M J Meaney

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    M J Meaney
    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Centre, Department of Psychiatry and McGill Centre for the Study of Behavior, Genes and Environment, McGill University, Montreal, Canada
    Annu Rev Neurosci 24:1161-92. 2001
  2. pmc Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors
    F Champagne
    Developmental Neuroendocrinology Laboratory and McGill Program for the Study of Behavior, Genes, and Environment, Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Montreal, QC, Canada
    Proc Natl Acad Sci U S A 98:12736-41. 2001
  3. ncbi Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin
    M J Meaney
    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Center, McGill University, Montreal, Canada
    J Neurosci 20:3926-35. 2000
  4. ncbi Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivity
    S J Lupien
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
    J Clin Endocrinol Metab 82:2070-5. 1997
  5. ncbi Like mother, like daughter: evidence for non-genomic transmission of parental behavior and stress responsivity
    F Champagne
    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Center, Departments of Psychiatry, and Neurology and Neurosurgery, McGill University, Montreal, PQ H4H 1R3, Canada
    Prog Brain Res 133:287-302. 2001
  6. ncbi Long-term effects of BIBN-99, a selective muscarinic M2 receptor antagonist, on improving spatial memory performance in aged cognitively impaired rats
    W B Rowe
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada H4H 1R3
    Behav Brain Res 145:171-8. 2003
  7. ncbi Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites
    I C Weaver
    McGill Program for the Study of Behavior, Genes and Environment, Douglas Hospital Research Centre, Department of Psychiatry, McGill University, 6875 LaSalle Blvd, Montreal, Quebec, Canada H4H 1R3
    Mol Cell Endocrinol 185:205-18. 2001
  8. ncbi Glucocorticoid receptors in bovine adrenal medullary cells in culture: regulation by cyclic nucleotides
    K Betito
    McGill University, Department of Pharmacology and Therapeutics, Montreal, Quebec, Canada
    Neuroscience 54:263-73. 1993
  9. ncbi Partial reversal of the effect of maternal care on cognitive function through environmental enrichment
    T W Bredy
    Douglas Hospital Research Centre, Department of Psychiatry, McGill University, 6875 Boulevard LaSalle, Montreal, Canada H4H 1R3
    Neuroscience 118:571-6. 2003
  10. ncbi Influence of naturally occurring variations in maternal care on prepulse inhibition of acoustic startle and the medial prefrontal cortical dopamine response to stress in adult rats
    T Y Zhang
    Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Montreal, Quebec, H4H 1R3 Canada
    J Neurosci 25:1493-502. 2005

