopic observation drug susceptibility (MODS) assay and the thin-layer agar (TLA) assay are inexpensive, rapid microcolony-based culture methods...
  33. ncbi request reprint Use of geographic and genotyping tools to characterise tuberculosis transmission in Montreal
    I Haase
    Department of Geography, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 11:632-8. 2007
    ..In Canada, tuberculosis (TB) is increasingly an urban health problem. Montreal is Canada's second-largest city and the second most frequent destination for new immigrants and refugees...
  34. ncbi request reprint Cost-effectiveness of tuberculosis control strategies among immigrants and refugees
    K Dasgupta
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, QC, H2X 2P4, Canada
    Eur Respir J 25:1107-16. 2005
    ..More effective alternatives include contact tracing delivered through primary care and increased investment in global tuberculosis control...
  35. doi request reprint The impact and cost-effectiveness of strategies to detect drug-resistant tuberculosis
    O Oxlade
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, QC, Canada
    Eur Respir J 39:626-34. 2012
    ..Our findings support the roll-out of rapid drug susceptibility testing at the moment of diagnosis to detect any form of INH and RIF resistance in all countries with moderate or greater burdens of drug-resistant TB...
  36. ncbi request reprint Tuberculosis surveillance among new immigrants in Montreal
    B Richards
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 9:858-64. 2005
    ..Foreign-born persons account for over 60% of Canadian tuberculosis (TB) incidence; immigrants with TB-related lung scarring ('inactive TB') are at particularly high risk, and represent an important target for preventive efforts...
  37. ncbi request reprint Hospital ventilation and risk for tuberculous infection in canadian health care workers. Canadian Collaborative Group in Nosocomial Transmission of TB
    D Menzies
    Montreal Chest Institute, 3650 St Urbain Street, Montreal, Quebec H2X 2P4, Canada
    Ann Intern Med 133:779-89. 2000
    ..The risk for and determinants of transmission of tuberculosis in hospitals caring for moderate numbers of patients with tuberculosis remain uncertain...
  38. ncbi request reprint Yield of casual contact investigation by the hour
    C Greenaway
    Jewish General Hospital, Montreal, Canada
    Int J Tuberc Lung Dis 7:S479-85. 2003
    ....
  39. pmc Germicidal ultraviolet irradiation in air conditioning systems: effect on office worker health and wellbeing: a pilot study
    D Menzies
    Department of Medicine and Epidemiology and Biostatistics, McGill University, Montreal, Canada
    Occup Environ Med 56:397-402. 1999
    ....
  40. ncbi request reprint Tuberculosis screening of immigrants to low-prevalence countries. A cost-effectiveness analysis
    K Schwartzman
    Respiratory Division, McGill University Health Centre, and Respiratory Epidemiology Unit, McGill University, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 161:780-9. 2000
    ..The cost-effectiveness of either strategy would be greatly enhanced by increased adherence to chemoprophylaxis recommendations. Radiographic screening of groups with a high prevalence of tuberculous infection will then likely save money...
  41. pmc Widespread pyrazinamide-resistant Mycobacterium tuberculosis family in a low-incidence setting
    Dao Nguyen
    Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada
    J Clin Microbiol 41:2878-83. 2003
    ..We conclude that a clonally related family of PZA-monoresistant M. tuberculosis isolates in Quebec represents historic rather than recent transmission...
  42. ncbi request reprint Patient and family costs associated with tuberculosis, including multidrug-resistant tuberculosis, in Ecuador
    V A Rouzier
    Department of Pediatrics, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 14:1316-22. 2010
    ..There is little published information on the costs of multidrug-resistant tuberculosis (MDR-TB) for patients and their families in low- or middle-income countries...
  43. ncbi request reprint False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria?
    M Farhat
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 10:1192-204. 2006
    ..However, TST specificity is reduced by bacille Calmette-Guérin (BCG) vaccination and exposure to non-tuberculous mycobacteria (NTM)...
