Luke Martin McCaffrey

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis
    Luke Martin McCaffrey
    Rosalind and Morris Goodman Cancer Research Centre, Department of Oncology, McGill University, Montreal H3A 1A3, Canada
    Cancer Cell 22:601-14. 2012
  2. doi request reprint Epithelial organization, cell polarity and tumorigenesis
    Luke Martin McCaffrey
    Department of Oncology, Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada
    Trends Cell Biol 21:727-35. 2011

Collaborators

Detail Information

Publications3

  1. pmc Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis
    Luke Martin McCaffrey
    Rosalind and Morris Goodman Cancer Research Centre, Department of Oncology, McGill University, Montreal H3A 1A3, Canada
    Cancer Cell 22:601-14. 2012
    ..Importantly, Par3 expression is significantly reduced in human breast cancers, which correlates with active aPKC and Stat3. These data identify Par3 as a regulator of signaling pathways relevant to invasive breast cancer...
  2. doi request reprint Epithelial organization, cell polarity and tumorigenesis
    Luke Martin McCaffrey
    Department of Oncology, Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada
    Trends Cell Biol 21:727-35. 2011
    ..3D ex vivo culture systems can now faithfully recapitulate epithelial organ morphogenesis, providing a powerful approach to study both normal development and the initiating events in carcinogenesis...