Collaborators

Detail Information

Publications15

  1. ncbi Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    M J Meaney
    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Centre, Department of Psychiatry and McGill Centre for the Study of Behavior, Genes and Environment, McGill University, Montreal, Canada
    Annu Rev Neurosci 24:1161-92. 2001
    ..These findings provide evidence for the importance of parental care as a mediator of the effects of environmental adversity on neural development...
  2. pmc Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors
    F Champagne
    Developmental Neuroendocrinology Laboratory and McGill Program for the Study of Behavior, Genes, and Environment, Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Montreal, QC, Canada
    Proc Natl Acad Sci U S A 98:12736-41. 2001
    ....
  3. ncbi Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin
    M J Meaney
    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Center, McGill University, Montreal, Canada
    J Neurosci 20:3926-35. 2000
    ..Thus, these findings suggest that postnatal handling might alter glucocorticoid receptor gene expression via cAMP-PKA pathways involving the activation of NGFI-A and AP-2...
  4. ncbi Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivity
    S J Lupien
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Canada
    J Clin Endocrinol Metab 82:2070-5. 1997
    ..They also suggest that an altered cortisol responsivity to acute and/or chronic stress, with its detrimental effects on memory, could be an important factor explaining the genesis of memory deficits in aged populations...
  5. ncbi Like mother, like daughter: evidence for non-genomic transmission of parental behavior and stress responsivity
    F Champagne
    Developmental Neuroendocrinology Laboratory, Douglas Hospital Research Center, Departments of Psychiatry, and Neurology and Neurosurgery, McGill University, Montreal, PQ H4H 1R3, Canada
    Prog Brain Res 133:287-302. 2001
    ....
  6. ncbi Long-term effects of BIBN-99, a selective muscarinic M2 receptor antagonist, on improving spatial memory performance in aged cognitively impaired rats
    W B Rowe
    Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada H4H 1R3
    Behav Brain Res 145:171-8. 2003
    ..Together, these studies help provide further insight into possible mechanism(s) of reference memory and its potential clinical usefulness...
  7. ncbi Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites
    I C Weaver
    McGill Program for the Study of Behavior, Genes and Environment, Douglas Hospital Research Centre, Department of Psychiatry, McGill University, 6875 LaSalle Blvd, Montreal, Quebec, Canada H4H 1R3
    Mol Cell Endocrinol 185:205-18. 2001
    ..This paper summarizes the evidence in favor of these pathways as well as recent studies describing regulatory targets on the promoter region of the rat hippocampal glucocorticoid receptor gene...
  8. ncbi Glucocorticoid receptors in bovine adrenal medullary cells in culture: regulation by cyclic nucleotides
    K Betito
    McGill University, Department of Pharmacology and Therapeutics, Montreal, Quebec, Canada
    Neuroscience 54:263-73. 1993
    ..abstract truncated at 400 words)..
  9. ncbi Partial reversal of the effect of maternal care on cognitive function through environmental enrichment
    T W Bredy
    Douglas Hospital Research Centre, Department of Psychiatry, McGill University, 6875 Boulevard LaSalle, Montreal, Canada H4H 1R3
    Neuroscience 118:571-6. 2003
    ..These findings provide evidence for the reversal of the effects of reduced maternal investment in early life on cognitive function in adulthood. Such effects might involve compensatory changes associated with peripubertal enrichment...
  10. ncbi Influence of naturally occurring variations in maternal care on prepulse inhibition of acoustic startle and the medial prefrontal cortical dopamine response to stress in adult rats
    T Y Zhang
    Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Montreal, Quebec, H4H 1R3 Canada
    J Neurosci 25:1493-502. 2005
    ....
  11. ncbi Can poverty get under your skin? basal cortisol levels and cognitive function in children from low and high socioeconomic status
    S J Lupie
    Laboratory of Human Psychoneuroendocrine Research, Douglas Hospital McGill University, LaSalle, Montreal, Canada
    Dev Psychopathol 13:653-76. 2001
    ....
  12. ncbi Nature, nurture, and the disunity of knowledge
    M J Meaney
    Program for the Study of Behavior, Genes and Environment, Douglas Hospital Research Centre, McGill University, Montreal, Canada H4H 1R3
    Ann N Y Acad Sci 935:50-61. 2001
    ..More sophisticated models reflecting the inevitable interdependence of gene and environment are essential if we are to realize the potential offered by today's technological advances...
  13. doi Epigenetic programming of phenotypic variations in reproductive strategies in the rat through maternal care
    N M Cameron
    Sackler Program for Epigenetics and Psychobiology at McGill University and Douglas University Mental Health Institute, McGill University, Montreal, Canada
    J Neuroendocrinol 20:795-801. 2008
    ..The tissue-specific nature of such effects may underlie the co-ordinated variation in multiple forms of reproductive function, resulting in distinct reproductive strategies...
  14. ncbi Acute modulation of aged human memory by pharmacological manipulation of glucocorticoids
    S J Lupien
    Laboratory of Human Psychoneuroendocrine Research, Douglas Hospital Research Center, Department of Psychiatry, McGill University, LaSalle, Verdun, Quebec H4H 1R3, Canada
    J Clin Endocrinol Metab 87:3798-807. 2002
    ..These results suggest that memory function in elderly humans can be intensely modulated by pharmacological manipulation of glucocorticoids, although the direction of these effects depends on the cortisol history of each individual...
  15. ncbi Neurotensin receptor levels as a function of brain aging and cognitive performance in the Morris water maze task in the rat
    W B Rowe
    Memory Pharmaceuticals, 100 Philips Parkway, Montvale, NJ 07645, USA
    Peptides 27:2415-23. 2006
    ....