  44. ncbi request reprint Feasibility and reliability of health-related quality of life measurements among tuberculosis patients
    M J Dion
    Respiratory Epidemiology Unit, McGill University, Montreal, Quebec, Canada
    Qual Life Res 13:653-65. 2004
    ..Intraclass correlation coefficients were 0.66 for the SF-36 physical component summary, 0.79 for the mental component summary, and 0.73 for the EQ-5D. These instruments appeared reliable in a highly selected group of TB patients...
  45. ncbi request reprint Delay in diagnosis among hospitalized patients with active tuberculosis--predictors and outcomes
    Christina Greenaway
    McGill University, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 165:927-33. 2002
    ..Institutional risk of TB transmission was poorly correlated with number of patients with TB and better correlated with indicators of patient care such as delayed diagnosis and treatment and overall TB-related patient mortality...
  46. doi request reprint Incidence of ethambutol-related visual impairment during treatment of active tuberculosis
    N Ezer
    Respiratory and Epidemiology Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Canada
    Int J Tuberc Lung Dis 17:447-55. 2013
    ..This could expose patients to the risk of blindness...
  47. ncbi request reprint Humoral response to Mycobacterium tuberculosis antigens in patients with tuberculosis in the Gambia
    C Greenaway
    Division of Infectious Diseases and Medical Microbiology, SMBD Jewish General Hospital, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 9:1112-9. 2005
    ..To determine and compare the sensitivity and specificity of four common mycobacterial antigens with three RD-1 region antigens in the serological diagnosis of active pulmonary tuberculosis (PTB) in the Gambia...
  48. pmc T-cell assay conversions and reversions among household contacts of tuberculosis patients in rural India
    M Pai
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 13:84-92. 2009
    ..In a pilot study, we determined conversions and reversions using QuantiFERON-TB Gold In-Tube((R)) (QFT) among household contacts of TB cases, and evaluated the effect of using various definitions and criteria for conversions...
  49. ncbi request reprint Efficacy of environmental measures in reducing potentially infectious bioaerosols during sputum induction
    Dick Menzies
    Montreal Chest Institute, Montreal, Quebec, Canada
    Infect Control Hosp Epidemiol 24:483-9. 2003
    ..To evaluate the airborne viable bacterial concentrations generated during sputum induction and their reduction with exhaust ventilation, ultraviolet germicidal irradiation (UVGI), or both...
  50. ncbi request reprint Chest radiograph abnormalities associated with tuberculosis: reproducibility and yield of active cases
    S Graham
    Internal Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Int J Tuberc Lung Dis 6:137-42. 2002
    ..Tertiary care referral centre specialising in respiratory diseases...
  51. doi request reprint Global survey of national tuberculosis drug policies
    A Paydar
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 15:613-9. 2011
    ..National tuberculosis (TB) programmes (NTPs) in 100 countries...
  52. doi request reprint Treatment of active tuberculosis in HIV-coinfected patients: a systematic review and meta-analysis
    Faiz A Khan
    Montreal Chest Institute, McGill University Health Centre, Montreal, Canada
    Clin Infect Dis 50:1288-99. 2010
    ..Patients with human immunodeficiency virus (HIV) infection and tuberculosis have an increased risk of death, treatment failure, and relapse...
  53. ncbi request reprint Diversity of Mycobacterium tuberculosis isolates in an immigrant population: evidence against a founder effect
    Sophie Kulaga
    Joint Department of Epidemiology and Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 159:507-13. 2004
    ..A mycobacterial "founder effect" is unlikely to account for the high proportion of shared isolates among Haitian-born Montrealers. Recent transmission remains the most likely explanation...
  54. doi request reprint Impact of treatment completion, intolerance and adverse events on health system costs in a randomised trial of 4 months rifampin or 9 months isoniazid for latent TB
    Anne Aspler
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Canada
    Thorax 65:582-7. 2010
    ....
  55. ncbi request reprint Domestic returns from investment in the control of tuberculosis in other countries
    Kevin Schwartzman
    Respiratory Epidemiology Unit, Montreal Chest Institute, McGill University, Montreal, QC, Canada
    N Engl J Med 353:1008-20. 2005
    ..We hypothesized that investments to improve the control of tuberculosis in selected high-incidence countries would prove to be cost saving for the United States by reducing the incidence of the disease among migrants...
  56. ncbi request reprint Yield of smear, culture and amplification tests from repeated sputum induction for the diagnosis of pulmonary tuberculosis
    K Al Zahrani
    Montreal Chest Institute, McGill University, PQ, Canada
    Int J Tuberc Lung Dis 5:855-60. 2001
    ..Yield of PCR also increased with the greater number of induced samples tested. CONCLUSIONS: Repeated sputum induction could considerably improve diagnostic accuracy for pulmonary TB...
  57. ncbi request reprint Agreement in measuring socio-economic status: area-based versus individual measures
    K Demissie
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Chronic Dis Can 21:1-7. 2000
    ..Caution should therefore be used in designing or interpreting the results of studies in which area-based SES measures are used to test hypotheses or control for confounding...
  58. pmc Is there a role for mask continuous positive airway pressure in acute respiratory failure due to COPD? Lessons from a retrospective audit of 3 different cohorts
    Sandra Dial
    Respiratory Epidemiology Unit, Montreal Chest Institute, McGill University, Montreal, QC, Canada
    Int J Chron Obstruct Pulmon Dis 1:65-72. 2006
    ....
  59. ncbi request reprint How close is close enough? Exploring matching criteria in the estimation of recent transmission of tuberculosis
    Andrea Benedetti
    Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 172:318-26. 2010
    ....
  60. pmc Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update
    Madhukar Pai
    McGill University and Montreal Chest Institute, Montreal, Quebec, Canada
    Ann Intern Med 149:177-84. 2008
    ..A recent meta-analysis showed that IGRAs have high specificity, even among populations that have received bacille Calmette-Guérin (BCG) vaccination. Sensitivity was suboptimal for TST and IGRAs...
  61. pmc Major Mycobacterium tuberculosis lineages associate with patient country of origin
    Michael B Reed
    Department of Medicine, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    J Clin Microbiol 47:1119-28. 2009
    ..We believe that this independent validation of the LSP method should encourage researchers to adopt this system in investigations aimed at elucidating the role of strain variation in TB...
  62. ncbi request reprint Incidence of serious side effects from first-line antituberculosis drugs among patients treated for active tuberculosis
    Daphne Yee
    Respiratory Epidemiology Unit, Montreal Chest Institute, 1110 Pine Avenue West, Room 103, Montreal, PQ, H3A 1A3 Canada
    Am J Respir Crit Care Med 167:1472-7. 2003
    ..0; 95% CI, 1.5 to 43). The incidence of pyrazinamide-induced hepatotoxicity and rash during treatment for active TB was substantially higher than with the other first-line anti-TB drugs, and higher than previously recognized...
  63. doi request reprint Challenges to tuberculin screening and follow-up in an urban Aboriginal sample in Montreal, Canada
    Paul Brassard
    Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre, and Royal Victoria Hospital, Montreal, Canada
    J Health Care Poor Underserved 19:369-79. 2008
    ..Tuberculin screening in this population can be an effective strategy for identifying TST reactive individuals; however, screening efforts will have minimal impact without additional efforts in this high-risk group...
  64. ncbi request reprint Dwellings, crowding, and tuberculosis in Montreal
    Ian Wanyeki
    Respiratory Epidemiology Unit, McGill University, Canada
    Soc Sci Med 63:501-11. 2006
    ....
  65. doi request reprint Knowledge and perceptions of tuberculosis among a sample of urban Aboriginal people
    Paul Brassard
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Avenue West, Ross Pavilion, R4 29, Montreal, PQ, Canada H3A 1A1
    J Community Health 33:192-8. 2008
    ..We conclude that there is a lack of knowledge and several misconceptions about TB among our sample of urban Aboriginal peoples...
  66. pmc Fading of auramine-stained mycobacterial smears and implications for external quality assurance
    Jessica Minion
    Department of Epidemiology, McGill University, Montreal, Canada
    J Clin Microbiol 49:2024-6. 2011
    ..We stored auramine-stained slides and reexamined them over time. Slides stored in all environments faded quickly, with significant changes in the proportion of positive slides in as little as 1 week...
  67. pmc Serial testing of health care workers for tuberculosis using interferon-gamma assay
    Madhukar Pai
    Division of Epidemiology, School of Public Health, University of California, Berkeley, CA, USA
    Am J Respir Crit Care Med 174:349-55. 2006
    ..Although interferon-gamma (IFN-gamma) assays are promising alternatives to the tuberculin skin test (TST), their serial testing performance is unknown...
  68. ncbi request reprint Invasive aspergillosis in patients with chronic obstructive pulmonary diseases
    Aziz Muquim
    Respiratory Epidemiology and Clinical Research Unit of the Montreal Chest Institute, Montreal, Qubec, Canada
    Can Respir J 12:199-204. 2005
    ..To determine the outcomes, and clinical and therapeutic factors associated with the development of invasive pulmonary aspergillosis (IPA) in patients with obstructive pulmonary diseases...
  69. pmc Nosocomial tuberculosis in India
    Madhukar Pai
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada
    Emerg Infect Dis 12:1311-8. 2006
    ..Finally, we outline the critical information needed to effectively address the problem of nosocomial transmission of TB in India...
  70. ncbi request reprint Autotransfusion of shed mediastinal blood: a risk factor for mediastinitis after cardiac surgery? Results of a cluster investigation
    Sandra Dial
    Department of Critical Care, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, PQ, Canada
    Chest 124:1847-51. 2003
    ..After the introduction of autotransfusion of shed mediastinal blood following cardiac surgery, the incidence of mediastinitis increased. The role of autotransfusion in the increased occurrence of this serious complication was examined...
  71. ncbi request reprint Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass
    Sandra Dial
    Department of Critical Care, SMBD Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    J Thorac Cardiovasc Surg 130:654-61. 2005
    ....
  72. pmc Sensitivities and specificities of spoligotyping and mycobacterial interspersed repetitive unit-variable-number tandem repeat typing methods for studying molecular epidemiology of tuberculosis
    Allison N Scott
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    J Clin Microbiol 43:89-94. 2005
    ....
  73. pmc Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies
    Sandra Dial
    Department of Critical Care, Montreal Chest Institute, QC
    CMAJ 171:33-8. 2004
    ..Reduced gastric acidity has been suggested as a risk factor, and we hypothesized that proton pump inhibitors, because of their potency, may be an independent risk factor for this problem...
  74. ncbi request reprint Validation of ICD-9 diagnostic codes for bronchopulmonary dysplasia in Quebec's provincial health care databases
    J S Landry
    Respiratory Epidemiology and Clinical Research Unit, McGill University, Montreal, Quebec, Canada
    Chronic Dis Inj Can 33:47-52. 2012
    ..The aim of this study was to validate the use of ICD-9 diagnostic codes for BPD in administrative databases to allow for their use in health care utilization analyses...
  75. doi request reprint Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis
    J Minion
    Dept of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada
    Eur Respir J 38:1398-405. 2011
    ..Further studies are needed to evaluate the potential value of the LAM assay in individuals with advanced HIV or for diagnosis of paediatric TB...
  76. ncbi request reprint What does tuberculin reactivity after bacille Calmette-Guérin vaccination tell us?
    D Menzies
    Department of Medicine, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Clin Infect Dis 31:S71-4. 2000
    ..Therefore, the ideal BCG vaccine would produce a scar at the site of injection to identify individuals who have been vaccinated but would have no effect on tuberculin reactivity...
  77. ncbi request reprint Contact investigation of a case of pulmonary and laryngeal tuberculosis
    C Muecke
    Infectious Diseases Control Unit of the Direction de la santé publique, Montreal Chest Institute, Montreal, Canada
    Can Commun Dis Rep 29:91-2. 2003
  78. ncbi request reprint Initial drug resistance and tuberculosis treatment outcomes: systematic review and meta-analysis
    Woojin Lew
    Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Ann Intern Med 149:123-34. 2008
    ..Despite the increasing prevalence of drug-resistant tuberculosis, most low- and middle-income countries use standardized regimens, without assessment of drug susceptibility...
  79. ncbi request reprint Measurement of health preferences among patients with tuberculous infection and disease
    Marie Josée Dion
    Respiratory Epidemiology Unit, McGill University, Montreal, Quebec, Canada
    Med Decis Making 22:S102-14. 2002
    ..Administration of the visual analogue scale and standard gamble instruments appeared reliable in a selected group of tuberculosis patients. Major barriers to recruitment were language and mobility in this largely foreign-born population...
  80. ncbi request reprint Risk of lung cancer following nonmalignant respiratory conditions: evidence from two case-control studies in Montreal, Canada
    Agnihotram V Ramanakumar
    Centre de Recherche du CHUM, Universite de Montreal, Montreal, Que, Canada
    Lung Cancer 53:5-12. 2006
    ..6-2.4. Our results support the hypothesis that some nonmalignant respiratory diseases may be independent risk factors for lung cancer...
  81. doi request reprint Influence of multidrug resistance on tuberculosis treatment outcomes with standardized regimens
    Anton Mak
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Canada
    Am J Respir Crit Care Med 178:306-12. 2008
    ..Multidrug-resistant tuberculosis (TB) poses a major challenge to global TB control. We analyzed the association between estimated prevalence of initial or acquired MDR-TB, and treatment outcomes reported nationally...
  82. ncbi request reprint Factors associated with humoral response to ESAT-6, 38 kDa and 14 kDa in patients with a spectrum of tuberculosis
    V M C Silva
    Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 7:478-84. 2003
    ..Tertiary care chest hospital in Montreal, Canada, where the average annual incidence of TB is 10/100,000 population...
  83. ncbi request reprint Cost of tuberculosis diagnosis and treatment from the patient perspective in Lusaka, Zambia
    A Aspler
    Respiratory Epidemiology Unit, Montreal Chest Institute, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 12:928-35. 2008
    ..Urban primary health centres in Lusaka, Zambia...
  84. ncbi request reprint Preventive chemotherapy. Where has it got us? Where to go next?
    J Landry
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Int J Tuberc Lung Dis 12:1352-64. 2008
    ..If these can be overcome, preventive treatment holds the promise to substantially assist in the achievement of global control of TB...
  85. pmc Genomic characterization of an endemic Mycobacterium tuberculosis strain: evolutionary and epidemiologic implications
    Dao Nguyen
    Division of Infectious Diseases and Medical Microbiology, McGil University Health Centre, Montreal, Quebec, Canada
    J Clin Microbiol 42:2573-80. 2004
    ..These results provide insight into the evolution of genotypes in endemic strains and the potential for false clustering in molecular epidemiologic studies...
  86. doi request reprint Occupation-related respiratory infections revisited
    Daphne Ling
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, QC H2X 2P4, Canada
    Infect Dis Clin North Am 24:655-80. 2010
    ..This review focuses on TB, influenza, and SARS, because the published literature is extensive for these 3 infections. The lessons from these 3 are relevant for all nosocomial pulmonary infectious diseases...
  87. ncbi request reprint Adverse reactions to first-line antituberculosis drugs
    Eric J Forget
    Respiratory Epidemiology Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, H2X 2P4, Canada
    Expert Opin Drug Saf 5:231-49. 2006
    ..Tuberculosis continues to be a major cause of morbidity and mortality worldwide. Currently available drugs are effective for treatment of the disease or latent infection, but may cause serious adverse effects...
  88. ncbi request reprint The long-term health and economic benefits of DOTS implementation in Ecuador
    Olivia Oxlade
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, QC, Canada
    Can J Public Health 97:14-9. 2006
    ....
  89. doi request reprint Microscopic-observation drug susceptibility and thin layer agar assays for the detection of drug resistant tuberculosis: a systematic review and meta-analysis
    Jessica Minion
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada
    Lancet Infect Dis 10:688-98. 2010
    ..We did a systematic review and meta-analysis to investigate the accuracy of microscopic-observation drug susceptibility (MODS) and thin layer agar (TLA) assays for rapid screening of patients at risk of drug-resistant tuberculosis...
  90. ncbi request reprint A cohort study showed that health insurance databases were accurate to distinguish chronic obstructive pulmonary disease from asthma and classify disease severity
    Jason McKnight
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, 3650 St Urbain Street, Montreal, Quebec, H2X 2P4, Canada
    J Clin Epidemiol 58:206-8. 2005
  91. ncbi request reprint Re-evaluation of acid-base prediction rules in patients with chronic respiratory acidosis
    Tereza Martinu
    Respiratory Epidemiology Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
    Can Respir J 10:311-5. 2003
    ..This appears to contradict frequent observations of normal or near-normal pH levels in patients with chronic hypercapnia...
  92. ncbi request reprint Validity of asthma diagnoses recorded in the Medical Services database of Quebec
    Lucie Blais
    Universite de Montreal, Quebec, Canada
    Pharmacoepidemiol Drug Saf 15:245-52. 2006
    ..Results tended to be lower for 45-80 years old patients. We conclude that diagnoses recorded in the Medical Services database of Quebec are valid to identify patients with asthma...
  93. doi request reprint Occupational respiratory infections
    Anete Trajman
    Pró reitoria de Saúde, Gama Filho University, Rio de Janeiro, Brazil
    Curr Opin Pulm Med 16:226-34. 2010
    ....
  94. ncbi request reprint Interferon-gamma release assays: what is their role in the diagnosis of active tuberculosis?
    Madhukar Pai
    Clin Infect Dis 44:74-7. 2007
  95. ncbi request reprint Sputum induction: simpler, cheaper, and safer--but is it better?
    Dick Menzies
    Am J Respir Crit Care Med 167:676-7. 2003
  96. pmc Commercial serological antibody detection tests for the diagnosis of pulmonary tuberculosis: a systematic review
    Karen R Steingart
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, California, United States of America
    PLoS Med 4:e202. 2007
    ..Currently, dozens of distinct commercial antibody detection tests are sold in developing countries. The question is "do they work?"..
  97. pmc Molecular epidemiology of tuberculosis in Montreal
    Sophie Kulaga
    CMAJ 167:353-4. 2002
  98. ncbi request reprint The utility and interpretation of tuberculin skin tests in the Middle East
    Hamdan Al-Jahdali
    Division of Pulmonary, Department of Medicine, King Fahad National Guard Hospital, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia
    Am J Infect Control 33:151-6. 2005
    ....
  99. pmc Tuberculosis among health-care workers in low- and middle-income countries: a systematic review
    Rajnish Joshi
    Division of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, California, United States of America
    PLoS Med 3:e494. 2006
    ..Most health-care facilities in these countries lack resources to prevent nosocomial transmission of tuberculosis (TB)...
  100. ncbi request reprint Management of latent tuberculosis infection in immigrants
    Dick Menzies
    N Engl J Med 348:1289-92; author reply 1289-92. 2003